From Bioblast

high-resolution terminology - matching measurements at high-resolution



Molecular hydrogen H2 is a constituent of the air with a volume fraction of 0.00005. It is a colorless and odorless gas with a molecular mass of 2.016. Its pharmacological potential and effects on mitochondrial metabolism are discussed in various publications without complete evidence on the underlying mechanisms.

Abbreviation: H2


 Was published in yearReference
Tian 2021 Front Physiol2021Tian Yan, Zhang Yafang, Wang Yu, Chen Yunxi, Fan Weiping, Zhou Jianjun, Qiao Jing, Wei Youzhen (2021) Hydrogen, a novel therapeutic molecule, regulates oxidative stress, inflammation, and apoptosis. Front Physiol 12:2281. https://doi.org/10.3389/fphys.2021.789507.
Ohta 2021 Curr Pharm Des2021Ohta S (2021) Direct targets and subsequent pathways for molecular hydrogen to exert multiple functions: focusing on interventions in radical reactions. Curr Pharm Des 27:583-4. doi: 10.2174/138161282705210211144515
Gvozdjakova 2020 Can J Physiol Pharmacol2020Gvozdjakova A, Kucharska J, Kura B, Vancova O, Rausova Z, Sumbalova Z, Ulicna O, Slezak J (2020) A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats. Can J Physiol Pharmacol 98: 29–34. doi: 10.1139/cjpp-2019-0281.
Mikami 2019 Can J Physiol Pharmacol2019Mikami T, Tano K, Lee H, Lee H, Park J, Ohta F, LeBaron TW, Ohta S (2019) Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study 1. Can J Physiol Pharmacol 97:857-62. doi: 10.1139/cjpp-2019-0059
Ohta 2015 Methods Enzymol2015Ohta S (2015) Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications. Methods Enzymol 555:289-317. doi: 10.1016/bs.mie.2014.11.038
Zhai 2014 Med Gas Res2014Zhai X, Chen X, Ohta S, Sun X (2014) Review and prospect of the biomedical effects of hydrogen. Med Gas Res 4:19. doi: 10.1186/s13618-014-0019-6
Ohsawa 2007 Nat Med2007Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S (2007) Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 13:688-94. doi: 10.1038/nm1577.


Electrolytic production of H2 gas: Oxia

MitoPedia topics: Substrate and metabolite 

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