| Cardoso LHD, Gnaiger E (2024) OXPHOS coupling and uncoupling. Bioenerg Commun 2024.5. https://doi.org/10.26124/bec.2024-0005 |
» Bioenerg Commun 2024.05. 
published online 2024-08-09
Cardoso Luiza HD, Gnaiger Erich (2024) Bioenerg Commun
Abstract: 
https://doi.org/10.26124/bec.2024-0005
Coupling of OXPHOS is classically studied by comparing ADP-stimulated O2 flux (OXPHOS capacity P at saturating ADP and Pi concentrations) with non-phosphorylating LEAK respiration L, maintained mainly to compensate for the proton leak at high chemiosmotic potential in mitochondrial preparations supplied with fuel substrates to support mitochondrial electron transfer. However, measurement of the non-coupled electron transfer capacity E (ET capacity at collapsed chemiosmotic potential) yields additional information on coupling, since ET capacity may exceed OXPHOS capacity.
• Bioblast editor: Tindle-Solomon L • O2k-Network Lab: AT Innsbruck Oroboros
ORCID: 
Cardoso Luiza HD, Gnaiger Erich
MitoFit Preprint
Spotlight
- Davis MS, Barrett MR, Bayly WM, Bolinger A (2024) Effect of selected fluorophores on equine skeletal muscle mitochondrial respiration. Bioenerg Commun 2024.2. https://doi.org/10.26124/bec:2024-0002
Labels: MiParea: Respiration
Regulation: Coupling efficiency;uncoupling
Coupling state: LEAK, OXPHOS, ET
Gnaiger 2024 MitoFit
