Halestrap AP

From Bioblast
Name Halestrap Andrew P, Prof.
Institution Department of Biochemistry

School of Med. Sciences

University of Bristol

Address University Walk, BS8 1TD
City Bristol
State/Province
Country United Kingdom
Email a.halestrap@bristol.ac.uk
Weblink
O2k-Network Lab UK Bristol Halestrap AP


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Publications

 PublishedReference
Knapp-Wilson 2021 bioRxiv2021Knapp-Wilson A, Pereira GC, Buzzard E, Richardson A, Corey RA, Neal C, Verkade P, Halestrap AP, Gold VAM, Kuwabara P, Collinson I (2021) Maintenance of complex I and respiratory super-complexes by NDUF-11 is essential for respiratory function, mitochondrial structure and health in C. elegans. bioRxiv doi: https://doi.org/10.1101/2021.01.06.425530.
Knapp-Wilson 2021 J Cell Sci2021Knapp-Wilson A, Pereira GC, Buzzard E, Ford HC, Richardson A, Corey RA, Neal C, Verkade P, Halestrap AP, Gold VAM, Kuwabara PE, Collinson I (2021) Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health. J Cell Sci 134:jcs258399. doi: 10.1242/jcs.258399
Pereira 2020 PLoS One2020Pereira GC, Lee L, Rawlings N, Ouwendijk J, Parker JE, Andrienko TN, Henley JM, Halestrap AP (2020) Hexokinase II dissociation alone cannot account for changes in heart mitochondrial function, morphology and sensitivity to permeability transition pore opening following ischemia. PLoS One 15:e0234653.
Andrienko 2017 J Mol Cell Cardiol2017Andrienko TN, Pasdois P, Pereira GC, Ovens MJ, Halestrap AP (2017) The role of succinate and ROS in reperfusion injury - a critical appraisal. J Mol Cell Cardiol 110:1-14. doi: 10.1016/j.yjmcc.2017.06.016
Hansson 2015 Eur J Pharmacol2015Hansson MJ, Llwyd O, Morin D, de Paulis D, Arnoux T, GouarnΓ© C, Koul S, Engblom H, Bordet T, Tissier R, Arheden H, Erlinge D, Halestrap AP, Berdeaux A, Pruss RM, Schaller S (2015) Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury. Eur J Pharmacol 760:7-19.
Littlejohns 2014 PLoS One2014Littlejohns B, Pasdois P, Duggan S, Bond AR, Heesom K, Jackson CL, Angelini GD, Halestrap AP, Suleiman MS (2014) Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury. PLoS One 9:e100579.
Pasdois 2012 J Am Heart Assoc2012Pasdois P, Parker JE, Halestrap AP (2012) Extent of mitochondrial hexokinase II dissociation during ischemia correlates with mitochondrial cytochrome c release, reactive oxygen species production, and infarct size on reperfusion. J Am Heart Assoc 2:e005645.
Pasdois 2011 Biochem J2011Pasdois P, Parker JE, Griffiths EJ, Halestrap AP (2011) The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia. Biochem J 436:493-505.
Hildyard 2003 Biochem J2003Hildyard JC, Halestrap AP (2003) Identification of the mitochondrial pyruvate carrier in Saccharomyces cerevisiae. Biochem J 374: 607-611.
Griffiths 1995 Biochem J1995Griffiths EJ, Halestrap AP (1995) Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion. Biochem J 307:93-98.
Halestrap 1986 Biochem J1986Halestrap AP, Dunlop JL (1986) Intramitochondrial regulation of fatty acid beta-oxidation occurs between flavoprotein and ubiquinone. A role for changes in the matrix volume. Biochem J 239:559-65. https://doi.org/10.1042/bj2390559

Abstracts

 PublishedReference
Pereira 2015 Abstract MiPschool London 20152015Ischaemia but not in vitro dissociation of heart mitochondrial-bound hexokinase II affects organelle physiology and morphology.
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