Hochachka PW

From Bioblast
Name Hochachka Peter W, Prof. PhD (9 Mar 1937 – 16 Sep 2002)
Peter W Hochachka 1996

University of British Columbia

Address ,
City Vancouver
State/Province British Columbia (BC)
Country Canada
O2k-Network Lab

Labels: Field of research: Basic 


Hochachka 2002 Oxford Univ Press2002Hochachka PW, Somero GN (2002) Biochemical adaptation: mechanism and process in physiological evolution. Oxford Univ Press, New York: 466 pp.
McClelland 1998 Proc Natl Acad Sci U S A1998McClelland GB, Hochachka PW, Weber JM (1998) Carbohydrate utilization during exercise after high-altitude acclimation: a new perspective. Proc Natl Acad Sci U S A 95:10288-93.
Hochachka 1998 Proc Natl Acad Sci U S A1998Hochachka PW, Gunga HC, Kirsch K (1998) Our ancestral physiological phenotype: an adaptation for hypoxia tolerance and for endurance performance? Proc Natl Acad Sci U S A 95:1915-20.
Buck 1993 Am J Physiol Regul Integr Comp Physiol1993Buck LT, Hochachka PW, SchΓΆn A, Gnaiger E (1993) Microcalorimetric measurement of reversible metabolic suppression induced by anoxia in isolated hepatocytes. Am J Physiol Regul Integr Comp Physiol 265:R1014-9.
Hochachka 1993 Hypoxia1993Hochachka PW (1993) Adaptability of metabolic efficiencies under chronic hypoxia in man. In: Surviving Hypoxia: Mechanisms of Control and Adaptation. Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) CRC Press, Boca Raton, Ann Arbor, London, Tokyo: 127-135.
Hochachka 1993 Surviving hypoxia1993Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) (1993) Surviving hypoxia: mechanisms of control and adaptation. CRC Press, Boca Raton, Ann Arbor, London, Tokyo:570 pp.
Moyes 1992 Am J Physiol1992Moyes CD, Schulte PM, Hochachka PW (1992) Recovery metabolism of trout white muscle: role of mitochondria. Am J Physiol 262:R295-304.
Schulte 1992 J Exp Biol1992Schulte PM, Moyes CD, Hochachka PW (1992) Integrating metabolic pathways in post-exercise recovery of white muscle. J Exp Biol 166:181-95.
Matheson 1991 J Appl Physiol1991Matheson GO, Allen PS, Ellinger DC, Hanstock CC, Gheorghiu D, McKenzie DC, Stanley C, Parkhouse WS, Hochachka PW (1991) Skeletal muscle metabolism and work capacity: a 31P-NMR study of Andean natives and lowlanders. J Appl Physiol 70:1963-76.
Moyes 1990 Am J Physiol1990Moyes CD, Buck LT, Hochachka PW (1990) Mitochondrial and peroxisomal fatty acid oxidation in elasmobranchs. Am J Physiol 258:R756-62.
Moyes 1989 J Exp Biol1989Moyes CD, Buck LT, Hochachka PW, Suarez RK (1989) Oxidative properties of carp red and white muscle. J Exp Biol 143:321-31.
Moyes 1988 Am J Physiol1988Moyes CD, Buck LT, Hochachka PW (1988) Temperature effects on pH of mitochondria isolated from carp red muscle. Am J Physiol 254:R611-5.
Dobson 1988 Am J Physiol1988Dobson GP, Parkhouse WS, Weber JM, Stuttard E, Harman J, Snow DH, Hochachka PW (1988) Metabolic changes in skeletal muscle and blood of greyhounds during 800-m track sprint. Am J Physiol 255:R513-19.
Weber 1987 Am J Physiol1987Weber JM, Parkhouse WS, Dobson GP, Harman JC, Snow DH, Hochachka PW (1987) Lactate kinetics in exercising Thoroughbred horses: regulation of turnover rate in plasma. Am J Physiol 253: R896-R903.
Weber 1987b Am J Physiol1987Weber JM, Dobson GP, Parkhouse WS, Wheeldon D, Harman JC, Snow DH, Hochachka PW (1987) Cardiac output and oxygen consumption in exercising Thoroughbred horses. Am J Physiol 253:R890-5.
Hochachka 1984 Princeton Univ Press1984Hochachka PW, Somero GN (1984) Biochemical adaptation. Princeton Univ Press, New Jersey: 537 pp.
Storey 1979 Can J Zool1979Storey KB, Storey JM, Johansen K, Hochachka PW (1979) Octopine metabolism in Sepia officinalis: effect of hypoxia and metabolite loads on the blood levels of octopine and related compounds. Can J Zool 57:2331-6.
Hochachka 1976 Eur J Appl Physiol Occup Physiol1976Hochachka PW, Dressendorfer RH (1976) Succinate accumulation in man during exercise. Eur J Appl Physiol Occup Physiol 35:235-42. doi: 10.1007/BF00423282
Hochachka 1975 Science1975Hochachka PW, Storey KB (1975) Metabolic consequences of diving in animals and man. Science 187:613-21. doi: 10.1126/science.163485


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Peter Hochachka from Innsbruck 1991 to Peru 1996

International Summer Course Innsbruck. Calorimetry, respirometry, and biological energetics: from the organelle to the organism (1991) Peter Hochachka presented an β€œOverview of metabolic suppression in defence against environmental stress: the hypoxia example” - a 4.5 h talk. On the next days, full morning lectures were continued by Steve Hand (Anabolic and catabolic arrest during invertebrate dormancy) and Erich Gnaiger (Muscle and mitochondria at rest and work: Adenylate control and the concept of chemical reaction pressure). During the evening party of the last day, Peter’s enthusiasm caught everybody in an unforgettable slide show: A global perspective of environmental physiology – in the spirit of Kjell Johansen’s β€œThe world as a laboratory”. The marathon lectures received an overwhelmingly positive response by the 55 students. With this in mind, Peter invited me to the World Congress of High Altitude Medicine and Physiology in Cusco (telephone call at 3 am), with the condition to join a pre-conference workshop in Machu Picchu with five participants: In a 4.5 h walk&talk up the Inca trail I talked thermodynamic efficiency [1] which he enjoyed (photo by EG), whereas Peter expanded on biochemical efficiency in Quechuas on the way down [2] which was definitely more β€˜efficient’. Much later I received a surprising and disturbing letter, where Peter suggested a personal contract to be made: he or me – whoever may survive the other – should organize an event to commemorate the other. For more than a decade I kept this in mind. Outstanding events were organized in Peter’s name. I did not feel prepared to add something living up to his expectations. The emergence of a new β€˜Comparative Mitochondrial Physiology’ is just right to fulfill my contract with Peter.

Innsbruck, Sep 2013 - Erich Gnaiger
  1. Gnaiger E (1993) Efficiency and power strategies under hypoxia. Is low efficiency at high glycolytic ATP production a paradox? In: Surviving hypoxia: Mechanisms of control and adaptation. Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) CRC Press, Boca Raton, Ann Arbor, London, Tokyo: 77-109.
  2. Hochachka PW (1993) Adaptability of metabolic efficiencies under chronic hypoxia in man. Ibid: 127-135.

Peter Hochachka

Peter Hochachka Memorial Session at MiP2013

Peter Hochachka: Adventures in Biochemical Adaptation

Somero G, Suarez RK (2005) Annu Rev Physiol 67: 25-37.

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