MiP2023 Obergurgl AT

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MiP2023 Obergurgl AT

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MiPconference
Obergurgl AT. 2023 Jul 27-30. 15th MiPconference: Bioenergetics Communications on mitObesity and Healthy Aging. - cover-to-cover following the MiPschool Obergurgl 2023

» Book of abstracts: MiP2023 Bioenerg Commun

Mitochondrial Physiology Society (2023-07-27) MitoGlobal

Abstract: MiP2023, Obergurgl, Austria, 2023.

mitObesity

Feedback from participants

  • The MiP2023 conference was hands down the best conference I have ever attended. - Granata Cesare, DE
  • Thank you again for the wonderful event that was MIPSchool and the MIPconference. It was a wonderful experience for me, all the contact with different researchers, such as Anthony Moore, Leonid Sazanov, Erika Fernández-Vizarra, among others. As well for your hospitality and reception. THANK YOU VERY MUCH FOR EVERYTHING. 😊😊😊 - Othonicar Murilo F, BR
  • The conference was wonderful as usual - thanks so much for all you do to make these events such a success! :) It was great to catch up with you [Verena], Erich and my other friends in the MiP community. I'm already looking forward to the next event, but back to regular work first! - Chicco Adam J, US
  • The lectures dealt with a highly relevant topic from the perspective of mitochondrial physiology, a highly specialized subject but with a very practical aspect (diagnostic tools, metabolic adaptations following therapeutic interventions, etc.). The atmosphere was very friendly and, as at every MiPConference, I met new scientists and made new friends. - Votion Dominique-Marie, BE
  • Congratulations on another great meeting. The quality of the presentations was outstanding. - Molina Anthony JA, US
  • I wanted to send a special thank you for the outstanding organization and hospitality at the conference. The time and efforts you dedicated to make this a successful event resulted in a scientifically stimulating symposium and a wonderful social and nature experiences. Both Linsey and I felt personally welcomed to Obergurgl and to the conference and enjoyed every moment. Shirihai Orian, US
  • The MiPconference 2023 was excellent and I was pleased to participate. - Hand Steven C, US
  • I really liked the "walk and talk" sessions and overall environment and discussions. - Anonymous participant
  • The networking was great! - Anonymous participant
  • I enjoyed the sessions on Lifestyle and Mitoalterations in Obesity as well as on Nutrition and Lifestyle in MitObesity. - Anonymous participant
  • The topics of Mitoalterations associated with lifestyle, obesity or by nutrition were great! - Anonymous participant


Question Rating (average) 1-5
In how far were your interests covered in the MiPconference? 1 (not covered) to 5 (all interests covered) 4.6
Presentation of lectures in terms of content: 1 (not understandable) to 5 (very understandable) 4.6
Presentation of lectures in terms of language: 1 (not understandable) to 5 (very understandable) 4.6
What is your overall rating of the MiPconference 2023 from 1 (poor) to 5 (excellent)? 4.6

Impressions from MiP2023

Venue

Obergurgl venue.jpg
University Center Obergurgl
Gaisbergweg 5
6456 Obergurgl
Tyrol, Austria


  • Support for the MiPconference 2023 is acknowledged (alphabetical order):
  • Hamilton Logo.jpg
  • Logo OROBOROS INSTRUMENTS.jpg
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  • Tirol sat lining RGB.png
  • We invite cooperating scientific societies and institutions to cooperate and support the MiPconference 2023.


    Presentation guidelines

    Oral
    Timing
    • Duration for invited speakers: 20 min (+5 min discussion)
    • Duration oral presentations selected from abstracts: 10 min (+5 min discussion)
    • Aspect ratio for slides: 16:9
    • Use either PowerPoint or Keynote
    • A laptop for your presentation is provided
    • If you work with a Mac please bring your own computer
    • Ensure you bring an adapter for your device with HDMI connection, VGA to HDMI is provided
    • Please make sure you do not go overtime
    • Media check to hand in your slides in the morning of the conference is possible
    Posters
    • Please bring your poster in size A0, portrait.
    BEC Special Issue
    https://www.bioenergetics-communications.org/index.php/bec
    We invite original articles to be published in a special issue of Bioenergetics Communications on ‘mitObesity and Healthy Aging’:
    » BEC author guidelines


    Program

    The topic of the 15th MiPconference is: Bioenergetics Communications on mitObesity and Healthy Aging.
    Furthermore, the General Assembly of the MiPsociety will take place during the conference.
    Program pdf

    pdf

    Program-at-a-glance

    Programme at a glance 2023.PNG

    2023-Jul-27 Thursday Arrival


    17:30 Welcome reception
    19:00 Dinner
    20:30 Opening
    20:30 – 21:30 Erich Gnaiger: From globesity to mitObesity.


    2023-Jul-28 Friday


    08:30 Session A1. Lifestyle and mitoalterations in obesity
    Session chairs: Verena Laner and Orian Shirihai


    08:30 – 08:55 Anthony Molina: Targeting exercise intolerance in older, obese, heart failure patients.
    08:55 – 09:10 Heather Petrick: Age- and sex-related differences in mitochondrial ADP sensitivity in human skeletal muscle.
    09:10 – 09:25 Ana Valencia: T-cell mitochondria exhibit a functional decline with obesity that is aggravated by weight loss.
    09:25 – 09:50 Tal Yardeni: The host immune system and the gut microbiota are regulated by the mitochondrial DNA.

    09:50 Coffee/tea break

    10:25 Session A2. Exercise, training and hypoxia
    Session chairs: Dominique-Marie Votion and Alexander Karabatsiakis

    10:25 – 10:50 Steen Larsen: Mitochondrial adaptations to weight loss – lifestyle, surgery or medication.
    10:50 – 11:05 Henver Brunetta: Chronic aerobic training reverts the negative effects of high-fat high-sucrose diet on the left ventricle of adipocyte-specific DICER knockout mice in association with improved mitochondrial function.
    11:05 – 11:20 Daniel Sadler: Early life exercise training counters metabolic perturbations imparted by low parental cardiorespiratory fitness.
    11:20 – 11:45 Bengt Kayser: Obesity and hypoxia: from etiology to therapy.
    11:45 – 12:00 Steven Hand: Oxidative stress and repetitive metabolic transitions: Challenges due to lifestyle of invertebrate extremophiles.

    12:00 - 15:30 Walk & Talk

    15:30 Session A3. Nutrition and lifestyle in mitObesity
    Session chairs: Alba Timon-Gomez and Adam Chicco

    15:30 – 15:55 Atan Gross: M(a)TCH2-ing up metabolism and apoptosis at the MOMbrane.
    15:55 – 16:20 Graham Holloway: Mitochondrial bioenergetics as a nexus-point for the beneficial effects of nitrate in diverse tissues.
    16:20 – 16:35 Patricia Owesny: Impairment of cardiac function and mitochondrial energy metabolism through diet induced obesity in aging.
    16:35 – 16:50 Pavla Stankova: Effect of telmisartan on nutritionally induced nonalcoholic steatohepatitis in mice.

    16:50 Coffee/tea break

    17:25 Session A4. Adipose tissue and fatty acid oxidation
    Session chairs: Luiza Cardoso and Pablo Garcia-Roves

    17:25 – 17:50 Petr Zouhar: Major site of non-shivering thermogenesis: brown fat or skeletal muscle?
    17:50 – 18:05 Lukas Alan: Dynamic complexomic analysis reveals a role for Von Willebrand Domain-containing Protein 8 (Vwa8) in mitochondrial morphology and substrate preference.
    18:05 – 18:20 Lisa Guerrier: Human white adipose tissue mitochondrial respiration: effect of body composition.
    18:20 – 18:45 Peter Schoenfeld: A view on brain's problem with fatty acid burning.

    19:00 Dinner

    20:30-21:30 Poster session

    Lukas Alan: Dynamic complexomic analysis reveals a role for Von Willebrand Domain-containing Protein 8 (Vwa8) in mitochondrial morphology and substrate preference.
    Daria Barkova: Effects of short term and long term aerobic-strength training on muscle metabolism in the elderly.
    Attila Kolonics: Accelerated epigenetic changes may contribute to the development of metabolic syndrome revealed by NADH FLIM.
    Murilo Othonicar: Mitochondrial alternative enzymes and supercomplexes: functional and evolutionary insights.
    Patricia Owesny: Impairment of cardiac function and mitochondrial energy metabolism through diet induced obesity in aging.
    Howard Phang: Screening marine natural products for bioenergetic effects in human cell models.
    Sarah Piel: Effect of dimethyl fumarate on cerebral mitochondrial metabolism in a porcine model of pediatric in-hospital cardiac arrest.
    Karolina Pytlak: Mitochondrial defect in human bronchial epithelial cells lacking the BKCa channel.
    Linsey Stiles: Mitochondrial Respirometry and ATP Hydrolysis Measurements in Previously Frozen Tissue Samples.

    2023-Jul-29 Saturday

    08:30 Session B1. Fatty acid oxidation
    Session chairs: Tal Yardeni and Anthony Molina

    08:30 – 08:55 Adam Chicco: Delta-6 desaturase inhibition reverses aberrant cardiolipin remodeling and mitochondrial dysfunction in the obese mouse heart.
    08:55 – 09:10 Cesare Granata: Novel mitochondrial respiration protocols reveal organ-specific reliance on ketone body metabolism in mice.
    09:10 – 09:25 Markus Keller: Exploring the influence of the lipid environment on mitochondrial membrane structure and function.
    09:25 – 09:40 Yvonne Wohlfarter: The Janus-faced nature of HSD10 in cardiolipin biosynthesis and mitochondrial function.
    09:40 – 09:55 Luke Whitcomb: Polyunsaturated fatty acid metabolism contributes to age-related impairment of cardiac mitochondrial calcium tolerance.
    09:55 – 10:10 Luiza Cardoso: Electron transfer from beta-oxidation and TCA cycle and impact of OXPHOS coupling on NADH and coenzyme Q redox states.

    10:10 Coffee/tea break

    10:30 Session B2. Type 2 Diabetes
    Session chairs: Sarah Piel and Markus Keller

    10:30 – 10:55 Christopher Axelrod: Skeletal muscle mitochondrial dynamics in obesity and type 2 diabetes.
    10:55 – 11:20 Pablo Garcia-Roves: Remission of obesity and insulin resistance. Is that enough?
    11:20 – 11:35 Pau Gama-Perez: Impact of obesity on white adipose tissue plasticity: addressing differential depot-specific responses.
    11:35 – 11:50 Dominik Pesta: Respiratory capacity of skeletal muscle and peripheral blood mononuclear cells of male and female individuals with type 2 diabetes.
    11:50 – 12:05 Lubos Sobotka: Macronutrients energy metabolism and obesity.

    12:05 - 15:30 Walk & Talk

    15:30 Session B3. Respiratory complexes
    Session chairs: Tatyana Court and Atan Gross

    15:30 – 15:55 Orian Shirihai: Inhibition of ATP synthase hydrolytic activity restores cellular energy homeostasis in conditions of impaired respiration.
    15:55 – 16:10 Maria Jose Saucedo-Rodriguez: Effect of succinate dehydrogenase deficiency on mitochondrial function.

    16:10 Coffee/tea break

    16:30 Session B4. Diagnostic approaches
    Session chairs: Alejandra Romero and Lubos Sobotka

    16:30 – 16:55 Alexander Karabatsiakis: Combined metabolite and lipid fingerprinting of blood serum reveals biomarker candidates of altered mitochondrial bioenergetics in peripheral blood mononuclear cells of female patients with depression.
    16:55 – 17:20 Dominique-Marie Votion: Serum acylcarnitines profile for diagnosis, prognosis and monitoring therapeutic intervention in equine atypical myopathy.
    17:20 – 17:35 Ksenija Vujacic-Mirski: Bioenergetics health index and parameters of mitochondrial respiration in relatively healthy individuals. Insight in mitochondrial respiration for diagnosis and future targeted treatments.
    17:35 – 17: 50 Alba Timon-Gomez: Substrate-uncoupler-inhibitor titration protocol for analyzing carbohydrate and fatty acid metabolism.

    17:50 – 18:00 Conclusions

    18:00 – 19:00 MiPs General Assembly

    19:00 Dinner

    20:30-21:30 Social evening. Award ceremony.

    2023-Jul-30 Sunday Departure
    09:00 Bus departure


    Oral presentations

     Title
    Votion 2023 MiP2023
    Votion Dominique-Marie
    Serum acylcarnitines profile for diagnosis, prognosis and monitoring therapeutic intervention in equine atypical myopathy.
    Alan 2023 MiP2023
    Alan Lukas
    Dynamic complexomic analysis reveals a role for Von Willebrand Domain-containing Protein 8 (Vwa8) in mitochondrial morphology and substrate preference.
    Karabatsiakis 2023 MiP2023
    Karabatsiakis Alexander
    Combined metabolite and lipid fingerprinting of blood serum reveals biomarker candidates of altered mitochondrial bioenergetics in peripheral blood mononuclear cells of female patients with depression.
    Gross 2023 MiP2023
    Gross Atan
    M(a)TCH2-ing up metabolism and apoptosis at the MOMbrane.
    Axelrod 2023 MiP2023
    Axelrod Christopher L
    Skeletal muscle mitochondrial dynamics in obesity and type 2 diabetes.
    Kayser 2023 MiP2023
    Kayser Bengt
    Obesity and hypoxia: from etiology to therapy.
    Brunetta 2023 MiP2023
    Brunetta Henver Simionato
    Chronic aerobic training reverts the negative effects of high-fat high-sucrose diet on the left ventricle of adipocyte-specific DICER knockout mice in association with improved mitochondrial function
    Cardoso 2023 MiP2023
    Cardoso Luiza HD
    Electron transfer from beta-oxidation and TCA cycle and impact of OXPHOS coupling on NADH and coenzyme Q redox states.
    Chicco 2023 MiP2023
    Chicco Adam J
    Delta-6 desaturase inhibition reverses aberrant cardiolipin remodeling and mitochondrial dysfunction in the obese mouse heart.
    Gnaiger 2023 MiP2023
    Erich Gnaiger
    From globesity to mitObesity.
    Gama Perez 2023 MiP2023
    Gama Perez Pau
    Impact of obesity on white adipose tissue plasticity: addressing depot-specific responses
    Garcia-Roves 2023 MiP2023
    Garcia-Roves Pablo Miguel
    Remission of obesity and insulin resistance. Is that enough?
    Holloway 2023 MiP2023
    Holloway Graham P
    Mitochondrial bioenergetics as a nexus-point for the beneficial effects of nitrate in diverse tissues.
    Granata 2023 MiP2023
    Granata Cesare
    Novel mitochondrial respiration protocols reveal organ-specific reliance on ketone body metabolism in mice.
    Guerrier 2023 MiP2023
    Guerrier Lisa
    Human white adipose tissue mitochondrial respiration: effect of body composition
    Hand 2023 MiP2023
    Hand Steven C
    Oxidative stress and repetitive metabolic transitions: Challenges due to lifestyle of invertebrate extremophiles.
    Keller 2023 MiP2023
    Keller Markus A
    Exploring the influence of the lipid environment on mitochondrial membrane structure and function.
    Vujacic-Mirski 2023 MiP2023
    Vujacic-Mirski Ksenija
    Bioenergetics health index and parameters of mitochondrial respiration in relatively healthy individuals. Insight in mitochondrial respiration for diagnosis and future targeted treatments.
    Larsen 2023 MiP2023
    Larsen Steen
    Mitochondrial adaptations to weight loss – lifestyle, surgery or medication.
    Sobotka 2023 MiP2023
    Sobotka Lubos
    Macronutrients energy metabolism and obesity.
    Mahapatra 2023 MiP2023
    Mahapatra Gargi
    Platelet bioenergetics reveals distinct systemic bioenergetic capacities associated with insulin sensitivity in older adults.
    Molina 2023 MiP2023
    Molina Anthony JA
    Targeting exercise intolerance in older, obese, heart failure patients.
    Owesny 2023 MiP2023
    Owesny Patricia
    Impairment of cardiac function and mitochondrial energy metabolism through diet induced obesity in aging.
    Pesta 2023 MiP2023
    Dominik Pesta
    Respiratory capacity of skeletal muscle and peripheral blood mononuclear cells of male and female individuals with type 2 diabetes.
    Petrick 2023 MiP2023
    Petrick Heather L
    Age- and sex-related differences in mitochondrial ADP sensitivity in human skeletal muscle.
    Sadler 2023 MiP2023
    Sadler Daniel
    Early life exercise training counters metabolic perturbations imparted by low parental cardiorespiratory fitness.
    Saucedo-Rodriguez 2023 MiP2023
    Saucedo Rodriguez Maria Jose
    Effect of succinate dehydrogenase deficiency on mitochondrial function.
    Schoenfeld 2023 MiP2023
    Schoenfeld Peter
    A view on brain's problem with fatty acid burning.
    Shirihai 2023 MiP2023
    Shirihai Orian
    Inhibition of ATP synthase hydrolytic activity restores cellular energy homeostasis in conditions of impaired respiration.
    Stankova 2023 MiP2023
    Stankova Pavla
    Effect of telmisartan on nutritionally induced nonalcoholic steatohepatitis in mice.
    Yardeni 2023 MiP2023
    Yardeni Tal
    The host immune system and the gut microbiota are regulated by the mitochondrial DNA.
    Timon-Gomez 2023 MiP2023
    Timon-Gomez Alba
    Substrate-uncoupler-inhibitor titration protocol for analyzing carbohydrate and fatty acid metabolism
    Whitcomb 2023 MiP2023
    Whitcomb Luke A
    Polyunsaturated fatty acid metabolism contributes to age-related impairment of cardiac mitochondrial calcium tolerance.
    Wohlfarter 2023 MiP2023
    Wohlfarter Yvonne
    The Janus-faced nature of HSD10 in cardiolipin biosynthesis and mitochondrial function.
    Zouhar 2023 MiP2023
    Zouhar Petr
    Major site of non-shivering thermogenesis: brown fat or skeletal muscle?
    Valencia 2023 MiP2023
    MiPsociety
    T-cell mitochondria exhibit a functional decline with obesity that is aggravated by weight loss.

    Poster presentations

     Title
    Kolonics 2023 MiP2023
    Kolonics Attila
    Accelerated epigenetic changes may contribute to the development of metabolic syndrome revealed by NADH FLIM.
    Piel 2023 MiP2023
    Piel Sarah
    Effect of dimethyl fumarate on cerebral mitochondrial metabolism in a porcine model of pediatric in-hospital cardiac arrest.
    Pytlak 2023 MiP2023
    MiPsociety
    Mitochondrial defect in human bronchial epithelial cells lacking the BKCa channel.
    Stiles 2023 MiP2023
    MiPsociety
    Mitochondrial respirometry and ATP hydrolysis measurements in previously frozen tissue samples
    Barkova 2023 MiP203
    MiPsociety
    Effects of short term and long term aerobic-strength training on muscle metabolism in the elderly.

    MiPsociety General Assembly 2023

    • The MiPsociety is an international organization, based in Austria and operating world-wide and has become a legal body in 2011 continuing a tradition of rigorous mitochondrial bioenergetics; integrating molecular, cellular and organismic physiology and pathology.
    Membership is open to all researchersMiPmembership
    Candidates for the election of the Executive MiPcommittee are listed here: MiPcommittee_2023 election candidates
    • The MiPs General Assembly will take place during the MiPconference 2023. All MiPmembers have a vote. All MiP223participants are invited to join.


    Social event

    The 'Trachtengruppe Umhausen' (translated: Folk group Umhausen) will perform traditional Tyrolean dance at its best.

    Trachtengruppe Umhausen 1.jpeg Trachtengruppe Umhausen 2.jpeg


    MIP announcement postcard 2023 digital-001.png
    MIP announcement postcard 2023.jpg

    Invited speakers


    Participants

    Last update 2023-07-17
    


    General information

    » and 20 years ago: MiP 2003


    Local organizers
    International committee


    Registration and abstract submission
    • Register for MiPconference only here or for both MiPevents here.
    • Abstracts accepted until event is fully booked.
    Submissions of original contributions on mitObesity and Healthy Aging for the MiP2023 conference are welcome.
    Format: Abstracts up to 250 words with DOI of collected abstracts, which may be extended to full BEC articles.
    » Guidelines and submission portal
    Travel info
    To guarantee a smooth transport from Innsbruck to Obergurgl, please arrange your arrival time in Innsbruck according to our travel info below.
    Student travel award
    What? Up to 350 EUR to cover travel costs to attend MiPschool or MiP2023.
    Who is eligible to apply? Undergrad and graduate students who have registered for either or both events.
    How? Apply by registering for a 2023 MiPevent, submitting an abstract and sending a short application letter to society@mitophysiology.org. Applications without registrations will not be considered.
    When? Registrations, abstracts and application letters must be received by July 9th. Students selected to receive the award will be notified by July 14th.


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