Acyl-CoA dehydrogenase

From Bioblast

high-resolution terminology - matching measurements at high-resolution

Acyl-CoA dehydrogenase


Acyl-CoA dehydrogenases ACADs are localized in the mitochondrial matrix. Several ACADs are distinguished: short-chain (SCAD), medium-chain (MCAD), and long-chain (LCAD). ACAD9 is expressed in human brain. ACADs catalyze the reaction

acyl-CoA + FAD β†’ trans-2-enoyl-CoA + FADH2

Abbreviation: ACAD

Reference: Wanders RJ, Ruiter JP, IJLst L, Waterham HR, Houten SM (2010) The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results. J Inherit Metab Dis 33:479-94. doi: 10.1007/s10545-010-9104-8. PMID: 20490924

MitoPedia topics: Enzyme 

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