Mito Xmas Meeting 2016 Innsbruck AT

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Innsbruck AT, 2016 Dec 16-17. Mito Xmas Meeting 2016. Mitochondrial function in health and disease. Mitochondr Physiol Network 21.03.

» Book of abstracts

Schrepfer E, Burtscher J (2016-12-16) MitoGlobal

Abstract: Mito Xmas Meeting 2016. Mitochondrial function in health and disease. Innsbruck, AT.


Bioblast editor: Burtscher J

Thank you

Dear participants of the Mito Xmas Conference!


Thank you so much for joining the meeting and making it such a great success! We hope, you enjoyed the presentations, discussions and social events as much as we did! We will soon make available the fotos online.
We really hope that we will meet again next year, maybe - as discussed - in Padova!
We wish you a great Christmas time and a happy New Year!!
Best wishes,
Emilie and Johannes


Organizers

Emilie Schrepfer (University of Padua) emilieschrepfer@yahoo.fr
Johannes Burtscher (Leopold-Franzens-University of Innsbruck, Medical University of Innsbruck) joh.burtscher@gmail.com, Johannes.Burtscher@i-med.ac.at



Programme

        • Programme Bioblast pdf
        • Book of abstracts with programme Bioblast pdf


        • Registration
  • Friday, Dec 16, 13.45-14.00
        • Invited Speakers
Day Time Speaker Title
Friday, Dec 16 14.15 Erich Gnaiger, AT The world as a laboratory: exploring mitochondrial fitness.
Friday, Dec 16 17.00 Elena Ziviani, IT To eat or not to eat: mitophagy in ageing and neurodegeneration.
Saturday, Dec 17 09.15 Pidder Jansen-Duerr, AT Mitochondria and aging.
Saturday, Dec 17 11.00 Marco Sandri, IT Mitochondrial quality control in muscle physiology and ageing.
Saturday, Dec 17 14.15 Mageni Soriano, IT Exploring the role of OPA1-MIC60 containing complexes in the regulation of cristae and cristae junctions biogenesis.
        • Host professors

Abstracts - Sessions

Session I (A1): Friday, Dec 16, 14:00

 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Gnaiger 2016 Abstract Mito Xmas Meeting InnsbruckA1
Oral
Review
The world as a laboratory: exploring mitochondrial fitness.Respiration
Comparative MiP;environmental MiP
Exercise physiology;nutrition;life style
HumanSkeletal muscle
Leanza 2016 Abstract Mito Xmas Meeting InnsbruckA1
Oral
Direct pharmacological targeting of a mitochondrial ion channel selectively kills melanoma cells in vivo.Pharmacology;toxicologyMouseCell death
Oxidative stress;RONS
Cancer
Omori 2016 Abstract Mito Xmas Meeting InnsbruckA1
Oral
Exploring the role of mitochondrial dynamics in melanocytes and melanomas.mt-Structure;fission;fusionCancer
Samardzic 2016 Abstract Mito Xmas Meeting InnsbruckA1
Oral
Increased Opa1 levels aggravate B cell lymphoma.mt-Structure;fission;fusionCell deathCancer

Session II (A2): Friday, Dec 16, 17:00

 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Oemer 2016b Abstract Mito Xmas Meeting InnsbruckA2
Oral
The impact of mitochondrial phospholipid remodeling on mitochondrial function.mt-Membrane
Patients
Human
Pig
Mouse
Zebrafish
Drosophila
Saccharomyces cerevisiae
Heart
Skeletal muscle
Liver
Kidney
Lung;gill
Fibroblast
Macrophage-derived
Oxidative stress;RONS
Mitochondrial disease
Inherited
Myopathy
Quintana-Cabrera 2016 Abstract Mito Xmas Meeting InnsbruckA2
Oral
Cyclophilin D stabilizes FOF1-ATPase dimers and cristae shape to modulate permeability transition pore.Ischemia-reperfusion
Permeability transition
Sumbalova 2016 Abstract Mito Xmas Meeting InnsbruckA2
Oral
Methods for evaluation of mitochondrial membrane potential with multi-sensor high-resolution respirometry: potentiometry vs fluorometry.Respiration
Instruments;methods
MouseNervous system
Ziviani 2016 Abstract Mito Xmas Meeting InnsbruckA2
Oral
Review
Playing hide and seek: inhibition of the Parkin-antagonizing deubiquitinase USP8 corrects a Drosophila PINK1 mutant model of Parkinson’s disease.mtDNA;mt-genetics
Pharmacology;toxicology
DrosophilaParkinson's


Session III (B1): Saturday, Dec 17, 09:15

 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Bean 2016 Abstract Mito Xmas Meeting InnsbruckB1
Oral
The mitochondria and cristae shaping protein Opa1 impinges on fat browning to control insulin sensitivity.mtDNA;mt-geneticsDiabetes
Cavinato 2016 Abstract Mito Xmas Meeting InnsbruckB1
Oral
Involvement of mitophagy in the elimination of damaged mitochondria during the process of UVB-induced senescence.HumanEndothelial;epithelial;mesothelial cell
Fibroblast
Oxidative stress;RONSAging;senescence
Fazzini 2016 Abstract Mito Xmas Meeting InnsbruckB1
Oral
Determination of mitochondrial copy number as versatile tool in epidemiology.mtDNA;mt-genetics
nDNA;cell genetics
Grespi 2016 Abstract Mito Xmas Meeting InnsbruckB1
Oral
MicroRNAs as modulators of mitochondrial remodeling and apoptosis.mt-Structure;fission;fusionCell death
Jansen-Duerr 2016 Abstract Mito Xmas Meeting InnsbruckB1
Oral
Mitochondria and aging.Aging;senescence
Khalid 2016 Abstract Mito Xmas Meeting InnsbruckB1
Oral
Prevention of mitochondrial oxidative damage: Novel insights into the activation of the pro-oxidant and pro-death function of p66Shc.mt-MedicineMouseHeart
Fibroblast
Cell death
Ischemia-reperfusion
Oxidative stress;RONS
Cardiovascular
Other
Sandri 2016 Abstract Mito Xmas Meeting InnsbruckB1
Oral
Review
Mitochondrial quality control in muscle physiology and ageing.Skeletal muscleAging;senescence

Session IV (B2): Saturday, Dec 17, 13:00

 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Doerrier 2016b Abstract Mito Xmas Meeting InnsbruckB2
Oral
Searching for specific targets of ischemic damage of cardiac mitochondria using O2k-Fluorometry.RespirationMouseHeartIschemia-reperfusion
Herkenne 2016 Abstract Mito Xmas Meeting InnsbruckB2
Oral
The mitochondrial shaping protein Optic Atrophy 1 (OPA1) controls angiogenesis.mt-Structure;fission;fusion
Scattolin 2016 Abstract Mito Xmas Meeting InnsbruckB2
Oral
Mitochondrial reactive oxygen species prime T-cell acute lymphoblastic leukemia to cell death by engaging the OMA1-OPA1 axis.mt-Structure;fission;fusionHumanBlood cells
Lymphocyte
Cell death
Oxidative stress;RONS
Cancer
Silic-Benussi 2016a Abstract Mito Xmas Meeting InnsbruckB2
Oral
mTORC inhibition increases ROS levels and induces cell death in T-ALL cells.Other
Soriano 2016 Abstract Mito Xmas Meeting InnsbruckB2
Oral
Exploring the role of OPA1-MIC60 containing complexes in the regulation of cristae and cristae junctions biogenesis.mt-Biogenesis;mt-density
Volani 2016 Abstract Mito Xmas Meeting InnsbruckB2
Oral
Effects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo.Respiration
Exercise physiology;nutrition;life style
mt-Medicine
MouseLiverOxidative stress;RONSOther


Posters

  • Fri, Dec 16, 15:30-17:00
  • Sat, Dec 17, 11:30-13:00
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Azzolini 2016 Abstract Mito Xmas Meeting InnsbruckPosterTargeting a mitochondrial potassium channel as a new way to treat chronic lymphocytic leukemia.Pharmacology;toxicologyHuman
Mouse
LymphocyteCell deathCancer
Barbieri 2016 Abstract Mito Xmas Meeting InnsbruckPosterAn alternatively spliced mitochondrial Fission 1 variant participates in mitochondrial elongation during autophagy.
Cerqueira 2016 Abstract Mito Xmas Meeting InnsbruckPosterThe Deubiquitinating (DUB) protein Ubiquitin carboxyl- terminal hydrolase L1 (UCH-L1) regulates Mitofusin-2 levels and  mitochondrial function in mammalian cell lines and in D. Melanogaster.Genetic knockout;overexpressionHexapodsParkinson's
Ciminale 2016 Abstract Mito Xmas Meeting InnsbruckPosterp13, a mitochondrial protein coded by human T-cell leukemia virus type 1.mt-MedicineHumanLymphocyteOxidative stress;RONSCancer
Infectious
Desbats 2016 Abstract Mito Xmas Meeting InnsbruckPosterCoQ biosynthetic proteins are physically and functionally related to respiratory supercomplexes in mammalian cells.Respiration
mtDNA;mt-genetics
Genetic knockout;overexpression
Patients
Human
Mouse
HEK
Fibroblast
Mitochondrial diseaseInherited
Myopathy
Neurodegenerative
Doerrier 2016a Abstract Mito Xmas Meeting InnsbruckPoster
MitoFit
K-Regio MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Respiration
Comparative MiP;environmental MiP
Gender
Exercise physiology;nutrition;life style
mt-Awareness
HumanSkeletal muscle
Blood cells
Aging;senescence
Espino 2016 Abstract Mito Xmas Meeting InnsbruckPosterMitochondrial [Ca2+] measurements using a novel very-low Ca2+ affinity aequorin-based probe.HumanHeLa
Garcia-Souza 2016 Abstract Mito Xmas Meeting InnsbruckPosterAssessment of fatty acid oxidation in mouse brain and liver mitochondria.Respiration
Exercise physiology;nutrition;life style
Nervous system
Liver
Krumschnabel 2016 Abstract Mito Xmas Meeting InnsbruckPosterEstablishment of a reference sample for high-resolution respirometry.Respiration
Instruments;methods
HumanHEKCryopreservation
Laner 2016 Abstract Mito Xmas Meeting InnsbruckPosterOXPHOS and ET capacity in permeabilized fibers of canine superathletes.Respiration
Comparative MiP;environmental MiP
Exercise physiology;nutrition;life style
DogSkeletal muscle
Lidron 2016 Abstract Mito Xmas Meeting InnsbruckPosterMCU knock-down impairs skeletal muscle and motor neuron development in zebrafish embryos.Genetic knockout;overexpression
Developmental biology
ZebrafishSkeletal muscle
Nervous system
Martorano 2016 Abstract Mito Xmas Meeting InnsbruckPosterOXPHOS complex impairment and mitochondrial DNA depletion modify hypoxia signaling pathway activity in zebrafish.RespirationZebrafishIschemia-reperfusion
Morbiato 2016 Abstract Mito Xmas Meeting InnsbruckPosterPurification of and characterization of human recombinant COQ4 and its putative Zn binding site mutants.
Neururer 2016 Abstract Mito Xmas Meeting InnsbruckPosterA project to develop a standardized minimum dataset to describe mitochondrial data.
Oemer 2016a Abstract Mito Xmas Meeting InnsbruckPosterMass spectrometric characterisation of cardiolipins reveals detailed insights into the structural diversity of mitochondrial phospholipids.
Penna 2016 Abstract Mito Xmas Meeting InnsbruckPosterImpact of CCDC90B on mitochondrial functions.
Peruzzo 2016 Abstract Mito Xmas Meeting InnsbruckPosterNovel psoralen-derivatives with increased solubility in cancer treatment.Cancer
Rigoni 2016 Abstract Mito Xmas Meeting InnsbruckPosterNucleoids and mtDNA dynamics regulation by mitochondrial ultrastructure.mtDNA;mt-genetics
Romanello 2016 Abstract Mito Xmas Meeting InnsbruckPosterContribution of mitochondrial dynamics to age-related muscle loss.mt-Structure;fission;fusion
Exercise physiology;nutrition;life style
Skeletal muscleAging;senescence
Schoepf 2016 Abstract Mito Xmas Meeting InnsbruckPosterMitochondrial function in primary prostate cancer.Patients
Respiration
mt-Medicine
mtDNA;mt-genetics
nDNA;cell genetics
HumanCancer
Serafini 2016 Abstract Mito Xmas Meeting InnsbruckPosterA novel role for the Parkinson’s disease gene LRRK2 as endoplasmic reticulum-mitochondria tether identified by a genome wide high content screen.MouseFibroblastParkinson's
Shibata 2016 Abstract Mito Xmas Meeting InnsbruckPosterLinear motor proteins induce mitochondrial shape change.mt-Structure;fission;fusion
Tsansizi 2016 Abstract Mito Xmas Meeting InnsbruckPosterPPM1K, novel insights in connecting metabolism and autophagy in the heart.
Weber 2016 Abstract Mito Xmas Meeting InnsbruckPosterLoss of PTEN in prostate cancer cells leads to a switch to succinate-mediated mitochondrial respiration associated with increased expression of NaDC3 and HIF-1alpha.Respiration
Genetic knockout;overexpression
Patients
Human
Mouse
GenitalCancer
Zanin 2016 Abstract Mito Xmas Meeting InnsbruckPosterLoss-of-function mutations in the SIGMAR1 gene cause distal hereditary motor neuropathy by impairing ER-mitochondria tethering and Ca2+ signaling.HumanEndothelial;epithelial;mesothelial cell
Neuroblastoma
Fibroblast
Inherited
Neurodegenerative

Mito Xmas Meeting 2016.jpg

Abstracts - alphabetical order

 PresentationSession
Azzolini 2016 Abstract Mito Xmas Meeting InnsbruckTargeting a mitochondrial potassium channel as a new way to treat chronic lymphocytic leukemia.Poster
Barbieri 2016 Abstract Mito Xmas Meeting InnsbruckAn alternatively spliced mitochondrial Fission 1 variant participates in mitochondrial elongation during autophagy.Poster
Bean 2016 Abstract Mito Xmas Meeting InnsbruckThe mitochondria and cristae shaping protein Opa1 impinges on fat browning to control insulin sensitivity.B1
Oral
Cavinato 2016 Abstract Mito Xmas Meeting InnsbruckInvolvement of mitophagy in the elimination of damaged mitochondria during the process of UVB-induced senescence.B1
Oral
Cerqueira 2016 Abstract Mito Xmas Meeting InnsbruckThe Deubiquitinating (DUB) protein Ubiquitin carboxyl- terminal hydrolase L1 (UCH-L1) regulates Mitofusin-2 levels and  mitochondrial function in mammalian cell lines and in D. Melanogaster.Poster
Ciminale 2016 Abstract Mito Xmas Meeting Innsbruckp13, a mitochondrial protein coded by human T-cell leukemia virus type 1.Poster
Desbats 2016 Abstract Mito Xmas Meeting InnsbruckCoQ biosynthetic proteins are physically and functionally related to respiratory supercomplexes in mammalian cells.Poster
Doerrier 2016a Abstract Mito Xmas Meeting Innsbruck
MitoFit
K-Regio MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Poster
Doerrier 2016b Abstract Mito Xmas Meeting InnsbruckSearching for specific targets of ischemic damage of cardiac mitochondria using O2k-Fluorometry.B2
Oral
Espino 2016 Abstract Mito Xmas Meeting InnsbruckMitochondrial [Ca2+] measurements using a novel very-low Ca2+ affinity aequorin-based probe.Poster
Fazzini 2016 Abstract Mito Xmas Meeting InnsbruckDetermination of mitochondrial copy number as versatile tool in epidemiology.B1
Oral
Garcia-Souza 2016 Abstract Mito Xmas Meeting InnsbruckAssessment of fatty acid oxidation in mouse brain and liver mitochondria.Poster
Gnaiger 2016 Abstract Mito Xmas Meeting InnsbruckThe world as a laboratory: exploring mitochondrial fitness.A1
Oral
Review
Grespi 2016 Abstract Mito Xmas Meeting InnsbruckMicroRNAs as modulators of mitochondrial remodeling and apoptosis.B1
Oral
Herkenne 2016 Abstract Mito Xmas Meeting InnsbruckThe mitochondrial shaping protein Optic Atrophy 1 (OPA1) controls angiogenesis.B2
Oral
Jansen-Duerr 2016 Abstract Mito Xmas Meeting InnsbruckMitochondria and aging.B1
Oral
Khalid 2016 Abstract Mito Xmas Meeting InnsbruckPrevention of mitochondrial oxidative damage: Novel insights into the activation of the pro-oxidant and pro-death function of p66Shc.B1
Oral
Krumschnabel 2016 Abstract Mito Xmas Meeting InnsbruckEstablishment of a reference sample for high-resolution respirometry.Poster
Laner 2016 Abstract Mito Xmas Meeting InnsbruckOXPHOS and ET capacity in permeabilized fibers of canine superathletes.Poster
Leanza 2016 Abstract Mito Xmas Meeting InnsbruckDirect pharmacological targeting of a mitochondrial ion channel selectively kills melanoma cells in vivo.A1
Oral
Lidron 2016 Abstract Mito Xmas Meeting InnsbruckMCU knock-down impairs skeletal muscle and motor neuron development in zebrafish embryos.Poster
Martorano 2016 Abstract Mito Xmas Meeting InnsbruckOXPHOS complex impairment and mitochondrial DNA depletion modify hypoxia signaling pathway activity in zebrafish.Poster
Morbiato 2016 Abstract Mito Xmas Meeting InnsbruckPurification of and characterization of human recombinant COQ4 and its putative Zn binding site mutants.Poster
Neururer 2016 Abstract Mito Xmas Meeting InnsbruckA project to develop a standardized minimum dataset to describe mitochondrial data.Poster
Oemer 2016a Abstract Mito Xmas Meeting InnsbruckMass spectrometric characterisation of cardiolipins reveals detailed insights into the structural diversity of mitochondrial phospholipids.Poster
Oemer 2016b Abstract Mito Xmas Meeting InnsbruckThe impact of mitochondrial phospholipid remodeling on mitochondrial function.A2
Oral
Omori 2016 Abstract Mito Xmas Meeting InnsbruckExploring the role of mitochondrial dynamics in melanocytes and melanomas.A1
Oral
Penna 2016 Abstract Mito Xmas Meeting InnsbruckImpact of CCDC90B on mitochondrial functions.Poster
Peruzzo 2016 Abstract Mito Xmas Meeting InnsbruckNovel psoralen-derivatives with increased solubility in cancer treatment.Poster
Quintana-Cabrera 2016 Abstract Mito Xmas Meeting InnsbruckCyclophilin D stabilizes FOF1-ATPase dimers and cristae shape to modulate permeability transition pore.A2
Oral
Rigoni 2016 Abstract Mito Xmas Meeting InnsbruckNucleoids and mtDNA dynamics regulation by mitochondrial ultrastructure.Poster
Romanello 2016 Abstract Mito Xmas Meeting InnsbruckContribution of mitochondrial dynamics to age-related muscle loss.Poster
Samardzic 2016 Abstract Mito Xmas Meeting InnsbruckIncreased Opa1 levels aggravate B cell lymphoma.A1
Oral
Sandri 2016 Abstract Mito Xmas Meeting InnsbruckMitochondrial quality control in muscle physiology and ageing.B1
Oral
Review
Scattolin 2016 Abstract Mito Xmas Meeting InnsbruckMitochondrial reactive oxygen species prime T-cell acute lymphoblastic leukemia to cell death by engaging the OMA1-OPA1 axis.B2
Oral
Schoepf 2016 Abstract Mito Xmas Meeting InnsbruckMitochondrial function in primary prostate cancer.Poster
Serafini 2016 Abstract Mito Xmas Meeting InnsbruckA novel role for the Parkinson’s disease gene LRRK2 as endoplasmic reticulum-mitochondria tether identified by a genome wide high content screen.Poster
Shibata 2016 Abstract Mito Xmas Meeting InnsbruckLinear motor proteins induce mitochondrial shape change.Poster
Silic-Benussi 2016a Abstract Mito Xmas Meeting InnsbruckmTORC inhibition increases ROS levels and induces cell death in T-ALL cells.B2
Oral
Soriano 2016 Abstract Mito Xmas Meeting InnsbruckExploring the role of OPA1-MIC60 containing complexes in the regulation of cristae and cristae junctions biogenesis.B2
Oral
Sumbalova 2016 Abstract Mito Xmas Meeting InnsbruckMethods for evaluation of mitochondrial membrane potential with multi-sensor high-resolution respirometry: potentiometry vs fluorometry.A2
Oral
Template 2016 Abstract Mito Xmas Meeting Innsbruck
Tsansizi 2016 Abstract Mito Xmas Meeting InnsbruckPPM1K, novel insights in connecting metabolism and autophagy in the heart.Poster
Volani 2016 Abstract Mito Xmas Meeting InnsbruckEffects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo.B2
Oral
Weber 2016 Abstract Mito Xmas Meeting InnsbruckLoss of PTEN in prostate cancer cells leads to a switch to succinate-mediated mitochondrial respiration associated with increased expression of NaDC3 and HIF-1alpha.Poster
Zanin 2016 Abstract Mito Xmas Meeting InnsbruckLoss-of-function mutations in the SIGMAR1 gene cause distal hereditary motor neuropathy by impairing ER-mitochondria tethering and Ca2+ signaling.Poster
Ziviani 2016 Abstract Mito Xmas Meeting InnsbruckPlaying hide and seek: inhibition of the Parkin-antagonizing deubiquitinase USP8 corrects a Drosophila PINK1 mutant model of Parkinson’s disease.A2
Oral
Review


Venue

Lecture Hall at the Department of Pharmacology, Peter-Mayr-Straße 1, 6020 Innsbruck, Austria


Accomodation

Pictures


Università degli Studi di Padova Leopold-Franzens-Universität Innsbruck tirol - Unser Land Medizinische Universität Innsbruck link=http://wiki.oroboros.at/index.php/OROBOROS_INSTRUMENTS OROBOROS MitoFit


FONDAZIONE RICERCA BIOMEDICA AVANZATA - ISTITUTO VENETO DI MEDICINA MOLECOLARE - VIMM SPIN SFB f44 Universität Innsbruck Italien-Zentrum


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