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Kucera Otto

From Bioblast

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BEC 2020.1 Mitochondrial physiology
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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Kucera Otto

MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1


Name Kucera Otto, Assoc. Prof., M.D., PhD.
Otto Kucera

Faculty of Medicine in Hradec Kr├ílov├ę,

Charles University in Prague, CZ

Address Šimkova 870, 500 38
City Hradec Kralove
Country Czech Republic
O2k-Network Lab CZ Hradec Kralove Cervinkova Z



Endlicher 2021 Physiol Res2021Endlicher R, Drahota Z, Ku─Źera O, ─îervinkov├í Z (2021) Age-dependent changes in the function of mitochondrial membrane permeability transition pore in rat liver mitochondria. Physiol Res 70:905-11.
Stankova 2021 Int J Mol Sci2021Sta┼łkov├í P, Ku─Źera O, Peterov├í E, Elkalaf M, Rychtrmoc D, Melek J, Podhola M, Zub├í┼łov├í V, ─îervinkov├í Z (2021) Western diet decreases the liver mitochondrial oxidative flux of succinate: insight from a murine NAFLD model.
Stankova 2020 Int J Mol Sci2020Sta┼łkov├í P, Ku─Źera O, Peterov├í E, Lotkov├í H, Maseko TE, No┼żi─Źkov├í K, ─îervinkov├í Z (2020) Adaptation of mitochondrial substrate flux in a mouse model of nonalcoholic fatty liver disease. Int J Mol Sci 21:E1101.
BEC 2020.1 doi10.26124bec2020-0001.v12020Gnaiger E et al ÔÇĽ MitoEAGLE Task Group (2020) Mitochondrial physiology.
Mezera 2016 Oxid Med Cell Longev2016Mezera V, Endlicher R, Kucera O, Sobotka O, Drahota Z, Cervinkova Z (2016) Effects of epigallocatechin gallate on tert-butyl hydroperoxide-induced mitochondrial dysfunction in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 7573131:8pp.
Kucera 2016 Drug Chem Toxicol2016Ku─Źera O, Endlicher R, Rychtrmoc D, Lotkov├í H, Sobotka O, ─îervinkov├í Z (2016) Acetaminophen toxicity in rat and mouse hepatocytes in vitro. Drug Chem Toxicol 40:448-56.
Sobotka 2016 J Bioenerg Biomembr2016Sobotka O, Endlicher R, Drahota Z, Ku─Źera O, Rychtrmoc D, Raad M, Hakeem K, ─îervinkov├í Z (2016) Impaired mitochondrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes. J Bioenerg Biomembr 48:363-73.
Cahova 2016 Am J Physiol Gastrointest Liver Physiol2016Cahova M, Palenickova E, Dankova H, Sticova E, Burian M, Drahota Z, Cervinkova Z, Kucera O, Gladkova C, Stopka P, Krizova J, Papackova Z, Oliyarnyk O, Kazdova L (2016) Metformin prevents ischemia reperfusion-induced oxidative stress in the fatty liver by attenuation of reactive oxygen species formation. Am J Physiol Gastrointest Liver Physiol 309:G100-11.
Kucera 2015 Oxid Med Cell Longev2015Kucera O, Mezera V, Moravcova A, Endlicher R, Lotkova H, Drahota Z, Cervinkova Z (2015) In vitro toxicity of epigallocatechin gallate in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 2015:476180.
Sobotka 2015 Physiol Res2015Sobotka O, Drahota Z, Ku─Źera O, Endlicher R, Rauchov├í H, ─îervinkov├í Z (2015) The effect of ╬▒-tocopheryl succinate on succinate respiration in rat liver mitochondria. Physiol Res 64 Suppl 5:S609-15.
Garnol 2014 Physiol Res2014Garnol T, Endlicher R, Ku─Źera O, Drahota Z, Cervinkov├í Z (2014) Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4.
Kucera 2014 Oxid Med Cell Longev2014Ku─Źera O, Endlicher R, Rou┼íar T, Lotkov├í H, Garnol T, Drahota Z, Cervinkov├í Z (2014) The effect of tert-butyl hydroperoxide-induced oxidative stress on lean and steatotic rat hepatocytes in vitro. Oxid Med Cell Longev 2014:752506.
Kucera 2012 J Gastroenterol Hepatol2012Kucera O, Rousar T, Stankova P, Hanackova L, Lotkova H, Podhola M, Cervinkova Z (2012) Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen. J Gastroenterol Hepatol 27:323-30.
Lotkova 2011 Gen Physiol Biophys2011Lotkov├í H, Sta┼łkov├í P, Rou┼íar T, Ku─Źera O, Kohoutek L, Mi─Źuda S, Br─Ź├íkov├í E, Kolouchov├í G, Cervinkov├í Z (2011) Deteriorating effect of fluvastatin on the cholestatic liver injury induced by bile duct ligation in rats. Gen Physiol Biophys 30:66-74.
Kucera 2011 Physiol Res2011Ku─Źera O, Garnol T, Lotkov├í H, Sta┼łkov├í P, Mazurov├í Y, Hroch M, Bolehovsk├í R, Rou┼íar T, ─îervinkov├í Z (2011) The effect of rat strain, diet composition and feeding period on the development of a nutritional model of non-alcoholic fatty liver disease in rats. Physiol Res 60:317-28.
Kucera 2011 Int J Exp Pathol2011Ku─Źera O, Lotkov├í H, Sta┼łkov├í P, Podhola M, Rou┼íar T, Mezera V, Cervinkov├í Z (2011) Is rat liver affected by non-alcoholic steatosis more susceptible to the acute toxic effect of thioacetamide?. Int J Exp Pathol 92:281-9.
Stankova 2010 Toxicol In Vitro2010Sta┼łkov├í P, Ku─Źera O, Lotkov├í H, Rou┼íar T, Endlicher R, Cervinkov├í Z (2010) The toxic effect of thioacetamide on rat liver in vitro. Toxicol In Vitro 24:2097-2103.
Lotkova 2009 Acta Vet Brno2009Lotkov├í H, Ku─Źera O, Rou┼íar T, Endlicher R, K┼Öiv├íkov├í P, Garnol T, ─îervinkov├í Z (2009) Effect of S-adenosylmethionine on Acetaminophen-induced toxic injury of rat hepatocytes in vitro. Acta Vet Brno 78:603-13.
Cervinkova 2009 Arch Toxicol2009Cervinková Z, Kriváková P, Lábajová A, Rousar T, Lotková H, Kucera O, Endlicher R, Cervinka M, Drahota Z (2009) Mechanisms participating in oxidative damage of isolated rat hepatocytes. Arch Toxicol 83:363-72.
Cervinkova 2007 Altern Lab Anim2007Cervinkova Z, Lotkova H, Krivaikova P, Rousar T, Kucera O, Tichy L, Cervinka M, Drahota Z (2007) Evaluation of mitochondrial function in isolated rat hepatocytes and mitochondria during oxidative stress. Altern Lab Anim 35:353-61.
Drahota 2005 Physiol Res2005Drahota Z, Krivakova P, Cervinkova Z, Kmonickova E, Lotkova H, Kucera O, Houstek J (2005) Tert-butyl hydroperoxide selectively inhibits mitochondrial respiratory-chain enzymes in isolated rat hepatocytes. Physiol Res 54:67-72.


Stankova 2018 MiP20182018
Pavla Krivakova-Stankova
Impact of western diet on energy metabolism in mouse liver.
Rodriguez-Hernandez 2018 Free Radic Biol Med2018Rodriguez-Hern├índez A, Sta┼łkov├í P, Gonz├ílez R, De la Rosa AJ, ├ülamo-Martinez JM, Marin-G├│mez LM, Sobotka O, Ku─Źera O, Padillo FJ, ─îervinkov├í Z, Muntan├ę J (2018) The alteration of mitochondrial function is associated with the induction of endoplasmic reticulum stress autophagy and apoptosis by Sorafenib in liver cancer cells. Free Radic Biol Med.
Nozickova 2017 MiP20172017
Katerina Nozickova
The early adaptation of rat liver mitochondria to high fat diet.
Sobotka 2017 Abstract MITOEAGLE Barcelona2017
The effect of 24 weeks of high-fat and high-cholesterol diet on rat liver mitochondria. Sobotka_Presentation
Sobotka 2017 MiP20172017
Ondrej Sobotka
Metabolic changes in rat liver mitochondria during the development of liver steatosis.
Endlicher 2017 MiP20172017
Rene Endlicher
Age-related changes in isolated mitochondria from rat liver.
Kovalcikova 2017 MiP20172017
Kovalcikova Jana
Mitochondrial protein TMEM70: key role in the biogenesis of ATP synthase verified in a mouse knockout model.
Kucera 2017 MiP20172017
Otto Kucera
Commonly used models of non-alcoholic fatty liver disease (NAFLD).
Stankova 2017 MiP20172017
Pavla Stankova
Isolation of rat liver mitochondria for bioenergetic studies.
Sobotka 2016 Abstract IOC1162016Sobotka O, Kucera Otto, Stankova P, Endlicher R, Nozickova K, Banni A, Cervinkova Z (2016) Mitochondrial respiration in fatty liver. Mitochondr Physiol Network 21.11
Rousarova 2015 Abstract MiPschool London 20152015Estimation of ROS production in isolated mitochondria after treatment with an acetaminophen metabolite.
Cervinkova 2012 Abstract Bioblast2012Cervinkova Z, Stankova P, Cervinka M, Kucera O, Drahota Z (2012) Evaluation of mitochondrial functions ÔÇô an important tool for experimental hepatology. Mitochondr Physiol Network 17.12.

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