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Lancaster 2002 Biochim Biophys Acta

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Publications in the MiPMap
Lancaster CR (2002) Succinate:quinone oxidoreductases: an overview. Biochim Biophys Acta 1553:1-6. https://doi.org/10.1016/s0005-2728(01)00240-7

Β» PMID: 11803013 Open Access

Lancaster CR (2002) Biochim Biophys Acta

Abstract: Succinate:quinone oxidoreductases (SQORs, EC 1.3.5.1) are enzymes that couple the two-electron oxidation of succinate to fumarate (reaction 1) to the two-electron reduction of quinone to quinol (reaction 2):

succinate β†’ fumarate + 2H+ + 2e- (1)

quinone + 2H+ + 2e- β†’ quinol (2)

β€’ Bioblast editor: Gnaiger E

Lancaster 2002 Biochim Biophys Acta.png
The 2H+ in reaction 1,
succinate β†’ fumarate + 2H+ + 2e- (1)
has an entirely different meaning as the H+ in NADH + H+ shown in Figure 1a. In this figure, fumarate + 2H+ shown besides NADH + H+ is ambiguous [1].
1. Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. MitoFit Preprints 2023.3. https://doi.org/10.26124/mitofit:2023-0003.v4


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Enzyme: Complex II;succinate dehydrogenase