Banerjee 2015 Placenta

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Banerjee A, Weidinger A, Hofer M, Steinborn R, Lindenmair A, Hennerbichler-Lugscheider S, Eibl J, Redl H, Kozlov AV, Wolbank S (2015) Different metabolic activity in placental and reflected regions of the human amniotic membrane. Placenta 36:1329-32.

» PMID: 26386652

Banerjee A*, Weidinger A, Hofer M, Steinborn R, Lindenmair A, Hennerbichler-Lugscheider S, Eibl J, Redl H, Kozlov AV, Wolbank S (2015) Placenta

Abstract: Cells of the human amniotic membrane (hAM) have stem cell characteristics with low immunogenicity and anti-inflammatory properties. While hAM is an excellent source for tissue engineering, so far, its sub-regions have not been taken into account. We show that placental and reflected hAM differ distinctly in morphology and functional activity, as the placental region has significantly higher mitochondrial activity, however significantly less reactive oxygen species. Since mitochondria may participate in processes such as cell rescue, we speculate that amniotic sub-regions may have different potential for tissue regeneration, which may be crucial for clinical applications.

Keywords: Human amniotic membrane, Mitochondrial respiration, Stem cell, Tissue regeneration

O2k-Network Lab: AT Vienna Kozlov AV


Labels: MiParea: Respiration 

Stress:Oxidative stress;RONS  Organism: Human  Tissue;cell: Genital  Preparation: Intact cells, Permeabilized tissue 


Coupling state: ROUTINE, OXPHOS, ET  Pathway:HRR: Oxygraph-2k 


Clarification

  • Banerjee A refers to Banerjee Asmita (Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, AUVA Research Center, Vienna, Austria) and not Banerjee Anindita