Elmer 2017 US Patent
|Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1.|
Abstract: The present invention relates to a succinate prodrug for use in the treatment or prevention of lactic acidosis.
Labels: MiParea: Respiration, Pharmacology;toxicology
Organism: Human Tissue;cell: Heart, Blood cells, Fibroblast, Macrophage-derived, Platelet Preparation: Intact cells
Coupling state: LEAK, ROUTINE, OXPHOS, ET Pathway: S, ROX HRR: Oxygraph-2k