Glutamate-aspartate carrier

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Bioblasts - Richard Altmann and MiPArt by Odra Noel
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Glutamate-aspartate carrier

Description

The glutamate-aspartate carrier catalyzes the electrogenic antiport of glutamate- +H+ for aspartate-. It is an important component of the malate-aspartate shuttle in many mitochondria. Due to the symport of glutamate- + +H+, the glutamate-aspartate antiport is not electroneutal and may be impaired by uncoupling. Aminooxyacetate is an inhibitor of the glutamate-aspartate carrier.


Reference: Gnaiger 2012 MitoPathways


MitoPedia topics: Substrate and metabolite