McCurdy 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
|Cannon 2015 Fatty Acid Oxidation O2k-Network Discussion Forum|
McCurdy CE (2015)
We have had good success using the Octanoylcarnitine at the recommended dose of 0.2mM in SUIT protocols with PMG and with just GM. Respiration increases with addition of ADP and subsequent substrate additions. We have also used palmitoylcarnitine at a conc of 0.025 -0.05mM with mixed success. Often there is no or little stable increase in ADP stimulated respiration and requires addition of pyr and/or Glut. We primarily test nonhuman primate (japanses macaque) permeabilized muscle fibers.
Organism: Other mammals Tissue;cell: Skeletal muscle Preparation: Permeabilized tissue
Coupling state: OXPHOS Pathway: F, N
Octanoylcarnitine + Palmitoylcarnitine