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CH Basel Eckert A

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CH Basel Eckert A

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Psychiatrische UniversitÀtsklinik

Neurobiologisches Labor

Address Wilhelm Klein-Str. 27, 4025
City Basel
State/Prov
Country Switzerland
Weblink
Contact Eckert Anne
Team Baysang Ginette, Ittner LM, Lim YA, Meier Fides, Rhein Virgine, Schwarz Dennis
Team previous
Status O2k 2005-
Oroboros Events MiPschool 2007, IOC35, IOC31
Topics Alzheimer's disease (AD)


O2k-Publications

 PublishedReference
Brand 2020 J Clin Med2020Brand S, Ebner K, Mikoteit T, Lejri I, Gerber M, Beck J, Holsboer-Trachsler E, Eckert A (2020) Influence of regular physical activity on mitochondrial activity and symptoms of burnout-an interventional pilot study. J Clin Med 9:E667.
Derungs 2017 Mol Psychiatry2017Derungs R, Camici GG, Spescha RD, Welt T, Tackenberg C, SpÀni C, Wirth F, Grimm A, Eckert A, Nitsch RM, Kulic L (2017) Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. Mol Psychiatry 22:605-14.
Grimm 2016 Methods Mol Biol2016Grimm A, Schmitt K, Eckert A (2016) Advanced mitochondrial respiration assay for evaluation of mitochondrial dysfunction in Alzheimer's disease. Methods Mol Biol 1303:171-83.
Hirzel 2013 J Recept Signal Transduct Res2013Hirzel E, Lindinger PW, Maseneni S, Giese M, Rhein VV, Eckert A, Hoch M, KrĂ€henbĂŒhl S, Eberle AN (2013) Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes. J Recept Signal Transduct Res 33:304-12.
Leuner 2012 Mol Neurobiol2012Leuner K, Schulz K, SchĂŒtt T, Pantel J, Prvulovic D, Rhein V, Savaskan E, Czech C, Eckert A, MĂŒller WE (2012) Peripheral mitochondrial dysfunction in Alzheimer's disease: focus on lymphocytes. Mol Neurobiol 46:194-204.
Lim 2011 PloS One2011Lim YA, Grimm A, Giese M, Mensah-Nyagan AG, Villafranca JE, Ittner LM, Eckert A, Götz J (2011) Inhibition of the mitochondrial enzyme ABAD restores the amyloid-ÎČ-mediated deregulation of estradiol. PloS One 6:e28887.
Rhein 2010 PloS One2010Rhein V, Giese M, Baysang G, Meier F, Rao S, Schulz KL, Hamburger M, Eckert A (2010) Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure. PloS One 5:e12359.
Lim 2010 Proteomics2010Lim YA, Rhein V, Baysang G, Meier F, Poljak A, Raftery MJ, Guilhaus M, Ittner LM, Eckert A, Goetz J (2010) Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics 10:1621-33.
Hauptmann 2009 Neurobiol Aging2009Hauptmann S, Scherping I, Dröse S, Brandt U, Schulz KL, Jendrach M, Leuner K, Eckert A, MĂŒller WE (2009) Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice. Neurobiol Aging 30:1574-86.
Rhein 2009 Cell Mol Neurobiol2009Rhein V, Baysang G, Rao S, Meier F, Bonert A, MĂŒller-Spahn F, Eckert A (2009) Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells. Cell Mol Neurobiol 29:1063-71.
Rhein 2009 Proc Natl Acad Sci U S A2009Rhein V, Song X, Wiesner A, Ittner LM, Baysang G, Meier F, Ozmen L, Bluethmann H, Dröse S, Brandt U, Savaskan E, Czech C, Götz J, Eckert A (2009) Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proc Natl Acad Sci U S A 106:20057-62.
Rhein 2008 Alzh Dement2008Rhein V, Baysang G, Meier F, Ozmen L, Bluethmann H, Dröse S, Brandt U, MĂŒller-Spahn F, Czech C, Goetz J, Eckert A (2008) P2-140: Mitochondrial failure in a transgenic mice model of Alzheimer's disease with plaques and tangles. Alzh Dement 4 Suppl: T411
Eckert 2008 J Mol Med2008Eckert A, Hauptmann S, Scherping I, Meinhardt J, Rhein V, Dröse S, Brandt U, FĂ€ndrich M, MĂŒller WE, Götz J (2008) Oligomeric and fibrillar species of beta-amyloid (Abeta42) both impair mitochondrial function in P301L tau transgenic mice. J Mol Med 86:1255-67.
David 2005 J Biol Chem2005David DC, Hauptmann S, Scherping I, Schuessel K, Keil U, Rizzu P, Ravid R, Dröse S, Brandt U, Muller WE, Eckert A, Götz J (2005) Proteomic and functional analysis reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem 280:23802-14.

O2k-Abstracts

update please