CA Winnipeg Fernyhough P

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CA Winnipeg Fernyhough P

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Dept. of Pharmacology and Therapeutics

University of Manitoba

Division of Neurodegenerative Disorders

Address St Boniface Research Centre

R4046 – 351 Tache, MB R2H 2A6

City Winnipeg
State/Prov Manitoba (MB)
Country Canada
Weblink
Contact Fernyhough Paul
Team
Team previous Chowdhury Subir Kumar, Eli A
Status 2 Power-O2k 2007-
Oroboros Events IOC79
Topics Neurodegenerative disease with focus on diabetes


O2k-Publications

 PublishedReference
Roy Chowdhury 2018 Mol Cell Neurosci2018Roy Chowdhury S, Djordjevic J, Thomson E, Smith DR, Albensi BC, Fernyhough P (2018) Depressed mitochondrial function and electron transport Complex II-mediated H2O2 production in the cortex of type 1 diabetic rodents. Mol Cell Neurosci 90:49-59.
Calcutt 2017 J Clin Invest2017Calcutt NA, Smith DR, Frizzi K, Sabbir MG, Chowdhury SK, Mixcoatl-Zecuatl T, Saleh A, Muttalib N, Van der Ploeg R, Ochoa J, Gopaul A, Tessler L, Wess J, Jolivalt CG, Fernyhough P (2017) Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest 127:608-22.
Djordjevic 2017 Neuroscience2017Djordjevic J, Thomson E, Chowdhury SR, Snow WM, Perez C, Wong TP, Fernyhough P, Albensi BC (2017) Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease. Neuroscience 361:81-92.
Chowdhury 2015 Biosci Rep2015Chowdhury SK, Djordjevic J, Albensi B, Fernyhough P (2015) Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria. Biosci Rep 36:e00286.
Alandijany 2013 J Neurovirol2013Alandijany T, Kammouni W, Roy Chowdhury SK, Fernyhough P, Jackson AC (2013) Mitochondrial dysfunction in rabies virus infection of neurons. J Neurovirol 19:537-49.
Chowdhury 2013 Neurobiol Dis2013Chowdhury SK, Smith DR, Fernyhough P (2013) The role of aberrant mitochondrial bioenergetics in diabetic neuropathy. Neurobiol Dis 51:56-65.
Akude 2011 Diabetes2011Akude E, Zherebitskaya E, Chowdhury SK, Smith DR, Dobrowsky RT, Fernyhough P (2011) Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats. Diabetes 60:288-97.
Roy Chowdhury 2011 Mitochondrion2011Roy Chowdhury SK, Dobrowsky RT, Fernyhough P (2011) Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes. Mitochondrion 11:845-54.
Fernyhough 2010 Expert Rev Endocrinol Metab2010Fernyhough P, Roy Chowdhury SK, Schmidt RE (2010) Mitochondrial stress and the pathogenesis of diabetic neuropathy. Expert Rev Endocrinol Metab 5:39-49.
Chowdhury 2010 Diabetes2010Chowdhury SK, Zherebitskaya E, Smith DR, Akude E, Chattopadhyay S, Jolivalt CG, Calcutt NA, Fernyhough P (2010) Mitochondrial respiratory chain dysfunction in dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatment. Diabetes 59:1082-91.
Chowdhury 2010 Am J Physiol Endocrinol Metab2010Chowdhury SK, Sangle GV, Xie X, Stelmack GL, Halayko AJ, Shen GX (2010) Effects of extensively oxidized low-density lipoprotein on mitochondrial function and reactive oxygen species in porcine aortic endothelial cells. Am J Physiol Endocrinol Metab 298:E89-98.
Drahota 2002 J Bioenerg Biomembr2002Drahota Z, Chowdhury SK, Floryk D, Mrácek T, Wilhelm J, Rauchova H, Lenaz G, Houstek J (2002) Glycerophosphate-dependent hydrogen peroxide production by brown adipose tissue mitochondria and its activation by ferricyanide. J Bioenerg Biomembr 34:105-13.
Chowdhury 2000 Clin Chim Acta2000Chowdhury SK, Drahota Z, Floryk D, Calda P, Houstek J (2000) Activities of mitochondrial oxidative phosphorylation enzymes in cultured amniocytes. Clin Chim Acta 298:157-73.

O2k-Abstracts

update please