LV Riga Makrecka-Kuka M

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LV Riga Makrecka-Kuka M

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Latvian Institute of Organic Synthesis

Laboratory of Pharmaceutical Pharmacology

Address Aizkraukles Street 21, LV-1006
City Riga
State/Prov
Country Latvia
Weblink http://www.osi.lv/en/
Contact Makrecka-Kuka Marina
Team Liepins Edgars, Volska Kristine, Stelfa Gundega
Team previous
Status 5 Power-O2k 2015-
Oroboros Events MiPschool 2018, MitoEAGLE 2018 LV, MitoEAGLE 2017 CZ, MitoEAGLE 2017 ES, MitoEAGLE 2016 IT, MitoFit Science Camp 2016, IOC109, IOC105, IOC95, MiP2014, MiP2013
Topics


O2k-Publications

 PublishedReference
MiPNet25.11 IOC148 Riga LV2020-10-07
O2k-Network
Riga, LV, 2020-10-07. Pre-Conference O2k-Workshop on measurement of mitochondrial functionality in cardiac tissues IOC148.
Allen 2020 Commun Biol2020Allen ME, Pennington ER, Perry JB, Dadoo S, Makrecka-Kuka M, Dambrova M, Moukdar F, Patel HD, Han X, Kidd GK, Benson EK, Raisch TB, Poelzing S, Brown DA, Shaikh SR (2020) The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats. Commun Biol 3:389.
Makrecka-Kuka 2020 Cardiovasc Drugs Ther2020Makrecka-Kuka Marina, Korzh Stanislava, Videja Melita, Vilks Karlis, Cirule Helena, Kuka Janis, Dambrova Maija, Liepinsh Edgars (2020) Empagliflozin protects cardiac mitochondrial fatty acid metabolism in a mouse model of diet-induced lipid overload. Cardiovasc Drugs Ther [Epub ahead of print].
Liepinsh 2020 Physiol Rep2020Liepinsh E, Makarova E, Plakane L, Konrade I, Liepins K, Videja M, Sevostjanovs E, Grinberga S, Makrecka-Kuka M, Dambrova M (2020) Low-intensity exercise stimulates bioenergetics and increases fat oxidation in mitochondria of blood mononuclear cells from sedentary adults. Physiol Rep 8:e14489.
Perry 2019 J Mol Cell Cardiol2019Perry JB, Davis GN, Allen ME, Makrecka-Kuka M, Dambrova M, Grange RW, Shaikh SR, Brown DA (2019) Cardioprotective effects of idebenone do not involve ROS scavenging: Evidence for mitochondrial complex I bypass in ischemia/reperfusion injury. J Mol Cell Cardiol 135:160-171.
Makrecka-Kuka 2017 Toxicol Lett2017Makrecka-Kuka M, Volska K, Antone U, Vilskersts R, Grinberga S, Bandere D, Liepinsh E, Dambrova M (2017) Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria. Toxicol Lett 267:32-8.
Liepinsh 2016 Biochem J2016Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M (2016) Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem J 473:1191-202.
MiPNet20.16 IOC105 Riga2015-08-27
O2k-Network
Riga LV, 2015 Aug 27. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry - innovabalt, IOC105.
Makrecka-Kuka 2015 Biomolecules2015
O2k-Protocols contents
Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. Biomolecules 5:1319-38.

O2k-Abstracts

 PublishedReference
Stelfa 2018 MiP20182018
MiPsociety
Neuroprotective compound R-phenibut protects brain mitochondria against anoxia-reoxygenation damage in vitro.
Kuka 2018 MiP20182018
MiPsociety
The discovery of methyl-GBB - acylcarnitine lowering as an effective strategy to treat cardiometabolic diseases.
Volska 2018 MiP20182018
Kristina Volska
The mechanisms of long-chain acylcarnitine accumulation during ischemia.
Kidere 2018 MiPschool Tromso E22018
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the OXPHOS system: control sample with glutamate metabolism defect.
Makrecka-Kuka 2018 MiPschool Tromso E12018
Marina Makrecka-Kuka
Cardiac fatty acid oxidation: from in vitro to in vivo.
Kidere 2018 MiP20182018
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the effect of the mtDNA mutations on the OXPHOS system.
Makrecka-Kuka 2017 MiP20172017
Marina Makrecka-Kruka
Heart, brain and kidneys: who will survive? Tissue-specific changes in mitochondrial function in the experimental model of endotoxemia.

IOC105 O2k-Workshop 2015-08-27


Visiting scientist in the Oroboros O2k-Laboratory

O2k-Network
Marina Makrecka-Kuka: Visiting scientist at the Oroboros O2k-Laboratory from March 12 to 29 2018
Kristine Volska: Visiting scientist at the Oroboros O2k-Laboratory from March 01 to April 01 2016
Marina Makrecka-Kuka: Visiting scientist at the Oroboros O2k-Laboratory within the framework of FP7 from August until October 2014