Carnitine acyltransferase

From Bioblast


high-resolution terminology - matching measurements at high-resolution


Carnitine acyltransferase

Description

Carnitine acyltransferases mediate the transport of long-chain fatty acids across the inner mt-membrane by binding them to carnitine. First, long-chain fatty acids are activated by an energy-requiring step in which the fatty acid ester of CoA is formed enzymatically at the expense of ATP. The fatty acids then pass through the inner mt-membrane and enter the mitochondria as carnitine esters (acylcarnitines). The fatty acyl group is then transferred from carnitine to intramitochondrial CoA and the resulting fatty acyl CoA is used as a substrate in the fatty acid oxidation (FAO) cycle in the mt-matrix.






MitoPedia topics: Enzyme 


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MitoPedia:FAT4BRAIN 

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