MiPNet27.05 Schroecken BEC tutorial-Living Communications pmP

From Bioblast

Bioenergetics Communications        
Tributes to pioneers in bioenergetics
Gnaiger 2020 BEC MitoPathways
Gnaiger Erich et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1.
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Publications in the MiPMap

Schroecken AT, 2022 Sep 30-Oct 03. BEC tutorial-Living Communications: pmF to pmP — pre IOC155.

Oroboros (2022-09-30) Mitochondr Physiol Network

Abstract: BEC tutorial-Living Communications. From Peter Mitchell’s protonmotive force to protonmotive pressure: elements of the science of bioenergetics. Preceding the Oroboros O2k-Workshop on high-resolution respirometry. Schroecken, Austria; 2022.

Gnaiger 2020 BEC MitoPathways

The mitochondrial membrane potential is an element of the science of bioenergetics, linked to the control of respiratory flux and related mitochondrial functions. A PubMed search on ‘mitochondrial membrane potential’ yields 40 000 results and 3452 for 2021 (search 2022-09-20), with a linear increase during the past 20 years. Chapter 8 on ‘Protonmotive pressure and respiratory control’ of Mitochondrial Pathways (Gnaiger 2020) introduces a novel perspective on Peter Mitchell’s protonmotive force, which incorporates the mitochondrial membrane potential. If you find the reading is tough, you are not alone. Join this BEC tutorial-Living Communications for a fundamental introduction into the relevant concepts of physical chemistry, which differ from misleading chapters in bioenergetics textbooks. A retreat with plenty of informal discussions and group interactions takes you on a journey to visit chemical potential differences versus potential gradients, Gibbs energy versus Gibbs force, quantities of capacity versus intensity, protonmotive force and motive units, flows and forces, and finally protonmotive pressure. This will introduce students (and teachers) to a new understanding of mitochondrial membrane potential and the protonmotive force, connecting the ideal gas equation, osmotic pressure, the Boltzmann constant and gas constant with Fick’s and Einstein’s diffusion equation. If theory gets dry and grey, join for a swim in lake Körbersee, for a Walk&Talk in the colorful alpine environment of the Schröcken-Tannberg region, and a visit to the Alpmuseum ufm Tannberg.

O2k-Network Lab: AT_Innsbruck_Oroboros

Figure 1.1. Coupling in oxidative phosphorylation is mediated by the protonmotive force pmF.
Last update: 2022-09-30

General information

Preceding the Oroboros O2k-Workshop on high-resolution respirometry, 2022 Oct 03-08 (Mo to Fr).


The event will be held in accordance with current COVID regulations. A primary concern must be the safety of our participants and staff, which is why we reserve the right to cancel the event if there are any concerns/restrictions. Refunds will be issued exclusively for registration fees.


Because of the current delays with several airlines, we would like to advise you to make sure to book flights that will allow you to arrive in Bregenz in time for the scheduled pickup. If you miss the scheduled transportation you will have to take a cab (Suggestion: Ritter Transport. Phone number: +43 664 34 11 540) or the public transportation to Schroecken. If you decide to take the public transportation, you will have to take the bus via Bregenz - Egg – Bezau – Schoppernau – Schröcken. You can book the ticket here: vmbol or here: oebb.
Please be aware that you will be responsible for paying for any additional transportation costs (about € 120 for a cab/ travel time 1 h; about € 11 for the public transportation).
Please check with your airline to see if there are any reimbursements available in the event that you miss the organized transport and have to arrange and pay for a cab or public transportation.


Schroecken Wiki.JPG
Hotel Körbersee, Schröcken, AT
Information on travel and venue: IOC Schroecken.


  • Understanding fundamental concepts and overcoming textbook errors: electrochemical potential and protonmotive force
  • Expand the theoretical foundation of science and point to future challenges: exergy, force, pressure — protonmotive force pmF to protonmotive pressure pmP
Sunrise on day 2 2022-10-01
  • Design experiments to test the pmP theorems
  • Improve interpretations - the meaning of measurements of mitochondrial membrane potential
  • Evaluate available methods to measure pmF and pmP
  • Design new protocols and instrumental tools to measure pmP
  • Think of applications: why pmF and pmP?
» Programme: BEC tutorial-Living Communications: pmF to pmP
  • Schroecken, 2022 Sep 30-Oct 03 (Fr to Mo)

Lecturer and participants


Impressions from the BEC tutorial-Living Communications pmP


Oroboros Instruments
High-Resolution Respirometry
Schoepfstrasse 18
A-6020 Innsbruck, Austria
Tel: +43 512 566796
Fax: +43 512 566796 20
Mitochondria and Cell Research

Hotel Koerbersee

» Please note that the hotel has a limited number of rooms and space is not guaranteed. Therefore, we ask you to confirm beforehand if you intend to bring accompanying guests with you.
» As there is no ATM close to the hotel, we recommend withdrawing money at Bregenz train station. Please make sure to bring some cash in EUROs with you, in case you need it.
The hotel accepts payment by credit card.


The event will be held in accordance with current COVID regulations. A primary concern must be the safety of our participants and staff, which is why we reserve the right to cancel the event if there are any concerns/restrictions. Refunds will be issued exclusively for registration fees.

Recommended reading

Hydrogen ion circuit and coupling in OXPHOS
Gnaiger 2020 BEC MitoPathways
  1. Mitchell P (1966) Chemiosmotic coupling in oxidative and photosynthetic phosphorylation. https://doi.org/10.1016/j.bbabio.2011.09.018
  2. Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. https://doi.org/10.26124/bec:2020-0002 - Chapter 8
  3. Gnaiger E (2021) The elementary unit — canonical reviewer's comments on: Bureau International des Poids et Mesures (2019) The International System of Units (SI) 9th ed. https://doi.org/10.26124/mitofit:200004.v2

» MitoPedia: Ergodynamics

BEC tutorials are listed as MitoGlobal Events.


ORO, IOC, 2022, MitoGlobal, NextGen-O2k 

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