- high-resolution terminology - matching measurements at high-resolution
Fatty acid oxidation pathway control state
Description
In the fatty acid oxidation pathway control state (F- or FAO-pathway), one or several fatty acids are supplied to feed electrons into the F-junction through fatty acyl CoA dehydrogenase (reduced form FADH2), to electron transferring flavoprotein (CETF), and further through the Q-junction to Complex III (CIII). FAO not only depends on electron transfer through the F-junction (which is typically rate-limiting relative to the N-pathway branch), but simultaneously generates FADH2 and NADH and thus depends on N-junction throughput. Hence FAO can be inhibited completely by inhibition of Complex I (CI). In addition and independent of this source of NADH, the type N substrate malate is required at low concentration (0.1 mM) as a co-substrate for FAO in mt-preparations, since accumulation of Acetyl-CoA inhibits FAO in the absence of malate. Malate is oxidized in a reaction catalyzed by malate dehydrogenase to oxaloacetate (yielding NADH), which then stimulates the entry of Acetyl-CoA into the TCA cycle catalyzed by citrate synthase. Peroxysomal β-oxidation carries out few β-oxidation cycles, thus shortening very-long-chain fatty acids (>C20) for entry into mitochondrial β-oxidation. Oxygen consumption by peroxisomal acyl-CoA oxidase is considered as residual oxygen consumption rather than cell respiration.
Abbreviation: F, FAO
Reference: Electron-transfer-pathway state, Gnaiger 2020 BEC MitoPathways
MitoPedia concepts:
Respiratory state,
SUIT state,
Recommended
MitoPedia topics:
EAGLE
Communicated by Gnaiger E 2016-05-09, edited 2016-11-09, 2018-02-25.
FL
FAO pathway in the LEAK state can be evaluated in the following SUIT protocols:
FP
FAO pathway in the OXPHOS state can be evaluated in the following SUIT protocols:
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- DL-Protocol for isolated mitochondria and tissue homogenate (mt): SUIT-002 O2 mt D005
- DL-Protocol for permeabilized fibers (pfi): SUIT-002 O2 pfi D006
- DL-Protocol for permeabilized cells (pce): SUIT-002 O2 ce-pce D007
- DL-Protocol for permeabilized fibers (pfi): SUIT-005 O2 pfi D011
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FE
FAO pathway in the ET state can be evaluated in the following SUIT protocols:
Discussion
- What is the difference between the abbreviations F, F(N) and FN?
- F: Fatty acid oxidation with low concentration of Malate.
- F(N): Fatty acid oxidation with low or high concentration of Malate. In the case of permeabilized fibers (pfi), high concentration of Malate is required.
- FN: Fatty acid oxidation is combined with high concentration of N-linked substrates such as Pyruvate, Glutamate and Malate.
- »Publications: FAO, F-pathway control state
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| Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
|---|---|---|---|---|---|---|---|
| Shabalina 2024 Biochim Biophys Acta Bioenerg | 2024 | Shabalina IG, Jiménez B, Sousa-Filho CPB, Cannon B, Nedergaard J (2024) In isolated brown adipose tissue mitochondria UCP1 is not essential for nor involved in the uncoupling effects of the classical uncouplers FCCP and DNP. Biochim Biophys Acta Bioenerg [Epub ahead of print]. https://doi.org/10.1016/j.bbabio.2024.149516 | ET LEAK OXPHOS | F N | Isolated mitochondria | Mouse | Fat |
| Visker 2024 Exp Physiol | 2024 | Visker JR, Leszczynski EC, Wellette-Hunsucker AG, McPeek AC, Quinn MA, Kim SH, Bazil JN, Ferguson DP (2024) Postnatal growth restriction alters myocardial mitochondrial energetics in mice. https://doi.org/10.1113/ep091304 | LEAK OXPHOS | F N S NS | Isolated mitochondria | Mouse | Heart |
| Patil 2024 J Exp Biol | 2024 | Patil YN, Gnaiger E, Landry AP, Leno ZJ, Hand SC (2024) OXPHOS capacity is diminished and the phosphorylation system inhibited during diapause in an extremophile, embryos of Artemia franciscana. J Exp Biol 227:jeb.245828. https://doi.org/10.1242/jeb.245828 | LEAK OXPHOS ET | F N S NS | Homogenate Isolated mitochondria | Artemia | |
| Al-Sabri 2024 Sci Rep | 2024 | Al-Sabri MH, Ammar N, Korzh S, Alsehli AM, Hosseini K, Fredriksson R, Mwinyi J, Williams MJ, Boukhatmi H, Schiöth HB (2024) Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes. https://doi.org/10.1038/s41598-024-53446-w | LEAK OXPHOS ET | F N S Gp NS ROX | Permeabilized tissue | Drosophila | Skeletal muscle |
| Meszaros 2024 Transpl Int | 2024 | Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. Transpl Int 37:12380. https://doi.org/10.3389/ti.2024.12380 | LEAK OXPHOS ET | N S NS F ROX | Homogenate | Human | Liver |
| Natsui 2024 Physiol Rep | 2024 | Natsui H, Watanabe M, Yokota T, Tsuneta S, Fumoto Y, Handa H, Shouji M, Koya J, Nishino K, Tatsuta D, Koizumi T, Kadosaka T, Nakao M, Koya T, Temma T, Ito YM, Kanako HC, Hatanaka Y, Yasushige S, Wakasa S, Miura S, Masuda T, Nishioka N, Naraoka S, Ochi K, Kudo T, Ishikawa T, Anzai T (2024) Influence of epicardial adipose tissue inflammation and adipocyte size on postoperative atrial fibrillation in patients after cardiovascular surgery. Physiol Rep 12:e15957. https://doi.org/10.14814/phy2.15957 | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Fat |
| Xia 2024 Nat Metab | 2024 | Xia W, Veeragandham P, Cao Y, Yayun Xu Y, Rhyne TE, Qian J, Hung C-W, Zhao P, Jones Y, Gao H, Liddle C, Yu RT, Downes M, Evans RM, Rydén M, Wabitsch M, Wang Z, Hakozaki H, Schöneberg J, Reilly SM, Huang J, Saltiel AR (2024) Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation. Nat Metab 6:273–89. https://doi.org/10.1038/s42255-024-00978-0 | LEAK ROUTINE ET | F | Isolated mitochondria Intact cells | Human Mouse | Fat |
| Mahapatra 2024 J Gerontol A Biol Sci Med Sci | 2024 | Mahapatra G, Gao Z, Bateman JR 3rd, Lockhart SN, Bergstrom J, Piloso JE, Craft S, Molina AJA (2024) Peripheral blood cells from older adults exhibit sex-associated differences in mitochondrial function. J Gerontol A Biol Sci Med Sci [Epub ahead of print]. https://doi.org/10.1093/gerona/glae098 | ROUTINE OXPHOS ET | F N Gp CIV NS Other combinations ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Jiang 2024 Nat Metab | 2024 | Jiang S, Yuan T, Rosenberger FA, Mourier A, Dragano NRV, Kremer LS, Rubalcava-Gracia D, Hansen FM, Borg M, Mennuni M, Filograna R, Alsina D, Misic J, Koolmeister C, Papadea P, de Angelis MH, Ren L, Andersson O, Unger A, Bergbrede T, Di Lucrezia R, Wibom R, Zierath JR, Krook A, Giavalisco P, Mann M, Larsson NG (2024) Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity. Nat Metab [Epub ahead of print]. https://doi.org/10.1038/s42255-024-01038-3 | LEAK OXPHOS ET | F N S Gp Other combinations | Isolated mitochondria | Mouse | Liver |
| Thome 2024 JCI Insight | 2024 | Thome T, Vugman NA, Stone LE, Wimberly K, Scali ST, Ryan TE (2024) A tryptophan-derived uremic metabolite-Ahr-Pdk4 axis governs skeletal muscle mitochondrial energetics in chronic kidney disease. JCI Insight [Epub ahead of print]. https://doi.org/10.1172/jci.insight.178372 | LEAK OXPHOS | F N | Permeabilized tissue Isolated mitochondria | Human Mouse | Skeletal muscle |
| Liepinsh 2024 Br J Pharmacol | 2024 | Liepinsh E, Zvejniece L, Clemensson L, Ozola M, Vavers E, Cirule H, Korzh S, Skuja S, Groma V, Briviba M, Grinberga S, Liu W, Olszewski P, Gentreau M, Fredriksson R, Dambrova M, Schiöth HB (2024) Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver. Br J Pharmacol [Epub ahead of print]. https://doi.org/10.1111/bph.16363 | ET LEAK OXPHOS | F N S NS ROX | Homogenate | Mouse | Liver |
| Xu 2024 Sci Adv | 2024 | Xu G, Quan S, Schell J, Gao Y, Varmazyad M, Sreenivas P, Cruz D, Jiang H, Pan M, Han X, Palavicini JP, Zhao P, Sun X, Marchant ED, Rasmussen BB, Li G, Katsumura S, Morita M, Munkácsy E, Horikoshi N, Chocron ES, Gius D (2024) Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease. Sci Adv 10:eadj5942. https://doi.org/10.1126/sciadv.adj5942 | ET LEAK OXPHOS | F N ROX | Mouse | Liver | |
| Dulac 2024 J Physiol | 2024 | Dulac M, Hajj-Boutros G, Sonjak V, Faust A, Hussain SNA, Chevalier S, Dionne IJ, Morais JA, Gouspillou G (2024) A multimodal exercise countermeasure prevents the negative impact of head-down tilt bed rest on muscle volume and mitochondrial health in older adults. J Physiol [Epub ahead of print]. https://doi.org/10.1113/jp285897 | LEAK OXPHOS | F N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Leo 2024 MitoFit | 2024 | Leo E, Rychtarova L, Garcia-Souza LF, Åsander Frostner E, Elmér E, Gnaiger E (2024) High-resolution respirometry in a small-volume chamber. MitoFit Preprints 2024.4.v2. https://doi.org/10.26124/mitofit:2024-0004.v2 | ET LEAK ROUTINE OXPHOS | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Homogenate Isolated mitochondria Intact cells | Human Mouse | Heart Nervous system Blood cells HUVEC Platelet |
| Doan 2024 Nat Cardiovasc Res | 2024 | Doan KV, Luongo TS, Ts'olo TT, Lee WD, Frederick DW, Mukherjee S, Adzika GK, Perry CE, Gaspar RB, Walker N, Blair MC, Bye N, Davis JG, Holman CD, Chu Q, Wang L, Rabinowitz JD, Kelly DP, Cappola TP, Margulies KB, Baur JA (2024) Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics. Nat Cardiovasc Res [Epub ahead of print]. https://doi.org/10.1038/s44161-024-00542-9 | LEAK OXPHOS | F N S CIV | Homogenate Isolated mitochondria | Mouse | Heart |
| Kahl 2024 J Hepatol | 2024 | Kahl S, Straßburger K, Pacini G, Trinks N, Pafili K, Mastrototaro L, Dewidar B, Sarabhai T, Trenkamp S, Esposito I, Schlensak M, Granderath FA, Roden M (2024) Dysglycemia and liver lipid content determine the relationship of insulin resistance with hepatic OXPHOS capacity in obesity. J Hepatol [Epub ahead of print]. https://doi.org/10.1016/j.jhep.2024.08.012 | OXPHOS ET LEAK | F N S ROX | Permeabilized tissue | Human | Liver |
| Cardoso 2024 MitoFit FAO | 2024 | Cardoso LHD, Cecatto C, Ozola M, Korzh S, Zvejniece L, Gukalova B, Doerrier C, Dambrova M, Makrecka-Kuka M, Gnaiger E, Liepinsh E (2024) Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models. MitoFit Preprints 2023.10. https://doi.org/10.26124/mitofit:2023-0010.v2 | OXPHOS ET | F N S Gp | Homogenate | Mouse Rat Drosophila | Heart Nervous system Kidney |
| Perry 2024 JCI Insight | 2024 | Perry CE, Halawani SM, Mukherjee S, Ngaba LV, Lieu M, Lee WD, Davis JG, Adzika GK, Bebenek AN, Bazianos DD, Chen B, Mercado-Ayon E, Flatley LP, Suryawanshi AP, Ho I, Rabinowitz JD, Serai SD, Biko DM, Tamaroff J, DeDio A, Wade K, Lin KY, Livingston DJ, McCormack SE, Lynch DR, Baur JA (2024) NAD+ precursors prolong survival and improve cardiac phenotypes in a mouse model of Friedreich's Ataxia. JCI Insight 9:e177152. https://doi.org/10.1172/jci.insight.177152 | LEAK OXPHOS | F N S CIV | Isolated mitochondria | Mouse | Heart |
| Coulson 2024 J Exp Biol | 2024 | Coulson SZ, Guglielmo CG, Staples JF (2024) Migration increases mitochondrial oxidative capacity without increasing reactive oxygen species emission in a songbird. J Exp Biol 227:jeb246849. https://doi.org/10.1242/jeb.246849 | LEAK OXPHOS | F N S CIV | Isolated mitochondria | Birds | Skeletal muscle |
| Alanova 2024 Acta Physiol (Oxf) | 2024 | Alanova P, Alan L, Opletalova B, Bohuslavova R, Abaffy P, Matejkova K, Holzerova K, Benak D, Kaludercic N, Menabo R, Di Lisa F, Ostadal B, Kolar F, Pavlinkova G (2024) HIF-1α limits myocardial infarction by promoting mitophagy in mouse hearts adapted to chronic hypoxia. Acta Physiol (Oxf) [Epub ahead of print]. https://doi.org/10.1111/apha.14202 | ET LEAK OXPHOS | F N S CIV NS | Isolated mitochondria | Mouse | Heart |
| Samodelov 2024 Sci Rep | 2024 | Samodelov SL, Gai Z, De Luca F, Haldimann K, Hobbie SN, Müller D, Kullak-Ublick GA, Visentin M (2024) L-carnitine co-administration prevents colistin-induced mitochondrial permeability transition and reduces the risk of acute kidney injury in mice. Sci Rep 14:16444. https://doi.org/10.1038/s41598-024-67171-x | LEAK | S F | Isolated mitochondria | Mouse | Kidney |
| Zhao 2024 J Adv Res | 2024 | Zhao Y, Lu Z, Zhang H, Wang L, Sun F, Li Q, Cao T, Wang B, Ma H, You M, Zhou Q, Wei X, Li L, Liao Y, Yan Z, Liu D, Gao P, Zhu Z (2024) Sodium-glucose exchanger 2 inhibitor canagliflozin promotes mitochondrial metabolism and alleviates salt-induced cardiac hypertrophy via preserving SIRT3 expression. J Adv Res [Epub ahead of print]. https://doi.org/10.1016/j.jare.2024.04.030 | ET LEAK OXPHOS | F N S NS ROX | Isolated mitochondria | Mouse | Heart |
| Wang 2024 Adv Sci (Weinh) | 2024 | Wang H, Stevens T, Lu J, Roberts A, Van't Land C, Muzumdar R, Gong Z, Vockley J, Prochownik EV (2024) Body-wide inactivation of the Myc-like Mlx transcription factor network accelerates aging and increases the lifetime cancer incidence. Adv Sci (Weinh) [Epub ahead of print]. https://doi.org/10.1002/advs.202401593 | LEAK OXPHOS | F N S NS | Isolated mitochondria | Mouse | Fat Skeletal muscle Liver |
| Krause 2023 J Transl Med | 2023 | Krause J, Nickel A, Madsen A, Aitken-Buck HM, Stoter AMS, Schrapers J, Ojeda F, Geiger K, Kern M, Kohlhaas M, Bertero E, Hofmockel P, Hübner F, Assum I, Heinig M, Müller C, Hansen A, Krause T, Park DD, Just S, Aïssi D, Börnigen D, Lindner D, Friedrich N, Alhussini K, Bening C, Schnabel RB, Karakas M, Iacoviello L, Salomaa V, Linneberg A, Tunstall-Pedoe H, Kuulasmaa K, Kirchhof P, Blankenberg S, Christ T, Eschenhagen T, Lamberts RR, Maack C, Stenzig J, Zeller T (2023) An arrhythmogenic metabolite in atrial fibrillation. https://doi.org/10.1186/s12967-023-04420-z | LEAK OXPHOS | F N NS | Isolated mitochondria Intact cells | Human | Heart |
| Pereyra 2023 Am J Physiol Gastrointest Liver Physiol | 2023 | Pereyra AS, McLaughlin KL, Buddo KA, Ellis JM (2023) Medium-chain fatty acid oxidation is independent of L-carnitine in liver and kidney but not in heart and skeletal muscle. https://doi.org/10.1152/ajpgi.00105.2023 | LEAK ROUTINE OXPHOS | F N | Homogenate | Mouse | Heart Skeletal muscle Liver Kidney |
| Dewidar 2023 EBioMedicine | 2023 | Dewidar B, Mastrototaro L, Englisch C, Ress C, Granata C, Rohbeck E, Pesta D, Heilmann G, Wolkersdorfer M, Esposito I, Reina Do Fundo M, Zivehe F, Yavas A, Roden M (2023) Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseases. https://doi.org/10.1016/j.ebiom.2023.104714 | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle Liver |
| Fisher-Wellman 2023 Cancers (Basel) | 2023 | Fisher-Wellman KH, Kassai M, Hagen JT, Neufer PD, Kester M, Loughran TP Jr, Chalfant CE, Feith DJ, Tan SF, Fox TE, Ung J, Fabrias G, Abad JL, Sharma A, Golla U, Claxton DF, Shaw JJP, Bhowmick D, Cabot MC (2023) Simultaneous inhibition of ceramide hydrolysis and glycosylation synergizes to corrupt mitochondrial respiration and signal caspase driven cell death in drug-resistant acute myeloid leukemia. https://doi.org/10.3390/cancers15061883 | LEAK ROUTINE ET | F N NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
| Golomb 2023 Sci Rep | 2023 | Golomb BA, Sanchez Baez R, Schilling JM, Dhanani M, Fannon MJ, Berg BK, Miller BJ, Taub PR, Patel HH (2023) Mitochondrial impairment but not peripheral inflammation predicts greater Gulf War illness severity. https://doi.org/10.1038/s41598-023-35896-w | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Mancilla 2023 Physiol Rep | 2023 | Mancilla R, Pava-Mejia D, van Polanen N, de Wit V, Bergman M, Grevendonk L, Jorgensen J, Kornips E, Hoeks J, Hesselink MKC, Schrauwen-Hinderling VB (2023) Invasive and noninvasive markers of human skeletal muscle mitochondrial function. https://doi.org/10.14814/phy2.15734 | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Nollet 2023 Eur Heart J | 2023 | Nollet EE, Duursma I, Rozenbaum A, Eggelbusch M, Wüst RCI, Schoonvelde SAC, Michels M, Jansen M, van der Wel NN, Bedi KC, Margulies KB, Nirschl J, Kuster DWD, van der Velden J (2023) Mitochondrial dysfunction in human hypertrophic cardiomyopathy is linked to cardiomyocyte architecture disruption and corrected by improving NADH-driven mitochondrial respiration. https://doi.org/10.1093/eurheartj/ehad028 | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Heart |
| Moellering 2023 Arthritis Res Ther | 2023 | Moellering DR, Smith-Johnston K, Kelley C, Sammy MJ, Benedict J, Brock G, Johnson J, Baskin KK, Jarjour WN, Belury MA, Reiser PJ, Nagareddy PR, Hanaoka BY (2023) Association between skeletal muscle mitochondrial dysfunction and insulin resistance in patients with rheumatoid arthritis: a case-control study. https://doi.org/10.1186/s13075-023-03065-z | LEAK OXPHOS ET | F N CIV ROX | Permeabilized tissue | Human | Skeletal muscle |
| Kankuri 2023 Exp Mol Med | 2023 | Kankuri E, Finckenberg P, Leinonen J, Tarkia M, Björk S, Purhonen J, Kallijärvi J, Kankainen M, Soliymani R, Lalowski M, Mervaala E (2023) Altered acylcarnitine metabolism and inflexible mitochondrial fuel utilization characterize the loss of neonatal myocardial regeneration capacity. https://doi.org/10.1038/s12276-023-00967-5 | LEAK OXPHOS | F N S NS ROX | Isolated mitochondria | Mouse | Heart |
| Gemmink 2023 Mol Metab | 2023 | Gemmink A, Daemen S, Wefers J, Hansen J, van Moorsel D, Astuti P, Jorgensen JA, Kornips E, Schaart G, Hoeks J, Schrauwen P, Hesselink MKC (2023) Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity. https://doi.org/10.1016/j.molmet.2023.101727 | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Shi 2023 Redox Biol | 2023 | Shi L, Tao Z, Zheng L, Yang J, Hu X, Scott K, de Kloet A, Krause E, Collins JF, Cheng Z (2023) FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway. https://doi.org/10.1016/j.redox.2023.102727 | LEAK ET ROUTINE | F | Intact cells | Mouse | Fat |
| Horcas-Nieto 2023 Biochim Biophys Acta Mol Basis Dis | 2023 | Horcas-Nieto JM, Versloot CJ, Langelaar-Makkinje M, Gerding A, Blokzijl T, Koster MH, Baanstra M, Martini IA, Coppes RP, Bourdon C, van Ijzendoorn SCD, Kim P, Bandsma RHJ, Bakker BM (2023) Organoids as a model to study intestinal and liver dysfunction in severe malnutrition. https://doi.org/10.1016/j.bbadis.2022.166635 | LEAK ET OXPHOS | F | Mouse | Liver Other cell lines | |
| Ashok 2023 Mol Cell Biochem | 2023 | Ashok S, Raji SR, Manjunatha S, Srinivas G (2023) Impairment of substrate-mediated mitochondrial respiration in cardiac cells by chloroquine. https://doi.org/10.1007/s11010-023-04740-0 | OXPHOS | F N S NS ROX | Isolated mitochondria | Mouse | Heart |
| Robertson 2023 J Cell Sci | 2023 | Robertson GL, Riffle S, Patel M, Bodnya C, Marshall A, Beasley HK, Garza-Lopez E, Shao J, Vue Z, Hinton A, Stoll MS, de Wet S, Theart RP, Chakrabarty RP, Loos B, Chandel NS, Mears JA, Gama V (2023) DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs. https://doi.org/10.1242/jcs.260370 | LEAK ROUTINE OXPHOS ET | F N S DQ CIV NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Dreher 2023 Int J Obes (Lond) | 2023 | Dreher SI, Irmler M, Pivovarova-Ramich O, Kessler K, Jürchott K, Sticht C, Fritsche L, Schneeweiss P, Machann J, Pfeiffer AFH, Hrabě de Angelis M, Beckers J, Birkenfeld AL, Peter A, Niess AM, Weigert C, Moller A (2023) Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention. https://doi.org/10.1038/s41366-023-01271-y | OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle Fat |
| Frangos 2023 J Biol Chem | 2023 | Frangos SM, DesOrmeaux GJ, Holloway GP (2023) Acidosis attenuates CPT-I supported bioenergetics as a potential mechanism limiting lipid oxidation. https://doi.org/10.1016/j.jbc.2023.105079 | LEAK OXPHOS | F N S NS | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
| Noone 2023 Cell Signal | 2023 | Noone J, Rochfort KD, O'Sullivan F, O'Gorman DJ (2023) SIRT4 is a regulator of human skeletal muscle fatty acid metabolism influencing inner and outer mitochondrial membrane-mediated fusion. https://doi.org/10.1016/j.cellsig.2023.110931 | LEAK OXPHOS | F N ROX | Permeabilized cells | Human | Skeletal muscle |
| Nijholt 2023 Sci Rep | 2023 | Nijholt KT, Sánchez-Aguilera PI, Mahmoud B, Gerding A, Wolters JC, Wolters AHG, Giepmans BNG, Silljé HHW, de Boer RA, Bakker BM, Westenbrink BD (2023) A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exercise. https://doi.org/10.1038/s41598-023-45961-z | LEAK OXPHOS ET | F N | Isolated mitochondria | Mouse | Heart |
| Garcia-Roche 2023 PLoS One | 2023 | García-Roche M, Talmón D, Cañibe G, Astessiano AL, Mendoza A, Cassina A, Quijano C, Carriquiry M (2023) Hepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion. https://doi.org/10.1371/journal.pone.0290551 | LEAK OXPHOS ET | F N S NS ROX | Intact cells | Bovines | Liver |
| Tian 2023 Redox Biol | 2023 | Tian G, Zhou J, Quan Y, Kong Q, Li J, Xin Y, Wu W, Tang X, Liu X (2023) Voltage-dependent anion channel 1 (VDAC1) overexpression alleviates cardiac fibroblast activation in cardiac fibrosis via regulating fatty acid metabolism. https://doi.org/10.1016/j.redox.2023.102907 | F | Intact cells | Mouse | Heart Fibroblast | |
| Boykov 2023 Sci Rep | 2023 | Boykov IN, Montgomery MM, Hagen JT, Aruleba RT, McLaughlin KL, Coalson HS, Nelson MA, Pereyra AS, Ellis JM, Zeczycki TN, Vohra NA, Tan SF, Cabot MC, Fisher-Wellman KH (2023) Pan-tissue mitochondrial phenotyping reveals lower OXPHOS expression and function across cancer types. https://doi.org/10.1038/s41598-023-43963-5 | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Mouse | Heart Endothelial;epithelial;mesothelial cell |
| Kutschka 2023 Basic Res Cardiol | 2023 | Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, Eberl H, Rebs S, Streckfuss-Bömeke K, Schmitz W, Rehling P, Thum T, Higuchi T, Rabinowitz J, Maack C, Dudek J (2023) Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome. https://doi.org/10.1007/s00395-023-01017-x | LEAK OXPHOS ET | F N | Isolated mitochondria | Mouse | Heart |
| Bodis 2023 Diabetes Obes Metab | 2023 | Bódis K, Breuer S, Crepzia-Pevzner A, Zaharia OP, Schön M, Saatmann N, Altenhofen D, Springer C, Szendroedi J, Wagner R, Al-Hasani H, Roden M, Pesta D, Chadt A (2023) Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high-fat diet-fed mouse model. https://doi.org/10.1111/dom.15322 | LEAK OXPHOS ET | F N NS | Mouse | Fat | |
| Fromenty 2023 J Hepatol | 2023 | Fromenty B, Roden M (2023) Mitochondrial alterations in fatty liver diseases. J Hepatol 78:415-29. https://doi.org/10.1016/j.jhep.2022.09.020 | F | ||||
| Harmsen 2023 J Physiol | 2023 | Harmsen JF, Kotte M, Habets I, Bosschee F, Frenken K, Jorgensen JA, de Kam S, Moonen-Kornips E, Cissen J, Doligkeit D, van de Weijer T, Erazo-Tapia E, Buitinga M, Hoeks J, Schrauwen P (2023) Exercise training modifies skeletal muscle clock gene expression but not 24-hour rhythmicity in substrate metabolism of men with insulin resistance. https://doi.org/10.1113/jp285523 | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
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| Penniman 2019 Mol Metab | 2019 | Penniman CM, Suarez Beltran PA, Bhardwaj G, Junck TL, Jena J, Poro K, Hirshman MF, Goodyear LJ, O'Neill BT (2019) Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity. Mol Metab 30:203-220. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
| Wang 2019 Metabolism | 2019 | Wang D, Liu CD, Li HF, Tian ML, Pan JQ, Shu G, Jiang QY, Yin YL, Zhang L (2019) LSD1 mediates microbial metabolite butyrate-induced thermogenesis in brown and white adipose tissue. Metabolism 102:154011. | LEAK | F N | Isolated mitochondria | Mouse | Fat |
| Fang 2019 Nat Commun | 2019 | Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE, Mattson MP, Jasper H, Nilsen H, Bohr VA (2019) NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome. Nat Commun 10:5284. | LEAK OXPHOS | F N S CIV ROX | Homogenate | Mouse | Heart Nervous system Liver |
| Mayeuf-Louchart 2019 Cell Rep | 2019 | Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H (2019) Glycogen dynamics drives lipid droplet biogenesis during brown adipocyte differentiation. Cell Rep 29:1410-18. | LEAK OXPHOS | F N S NS | Permeabilized cells | Mouse | Fat |
| Tarpey 2019 J Biol Chem | 2019 | Tarpey MD, Amorese AJ, Balestrieri NP, Fisher-Wellman KH, Spangenburg EE (2019) Doxorubicin causes lesions in the electron transport system of skeletal muscle mitochondria that are associated with a loss of contractile function. J Biol Chem 294:19709-22. | LEAK ET | F N S CIV | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
| Nambu 2019 Eur J Pharmacol | 2019 | Nambu H, Takada S, Fukushima A, Matsumoto J, Kakutani N, Maekawa S, Shirakawa R, Nakano I, Furihata T, Katayama T, Yamanashi K, Obata Y, Saito A, Yokota T, Kinugawa S (2019) Empagliflozin restores lowered exercise endurance capacity via the activation of skeletal muscle fatty acid oxidation in a murine model of heart failure. Eur J Pharmacol 866:172810. | LEAK OXPHOS | F N NS | Permeabilized tissue | Mouse | Skeletal muscle |
| MiPNet21.06 SUIT RP | 2018-06-25 | | LEAK OXPHOS ET | F N S Gp CIV NS Other combinations | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria | ||
| Dandanell 2018 Scand J Med Sci Sports | 2018 | Dandanell S, Meinild-Lundby AK, Andersen AB, Lang PF, Oberholzer L, Keiser S, Robach P, Larsen S, Rønnestad BR, Lundby C (2018) Determinants of maximal whole-body fat oxidation in elite cross-country skiers: role of skeletal muscle mitochondria. Scand J Med Sci Sports 28:2494-504. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Keller 2018 Oxid Med Cell Longev | 2018 | Keller AC, Knaub LA, Scalzo RL, Hull SE, Johnston AE, Walker LA, Reusch JEB (2018) Sepiapterin improves vascular reactivity and insulin-stimulated glucose in wistar rats. Oxid Med Cell Longev 2018:7363485. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Rat | Endothelial;epithelial;mesothelial cell |
| Van Den Brink 2018 PLoS Genet | 2018 | Van Den Brink DM, Cubizolle A, Chatelain G, Davoust N, Girard V, Johansen S, Napoletano F, Dourlen P, Guillou L, Angebault-Prouteau C, Bernoud-Hubac N, Guichardant M, Brabet P, Mollereau B (2018) Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina. PLoS Genet 14:e1007627. | LEAK OXPHOS | F N S NS | Permeabilized cells | Mouse | Endothelial;epithelial;mesothelial cell |
| Tsuda 2018 J Cachexia Sarcopenia Muscle | 2018 | Tsuda M, Fukushima A, Matsumoto J, Takada S, Kakutani N, Nambu H, Yamanashi K, Furihata T, Yokota T, Okita K, Kinugawa S, Anzai T (2018) Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure. J Cachexia Sarcopenia Muscle 9:844-59. | OXPHOS LEAK | F N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Cardinale 2018 Front Physiol | 2018 | Cardinale DA, Larsen FJ, Schiffer TA, Morales-Alamo D, Ekblom B, Calbet JAL, Holmberg HC, Boushel R (2018) Superior intrinsic mitochondrial respiration in women than in men. Front Physiol 9:1133. | OXPHOS | F N NS | Isolated mitochondria | Human | Skeletal muscle |
| Merz 2018 Intensive Care Med Exp | 2018 | Merz T, Wepler M, Nußbaum B, Vogt J, Calzia E, Wang R, Szabo C, Radermacher P, McCook O (2018) Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis. Intensive Care Med Exp 6:43. | LEAK OXPHOS ET | F N S NS ROX | Homogenate | Pig | Kidney |
| Scalzo 2018 Physiol Rep | 2018 | Scalzo RL, Knaub LA, Hull SE, Keller AC, Hunter K, Walker LA, Reusch JEB (2018) Glucagon-like peptide-1 receptor antagonism impairs basal exercise capacity and vascular adaptation to aerobic exercise training in rats. Physiol Rep 6:e13754. | LEAK OXPHOS ET | F NS Other combinations | Permeabilized tissue | Rat | Heart |
| Larsen 2018 Physiol Rep | 2018 | Larsen S, Lundby AM, Dandanell S, Oberholzer L, Keiser S, Andersen AB, Haider T, Lundby C (2018) Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males. Physiol Rep 6:e13793. | OXPHOS ET LEAK | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Rocha 2018 J Physiol Biochem | 2018 | Rocha C, Koury OH, Scheede-Bergdahl C, Bergdahl A (2018) Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice. J Physiol Biochem 75:65-72. | LEAK OXPHOS ET | F N CIV NS ROX | Permeabilized tissue | Mouse | Heart |
| Brouwers 2018 Front Physiol | 2018 | Brouwers B, Stephens NA, Costford SR, Hopf ME, Ayala JE, Yi F, Xie H, Li JL, Gardell SJ, Sparks LM, Smith SR (2018) Elevated nicotinamide phosphoribosyl transferase in skeletal muscle augments exercise performance and mitochondrial respiratory capacity following exercise training. Front Physiol 9:704. | OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Barbeau 2018 Biochem J | 2018 | Barbeau PA, Miotto PM, Holloway GP (2018) Mitochondrial derived reactive oxygen species influence ADP sensitivity, but not CPT-I substrate sensitivity. Biochem J 475:2997-3008. | OXPHOS | F N NS | Permeabilized tissue | Mouse | Skeletal muscle |
| Cooper 2018 Exp Physiol | 2018 | Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE (2018) Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12. | OXPHOS ET LEAK | F N NS | Permeabilized tissue | Mouse | Nervous system |
| Miotto 2018 Thesis | 2018 | Miotto PM (2018) The influence of exercise and high fat feeding on the regulation of mitochondrial substrate sensitivity in skeletal muscle. PhD Thesis p185. | OXPHOS | F N NS | Permeabilized cells | Mouse | Skeletal muscle |
| Von Schulze 2018 J Physiol | 2018 | Von Schulze A, McCoin CS, Onyekere C, Allen J, Geiger P, Dorn GW, Morris EM, Thyfault JP (2018) Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1α, and BNIP3 mediated mitophagy. J Physiol 596:6157-71. | OXPHOS ET | F N NS | Isolated mitochondria | Mouse | Liver |
| Johnson 2018 J Mol Cell Cardiol | 2018 | Johnson JM, Ferrara PJ, Verkerke ARP, Coleman CB, Wentzler EJ, Neufer PD, Kew KA, de Castro Brás LE, Funai K (2018) Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome. J Mol Cell Cardiol 121:94-102. | OXPHOS ET | F N S NS | Isolated mitochondria | Mouse | Heart Skeletal muscle |
| Burney 2018 Thesis | 2018 | Burney E (2018) Characterization of mitochondrial metabolism in L6 rat myoblasts. Bachelor's Thesis p50. | LEAK ROUTINE OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells Intact cells | Rat | Other cell lines |
| Musi 2018 Aging Cell | 2018 | Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME (2018) Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell 17:e12840. | LEAK OXPHOS ET | F N S NS | Homogenate | Mouse | Nervous system |
| Manakov 2018 J Physiol Biochem | 2018 | Manakov D, Kolar D, Zurmanova J, Pravenec M, Novotny J (2018) Changes in the activity of some metabolic enzymes in the heart of SHR rat incurred by transgenic expression of CD36. J Physiol Biochem 74:479-89. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Rat | Heart |
| Nacarelli 2018 Geroscience | 2018 | Nacarelli T, Azar A, Altinok O, Orynbayeva Z, Sell C (2018) Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts. Geroscience 40:243-56. | OXPHOS | F N S NS | Isolated mitochondria | Human | Heart Fibroblast |
| Britto 2018 BMC Biol | 2018 | Britto FA, Cortade F, Belloum Y, Blaquière M, Gallot YS, Docquier A, Pagano AF, Jublanc E, Bendridi N, Koechlin-Ramonatxo C, Chabi B, Francaux M, Casas F, Freyssenet D, Rieusset J, Giorgetti-Peraldi S, Carnac G, Ollendorff V, Favier FB (2018) Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress. BMC Biol 16:65. https://doi.org/10.1186/s12915-018-0525-4 | LEAK OXPHOS | F N NS Other combinations | Permeabilized cells Isolated mitochondria | Mouse | Skeletal muscle |
| Apostolopoulou 2018 Thesis | 2018 | Apostolopoulou M (2018) Determinants of insulin sensitivity in obesity and recent-onset type 2 diabetes mellitus. PhD Thesis 77. | OXPHOS ET | F N NS | Homogenate Isolated mitochondria | Human | Liver |
| Torres 2018 Cell Metab | 2018 | Torres MJ, Kew KA, Ryan TE, Pennington ER, Lin CT, Buddo KA, Fix AM, Smith CA, Gilliam LA, Karvinen S, Lowe DA, Spangenburg EE, Zeczycki TN, Shaikh SR, Neufer PD (2018) 17β-estradiol directly lowers mitochondrial membrane microviscosity and improves bioenergetic function in skeletal muscle. Cell Metab 27:167-79. https://doi.org/10.1016/j.cmet.2017.10.003 | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Picard 2018 Biol Psychiatry | 2018 | Picard M, Prather AA, Puterman E, Cuillerier A, Coccia M, Aschbacher K, Burelle Y, Epel ES (2018) A mitochondrial health index sensitive to mood and caregiving stress. Biol Psychiatry 84:9-17. https://doi.org/10.1016/j.biopsych.2018.01.012 | F | Human | Blood cells | ||
| Ma 2018 Cancer Lett | 2018 | Ma Y, Temkin SM, Hawkridge AM, Guo C, Wang W, Wang XY, Fang X (2018) Fatty acid oxidation: an emerging facet of metabolic transformation in cancer. Cancer Lett 435:92-100. https://doi.org/10.1016/j.canlet.2018.08.006 | F | ||||
| Cardinale 2018 Thesis | 2018 | Cardinale DA (2018) The significance of mitochondrial respiratory function in regulating oxygen uptake and performance in humans. PhD Thesis 99. | LEAK OXPHOS | F N NS | Permeabilized tissue Isolated mitochondria | Human | Skeletal muscle |
| Picard 2018 Psychosom Med | 2018 | Picard M, McEwen BS (2018) Psychological stress and mitochondria: a systematic review. Psychosom Med 80:141-53. https://doi.org/10.1097/PSY.0000000000000545 | F | ||||
| D'Souza 2018 J Lipid Res | 2018 | D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC (2018) Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res 59:1805-17. | LEAK OXPHOS | F N S ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Mahapatra 2018 Clin Sci (Lond) | 2018 | Mahapatra G, Smith SC, Hughes TM, Wagner B, Maldjian JA, Freedman BI, Molina AJA (2018) Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes. Clin Sci (Lond) 132:2509-18. https://doi.org/10.1042/CS20180690 | LEAK OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells | Human | Nervous system Blood cells |
| Dejmek 2018 Physiol Res | 2018 | Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J (2018) Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res 67(Suppl 4):S633-S643. | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Intact cells | Human | Lung;gill Fibroblast |
| Knottnerus 2018 Rev Endocr Metab Disord | 2018 | Knottnerus SJG, Bleeker JC, Wüst RCI, Ferdinandusse S, IJlst L, Wijburg FA, Wanders RJA, Visser G, Houtkooper RH (2018) Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle. Rev Endocr Metab Disord 19:93-106. https://doi.org/10.1007/s11154-018-9448-1 | F | ||||
| Jelenik 2018 Diabetes | 2018 | Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J (2018) Insulin resistance and vulnerability to cardiac ischemia. Diabetes 67:2695-702. | LEAK OXPHOS | F N NS ROX | Permeabilized tissue Isolated mitochondria | Human Mouse | Heart |
| Fisher-Wellman 2018 Cell Rep | 2018 | Fisher-Wellman KH, Davidson MT, Narowski TM, Lin CT, Koves TR, Muoio DM (2018) Mitochondrial diagnostics: A multiplexed assay platform for comprehensive assessment of mitochondrial energy fluxes. Cell Rep 24:3593-606. | LEAK OXPHOS | F N S | Isolated mitochondria | Mouse | Heart Skeletal muscle |
| Gratl 2018 Thesis | 2018 | Gratl A (2018) High-resolution respirometry for measurement of mitochondrial function in PAD patients before and after revascularisation. PhD Thesis 69. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Bertero 2018 Nat Rev Cardiol | 2018 | Bertero E, Maack C (2018) Metabolic remodelling in heart failure. Nat Rev Cardiol 15:457-70. https://doi.org/10.1038/s41569-018-0044-6 | F | Heart | |||
| McLaughlin 2018 Biochem Biophys Res Commun | 2018 | McLaughlin KL, McClung JM, Fisher-Wellman KH (2018) Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart. Biochem Biophys Res Commun 504:742-48. | N S F | Isolated mitochondria | Mouse | Heart | |
| Hancock 2018 Elife | 2018 | Hancock M, Hafstad AD, Nabeebaccus AA, Catibog N, Logan A, Smyrnias I, Hansen SS, Lanner J, Schröder K, Murphy MP, Shah AM, Zhang M (2018) Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. Elife 7:e41044. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Mouse | Heart |
| Lu 2018 Cell Discov | 2018 | Lu Z, Wei X, Sun F, Zhang H, Gao P, Pu Y, Wang A, Chen J, Tong W, Li Q, Zhou X, Yan Z, Zheng H, Yang G, Huang Y, Liu D, Zhu Z (2018) Non-insulin determinant pathways maintain glucose homeostasis upon metabolic surgery. Cell Discov 4:58. | OXPHOS ET | F N ROX | Isolated mitochondria | Rat | Skeletal muscle Liver |
| Valentine 2018 J Gerontol A Biol Sci Med Sci | 2018 | Valentine JM, Li ME, Shoelson SE, Zhang N, Reddick RL, Musi N (2018) NFκB regulates muscle development and mitochondrial function. J Gerontol A Biol Sci Med Sci 75:647-53. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
| Konopka 2018 Aging Cell | 2018 | Konopka AR, Laurin JL, Schoenberg HM, Reid JJ, Castor WM, Wolff CA, Musci RV, Safairad OD, Linden MA, Biela LM, Bailey SM, Hamilton KL, Miller BF (2018) Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults. Aging Cell 18:e12880. | OXPHOS ET LEAK | F N NS S ROX | Permeabilized tissue | Human | Skeletal muscle |
| Park 2018 J Clin Invest | 2018 | Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ (2018) Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest 129:694-711. | OXPHOS ET LEAK | F N S | Permeabilized tissue | Mouse | Fat |
| Wilmanns 2018 Mol Metab | 2018 | Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW (2018) Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease. Mol Metab 20:102-14. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Mouse | Heart |
| Oemer 2018 Proc Nat Acad Sci U S A | 2018 | Oemer G, Lackner L, Muigg K, Krumschnabel G, Watschinger K, Sailer S, Lindner H, Gnaiger E, Wortmann SB, Werner ER, Zschocke J, Keller MA (2018) The molecular structural diversity of mitochondrial cardiolipins. Proc Nat Acad Sci U S A 115:4158-63. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Intact cells Permeabilized cells | Human | HeLa |
| Cruz 2018 Lipids Health Dis | 2018 | Cruz MM, Lopes AB, Crisma AR, de Sá RCC, Kuwabara WMT, Curi R, de Andrade PBM, Alonso-Vale MIC (2018) Palmitoleic acid (16:1n7) increases oxygen consumption, fatty acid oxidation and ATP content in white adipocytes. Lipids Health Dis 17:55. | ET | F | Intact cells | Mouse | Fat Other cell lines |
| Chen 2018 Hum Mol Genet | 2018 | Chen A, Tiosano D, Guran T, Baris HN, Bayram Y, Mory A, Shapiro-Kulnane L, Hodges CA, Coban Akdemir Z, Turan S, Jhangiani SN, van den Akker F, Hoppel CL, Salz HK, Lupski JR, Buchner DA (2018) Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency. Hum Mol Genet 27:1913-26. | OXPHOS ET | F N S DQ CIV NS | Isolated mitochondria | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
| Van Erp 2018 Sci Rep | 2018 | Van Erp AC, Rebolledo RA, Hoeksma D, Jespersen NR, Ottens PJ, Nørregaard R, Pedersen M, Laustsen C, Burgerhof JGM, Wolters JC, Ciapaite J, Bøtker HE, Leuvenink HGD, Jespersen B (2018) Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys. Sci Rep 8:4405. | OXPHOS ET | F N S NS | Isolated mitochondria | Rat | Liver Kidney |
| Hsiao 2018 Anal Biochem | 2018 | Hsiao CP, Hoppel C (2018) Analyzing mitochondrial function in human peripheral blood mononuclear cells. Anal Biochem 549:12-20. | OXPHOS ET | F N S DQ CIV NS ROX | Intact cells | Human | Blood cells |
| Szelechowski 2018 Sci Rep | 2018 | Szelechowski M, Amoedo N, Obre E, Léger C, Allard L, Bonneu M, Claverol S, Lacombe D, Oliet S, Chevallier S, Le Masson G, Rossignol R (2018) Metabolic reprogramming in amyotrophic lateral sclerosis. Sci Rep 8:3953. | LEAK ROUTINE ET | F ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
| Bryant 2018 Thesis | 2018 | Bryant HJ (2018) The role of mitochondrial uncoupling in temperature responses in Atlantic killifish, Fundulus heteroclitus. Master's Thesis p126. | LEAK OXPHOS ET | F S | Isolated mitochondria | Fishes | Nervous system Liver Fat |
| Doerrier 2018 Methods Mol Biol | 2018 | Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70. https://doi.org/10.1007/978-1-4939-7831-1_3 | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells | Human Mouse Rat Saccharomyces cerevisiae | Heart Skeletal muscle Endothelial;epithelial;mesothelial cell Blood cells HEK Platelet |
| Chicco 2018 J Biol Chem | 2018 | Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC (2018) Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem 293:6659-71. | LEAK OXPHOS ET | F N S | Permeabilized tissue | Human | Skeletal muscle |
| Fernandes-Siqueira 2018 mSphere | 2018 | Fernandes-Siqueira LO, Zeidler JD, Sousa BG, Ferreira T, Da Poian AT (2018) Anaplerotic role of glucose in the oxidation of endogenous fatty acids during Dengue virus infection. mSphere 3.pii: e00458-17. | LEAK ET | F ROX | Intact cells | Human | Liver Other cell lines |
| Bjoerndal 2018 Nutr Metab (Lond) | 2018 | Bjørndal B, Alterås EK, Lindquist C, Svardal A, Skorve J, Berge RK (2018) Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice. Nutr Metab (Lond) 15:10. | OXPHOS ET | F N ROX | Homogenate | Mouse | Liver |
| Leckey 2018 FASEB J | 2018 | Leckey JJ, Hoffman NJ, Parr EB, Devlin BL, Trewin AJ, Stepto NK, Morton JP, Burke LM, Hawley JA (2018) High dietary fat intake increases fat oxidation and reduces skeletal muscle mitochondrial respiration in trained humans. FASEB J 32:2979-91. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Boutoual 2018 Sci Rep | 2018 | Boutoual R, Meseguer S, Villarroya M, Martín-Hernández E, Errami M, Martín MA, Casado M, Armengod ME (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis. Sci Rep 8:1163. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Smenes 2018 Interact Cardiovasc Thorac Surg | 2018 | Smenes BT, Bækkerud FH, Slagsvold KH, Hassel E, Wohlwend M, Pinho M, Høydal M, Wisløff U, Rognmo Ø, Wahba A (2018) Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interact Cardiovasc Thorac Surg 27:95-101. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Heart |
| Hoffmann 2018 Sci Rep | 2018 | Hoffmann C, Höckele S, Kappler L, Hrabĕ de Angelis M, Häring HU, Weigert C (2018) The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells. Sci Rep 8:737. | OXPHOS ET | F N S NS ROX | Permeabilized cells | Human | Skeletal muscle |
| Wefers 2018 Proc Natl Acad Sci U S A | 2018 | Wefers J, van Moorsel D, Hansen J, Connell NJ, Havekes B, Hoeks J, van Marken Lichtenbelt WD, Duez H, Phielix E, Kalsbeek A, Boekschoten MV, Hooiveld GJ, Hesselink MKC, Kersten S, Staels B, Scheer FAJL, Schrauwen P (2018) Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle. Proc Natl Acad Sci U S A 115:7789-94. | OXPHOS ET | F N | Intact cells | Human | Skeletal muscle |
| Lund 2018 Acta Physiol (Oxf) | 2018 | Lund MT, Larsen S, Hansen M, Courraud J, Floyd AK, Støckel M, Helge JW, Dela F (2018) Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery. Acta Physiol (Oxf) 223:e13032. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Setz 2018 Hear Res | 2018 | Setz C, Benischke AS, Pinho Ferreira Bento AC, Brand Y, Levano S, Paech F, Leitmeyer K, Bodmer D (2018) Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti. Hear Res 361:52-65. | OXPHOS ET | F N S NS ROX | Permeabilized cells | Mouse | Other cell lines |
| Robach 2018 Scand J Med Sci Sports | 2018 | Robach P, Hansen J, Pichon A, Meinild Lundby AK, Dandanell S, Slettaløkken Falch G, Hammarström D, Pesta DH, Siebenmann C, Keiser S, Kérivel P, Whist JE, Rønnestad BR, Lundby C (2018) Hypobaric live high-train low does not improve aerobic performance more than live low-train low in cross-country skiers. Scand J Med Sci Sports 28:1636-52. | OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Cardinale 2018 Physiol Rep | 2018 | Cardinale DA, Gejl KD, Ørtenblad N, Ekblom B, Blomstrand E, Larsen FJ (2018) Reliability of maximal mitochondrial oxidative phosphorylation in permeabilized fibers from the vastus lateralis employing high-resolution respirometry. Physiol Rep 6. doi: 10.14814/phy2.13611. | LEAK OXPHOS | F N | Permeabilized tissue | Human | Skeletal muscle |
| Jelenik 2018 Mol Metab | 2018 | Jelenik T, Dille M, Müller-Lühlhoff S, Kabra DG, Zhou Z, Binsch C, Hartwig S, Lehr S, Chadt A, Peters EMJ, Kruse J, Roden M, Al-Hasani H, Castañeda TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Mouse | Skeletal muscle |
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| Martins 2018 Comp Biochem Physiol B Biochem Mol Biol | 2018 | Martins EL, Ricardo JC, de-Souza-Ferreira E, Camacho-Pereira J, Ramos-Filho D, Galina A (2018) Rapid regulation of substrate use for oxidative phosphorylation during a single session of high intensity interval or aerobic exercises in different rat skeletal muscles. Comp Biochem Physiol B Biochem Mol Biol 217:40-50. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
| Koit 2018 US Patent | 2018 | Koit A, Kaambre T (2018) Method for selecting patients responsive for cancer treatments. US Patent US20180017547A1. | OXPHOS | F N NS | Permeabilized cells | Human | |
| Thrush 2018 Int J Obes (Lond) | 2018 | Thrush AB, Antoun G, Nikpay M, Patten DA, DeVlugt C, Mauger JF, Beauchamp BL, Lau P, Reshke R, Doucet É, Imbeault P, Boushel R, Gibbings D, Hager J, Valsesia A, Slack R, Al-Dirbashi OY, Dent R, McPherson R, Harper ME (2018) Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism. Int J Obes (Lond) 42:353-62. | LEAK OXPHOS ET | F N CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Distefano 2018 J Cachexia Sarcopenia Muscle | 2018 | Distefano G, Standley RA, Zhang X, Carnero EA, Yi F, Cornnell HH, Coen PM (2018) Physical activity unveils the relationship between mitochondrial energetics, muscle quality, and physical function in older adults. J Cachexia Sarcopenia Muscle 9:279-94. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Monaco 2018 Diabetologia | 2018 | Monaco CMF, Proudfoot R, Miotto PM, Herbst EAF, MacPherson REK, Holloway GP (2018) α-linolenic acid supplementation prevents exercise-induced improvements in white adipose tissue mitochondrial bioenergetics and whole-body glucose homeostasis in obese Zucker rats. Diabetologia 61:433-44. | F N | Permeabilized tissue | Rat | Skeletal muscle Fat | |
| Allard 2018 J Clin Endocrinol Metab | 2018 | Allard NAE, Schirris TJJ, Verheggen RJ, Russel FGM, Rodenburg RJ, Smeitink JAM, Thompson PD, Hopman MTE, Timmers S (2018) Statins affect skeletal muscle performance: evidence for disturbances in energy metabolism. J Clin Endocrinol Metab 103:75-84. | OXPHOS | F N S Gp CIV NS | Permeabilized tissue | Human | Skeletal muscle |
| De Medeiros 2018 Biochim Biophys Acta | 2018 | de Medeiros WA, da Silva LA, Dall'Igna DM, Michels M, Manfredini A, Dos Santos Cardoso J, Constantino L, Scaini G, Vuolo F, Streck EL, Ritter C, Dal-Pizzol F (2018) N-acetylcysteine effects on a murine model of chronic critical limb ischemia. Biochim Biophys Acta 1864:454-63. | OXPHOS | F N NS | Rat | ||
| Kappler 2018 Thesis | 2018 | Kappler L (2018) Method development for valid high‐resolution profiling of mitochondria and Omics investigation of mitochondrial adaptions to excess energy intake and physical exercise. Dissertation p181. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Skeletal muscle Liver Other cell lines |
| Gam 2018 Acta Diabetol | 2018 | Gam CMBF, Mortensen OH, Larsen LH, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B (2018) Diabetes, myometrium, and mitochondria in pregnant women at term. Acta Diabetol 55:999-1010. | LEAK OXPHOS | F N S NS | Isolated mitochondria | Human | Genital |
| Barca 2018 Hum Mol Genet | 2018 | Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12. | LEAK ROUTINE OXPHOS ET | F N S DQ NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
| Chou 2018 Int J Cardiol | 2018 | Chou CH, Fu TC, Tsai HH, Hsu CC, Wang CH, Wang JS (2018) High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure. Int J Cardiol 274:214-20. | LEAK ROUTINE OXPHOS ET | F N S NS ROX | Intact cells Permeabilized cells | Human | Platelet Blood cells |
| Stein 2018 Cell Rep | 2018 | Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL (2018) Mitoregulin: A lncRNA-encoded microprotein that supports mitochondrial supercomplexes and respiratory efficiency. Cell Rep 23:3710-20. | LEAK OXPHOS | F N | Permeabilized tissue | Human | Heart Skeletal muscle |
| Weber 2018 Int J Mol Sci | 2018 | Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE (2018) Succinate accumulation is associated with a shift of mitochondrial respiratory control and HIF-1α upregulation in PTEN negative prostate cancer cells. Int J Mol Sci 19:2129. | ROUTINE OXPHOS ET | F N S NS Other combinations ROX | Intact cells Permeabilized cells | Human | Genital |
| Cardinale 2018 Acta Physiol (Oxf) | 2018 | Cardinale DA, Larsen FJ, Jensen-Urstad M, Rullman E, Søndergaard H, Morales-Alamo D, Ekblom B, Calbet JAL, Boushel R (2018) Muscle mass and inspired oxygen influence oxygen extraction at maximal exercise: Role of mitochondrial oxygen affinity. Acta Physiol (Oxf) 225:e13110. | OXPHOS | F N NS | Permeabilized tissue Isolated mitochondria | Human | Skeletal muscle |
| Bytautiene 2018 J Dev Orig Health Dis | 2018 | Bytautiene Prewit E, Porter C, La Rosa M, Bhattarai N, Yin H, Gamble P, Kechichian T, Sidossis LS (2018) Adipose tissue uncoupling protein 1 levels and function are increased in a mouse model of developmental obesity induced by maternal exposure to high-fat diet. J Dev Orig Health Dis 9:401-8. | LEAK | F N | Permeabilized tissue | Mouse | Fat |
| Ravasz 2018 Biochim Biophys Acta | 2018 | Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2018) Reduction of 2-methoxy-1,4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD+ supports substrate-level phosphorylation during respiratory inhibition. Biochim Biophys Acta 1859:909-24. | LEAK OXPHOS | F N DQ | Isolated mitochondria | Mouse | Liver |
| Stanford 2018 Cell Metab | 2018 | Stanford KI, Lynes MD, Takahashi H, Baer LA, Arts PJ, May FJ, Lehnig AC, Middelbeek RJW, Richard JJ, So K, Chen EY, Gao F, Narain NR, Distefano G, Shettigar VK, Hirshman MF, Ziolo MT, Kiebish MA, Tseng YH, Coen PM, Goodyear LJ (2018) 12,13-diHOME: an exercise-induced lipokine that increases skeletal muscle fatty acid uptake. Cell Metab 27:1111-20. | LEAK OXPHOS ET | F ROX | Permeabilized tissue | Human Mouse | Skeletal muscle |
| Toledo 2018 Obesity (Silver Spring) | 2018 | Toledo FGS, Dubé JJ, Goodpaster BH, Stefanovic-Racic M, Coen PM, DeLany JP (2018) Mitochondrial respiration is associated with lower energy expenditure and lower aerobic capacity in African American women. Obesity (Silver Spring) 26:903-9. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Boutoual 2018 Scientific Reports | 2018 | Boutoual, R., Meseguer, S., Villarroya, M., Martin-Hernandez, E., Errami, M., Martin, M. A., Casado, M., and Armengod, M. E. (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARgamma-UCP2-AMPK axis. Scientific reports 8, 1163 | LEAK ROUTINE OXPHOS ET | F S Gp | Permeabilized cells Intact cells | Human | Other cell lines Fibroblast |
| Lima 2018 Biochem Cell Biol | 2018 | Lima T, Silveira L (2018) A microplate assay for measuring cell death in C2C12 cells. Biochem Cell Biol 96:702-6. | LEAK ET | F | Intact cells | Mouse | Skeletal muscle Other cell lines |
| Zhang 2018 J Gerontol A Biol Sci Med Sci | 2018 | Zhang X, Trevino MB, Wang M, Gardell SJ, Ayala JE, Han X, Kelly DP, Goodpaster BH, Vega RB, Coen PM (2018) Impaired mitochondrial energetics characterize poor early recovery of muscle mass following hind limb unloading in old mice. J Gerontol A Biol Sci Med Sci 73:1313-22. | LEAK OXPHOS | F N NS | Mouse | Skeletal muscle | |
| Scheiber 2018 J Cardiovasc Transl Res | 2018 | Scheiber D, Zweck E, Jelenik T, Horn P, Albermann S, Masyuk M, Boeken U, Saeed D, Kelm M Roden M, Szendroedi J, Westenfeld R (2018) Reduced myocardial mitochondrial ROS production in mechanically unloaded hearts. J Cardiovasc Transl Res 12:107-15. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Human | Heart |
| Becker 2018 EMBO Rep | 2018 | Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid CP, Maiti P, Trifunovic A (2018) CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep 19. pii: e45126. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Mouse | Liver Fat |
| Komlodi 2018 Methods Mol Biol | 2018 | Komlodi T, Sobotka O, Krumschnabel G, Bezuidenhout N, Hiller E, Doerrier C, Gnaiger E (2018) Comparison of mitochondrial incubation media for measurement of respiration and hydrogen peroxide production. Methods Mol Biol 1782:137-55. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Permeabilized tissue | Human Mouse | Skeletal muscle HEK |
| Chung 2018 J Exp Biol | 2018 | Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458. | LEAK OXPHOS ET | F N S CIV NS ROX | Isolated mitochondria | Fishes | Liver |
| Rajkumar 2018 Metabolism | 2018 | Rajkumar A, Liaghati A, Chan J, Lamothe G, Dent R, Doucet É, Rabasa-Lhoret R, Prud'homme D, Harper ME, Tesson F (2018) ACSL5 genotype influence on fatty acid metabolism: a cellular, tissue, and whole-body study. Metabolism 83:271-9. | OXPHOS ET | F N CIV NS | Permeabilized cells | Human Mouse | Skeletal muscle Other cell lines |
| Cree-Green 2018 Diabetes | 2018 | Cree-Green M, Scalzo RL, Harrall K, Newcomer BR, Schauer IE, Huebschmann AG, McMillin S, Brown MS, Orlicky D, Knaub L, Nadeau KJ, Mcclatchey PM, Bauer TA, Regensteiner JG, Reusch JEB (2018) Supplemental oxygen improves in-vivo mitochondrial oxidative phosphorylation flux in sedentary obese adults with type 2 diabetes. Diabetes 67:1369-79. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Svensson 2017 Acta Physiol (Oxf) | 2017 | Svensson K, LaBarge SA, Martins VF, Schenk S (2017) Temporal overexpression of SIRT1 in skeletal muscle of adult mice does not improve insulin sensitivity or markers of mitochondrial biogenesis. Acta Physiol (Oxf) 221:193-203. | OXPHOS ET LEAK | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Trewin 2017 PLOS ONE | 2017 | Trewin AJ, Levinger I, Parker L, Shaw CS, Serpiello FR, Anderson MJ, McConell GK, Hare DL, Stepto NK (2017) Acute exercise alters skeletal muscle mitochondrial respiration and H2O2 emission in response to hyperinsulinemic-euglycemic clamp in middle-aged obese men. PLOS ONE 12:e0188421. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| De Carvalho 2017 Toxicol Research | 2017 | de Carvalho NR, Rodrigues NR, Macedo GE, Boligon AA, de Campos MM, Posser T, Cunha FAB, Coutinho HD, Klamt F, Bristot IJ, Merritt TJS, Franco JL (2017) Eugenia uniflora leaves essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation. Toxicol Research 6:526-34 . | LEAK OXPHOS ET | F N NS ROX S | Isolated mitochondria | Drosophila | |
| Mueller 2017 Orphanet J Rare Dis | 2017 | Mueller SM, Gehrig SM, Petersen JA, Frese S, Mihaylova V, Ligon-Auer M, Khmara N, Nuoffer JM, Schaller A, Lundby C, Toigo M, Jung HH (2017) Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients. Orphanet J Rare Dis 12:184. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Newsom 2017 Am J Physiol Endocrinol Metab | 2017 | Newsom SA, Miller BF, Hamilton KL, Ehrlicher SE, Stierwalt HD, Robinson MM (2017) Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with high fat feeding regardless of insulin sensitizing treatment. Am J Physiol Endocrinol Metab 313:552-62. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
| Categories of SUIT protocols | 2017 | Gnaiger E (2017) Categories of SUIT protocols and ETS pathway control states. MiPNet 2017-03-12; original 2016-03-20; edited 2016-08-21. | F N S Gp CIV NS Other combinations ROX | ||||
| Jelenik 2017 Diabetes | 2017 | Jelenik T, Kaul K, Séquaris G, Flögel U, Phielix E, Kotzka J, Knebel B, Fahlbusch P, Hörbelt T, Lehr S, Reinbeck AL, Müller-Wieland D, Esposito I, Shulman GI, Szendroedi J, Roden M (2017) Mechanisms of insulin resistance in primary and secondary nonalcoholic fatty liver. Diabetes 66:2241-53. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle Liver |
| Bohanon 2017 Shock | 2017 | Bohanon FJ, Lopez ON, Herndon DN, Wang X, Bhattarai N, Ayadi AE, Prasai A, Jay JW, Rojas-Khalil Y, Toliver-Kinsky TE, Finnerty CC, Radhakrishnan RS, Porter C (2017) Burn trauma acutely increases the respiratory capacity and function of liver mitochondria. Shock 49:466-73. | LEAK OXPHOS ET | F N ROX | Intact cells | Mouse | Liver |
| Van Schaardenburgh 2017 J Transl Med | 2017 | van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJR (2017) Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function. J Transl Med 15:130. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Holland 2017 Placenta | 2017 | Holland OJ, Hickey AJR, Alvsaker A, Moran S, Hedges C, Chamley LW, Perkins AV (2017) Changes in mitochondrial respiration in the human placenta over gestation. Placenta 57:102-12. | LEAK ROUTINE OXPHOS | F N CIV NS ROX | Permeabilized cells Intact cells | Genital | |
| Asping 2017 Eur J Clin Pharmacol | 2017 | Asping M, Stride N, Søgaard D, Dohlmann TL, Helge JW, Dela F, Larsen S (2017) The effects of 2 weeks of statin treatment on mitochondrial respiratory capacity in middle-aged males: the LIFESTAT study. Eur J Clin Pharmacol 73:679-87. | LEAK ET | F N S CIV NS ROX | Permeabilized tissue | Human | |
| Permer 2017 Bachelor Thesis | 2017 | Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Intact cells | Human | Other cell lines HEK |
| Heim 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | Heim AB, Chung D, Florant GL, Chicco AJ (2017) Tissue-specific seasonal changes in mitochondrial function of a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 313:R180-90. | LEAK OXPHOS | F NS | Isolated mitochondria | Other mammals | Heart Skeletal muscle Liver Fat |
| Merz 2017 Intensive Care Med Exp | 2017 | Merz T, Vogt JA, Wachter U, Calzia E, Szabo C, Wang R, Radermacher P, McCook O (2017) Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock. Intensive Care Med Exp 5:30. | LEAK OXPHOS ET | F N S NS ROX | Homogenate | Mouse | Liver |
| Emmett 2017 Nature | 2017 | Emmett MJ, Lim HW, Jager J, Richter HJ, Adlanmerini M, Peed LC, Briggs ER, Steger DJ, Ma T, Sims CA, Baur JA, Pei L, Won KJ, Seale P, Gerhart-Hines Z, Lazar MA (2017) Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge. Nature 546:544-8. | LEAK OXPHOS | F N S CIV ROX | Homogenate | Mouse | Fat |
| Zeidler 2017 J Biol Chem | 2017 | Zeidler JD, Fernandes-Siqueira LO, Carvalho AS, Cararo-Lopes E, Dias MH, Ketzer LA, Galina A, Da Poian AT (2017) Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria. J Biol Chem 292:14176-87. | LEAK ROUTINE ET | F N ROX | Intact cells | Mouse | |
| Sobotka 2017 Thesis | 2017 | Sobotka O (2017) Pharmacological and metabolic influence on liver mitochondrial functions. PhD Thesis p127. | LEAK OXPHOS ET | F N NS | Homogenate Isolated mitochondria Intact cells | Mouse Rat | Liver |
| Horscroft 2017 Proc Natl Acad Sci U S A | 2017 | Horscroft JA, Kotwica AO, Laner V, West JA, Hennis PJ, Levett DZH, Howard DJ, Fernandez BO, Burgess SL, Ament Z, Gilbert-Kawai ET, Vercueil A, Landis BD, Mitchell K, Mythen MG, Branco C, Johnson RS, Feelisch M, Montgomery HE, Griffin JL, Grocott MPW, Gnaiger E, Martin DS, Murray AJ (2017) Metabolic basis to Sherpa altitude adaptation. Proc Natl Acad Sci U S A 114:6382–7. https://doi.org/10.1073/pnas.1700527114 | LEAK OXPHOS ET | F N S NS Other combinations | Permeabilized tissue | Human | Skeletal muscle |
| Miller 2017 PLOS ONE | 2017 | Miller B, Hamilton K, Boushel R, Williamson K, Laner V, Gnaiger E, Davis M (2017) Mitochondrial respiration in highly aerobic canines in the non-raced state and after a 1600-km sled dog race. PLOS ONE 12:e0174874. | OXPHOS ET LEAK | F N S NS ROX | Permeabilized tissue | Dog | Skeletal muscle |
| Makrecka-Kuka 2017 Toxicol Lett | 2017 | Makrecka-Kuka M, Volska K, Antone U, Vilskersts R, Grinberga S, Bandere D, Liepinsh E, Dambrova M (2017) Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria. Toxicol Lett 267:32-8. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Heart |
| Porras 2017 Stem Cells | 2017 | Porras DP, Abbaszadeh M, Bhattacharya D, D'Souza NC, Edjiu NR, Perry CG, Scimè A (2017) p107 determines a metabolic checkpoint required for adipocyte lineage fates. Stem Cells 35:1378-91. | OXPHOS LEAK | F N | Intact cells | Mouse | Fat Fibroblast |
| Edgett 2017 Thesis | 2017 | Edgett B (2017) Regulation of SIRT1, SIRT3, PGC-1α, and LRP130 in response to energetic stress in human skeletal muscle. Doctoral Dissertation p145. | LEAK OXPHOS | F N NS S | Permeabilized tissue | Human | Skeletal muscle |
| Nabben 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | Nabben M, Schmitz JP, Ciapaite J, Le Clercq CM, van Riel NA, Haak HR, Nicolay K, de Coo IF, Smeets HJ, Praet SF, van Loon LJ, Prompers JJ (2017) Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in mitochondrial myopathy patients. Am J Physiol Regul Integr Comp Physiol 312:689-701. | LEAK OXPHOS ET | F N S | Permeabilized tissue | Human | Skeletal muscle |
| McFarlane 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | McFarlane SV, Mathers KE, Staples JF (2017) Reversible temperature-dependent differences in brown adipose tissue respiration during torpor in a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 312:R434-42. | LEAK ROUTINE OXPHOS | F N | Isolated mitochondria Intact cells | Other mammals | Fat |
| Jespersen 2017 J Physiol | 2017 | Jespersen NR, Yokota T, Støttrup NB, Bergdahl A, Paelestik KB, Povlsen JA, Dela F, Bøtker HE (2017) Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion. J Physiol 595:3765-80. | LEAK OXPHOS | F N NS ROX S | Permeabilized tissue | Rat | Heart |
| Van Schaardenburgh 2017 J Vasc Surg | 2017 | Van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson E (2017) Calf raise exercise increases walking performance in patients with intermittent claudication. J Vasc Surg 65:1473-82. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Chavanelle 2017 Sci Rep | 2017 | Chavanelle V, Boisseau N, Otero YF, Combaret L, Dardevet D, Montaurier C, Delcros G, Peltier SL, Sirvent P (2017) Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice. Sci Rep 7:204. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Desprat 2017 Comp Biochem Physiol A Mol Integr Physiol | 2017 | Desprat JL, Teulier L, Puijalon S, Dumet A, Romestaing C, Tattersall GJ, Lengagne T, Mondy N (2017) Doping for sex: Bad for mitochondrial performances? Case of testosterone supplemented Hyla arborea during the courtship period. Comp Biochem Physiol A Mol Integr Physiol 209:74-83. | OXPHOS ET LEAK | F NS | Permeabilized tissue | Amphibians | Skeletal muscle |
| Liu 2017 Physiol Rep | 2017 | Liu A, Philip J, Vinnakota KC, Van den Bergh F, Tabima DM, Hacker T, Beard DA, Chesler NC (2017) Estrogen maintains mitochondrial content and function in the right ventricle of rats with pulmonary hypertension. Physiol Rep 5:e13157. | OXPHOS LEAK | F N | Isolated mitochondria | Rat | Heart |
| Wolff 2017 Thesis | 2017 | Wolff C (2017) Impact of lipid metabolism on skeletal muscle mitochondrial function in type 2 diabetes mellitus patients. Dissertation p68. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Horse Human | Skeletal muscle |
| Joergensen 2017 Physiol Rep | 2017 | Jørgensen W, Rud KA, Mortensen OH, Frandsen L, Grunnet N, Quistorff B (2017) Your mitochondria are what you eat: a high-fat or a high-sucrose diet eliminates metabolic flexibility in isolated mitochondria from rat skeletal muscle. Physiol Rep 5. pii: e13207. | LEAK OXPHOS | F N NS | Isolated mitochondria | Rat | Skeletal muscle |
| Schoenfeld 2017 Neurochem Int | 2017 | Schönfeld P, Reiser G (2017) Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration. Neurochem Int 109:68-77. | OXPHOS LEAK | F N | Isolated mitochondria | Rat | Nervous system Liver |
| Lalia 2017 Aging (Albany NY) | 2017 | Lalia AZ, Dasari S, Robinson MM, Abid H, Morse DM, Klaus KA, Lanza IR (2017) Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults. Aging (Albany NY) 9:1096-1129. | OXPHOS LEAK ET | F N NS ROX S | Isolated mitochondria | Human | Skeletal muscle |
| Anderson 2017 Cell Metab | 2017 | Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD (2017) SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion. Cell Metab 25:838-55. | OXPHOS LEAK | F N NS Other combinations | Isolated mitochondria | Mouse | Heart Liver |
| Buck 2017 PLOS ONE | 2017 | Buck E, Zügel M, Schumann U, Merz T, Gumpp AM, Witting A, Steinacker JM, Landwehrmeyer GB, Weydt P, Calzia E, Lindenberg KS (2017) High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function. PLOS ONE 12:e0175248. | LEAK OXPHOS ET | F N S NS ROX | Homogenate | Human Mouse | Heart Skeletal muscle Nervous system Liver |
| Kyhl 2017 Peptides | 2017 | Kyhl K, Lønborg J, Hartmann B, Kissow H, Poulsen SS, Ali HE, Kjær A, Dela F, Engstrøm T, Treiman M (2017) Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction. Peptides 93:1-12. | OXPHOS LEAK | F N S NS ROX | Permeabilized tissue | Rat | Heart |
| Warren 2017 J Nutr Metab | 2017 | Warren JL, Gower BA, Hunter GR, Windham ST, Moellering DR, Fisher G (2017) Associations of mitochondrial fatty acid oxidation with body fat in premenopausal women. J Nutr Metab 2017:7832057. | LEAK OXPHOS | F N | Permeabilized tissue | Human | Skeletal muscle |
| Nelskylae 2017 Resuscitation | 2017 | Nelskylä A, Nurmi J, Jousi M, Schramko A, Mervaala E, Ristagno G, Skrifvars MB (2017) The effect of 50% compared to 100% inspired oxygen fraction on brain oxygenation and post cardiac arrest mitochondrial function in experimental cardiac arrest. Resuscitation 116:1-7. | OXPHOS ET | F N S NS | Homogenate | Pig | Heart |
| Wetzel 2017 Thesis | 2017 | Wetzel MD (2017) Mechanism of metformin action in dermal fibroblasts. PhD Thesis 125. | LEAK OXPHOS | F N NS ROX | Intact cells | Human | Fibroblast |
| Warren 2017 Metabolism | 2017 | Warren JL, Bulur S, Ovalle F, Windham ST, Gower BA, Fisher G (2017) Effects of acute hyperinsulinemia on skeletal muscle mitochondrial function, reactive oxygen species production, and metabolism in premenopausal women. Metabolism 77:1-12. | LEAK OXPHOS | F N NS | Permeabilized tissue | Human | Skeletal muscle |
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| Rontoyanni 2017 Shock | 2017 | Rontoyanni VG, Malagaris I, Herndon DN, Rivas E, Capek KD, Delgadillo AD, Bhattarai N, Elizondo A, Voigt CD, Finnerty CC, Suman OE, Porter C (2017) Skeletal muscle mitochondrial function is determined by burn severity, sex and sepsis, and is associated with glucose metabolism and functional capacity in burned children. Shock 50:141-48. | LEAK OXPHOS | F N NS | Permeabilized tissue | Human | Skeletal muscle |
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| Most 2017 Eur J Clin Nutr | 2017 | Most J, Penders J, Lucchesi M, Goossens GH, Blaak EE (2017) Gut microbiota composition in relation to the metabolic response to 12-week combined polyphenol supplementation in overweight men and women. Eur J Clin Nutr 71:1040-5. | OXPHOS | F | Permeabilized tissue | Human | Skeletal muscle |
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| Darrell 2017 US Patent | 2017 | Neufer PD, Anderson EJ, Szeto HH (2017) Methods for preventing or treating insulin resistance. US Patent US20170100450 A1. | LEAK OXPHOS | F N S ROX | Permeabilized tissue | Human Rat | Skeletal muscle |
| Chung 2017 Sci Rep | 2017 | Chung DJ, Morrison PR, Bryant HJ, Jung E, Brauner CJ, Schulte PM (2017) Intraspecific variation and plasticity in mitochondrial oxygen binding affinity as a response to environmental temperature. Sci Rep 7:16238. | OXPHOS | F N NS | Isolated mitochondria | Fishes | Liver |
| Galambo 2017 Thesis | 2017 | Galambo D (2017) The effect of cardiolipin on vascular smooth muscle cell dedifferentiation, function, and mitochondrial respiration. Master's Thesis p.90. | LEAK OXPHOS | F N CIV NS ROX | Permeabilized tissue | Mouse | Endothelial;epithelial;mesothelial cell |
| Goedecke 2017 JMIR Res Protoc | 2017 | Goedecke JH, Mendham AE, Clamp L, Nono Nankam PA, Fortuin-de Smidt MC, Phiri L, Micklesfield LK, Keswell D, Woudberg NJ, Lecour S, Alhamud A, Kaba M, Lutomia FM, van Jaarsveld PJ, de Villiers A, Kahn SE, Chorell E, Hauksson J, Olsson T (2017) An exercise intervention to unravel the mechanisms underlying insulin resistance in a cohort of black South African women: Protocol for a randomized controlled trial. JMIR Res Protoc 03/10/2017:9098. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle Fat |
| Dent 2017 Mol Metab | 2017 | Dent JR, Martins VF, Svensson K, LaBarge SA, Schlenk NC, Esparza MC, Buckner EH, Meyer GA, Hamilton DL, Schenk S, Philp A (2017) Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation. Mol Metab 6:1574-84. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
| Wollenman 2017 PLOS ONE | 2017 | Wollenman LC, Vander Ploeg MR, Miller ML, Zhang Y, Bazil JN (2017) The effect of respiration buffer composition on mitochondrial metabolism and function. PLOS ONE 12:e0187523. | LEAK OXPHOS ET | F N S NS | Isolated mitochondria | Guinea pig | Heart Liver |
| Zholobenko 2017 PLOS ONE | 2017 | Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691. | LEAK OXPHOS ET ROUTINE | F N S NS ROX | Permeabilized cells Intact cells | Rat | Heart |
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| Da Silva 2017 Thesis | 2017 | da Silva LA (2017) Efeito do tratamento com N-acetilcisteína sobre dinâmica mitocondrial em modelo animal de isquemia crônica de membros inferiores. Dissertation p54. | OXPHOS | F N NS | Rat | Skeletal muscle | |
| Dechandt 2017 J Bioenerg Biomembr | 2017 | Dechandt CRP, Zuccolotto-Dos-Reis FH, Teodoro BG, Fernandes AMAP, Eberlin MN, Kettelhut IC, Curti C, Alberici LC (2017) Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr 49:399-411. | LEAK ROUTINE ET | F N ROX | Permeabilized cells Intact cells | Rat | Liver |
| Scheede-Bergdahl 2017 Can J Physiol Pharmacol | 2017 | Scheede-Bergdahl C, Bergdahl A (2017) Adaptation of mitochondrial expression and ATP production in dedifferentiating vascular smooth muscle cells. Can J Physiol Pharmacol 95:1473-9. | LEAK OXPHOS | F N CIV NS ROX | Permeabilized tissue | Mouse | Endothelial;epithelial;mesothelial cell |
| Litt 2017 Thesis | 2017 | Litt MJ (2017) Identification and characterization of a cardiomyopathy syndrome resulting from loss of the melanocortin 4 receptor. Dissertation p172. | OXPHOS ET | F N NS | Permeabilized tissue | Mouse | Heart |
| Tueller 2017 Biochem Biophys Res Commun | 2017 | Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72. | LEAK ROUTINE OXPHOS | F N NS ROX | Permeabilized cells Intact cells | Skeletal muscle | |
| Lou 2017 Physiol Rep | 2017 | Lou PH, Lucchinetti E, Scott KY, Huang Y, Gandhi M, Hersberger M, Clanachan AS, Lemieux H, Zaugg M (2017) Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats. Physiol Rep 5 pii: e13388. | LEAK OXPHOS | F N CIV NS | Rat | Heart | |
| Yu 2017 Free Radic Biol Med | 2017 | Yu Y, Wang L, Delguste F, Durand A, Guilbaud A, Rousselin C, Schmidt AM, Tessier F, Boulanger E, Neviere R (2017) Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway. Free Radic Biol Med 112:397-410. | LEAK OXPHOS | F N CIV ROX | Permeabilized tissue | Mouse | Heart |
| Jang 2017 Clin Toxicol (Phila) | 2017 | Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84. | LEAK ROUTINE OXPHOS ET | F S CIV NS ROX | Intact cells | Blood cells | |
| Kenny 2017 Diabetologia | 2017 | Kenny HC, Rudwill F, Breen L, Salanova M, Blottner D, Heise T, Heer M, Blanc S, O'Gorman DJ (2017) Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance. Diabetologia 60:1491-501. | LEAK OXPHOS ET | N S CIV NS F | Permeabilized tissue | Human | Skeletal muscle |
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| Sadhukhan 2016 Proc Natl Acad Sci U S A | 2016 | Sadhukhan S, Liu X, Ryu D, Nelson OD, Stupinski JA, Li Z, Chen W, Zhang S, Weiss RS, Locasale JW, Auwerx J, Lin H (2016) Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function. Proc Natl Acad Sci U S A 113:4320-5. | LEAK OXPHOS | F N | Permeabilized tissue | Mouse | Heart |
| Gehrig 2016 Orphanet J Rare Dis | 2016 | Gehrig SM, Mihaylova V, Frese S, Mueller SM, Ligon-Auer M, Spengler CM, Petersen JA, Lundby C, Jung HH (2016) Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopath. Orphanet J Rare Dis 11:105. | LEAK OXPHOS | F N S CIV NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
| Moon 2016 J Biol Chem | 2016 | Moon SH, Mancuso DJ, Sims HF, Liu X, Nguyen AL, Yang K, Guan S, Dilthey BG, Jenkins CM, Weinheimer CJ, Kovacs A, Abendschein D, Gross RW (2016) Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size. J Biol Chem 291:19687-700. | LEAK OXPHOS | F N S NS Other combinations ROX | Isolated mitochondria | Mouse | Heart |
| Teulier 2016 Proc Biol Sci | 2016 | Teulier L, Weber JM, Crevier J, Darveau CA (2016) Proline as a fuel for insect flight: enhancing carbohydrate oxidation in hymenopterans. Proc Biol Sci 283: 20160333. | OXPHOS | F N S Gp NS Other combinations ROX | Permeabilized tissue | Hexapods | Skeletal muscle |
| Oliveira 2016 PLOS ONE | 2016 | Oliveira MP, Correa Soares JB, Oliveira MF (2016) Sexual preferences in nutrient utilization regulate oxygen consumption and reactive oxygen species generation in Schistosoma mansoni: potential implications for parasite redox biology. PLOS ONE 11:e0158429. | LEAK ROUTINE | F ROX | Intact organism | Other invertebrates | |
| Schoenenberger 2016 Cancer Res | 2016 | Schönenberger D, Harlander S, Rajski M, Jacobs RA, Lundby AK, Adlesic M, Hejhal T, Wild PJ, Lundby C, Frew IJ (2016) Formation of renal cysts and tumors in Vhl/Trp53-deficient mice requires HIF1α and HIF2α. Cancer Res 76:2025-36. | OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Nervous system |
| Christensen 2016 J Appl Physiol (1985) | 2016 | Christensen PM, Jacobs RA, Bonne T, Flück D, Bangsbo J, Lundby C (2016) A short period of high-intensity interval training improves skeletal muscle mitochondrial function and pulmonary oxygen uptake kinetics. J Appl Physiol (1985) 120:1319-27. | LEAK OXPHOS ET | F N S CIV NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
| Ojuka 2016 Am J Physiol Endocrinol Metab | 2016 | Ojuka E, Andrew B, Bezuidenhout N, George S, Maarman G, Madlala HP, Mendham A, Osiki PO (2016) Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. Am J Physiol Endocrinol Metab 310:E715-23. https://doi.org/10.1152/ajpendo.00475.2015 | LEAK OXPHOS ET | F | Permeabilized tissue Isolated mitochondria | Human Mouse Rat | Skeletal muscle Liver |
| Gilliam 2016 Am J Physiol Endocrinol Metab | 2016 | Gilliam LA, Lark DS, Reese LR, Torres MJ, Ryan TE, Lin CT, Cathey BL, Neufer PD (2016) Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction. Am J Physiol Endocrinol Metab 311:E293-301. | LEAK OXPHOS | F N NS Other combinations | Permeabilized tissue | Mouse | Skeletal muscle |
| Edgett 2016 Exp Physiol | 2016 | Edgett BA, Hughes MC, Matusiak JB, Perry CG, Simpson CA, Gurd BJ (2016) SIRT3 gene expression but not SIRT3 subcellular localization is altered in response to fasting and exercise in human skeletal muscle. Exp Physiol 101:1101-13. | OXPHOS | F N S NS | Permeabilized tissue | Human | Skeletal muscle |
| Jiroutkova 2016 JPEN J Parenter Enteral Nutr | 2016 | Jiroutková K, Krajčová A, Žiak J, Fric M, Gojda J, Džupa V, Kalous M, Tůmová J, Trnka J, Duška F (2016) Mitochondrial function in an in vitro model of skeletal muscle of patients with protracted critical illness and intensive care unit-acquired weakness. JPEN J Parenter Enteral Nutr 41:1213-21. | LEAK ET | F ROX | Human | Skeletal muscle Other cell lines | |
| Most 2016 Am J Clin Nutr | 2016 | Most J, Timmers S, Warnke I, Jocken JW, van Boekschoten M, de Groot P, Bendik I, Schrauwen P, Goossens GH, Blaak EE (2016) Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial. Am J Clin Nutr 104:215-27. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Van Zutphen 2016 J Hepatol | 2016 | van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, Allgayer de Moraes R, Zhang L, Wolters JC, Bischoff R, Wanders RJA, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH (2016) Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction. J Hepatol 65:1198-1208. | LEAK OXPHOS ET | F N NS Other combinations | Isolated mitochondria | Rat | Liver |
| Heinonen 2016 Hum Exp Toxicol | 2016 | Heinonen JA, Schramko AA, Skrifvars MB, Litonius E, Backman JT, Mervaala E, Rosenberg PH (2016) The effects of intravenous lipid emulsion on hemodynamic recovery and myocardial cell mitochondrial function after bupivacaine toxicity in anesthetized pigs. Hum Exp Toxicol 36:365-75. | LEAK OXPHOS ET | F N S NS | Homogenate | Pig | Heart |
| Assmann 2016 Cell Rep | 2016 | Assmann N, Dettmer K, Simbuerger JM, Broeker C, Nuernberger N, Renner K, Courtneidge H, Klootwijk ED, Duerkop A, Hall A, Kleta R, Oefner PJ, Reichold M, Reinders J (2016) Renal fanconi syndrome is caused by a mistargeting-based mitochondriopathy. Cell Rep 15:1423-9. | LEAK OXPHOS ET | F N S NS Other combinations ROX | Intact cells | Pig | Kidney Other cell lines |
| Schoenfeld 2016 J Cereb Blood Flow Metab | 2016 | Schönfeld P, Reiser G (2016) Inhibition of b-oxidation is not a valid therapeutic tool for reducing oxidative stress in conditions of neurodegeneration. J Cereb Blood Flow Metab 37:848-54. | OXPHOS | F Other combinations | Isolated mitochondria | Rat | Nervous system |
| Nsiah-Sefaa 2016 Biosci Rep | 2016 | Nsiah-Sefaa A, McKenzie M (2016) Combined defects in oxidative phosphorylation and fatty acid β-oxidation in mitochondrial disease. Biosci Rep 36:e00313. https://doi.org/10.1042/BSR20150295 | F | ||||
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| Osiki 2016 FASEB J | 2016 | Osiki PO, Ojuka E, Marmaan G (2016) An investigation of the suitability of using octanoylcarnitine together with malate as a substrate combination for assessing Beta-oxidation using High Resolution Respirometry. FASEB J 30: 1015.12 . | LEAK OXPHOS ET | F | Permeabilized tissue | Rat | Skeletal muscle |
| Zabielski 2016 Diabetes | 2016 | Zabielski P, Lanza IR, Gopala S, Holtz Heppelmann CJ, Bergen HR 3rd, Dasari S, Nair KS (2016) Altered skeletal muscle mitochondrial proteome as the basis of disruption of mitochondrial function in diabetic mice. Diabetes 65:561-73. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized cells | Mouse | Skeletal muscle |
| Schoepf 2016 FEBS J | 2016 | Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells. https://doi.org/10.1111/febs.13733 | LEAK OXPHOS ET | F N S NS Other combinations ROX | Permeabilized cells Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell Genital Other cell lines Fibroblast |
| Hamilton 2016 Am J Physiol Heart Circ Physiol | 2016 | Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80. | LEAK OXPHOS | F N S NS Other combinations ROX | Permeabilized tissue Isolated mitochondria | Mouse | Heart |
| Reijne 2016 PLOS ONE | 2016 | Reijne AC, Ciapaite J, van Dijk TH, Havinga R, van der Zee EA, Groen AK, Reijngoud DJ, Bakker BM, van Dijk G (2016) Whole-body vibration partially reverses aging-induced increases in visceral adiposity and hepatic lipid storage in mice. PLOS ONE 11:e0149419. | LEAK OXPHOS | F N Other combinations | Isolated mitochondria | Mouse | Skeletal muscle Liver |
| Sparks 2016 Diabetologia | 2016 | Sparks LM, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen-Kornips E, Jörgensen JA, Nascimento EB, Hesselink MK, Schrauwen P, Hoeks J (2016) ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia 59:1030-9. | LEAK OXPHOS ET | F N NS Other combinations | Permeabilized tissue Isolated mitochondria | Human Mouse Rat | Skeletal muscle Other cell lines |
| Gemmink 2016 Diabetologia | 2016 | Gemmink A, Bosma M, Kuijpers HJ, Hoeks J, Schaart G, van Zandvoort MA, Schrauwen P, Hesselink MK (2016) Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans. Diabetologia 59:1040-8. | OXPHOS ET | F NS Other combinations | Permeabilized tissue | Human | Skeletal muscle |
| Lashbrook 2016 Thesis | 2016 | Lashbrook M (2016) Functional responses of cardiac and skeletal muscle mitochondria to short-term obesity: are all obesities the same? Master's Thesis 63pp. | LEAK OXPHOS | F N NS | Permeabilized tissue Isolated mitochondria | Mouse Other mammals | Heart Skeletal muscle |
| Newell 2016 Physiol Entomol | 2016 | Newell C, Kane CL, Kane DC (2016) Mitochondrial substrate specificity in beetle flight muscle: assessing respiratory oxygen flux in small samples from Dermestes maculatus and Tenebrio molitor. Physiol Entomol p7. | OXPHOS | F N Gp Other combinations | Permeabilized tissue | Hexapods | Skeletal muscle |
| Bernardo 2015 J Nutr Biochem | 2016 | Bernardo AF, Cortez E, Neves FA, Vieira AKG, Soares V, Rodrigues-Cunha AC, Andrade DC, Thole AA, Gabriel-Costa D, Brum PC, Moura AS, Garcia-Souza EP (2015) Overnutrition during lactation leads to impairment in insulin signaling, upregulation of GLUT1 and increased mitochondrial carbohydrate oxidation in heart of weaned mice. J Nutr Biochem 29:124-32. | LEAK OXPHOS | F N NS | Permeabilized tissue | Mouse | Heart |
| Jacobs 2016 J Physiol | 2016 | Jacobs RA, Lundby AM, Fenk S, Gehrig S, Siebenmann C, Flück D, Kirk N, Hilty MP, Lundby C (2016) Twenty-eight days of exposure to 3,454 m increases mitochondrial volume density in human skeletal muscle. J Physiol 594:1151-66. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Houten 2016 Annu Rev Physiol | 2016 | Houten SM, Violante S, Ventura FV, Wanders RJ (2016) The biochemistry and physiology of mitochondrial fatty acid β-oxidation and its genetic disorders. Annu Rev Physiol 78:23-44. doi: 10.1146/annurev-physiol-021115-105045 | F | ||||
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| Pambianco 2016 Cell Rep | 2016 | Pambianco S, Giovarelli M, Perrotta C, Zecchini S, Cervia D3, Di Renzo I, Moscheni C, Ripolone M, Violano R, Moggio M, Bassi MT, Puri PL, Latella L, Clementi E, De Palma C (2016) Reversal of defective mitochondrial biogenesis in limb-girdle muscular dystrophy 2D by independent modulation of histone and PGC-1α acetylation. Cell Rep 17:3010-23. | LEAK OXPHOS | F N S NS ROX | Permeabilized cells Isolated mitochondria Permeabilized tissue | Mouse | Skeletal muscle |
| Scott 2016 Thesis | 2016 | Scott KY (2016) Evaluation of cardiac mitochondrial function in the fructose-fed rat. Master's Thesis p98. | LEAK OXPHOS ET | F N S CIV ROX | Isolated mitochondria | Rat | Heart |
| Timmers 2016 Diabetes Care | 2016 | Timmers S, de Ligt M, Phielix E, van de Weijer T, Hansen J, Moonen-Kornips E, Schaart G, Kunz I, Hesselink MK, Schrauwen-Hinderling VB, Schrauwen P (2016) Resveratrol as add-on therapy in subjects with well-controlled type 2 diabetes: a randomized controlled trial. Diabetes Care 39:2211-17. | LEAK ET OXPHOS | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Van Eunen 2016 BMC Biol | 2016 | van Eunen K, Volker-Touw CM, Gerding A, Bleeker A, Wolters JC, van Rijt WJ, Martines AM, Niezen-Koning KE, Heiner RM, Permentier H, Groen AK, Reijngoud DJ, Derks TG, Bakker BM (2016) Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders. BMC Biol 14:107. | ET | F N | Isolated mitochondria | Mouse | Liver |
| Williams 2016 Diabetes | 2016 | Williams AS, Trefts E, Lantier L, Grueter C, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH (2016) Integrin-linked kinase is necessary for the development of diet-induced hepatic insulin resistance. Diabetes 66:325-34. | OXPHOS LEAK | F N | Isolated mitochondria | Mouse | Liver |
| LaBarge 2016 FASEB J | 2016 | LaBarge SA, Migdal CW, Buckner EH, Okuno H, Gertsman I, Stocks B, Barshop BA, Nalbandian SR, Philp A, McCurdy CE, Schenk S (2016) p300 is not required for skeletal muscle metabolic adaptation to endurance exercise training. FASEB J 30:1623-33. | LEAK OXPHOS ET | F N NS ROX S Other combinations | Permeabilized tissue | Mouse | Skeletal muscle |
| Kancirova 2016 Physiol Res | 2016 | Kancirová I, Jašová M, Muráriková M, Sumbalová Z, Uličná O, Ravingerová T, Waczulíková I, Ziegelhöffer A, Ferko M (2016) Cardioprotection induced by remote ischemic preconditioning preserves the mitochondrial respiratory function in acute diabetic myocardium. Physiol Res 65:S611-19. | LEAK OXPHOS | F N | Isolated mitochondria | Rat | Heart |
| Chorner 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Chorner Z, Barbeau PA, Castellani L, Wright DC, Chabowski A, Holloway GP (2016) Dietary α-linolenic acid supplementation alters skeletal muscle plasma membrane lipid composition, sarcolemmal FAT/CD36 abundance, and palmitate transport rates. Am J Physiol Regul Integr Comp Physiol 311:R1234-42. | LEAK OXPHOS | F N NS | Isolated mitochondria | Rat | Skeletal muscle |
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| Talati 2016 Am J Respir Crit Care Med | 2016 | Talati MH, Brittain EL, Fessel JP, Penner N, Atkinson J, Funke M, Grueter C, Jerome WG, Freeman M, Newman JH, West J, Hemnes AR (2016) Mechanisms of lipid accumulation in the bone morphogenetic protein receptor type 2 mutant right ventricle. Am J Respir Crit Care Med 194:719-28. | LEAK | F N | Permeabilized tissue | Mouse | Heart |
| Duteil 2016 Cell Rep | 2016 | Duteil D, Tosic M, Lausecker F, Nenseth HZ, Müller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Brüning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T, Schüle R (2016) Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue. Cell Rep 17:1008-21. | ET | F N S NS | Permeabilized tissue | Mouse | Fat |
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| McCurdy 2016 JCI Insight | 2016 | McCurdy CE, Schenk S, Hetrick B, Houck J, Drew BG, Kaye S, Lashbrook M, Bergman BC, Takahashi DL, Dean TA, Nemkov T, Gertsman I, Hansen KC, Philp A, Hevener AL, Chicco AJ, Aagaard KM, Grove KL, Friedman JE (2016) Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques. JCI Insight 1:e86612. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Other mammals | Skeletal muscle |
| Pravenec 2016 Physiol Genomics | 2016 | Pravenec M, Mlejnek P, Zídek V, Landa V, Šimáková M, Šilhavý J, Strnad H, Eigner S, Eigner Henke K, Škop V, Malínská H, Trnovská J, Kazdová L, Drahota Z, Mráček T, Houštěk J (2016) Autocrine effects of transgenic resistin reduce palmitate and glucose oxidation in brown adipose tissue. Physiol Genomics 48:420-7. | ET | F N | Isolated mitochondria | Rat | Fat |
| Holzem 2016 FASEB J | 2016 | Holzem KM, Vinnakota KC, Ravikumar VK, Madden EJ, Ewald GA, Dikranian K, Beard DA, Efimov IR (2016) Mitochondrial structure and function are not different between nonfailing donor and end-stage failing human hearts. FASEB J 30:2698-707. | OXPHOS LEAK | F N | Permeabilized tissue Isolated mitochondria | Human | Heart |
| Hamilton 2016 Physiol Rep | 2016 | Hamilton DJ, Minze LJ, Kumar T, Cao TN, Lyon CJ, Geiger PC, Hsueh WA, Gupte AA (2016) Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high-fat-fed ovariectomized mice. Physiol Rep 4. pii: e12913. | LEAK OXPHOS | F N NS | Isolated mitochondria | Mouse | Heart |
| Heim 2016 Thesis | 2016 | Heim A (2016) Tissue-specific seasonal changes in mitochondrial respiratory function and membrane composition in the golden-matled ground squirrel. Master's Thesis p77. | LEAK OXPHOS | F N NS Other combinations | Isolated mitochondria | Other mammals | Heart Skeletal muscle Liver Fat |
| Smith 2016 Diabetes | 2016 | Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR (2016) Salsalate (Salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK β1. Diabetes 65:3352-61. | LEAK OXPHOS ET | F N NS Other combinations ROX | Permeabilized cells Isolated mitochondria Permeabilized tissue | Mouse | Skeletal muscle Liver Fat |
| McFarlane 2016 Thesis | 2016 | McFarlane SV (2016) Temperature-dependent alterations of brown adipose tissue metabolism during hibernation in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus. Dissertation p74. | LEAK ROUTINE OXPHOS ET | F N | Isolated mitochondria Intact cells | Other mammals | Fat |
| Porter 2016 Cell Metab | 2016 | Porter C, Herndon DN, Chondronikola M, Chao T, Annamalai P, Bhattarai N, Saraf MK, Capek KD, Reidy PT, Daquinag AC, Kolonin MG, Rasmussen BB, Borsheim E, Toliver-Kinsky T, Sidossis LS (2016) Human and mouse brown adipose tissue mitochondria have comparable UCP1 function. Cell Metab 24:246-55. | LEAK OXPHOS ET | F N NS Other combinations | Permeabilized tissue | Human Mouse | Skeletal muscle Fat |
| Speijer 2016 Biochem J | 2016 | Speijer D (2016) Being right on Q: shaping eukaryotic evolution. Biochem J 473:4103-27. | F N ROX | ||||
| Kacso 2016 Biochem J | 2016 | Kacso G, Ravasz D, Doczi J, Németh B, Madgar O, Saada A, Ilin P, Miller C, Ostergaard E, Iordanov I, Adams D, Vargedo Z, Araki M, Araki K, Nakahara M, Ito H, Gál A, Molnár MJ, Nagy Z, Patocs A, Adam-Vizi V, Chinopoulos C (2016) Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations. Biochem J 473:3463-85. | LEAK OXPHOS | F N Other combinations | Isolated mitochondria | Mouse | Heart Nervous system Liver |
| Williams 2015 J Biol Chem | 2015 | Williams AS, Kang L, Zheng J, Grueter CA, Bracy DP, James FD, Pozzi A, Wasserman DH (2015) Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance. J Biol Chem 290:6546-57. | LEAK OXPHOS | F N | Permeabilized tissue | Mouse | Liver Other cell lines |
| Schoettl 2015 Mol Metab | 2015 | Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42. | LEAK ROUTINE OXPHOS ET | F N S ROX | Isolated mitochondria Intact cells | Mouse | Fat Other cell lines |
| Hanssen 2015 Nat Med | 2015 | Hanssen MJ, Hoeks J, Brans B, van der Lans AA, Schaart G, van den Driessche JJ, Jörgensen JA, Boekschoten MV, Hesselink MK, Havekes B, Kersten S, Mottaghy FM, van Marken Lichtenbelt WD, Schrauwen P (2015) Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus. Nat Med 21:863-5. | LEAK OXPHOS ET | F N NS Other combinations | Permeabilized tissue | Human | Skeletal muscle |
| Dueregger 2015 PLoS One | 2015 | Dueregger A, Schöpf B, Eder T, Höfer J, Gnaiger E, Aufinger A, Kenner L, Perktold B, Ramoner R, Klocker H, Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704. | LEAK ROUTINE OXPHOS ET | F N NS ROX | Permeabilized cells Permeabilized tissue | Human | Genital Other cell lines |
| Larsen 2015 Physiol Rep | 2015 | Larsen S, Scheede-Bergdahl C, Whitesell T, Boushel R, Bergdahl A (2015) Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia. Physiol Rep 3 pii:e12467. | LEAK OXPHOS | F N CIV NS Other combinations ROX | Permeabilized tissue | Rat | Skeletal muscle |
| Sidossis 2015 Cell Metab | 2015 | Sidossis LS, Porter C, Saraf MK, Børsheim E, Radhakrishnan RS, Chao T, Ali A, Chondronikola M, Mlcak R, Finnerty CC, Hawkins HK, Toliver-Kinsky T, Herndon DN (2015) Browning of subcutaneous white adipose tissue in humans after severe adrenergic stress. Cell Metab 22:219-27. | LEAK | F N NS Other combinations | Permeabilized cells | Human Mouse | Fat |
| Cappel 2015 PLoS One | 2015 | Cappel DA, Lantier L, Palmisano BT, Wasserman DH, Stafford JM (2015) CETP expression protects female mice from obesity-induced decline in exercise capacity. PLoS One 10:e0136915. | OXPHOS | F N | Permeabilized tissue | Mouse | Skeletal muscle |
| De Andrade 2015 Exp Cell Res | 2015 | de Andrade DC, de Carvalho SN, Pinheiro D, Thole AA, Moura AS, de Carvalho L, Cortez EA (2015) Bone marrow mononuclear cell transplantation improves mitochondrial bioenergetics in the liver of cholestatic rats. Exp Cell Res 336:15-22. | LEAK OXPHOS | F NS | Permeabilized tissue | Rat | Liver |
| Wessels 2015 Am J Physiol | 2015 | Wessels B, van den Broek NM, Ciapaite J, Houten SM, Wanders RJA, Nicolay K, Prompers JJ (2015) Carnitine supplementation in high-fat diet-fed rats does not ameliorate lipid-induced skeletal muscle mitochondrial dysfunction in vivo. Am J Physiol 309(7):E670-8. | LEAK OXPHOS ET | F N | Isolated mitochondria | Rat | Skeletal muscle |
| Hansen 2015 Obesity (Silver Spring) | 2015 | Hansen M, Lund MT, Gregers E, Kraunsøe R, Van Hall G, Helge JW, Dela F (2015) Adipose tissue mitochondrial respiration and lipolysis before and after a weight loss by diet and RYGB. Obesity (Silver Spring) 23:2022-9. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Fat |
| Assmann 2014 PhD Thesis | 2015 | Assmann N (2015) Impact of Fanconi-associated protein on the mitochonrial proteome. PhD Thesis 1-111. | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Intact cells | Pig | Kidney Other cell lines |
| Ofer 2015 Mol Endocrinol | 2015 | Ofer P, Heidegger I, Eder IE, Schöpf B, Neuwirt H, Geley S, Klocker H, Massoner P (2015) Both IGF1R and INSR knockdown exert anti-tumorigenic effects in prostate cancer in vitro and in vivo. Mol Endocrinol 29:1694-707. | ROUTINE OXPHOS ET | F N NS | Permeabilized cells Intact cells | Human | Genital Other cell lines |
| Siewiera 2015 Platelets | 2015 | Siewiera K, Kassassir H, Talar M, Wieteska L, Watala C (2015) Long-term untreated streptozotocin-diabetes leads to increased expression and elevated activity of prostaglandin H2 synthase in blood platelets. Platelets 27:203-11. | F ROX | Rat | Blood cells Platelet | ||
| Grevengoed 2015 J Lipid Res | 2015 | Grevengoed TJ, Martin SA, Katunga L, Cooper DE, Anderson EJ, Murphy RC, Coleman RA (2015) Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res 56:1572-82. | LEAK OXPHOS | F N NS ROX | Permeabilized tissue | Mouse | Heart Other cell lines HEK |
| Aroor 2015 Diabetes | 2015 | Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001. | LEAK ROUTINE OXPHOS ET | F N S NS | Isolated mitochondria | Mouse | Liver |
| Christiansen 2015 J Vet Med Sci | 2015 | Christiansen LB, Dela F, Koch J, Yokota T (2015) Tissue-specific and substrate-specific mitochondrial bioenergetics in feline cardiac and skeletal muscles. J Vet Med Sci 77:669-75. | LEAK OXPHOS ET | F N S CIV NS Other combinations ROX | Permeabilized tissue | Cat | Heart Skeletal muscle |
| Johnson 2015 Aging Cell | 2015 | Johnson ML, Lalia AZ, Dasari S, Pallauf M, Fitch M, Hellerstein MK, Lanza IR (2015) Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice. Aging Cell 14:734-43. | LEAK OXPHOS | F N S NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
| Van de Weijer 2015 Diabetes | 2015 | van de Weijer T, Phielix E, Bilet L, Williams EG, Ropelle ER, Bierwagen A, Livingstone R, Nowotny P, Sparks LM, Paglialunga S, Szendroedi J, Havekes B, Moullan N, Pirinen E, Hwang JH, Schrauwen-Hinderling VB, Hesselink MK, Auwerx J, Roden M, Schrauwen P (2015) Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans. Diabetes 64:1193-201. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Lantier 2015 Diabetes | 2015 | Lantier L, Williams AS, Williams IM, Yang KK, Bracy DP, Goelzer M, James FD, Gius D, Wasserman DH (2015) SIRT3 is crucial for maintaining skeletal muscle insulin action and protects against severe insulin resistance in high fat fed mice. Diabetes 64:3081-92. | LEAK OXPHOS | F N | Permeabilized tissue | Mouse | Skeletal muscle |
| Katunga 2015 Mol Metab | 2015 | Katunga LA, Gudimella P, Efird JT, Abernathy S, Mattox TA, Beatty C, Darden TM, Thayne KA, Alwair H, Kypson AP, Virag JA, Anderson EJ (2015) Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy. Mol Metab 4:493-506. | LEAK OXPHOS | F | Permeabilized tissue | Mouse | Heart |
| Ramos-Filho 2015 PLoS One | 2015 | Ramos-Filho D, Chicaybam G, de-Souza-Ferreira E, Guerra Martinez C, Kurtenbach E, Casimiro-Lopes G, Galina A (2015) High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles. PLoS One 10:e0131766. | LEAK OXPHOS ET | F N S Gp NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
| Porter 2015 Shock | 2015 | Porter C, Herndon DN, Bhattarai N, Ogunbileje JO, Szczesny B, Szabo C, Toliver-Kinsky T, Sidossis LS (2015) Severe burn injury induces thermogenically functional mitochondria in murine white adipose tissue. Shock 44:258-64. | LEAK | F N S NS Other combinations | Permeabilized tissue | Mouse | Fat |
| Koliaki 2015 Cell Metab | 2015 | Koliaki C, Szendroedi J, Kaul K, Jelenik T, Nowotny P, Jankowiak F, Herder C, Carstensen M, Krausch M, Knoefel WT, Schlensak M, Roden M (2015) Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. Cell Metab 21:739-46. | LEAK OXPHOS ET | F N NS Other combinations ROX | Homogenate Isolated mitochondria | Human | Liver |
| Conner 2015 FASEB J | 2015 | Conner B, Hetrik B, Chicco A, McCurdy C (2015) Maternal obesity alters offspring muscle mitochondrial function in nonhuman primates. FASEB J 29:1036.7. | LEAK OXPHOS | F | Permeabilized tissue | Other mammals | Skeletal muscle |
| Ludzki 2015 Diabetes | 2015 | Ludzki A, Paglialunga S, Smith BK, Herbst EA, Allison MK, Heigenhauser GJ, Neufer PD, Holloway GP (2015) Rapid repression of ADP transport by palmitoyl-CoA is attenuated by exercise training in humans; a potential mechanism to decrease oxidative stress and improve skeletal muscle insulin signaling. Diabetes 64:2769-79. | LEAK OXPHOS | F N NS | Permeabilized tissue | Human Mouse | Skeletal muscle |
| Hagve 2015 Am J Physiol Endocrinol Metab | 2015 | Hagve M, Gjessing PF, Fuskevåg OM, Larsen TS, Irtun Ø (2015) Skeletal muscle mitochondria exhibit decreased pyruvate oxidation capacity and increased ROS emission during surgery-induced acute insulin resistance. Am J Physiol Endocrinol Metab 308:E613-20. | LEAK OXPHOS | F N | Isolated mitochondria | Pig | Skeletal muscle Liver |
| Beauchamp 2015 Biosci Rep | 2015 | Beauchamp B, Thrush AB, Quizi J, Antoun G, McIntosh N, Al-Dirbashi OY, Patti ME, Harper ME (2015) Undernutrition during pregnancy in mice leads to dysfunctional cardiac muscle respiration in adult offspring. Biosci Rep 35. pii:e00200. | LEAK OXPHOS | F NS Other combinations ROX | Homogenate | Mouse | Heart Liver |
| Hanssen 2015 Diabetologia | 2015 | Hanssen MJ, Wierts R, Hoeks J, Gemmink A, Brans B, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2015) Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance. Diabetologia 58:586-95. | LEAK ET | F | Isolated mitochondria | Human | Skeletal muscle |
| Paglialunga 2015 Diabetologia | 2015 | Paglialunga S, Ludzki A, Root-McCaig J, Holloway GP (2015) In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice. Diabetologia 58:1071-80. | LEAK OXPHOS | F N | Permeabilized tissue | Mouse | Fat |
| Joergensen 2015 J Cereb Blood Flow Metab | 2015 | Jørgensen T, Grunnet N, Quistorff B (2015) One-year high fat diet affects muscle-but not brain mitochondria. J Cereb Blood Flow Metab 35:943-50. | LEAK OXPHOS | F N S Other combinations | Isolated mitochondria | Rat | Skeletal muscle Nervous system |
| Den Besten 2015 Diabetes | 2015 | den Besten G, Bleeker A, Gerding A, van Eunen K, Havinga R, van Dijk TH, Oosterveer MH, Jonker JW, Groen AK, Reijngoud DJ, Bakker BM (2015) Short-chain fatty acids protect against high-fat diet-induced obesity via a PPARγ-dependent switch from lipogenesis to fat oxidation. Diabetes 64:2398-408. | LEAK OXPHOS | F | Isolated mitochondria | Mouse | Liver |
| Wessels 2015 Diabetes Obes Metab | 2015 | Wessels B, Ciapaite J, van den Broek NM, Houten SM, Nicolay K, Prompers JJ (2015) Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes. Diabetes Obes Metab 17:52-60. | LEAK OXPHOS ET | F N S | Isolated mitochondria | Rat | Skeletal muscle |
| Desprat 2015 Thesis | 2015 | Desprat JL, Teulier L, Puijalon S, Romestaing C, Dumet A, Lengagne T, Mondy N (2015) Caloric restriction and testosterone affect mitochondrial functioning and contractile properties of calling muscles in Hyla arborea.. Doctoral Thesis p153. | LEAK OXPHOS | F NS | Permeabilized tissue | Amphibians | Skeletal muscle |
| Christiansen 2015 Am J Physiol Heart Circ Physiol | 2015 | Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue Isolated mitochondria | Cat | Heart Skeletal muscle |
| Guadalupe-Grau 2015 J Sports Sci | 2015 | Guadalupe-Grau A, Plenge U, Helbo S, Kristensen M, Andersen PR, Fago A, Belhage B, Dela F, Helge JW (2015) Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males. J Sports Sci 33:570-8. | LEAK OXPHOS | F N NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
| Schrauwen-Hinderling 2015 Antioxid Redox Signal | 2015 | Schrauwen-Hinderling VB, Kooi ME, Schrauwen P (2015) Mitochondrial function and diabetes; consequences for skeletal and cardiac muscle metabolism. Antioxid Redox Signal 24:39-51. | LEAK OXPHOS | F N S CIV | Permeabilized tissue Isolated mitochondria | Human | Heart Skeletal muscle |
| Saraf 2015 J Burn Care Res | 2015 | Saraf MK, Herndon DN, Porter C, Toliver-Kinsky T, Radhakrishnan R, Chao T, Chondronikola M, Sidossis LS (2015) Morphological changes in subcutaneous white adipose tissue after severe burn injury. J Burn Care Res 37:e96-e103. | LEAK OXPHOS | F N Other combinations | Permeabilized tissue | Human | Fat |
| Hanssen 2015 Diabetes | 2015 | Hanssen MJ, van der Lans AA, Brans B, Hoeks J, Jardon KM, Schaart G, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2015) Short-term cold acclimation recruits brown adipose tissue in obese humans. Diabetes 65:1179-89. | LEAK OXPHOS ET | F N NS Other combinations | Permeabilized tissue | Human | Skeletal muscle |
| Janssens 2015 Nutr Metab (Lond) | 2015 | Janssens S, Heemskerk MM, van den Berg SA, van Riel NA, Nicolay K, Willems van Dijk K, Prompers JJ (2015) Effects of low-stearate palm oil and high-stearate lard high-fat diets on rat liver lipid metabolism and glucose tolerance. Nutr Metab (Lond) 12:57. | LEAK OXPHOS | F N | Isolated mitochondria | Rat | Liver |
| Patil 2015 J Nutr Biochem | 2015 | Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47. | LEAK OXPHOS ET | F N S Gp ROX | Isolated mitochondria | Mouse | Skeletal muscle Liver Fat |
| Porter 2015 Am J Physiol Endocrinol Metab | 2015 | Porter C, Hurren NM, Cotter MV, Bhattarai N, Reidy PT, Dillon EL, Durham WJ, Tuvdendorj D, Sheffield-Moore M, Volpi E, Sidossis LS, Rasmussen BB, Børsheim E (2015) Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle. Am J Physiol Endocrinol Metab 309:E224-32. | LEAK OXPHOS ET | F N NS Other combinations | Permeabilized tissue | Human | Skeletal muscle |
| Seillier 2015 EMBO Mol Med | 2015 | Seillier M, Pouyet L, N'Guessan P, Nollet M, Capo F, Guillaumond F, Peyta L, Dumas JF, Varrault A, Bertrand G, Bonnafous S, Tran A, Meur G, Marchetti P, Ravier MA, Dalle S, Gual P, Muller D, Rutter GA, Servais S, Iovanna JL, Carrier A (2015) Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 7:802-18. | LEAK ROUTINE OXPHOS ET | F CIV NS ROX | Permeabilized cells Intact cells | Human Mouse | Fibroblast |
| Grabez 2015 J Anim Sci | 2015 | Grabež V, Kathri M, Phung V, Moe KM, Slinde E, Skaugen M, Saarem K, Egelandsdal B (2015) Protein expression and oxygen consumption rate of early postmortem mitochondria relate to meat tenderness. J Anim Sci 93:1967-79. | LEAK OXPHOS ET | F N S NS Other combinations ROX | Permeabilized tissue | Bovines | Skeletal muscle |
| Rodrigues 2016 Biochem J | 2015 | Rodrigues MF, Obre E, Melo FH, Santos-Jr GC, Galina A, Jasiulionis MG, Rossignol R, Rumjanek FD, Amoedo ND (2016) Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells. https://doi.org/10.1042/BJ20150645 | LEAK ROUTINE OXPHOS ET | F N S ROX | Permeabilized cells Intact cells | Mouse | Endothelial;epithelial;mesothelial cell Other cell lines |
| Van Ewijk 2015 Obesity (Silver Spring) | 2015 | van Ewijk PA, Paglialunga S, Kooi ME, Nunes PM, Gemmink A, Slenter J, Kornips E, Jörgensen JA, Hoeks J, Wildberger JE, Hesselink MK, Glatz JF, Heerschap A, Kersten S, Schrauwen P, Schrauwen-Hinderling VB (2015) Effects of high-fat feeding on ectopic fat storage and postprandial lipid metabolism in mouse offspring. Obesity (Silver Spring) 23:2242-50. | LEAK OXPHOS | F N | Isolated mitochondria | Mouse | Heart Liver |
| Coen 2015 Diabetes | 2015 | Coen PM, Menshikova EV, Distefano G, Zheng D, Tanner CJ, Standley RA, Helbling NL, Dubis GS, Ritov VB, Xie H, Desimone ME, Smith SR, Stefanovic-Racic M, Toledo FG, Houmard JA, Goodpaster BH (2015) Exercise and weight loss improve muscle mitochondrial respiration, lipid partitioning, and insulin sensitivity after gastric bypass surgery. Diabetes 64:3737-50. | LEAK OXPHOS ET | F N NS Other combinations | Permeabilized tissue | Human | Skeletal muscle |
| ... further results | |||||||
- »Abstracts: FAO, F-pathway control state
Sort in ascending/descending order by a click on one of the small symbols in squares below.
| Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
|---|---|---|---|---|---|---|---|
| Komlodi 2023 EUROMIT2023 Bologna | 2023 | Komlódi T, Silva FSG, Duarte AI, Mena D, Garcia-Souza LF, Makrecka-Kuka M, Bento G, Grilo LF, Oliveira PJ, Gnaiger E (2023) Off-target effects of etomoxir: inhibition of mitochondrial Complex I and fatty acid oxidation. EUROMIT2023 International Conference on Mitochondrial Pathology. | F N S CIV | Permeabilized cells Isolated mitochondria Intact cells | Human Mouse | Nervous system Liver | |
| Timon-Gomez 2023 EUROMIT2023 Bologna | 2023 |  | OXPHOS ET | F N S Gp | Homogenate Isolated mitochondria Intact cells | Human Mouse | Heart Nervous system HEK |
| Cecatto 2023 BPS2023 San Diego | 2023 |  | OXPHOS | F N Gp NS | Permeabilized tissue Homogenate | Mouse | Heart Nervous system Kidney |
| Cardoso 2022a EBEC | 2022 |  | LEAK OXPHOS ET | F N S NS | Permeabilized cells | Human | HEK |
| Molina 2022 Abstract Bioblast | 2022 | 3.2. «10+5»  »Bioenergetics Communications«  | OXPHOS ET | F N S Gp ROX | Permeabilized cells | Human | Blood cells |
| Isola 2022 Abstract Bioblast | 2022 | P12.  | OXPHOS ET | F N S DQ CIV | Isolated mitochondria | Rat | Heart Nervous system |
| Santos 2019 MiPschool Coimbra | 2019 |  | OXPHOS | F N | Human | Heart Fat | |
| Kandel 2019 Biophys J | 2019 | Kandel SM, Tomar N, Zheleznova N, Audi SH, Cowley Jr AW, Dash RK (2019) Calcium stimulation of mitochondrial respiration is substrate dependent and tissue specific. Biophys J. | LEAK OXPHOS | F N S | Isolated mitochondria | Rat | Heart Kidney |
| Silva 2019 ESCI2019 | 2019 | Silva FSG, Komlodi T, Garcia-Souza LF, Bento G, Doerrier C, Oliveira PJ, Gnaiger E (2019) Can fatty acid oxidation be specifically blocked by the CPT1 inhibitor etomoxir? | OXPHOS ET | F N S | Permeabilized cells Isolated mitochondria | Human Mouse | Liver |
| Minuzzi 2019 MiPschool Coimbra | 2019 | | LEAK OXPHOS ET | F N S | Permeabilized tissue | Mouse | Endothelial;epithelial;mesothelial cell |
| Silva 2019 MiPschool Coimbra | 2019 |  | OXPHOS ET | F N Other combinations | Permeabilized cells Isolated mitochondria | Human Mouse | Liver |
| Axelrod 2019 Abstract IOC141 | 2019 | Axelrod CL, Davuluri G, Zunica ERM, Noland RC, Hoppel CL, Kirwan JP (2019) Administration of BAM15 to obese C57BL/6J mice increases skeletal muscle fatty acid oxidation independent of OXPHOS or ETC capacity. Mitochondr Physiol Network 24.02. | OXPHOS ET | F | Mouse | Skeletal muscle | |
| Sumbalova 2019b MiP2019 | 2019 |  | LEAK OXPHOS | F N S Gp CIV NS ROX | Intact cells | Human | Platelet |
| Sumbalova 2019a MiP2019 | 2019 | | LEAK OXPHOS | F N S Gp CIV NS ROX | Intact cells | Human | Platelet |
| Keller 2018 MiP2018 | 2018 |  | F N | Intact cells | Mouse | Heart Nervous system | |
| Chang 2018 Life Sciences Meeting 2018 Innsbruck AT | 2018 | pH dependence of mitochondrial respiration and H2O2 production in oral cancer cells – a pilot study. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells | Human | HEK Kidney |
| Schoepf 2018 33rd Annual EAU Congress Copenhagen | 2018 | Shift of mitochondrial oxidative phosphorylation is associated with mtDNA mutational load in primary prostate cancer tissue. | LEAK OXPHOS ET | F N NS Other combinations ROX | Permeabilized cells Permeabilized tissue | Human | Genital |
| Doerrier 2018 ESCI2018 | 2018 |  | LEAK ROUTINE OXPHOS ET | F N S Gp ROX CIV | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria | Human Mouse | Heart Skeletal muscle Nervous system Blood cells HEK |
| Doerrier 2018 EBEC2018 | 2018 | | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Heart Nervous system Blood cells HEK Platelet |
| Stankova 2018 MiP2018 | 2018 |  | OXPHOS ET | S F N | Homogenate | Mouse | Liver |
| Pereira da Silva Grilo da Silva 2018 MiP2018 | 2018 | | OXPHOS ET | F N S NS Other combinations | Permeabilized cells Isolated mitochondria | Human Mouse | Nervous system Liver Other cell lines |
| Nemec 2018 MiP2018 | 2018 |  | LEAK | F N NS Other combinations | Permeabilized tissue | Human | Skeletal muscle |
| Chicco 2018 MiP2018b | 2018 |  | OXPHOS | F N NS | Permeabilized tissue | Mouse | Heart |
| McCurdy 2018 Endocrine Reviews | 2018 | McCurdy CE, True C, Takahashi D, Hetrick B, Varlamov O, Roberts CT (2018) Chronic hyperandrogenemia impairs oxidative metabolism in skeletal muscle from adolescent female rhesus macaques. Endocrine Reviews. | ET | F | Permeabilized tissue | Other mammals | Skeletal muscle |
| Makrecka-Kuka 2018 MiP2018 | 2018 |  | OXPHOS | F | Homogenate | Mouse Rat | Nervous system |
| Gnaiger 2018 MiP2018 | 2018 |  | OXPHOS | N F S Gp DQ CIV NS Other combinations | |||
| Doerrier 2018 MiP2018b | 2018 | | OXPHOS | F N | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Heart Nervous system Blood cells HEK Platelet |
| Gnaiger 2018 MiPschool Tromso A1 | 2018 |  | LEAK ET OXPHOS | F N S Gp DQ CIV NS Other combinations | |||
| Konopka 2018 FASEB J | 2018 | Konopka AR, Castor WM, Reid J, Schoenberg H, Laurin J, Wolff C, Hamilton K, Miller B (2018) Metformin blunts exercise-induced improvements in skeletal muscle mitochondrial respiration independent of changes in mitochondrial biogenesis. FASEB J. | OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
| Votion 2018 MiP2018 | 2018 |  | OXPHOS | F N S NS | Intact cells | Horse | Skeletal muscle |
| Dubouchaud 2017 Abstract MITOEAGLE Barcelona | 2017 |  | OXPHOS | F N | Permeabilized tissue Isolated mitochondria | Rat | Skeletal muscle Liver |
| Holzknecht 2017 MiPschool Obergurgl | 2017 | | F N | Mouse | Heart | ||
| Waldauf 2017 MITOEAGLE Obergurgl | 2017 | | LEAK OXPHOS ET | F N S CIV NS | Homogenate | Human | Skeletal muscle |
| Isola 2017 MiPschool Obergurgl | 2017 | | OXPHOS | F N | Isolated mitochondria | Rat | |
| O'Brien 2017 Abstract IOC122 | 2017 | PPARα independent effects of nitrate supplementation on skeletal muscle mitochondrial function in hypoxia. | LEAK OXPHOS | F | Mouse | Skeletal muscle | |
| Distefano 2017 MiPschool Obergurgl | 2017 |  | LEAK OXPHOS ET | F NS | Permeabilized tissue | Human | Skeletal muscle |
| Collins 2017 MiPschool Obergurgl | 2017 | | OXPHOS | F N S Gp CIV NS ROX | Intact cells | ||
| Amick 2017 MiPschool Obergurgl | 2017 |  | LEAK OXPHOS | F N | Isolated mitochondria | Other mammals | Nervous system |
| Doerrier 2017 Abstract MitoEAGLE Barcelona | 2017 | | LEAK ROUTINE OXPHOS ET | F N S Gp CIV | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Heart Nervous system HEK |
| Nemec 2017 Abstract MITOEAGLE Barcelona | 2017 | | OXPHOS ET | F | Permeabilized tissue | Human | Skeletal muscle |
| Sobotka 2017 Abstract MITOEAGLE Barcelona | 2017 | | OXPHOS ET | F N S Gp ROX | Isolated mitochondria | Rat | Liver |
| Doerrier 2017 MiPschool C2 | 2017 | | LEAK ROUTINE OXPHOS ET | F N S Gp CIV | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Heart Nervous system HEK |
| Gnaiger 2017 MiPschool A4 | 2017 | | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Permeabilized tissue Isolated mitochondria | |||
| Ukropec 2017 MITOEAGLE Obergurgl | 2017 | | LEAK OXPHOS ET | F N S Gp NS | Permeabilized cells | Skeletal muscle | |
| Wu 2017 FASEB J | 2017 | Effects of eccentric and concentric cycling exercise regimens on hypoxia-mediated mitochondrial bioenergetics of platelets in sedentary males. | F N S Gp | Human | Blood cells Platelet | ||
| Hoppel 2017 MiP2017 | 2017 |  | OXPHOS | F N S | Rat | Liver | |
| Doerrier 2017 MiP2017 C1 | 2017 | | LEAK ET | F N S CIV NS | Isolated mitochondria | Mouse | Heart |
| Urban 2017 MiP2017 | 2017 | | F N NS | Homogenate | Human | Skeletal muscle | |
| Lemieux 2017 MiP2017 | 2017 |  | OXPHOS | F CIV | Permeabilized tissue | Rat | Heart |
| Brazdova 2017 MiP2017 | 2017 |  | F N NS | Isolated mitochondria | Fat | ||
| Nakajima 2017 Europ Heart J | 2017 | Mitochondrial dysfunction in epicardial adipose tissue; possible role in progression of coronary artery disease. | OXPHOS | F N NS | Permeabilized tissue | Human | Fat |
| Scheiber 2017 Europ Heart J | 2017 | High-resolution respirometry in human endomyocardial biopsies to assess myocardial mitochondrial function. | OXPHOS | F N NS | Permeabilized tissue | Human | Heart |
| Gnaiger 2016 Abstract UMDF2016 | 2016 | Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells. | LEAK OXPHOS ET | F N NS | Permeabilized cells Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell Genital Other cell lines Fibroblast |
| Pileggi 2016 Abstract MitoFit Science Camp 2016 | 2016 | Voluntary exercise prevents high fat diet-induced cardiac mitochondrial dysfunction in male rats. | F N NS | Permeabilized tissue | Rat | Heart | |
| Chicco 2016b Abstract MitoFit Science Camp 2016 | 2016 | OXPHOS coupling efficiency of permeabilized muscle fibers predicts metabolic efficiency of subjects exercising at 5260 m. | LEAK OXPHOS ET | F N | Permeabilized tissue | Human | Skeletal muscle |
| Osiki 2016 Abstract MitoFit Science Camp 2016 | 2016 | Suitability of octanoylcarnitine & malate for assessment of beta oxidation capacity by respirometry in aconitase-inhibited samples. | OXPHOS ET | F N Other combinations | Rat | Skeletal muscle | |
| Krajcova 2016 Abstract MitoFit Science Camp 2016 | 2016 | Mitochondrial pathogenesis of propofol infusion syndrome in an in vitro model of human skeletal muscle. | LEAK ET | F | Homogenate | Human | Skeletal muscle |
| Chicco 2016c Abstract MitoFit Science Camp 2016 | 2016 | Investigating the mechanism of cardiac mitochondrial respiratory impairment in Barth Syndrome. | OXPHOS | F N S CIV Other combinations | Mouse | Heart | |
| Hoppel 2016a Abstract MitoFit Science Camp 2016 | 2016 | Skeletal muscle mitochondria in diagnostic studies. | F N Other combinations | Isolated mitochondria | Human | Skeletal muscle Liver | |
| Makrecka-Kuka 2016 Abstract MitoFit Science Camp 2016 | 2016 | Long-chain acylCoAs vs acylcarnitines in mitochondrial bioenergetics: from in vitro to in vivo. | OXPHOS | F | Isolated mitochondria | Rat | Heart |
| Sumbalova 2016b Abstract MitoFit Science Camp 2016 | 2016 | Human blood cells: isolation and HRR. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Intact cells | Human | Blood cells Lymphocyte Platelet |
| Lamberti 2016 Abstract MitoFit Science Camp 2016 | 2016 | Development of a reference sample for HRR. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Human | Kidney HEK | |
| Doerrier 2016 Abstract MitoFit Science Camp 2016 | 2016 | Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria | Human Mouse | Heart Blood cells HEK Platelet |
| Kane 2016 Abstract MitoFit Science Camp 2016 | 2016 | Effects of inhibiting myosin-ATPase on mitochondrial respiratory capacity in permeabilized skeletal muscle. | OXPHOS | F N | Permeabilized tissue | Rat | Skeletal muscle |
| Laner 2016 Abstract MitoFit Science Camp 2016 | 2016 | OXPHOS and ET-capacity in permeabilized fibers of canine superathletes. Analysis of HRR data presenting unexpected challenges. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Dog | Skeletal muscle |
| Sobotka 2016 Abstract IOC116 | 2016 | Sobotka O, Kucera Otto, Stankova P, Endlicher R, Nozickova K, Banni A, Cervinkova Z (2016) Mitochondrial respiration in fatty liver. Mitochondr Physiol Network 21.11 | LEAK OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Isolated mitochondria | Rat | Liver |
| Cecatto 2016 Abstract IOC116 | 2016 | Cecatto C, Silva JC, Wajner A, Godoy KS, Ribeiro, RT, Amaral AU, Wajner M (2016) cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca2+ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver. Mitochondr Physiol Network 21.11 | LEAK OXPHOS ET | F N CIV Other combinations | Permeabilized tissue Isolated mitochondria | Rat | Nervous system Liver |
| Sumbalova 2016 Abstract Mito Xmas Meeting Innsbruck | 2016 | Methods for evaluation of mitochondrial membrane potential with multi-sensor high-resolution respirometry: potentiometry vs fluorometry. | LEAK OXPHOS ET | F N S NS ROX | Mouse | Nervous system | |
| Laner 2016 Abstract Mito Xmas Meeting Innsbruck | 2016 | OXPHOS and ET capacity in permeabilized fibers of canine superathletes. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Dog | Skeletal muscle |
| Garcia-Souza 2016 Abstract Mito Xmas Meeting Innsbruck | 2016 | Assessment of fatty acid oxidation in mouse brain and liver mitochondria. | OXPHOS | F N | Homogenate Isolated mitochondria | Nervous system Liver | |
| Doerrier 2016b Abstract Mito Xmas Meeting Innsbruck | 2016 | Searching for specific targets of ischemic damage of cardiac mitochondria using O2k-Fluorometry. | LEAK OXPHOS ET | F N S Gp CIV ROX | Isolated mitochondria | Mouse | Heart |
| Chang 2015 Abstract EB2015 | 2015 | Different effects of interval and continuous exercise regimens on capacity of mitochondria oxidative phosphorylation in lymphocyte. | F N NS | Permeabilized cells Intact cells | Human | Macrophage-derived | |
| Schoettl 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Schoettl 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Isolated mitochondria | Nervous system Liver Fat HEK | ||
| Hansson Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Hansson 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Heart | ||
| Lund 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Lund 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Homogenate Isolated mitochondria | |||
| Filippi 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Filippi 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Liver | |||
| Ali 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Ali 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Intact cells | |||
| Weber 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Weber 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Human Mouse | Genital | ||
| Cabrera-Fuentes 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Cabrera-Fuentes 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | ||||
| Wuest 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Wuest 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | OXPHOS ET | F N S NS ROX | Permeabilized tissue | Rat | Heart |
| Madlala 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Madlala 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | OXPHOS | F | Permeabilized tissue | Rat | Skeletal muscle |
| McCurdy 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Cannon 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | OXPHOS | F N | Permeabilized tissue | Other mammals | Skeletal muscle |
| Essop 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Essop 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Coen 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Coen 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | OXPHOS | F N NS | Permeabilized tissue | ||
| Miller 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Miller 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Chicco 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Chicco 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Gottschalk 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Gottschalk 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Moellering 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Moellering 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Skeletal muscle | ||
| Bouitbir 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Bouitbir 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Heart Skeletal muscle | ||
| Makrecka 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Makrecka 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue Isolated mitochondria | Mouse Rat | Heart Skeletal muscle | |
| Roden 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Roden 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Human Mouse | Skeletal muscle | |
| Baekkerud 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Baekkerud 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Mouse | ||
| Salin 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Salin 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue Homogenate | Fishes | Skeletal muscle | |
| Ramsay 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Ramsay 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Chavanelle 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Chavanelle 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | LEAK OXPHOS | F N | Permeabilized tissue | Mouse | Skeletal muscle |
| Kollberg 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Kollberg 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Isolated mitochondria | |||
| Veksler 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Veksler 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Heart Skeletal muscle | ||
| Jelenik 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Jelenik 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Pasdois 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Cannon 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue Isolated mitochondria | |||
| Hickey 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Hickey 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue Isolated mitochondria | Rat Fishes | Heart | |
| Fontes-Oliveira 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Fontes-Oliveira 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue Intact cells | |||
| West 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | West 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Cannon 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Cannon 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human Mouse | Skeletal muscle |
| Ost 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Ost 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Mouse | Skeletal muscle | |
| Neviere 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Neviere 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Human Mouse | ||
| Gorr 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Gorr 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Wright 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Wright 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Laner 2015 Abstract MiP2015 | 2015 | Comparative mitochondrial physiology: OXPHOS and ET capacity in permeabilized fibers of canine superathletes. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Dog | Skeletal muscle |
| Amoedo 2015 Abstract MiP2015 | 2015 | The energy requirement of metastatic cells. | F S | Mouse Rat | Other cell lines | ||
| Laner 2015 Abstract MiPschool Greenville 2015 | 2015 | Comparative mitochondrial physiology: OXPHOS and ET capacity in permeabilized fibers of canine superathletes. | OXPHOS ET | F N S NS | Permeabilized tissue | Dog | Skeletal muscle |
| Lemieux 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Lemieux 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Heart Skeletal muscle | ||
| Villena 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Villena 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Intact cells | Fat | ||
| Trifunovic 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Trifunovic 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Isolated mitochondria | Heart | ||
| Mahdaviani 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Mahdaviani 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Isolated mitochondria | Fat | ||
| Hagland 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Hagland 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Isolated mitochondria Intact cells | |||
| Cortassa 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Cortassa 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Isolated mitochondria Intact cells | Skeletal muscle | ||
| Gottlieb 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Gottlieb 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Mouse | Skeletal muscle | ||
| Robidoux 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Robidoux 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Intact cells | Fat | ||
| Kaambre 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Cannon 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Human | Genital | ||
| Goetzman 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Goetzman 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Homogenate | Liver | ||
| Krishnan 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Krishnan 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Liver | |||
| Palm 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Palm 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | ||||
| Chou 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Chou 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | OXPHOS ET | F N S NS ROX | Permeabilized cells Permeabilized tissue | Blood cells Lymphocyte Platelet | |
| Ciapaite 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Ciapaite 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | LEAK OXPHOS ET | F | Permeabilized tissue | Human Rat | Skeletal muscle |
| Kane 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Kane 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Votion 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Votion 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Mouse | ||
| Goodpaster 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Goodpaster 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Lesnefsky 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Lesnefsky 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Van Schaardenburgh 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Van Schaardenburgh 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | |||
| Schauer 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Schauer 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | OXPHOS ET | F | Permeabilized tissue | ||
| Smith 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Smith 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | OXPHOS ET | F | Permeabilized tissue | ||
| Senyilmaz 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Senyilmaz 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Drosophila | Skeletal muscle | |
| Ojuka 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Ojuka 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | OXPHOS ET | F | Permeabilized tissue | ||
| Darveau 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Darveau 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Hexapods | Skeletal muscle | |
| Wohlwend 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Wohlwend 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Human Rat | Skeletal muscle | |
| Ljubkovic 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Ljubkovic 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | OXPHOS ET | F N NS | Permeabilized tissue | Human | Heart |
| Sparks 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Sparks 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Human Mouse | Skeletal muscle | |
| Egelandsdal 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | 2015 | Egelandsdal 2015 Fatty Acid Oxidation O2k-Network Discussion Forum | F | Permeabilized tissue | Bovines | Skeletal muscle | |
| Sumbalova 2014 Abstract MiP2014 | 2014 | Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain. | OXPHOS ET | F N S NS | Isolated mitochondria | Rat | Nervous system Liver |
| Amoedo 2014 Abstract MiP2014 | 2014 | The metabolic panorama during tumor progression towards malignancy. | OXPHOS | F S | Permeabilized cells | Other cell lines | |
| Bresciani Martins de Andrade 2014 Abstract MiP2014 | 2014 | Mitochondrial function in white adipose tissue: palmitoleic acid (C16:1n7) treatment enhances white adipocyte oxygen consumption. | F | Intact cells | Fat | ||
| Rodrigues 2014 Abstract MiP2014 | 2014 | Bioenergetics’ traits of tongue cancer metastatic cells. | F N S | Permeabilized cells | Mouse | Lymphocyte | |
| Larsen 2014 Abstract MiP2014 | 2014 | The effect of high intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue. | OXPHOS | F N S NS | Permeabilized tissue | Human | Skeletal muscle Fat |
| Horscroft 2014 Abstract MiP2014 | 2014 | Substrate utilisation in the hypoxic heart: a glycolysis/glucose oxidation mismatch? | OXPHOS | F N | Rat | Heart | |
| Gnaiger 2013 Abstract Mito2013 | 2013 | Gnaiger E, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet J, Christiansen M, Helge JW, Saltin B, Boushel R (2013) Conserved mitochondrial coupling efficiency and adaptive substrate control in Inuit and Caucasians: adaptation and acclimatization to the Arctic winter. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Human | Skeletal muscle |
| Chicco 2013 Abstract IOC79 | 2013 | Chicco AJ (2013) Substrate-specific impairment of oxidative phosphorylation in Tafazzin-deficient cardiac mitochondria: potential role of CoA deficiency. Mitochondr Physiol Network 18.07 | OXPHOS | F N S | Permeabilized cells Isolated mitochondria | Mouse | Heart |
| Cavalcanti de Albuquerque 2013 Abstract MiP2013 | 2013 | Cavalcanti de Albuquerque JP, Salvador IC, Martins EG, Jardim-Messeder D; Werneck de Castro JPS; Carvalho DP; Galina A (2013) Skeletal muscle mitochondrial function in ovariectomized rats: A time course study and the role of estrogen replacement. Mitochondr Physiol Network 18.08. | LEAK OXPHOS ET | F N S Gp NS ROX | Intact organism Permeabilized tissue | Rat | Skeletal muscle |
| Votion 2013 Abstract MiP2013 | 2013 | Votion DM, Mouithys-Mickalad A, Ceusters Justine D, Lemieux H, Tosi I, Franck T, Art T, Niesten A, Serteyn D (2013) The challenge of understanding myopathies in horses using permeabilized muscle cells. Mitochondr Physiol Network 18.08. | OXPHOS ET | F N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
| Quistorff 2013 Abstract MiP2013 | 2013 | Quistorff B (2013) With type 2 diabetes mitochondrial dysfunction develops earlier in liver than in skeletal muscle. Mitochondr Physiol Network 18.08. | LEAK OXPHOS | F S Other combinations | Rat | Skeletal muscle Liver | |
| Oliveira MF 2013 Abstract MiP2013 | 2013 | Oliveira MF (2013) Comparative mitochondrial physiology in blood feeding insect vectors and parasites. Mitochondr Physiol Network 18.08. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV ROX | Intact organism Intact organ Permeabilized cells Permeabilized tissue Homogenate Intact cells | Human Drosophila Hexapods Other invertebrates | Skeletal muscle Neuroblastoma |
| Lemieux 2013 Abstract MiP2013 | 2013 | Lemieux H, Warren BE, Lucchinetti E, Lou PH, Zhang L, Gandhi M, Clanachan AS, Zaugg M(2013) Early mitochondrial dysfunction associated with type 2 diabetes mellitus in the heart and skeletal muscle. Mitochondr Physiol Network 18.08. | OXPHOS | F N S CIV NS Other combinations | Permeabilized tissue | Rat | Heart Skeletal muscle |
| Kotwica 2013 Abstract MiP2013 | 2013 | Kotwica AO, Horscroft JA, Murray AJ(2013) Mitochondrial respiration in heart and soleus of ob/ob mice. Mitochondr Physiol Network 18.08. | LEAK OXPHOS | F N S | Permeabilized tissue | Mouse | Heart Skeletal muscle |
| Dzialowski 2013 Abstract MiP2013 | 2013 | Dzialowski EM, Ream S, Duquaine A, Sirsat TS, Goy Sirsat SK (2013) Mitochondrial function and the development of endothermy in the precocial Pekin duck (Anas pekin). Mitochondr Physiol Network 18.08. | LEAK OXPHOS ET | F N S NS | Intact organism Permeabilized tissue | Birds | Skeletal muscle |
| Chicco 2013 Abstract MiP2013 | 2013 | Chicco AJ, Le CH, Schlater A, Kanatous S (2013) Comparative muscle mitochondrial physiology of the northern elephant seal. Mitochondr Physiol Network 18.08. | LEAK OXPHOS ET | F N Other combinations | Permeabilized tissue | Human Other mammals | Skeletal muscle |
| Gnaiger 2013 Abstract MiP2013 | 2013 | Gnaiger E, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet J, Christiansen M, Helge JW, Saltin B, Boushel R (2013) Biochemical coupling efficiency in permeabilized fibers from arm and leg muscle in Inuit versus Caucasians: A functional test of the uncoupling hypothesis in Greenland. Mitochondr Physiol Network 18.08. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Human | Skeletal muscle |
| Gnaiger 2012 Abstract-FEPS-Santiago de Compostela | 2012 | Gnaiger E (2012) Aging and mitochondrial physiology. The effect of exercise and caloric balance on oxidative phosphorylation (OXPHOS). Abstract FEPS, Santiago de Compostela, Spain. Symposium: Advances in Aging and Mitochondria Research. September 08-12. | F N S NS | Human Horse | |||
| Jacobs 2012 Abstract Bioblast | 2012 | Jacobs R, Lundby C (2012) Mitochondria express enhanced quality as well as quantity in parallel with aerobic fitness across recreationally active individuals up to elite athletes. Mitochondr Physiol Network 17.12. | LEAK OXPHOS ET | F N S NS | Permeabilized cells | Human | Skeletal muscle |
| Pesta 2011Abstract Mitochondrial Medicine-Training | 2011 | Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Mitochondrial improvements after strength, endurance, and intermittend hypoxic training in sedentary humans. A respiratory study on permeabilized muscle fibers. Abstract Mitochondrial Medicine Chicago. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
| Gnaiger 2011 Abstract-Berlin | 2011 | Gnaiger E (2011) Fewer mitochondria - mitochondrial 'fever': Mitochondrial physiology and capacity of oxidative phosphorylation in active and sedentary life styles. Abstract Targeting Mitochondria Berlin. | F N S NS | Human | |||
| Pesta 2010 MiP Abstract | 2010 | Pesta D, Faulhaber M, Burtscher M, Gnaiger E, Schocke M (2010) Investigation of muscle metabolism of the M. quadriceps via 31P MRS and high-resolution respirometry in connection with 10 weeks of strength and endurance training in normoxia and hypoxia. MiP2010. | LEAK OXPHOS ET | F N S NS | Human | ||
| Gnaiger 2005 Abstract MiP2005 | 2005 | Gnaiger Erich, Wright-Paradis C, Sondergaard H, Lundby C, Calbet Jose AL, Saltin Bengt, Helge J, Boushel R (2005) High-resolution respirometry in small biopsies of human muscle: correlations with body mass index and age. MiP2005. | OXPHOS ET | F N CIV NS | Permeabilized tissue | Human | Skeletal muscle |
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