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Hinkle 1972 J Biol Chem

From Bioblast
Publications in the MiPMap
Hinkle PC, Kim JJ, Racker E (1972) Ion transport and respiratory control in vesicles formed from cytochrome oxidase and phospholipids. J Biol Chem 247:1338-9.

Β» PMID: 4334497 Open Access; PDF

Hinkle PC, Kim JJ, Racker E (1972) J Biol Chem

Abstract: Vesicles formed from cytochrome oxidase and phospholipids catalyzed the oxidation of reduced cytochrome c in a manner similar to that of intact mitochondria. A respiration-dependent release of protons and uptake of potassium ions were observed in the presence of valinomycin with reduced 1,4-naphthoquinone-2-sulfonate as reductant for cytochrome c. With ascorbate as reductant 3- to 5-fold stimulation of respiration was observed on addition of uncouplers or ionophorous agents. β€’ Keywords: Ion transport, Respiratory control, Cytochrome oxidase, Phospholipids, Vesicles


Labels: MiParea: Respiration 


Organism: Bovines  Tissue;cell: Heart  Preparation: Isolated mitochondria, SMP  Enzyme: Complex IV;cytochrome c oxidase  Regulation: Ion;substrate transport, Substrate  Coupling state: OXPHOS 


Made history