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Jaramillo-Jimenez 2023 Mitochondrion | Jaramillo-Jimenez A, Giil LM, Borda MG, Tovar-Rios DA, Kristiansen KA, Bruheim P, Aarsland D, Barreto GE, Berge RK (2023) Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: network analysis and cognitive prognosis. Mitochondrion 71:17-25. https://doi.org/10.1016/j.mito.2023.05.002 | 2023 | PMID: 37172667 |
Hosler 2023 Mitochondrion | Hosler J, Hoang N, Shirey Edwards K (2023) The cyclic lipopeptide micafungin induces rupture of isolated mitochondria by reprograming the mitochondrial inner membrane anion channel. Mitochondrion 71:50-62. https://doi.org/10.1016/j.mito.2023.05.004 | 2023 | [https://www.ncbi.nlm.nih.gov/pubmed/37201620 PMID: 37201620 Open Access |
Bahire 2023 Mitochondrion | Bahire KL, Maļuhins R, Bello F, Freitag SV, Jeļisejevs I, Gile R, Upīte J, Plesnila N, Jansone B (2023) Hemispheric analysis of mitochondrial complex I and II activity in the mouse model of ischemia-reperfusion-induced injury. https://doi.org/10.1016/j.mito.2023.02.005 | 2023 | Mitochondrion 69:147-158. PMID: 36764500 |
Munro 2022 Mitochondrion | Munro D, Rodríguez E, Blier PU (2022) The longest-lived metazoan, Arctica islandica, exhibits high mitochondrial H2O2 removal capacities. https://doi.org/10.1016/j.mito.2022.11.005 | 2022 | Mitochondrion 68:81-86. PMID: 36427759 Open Access |
Mendes 2022 Mitochondrion | Mendes D, Peixoto F, Oliveira MM, Andrade PB, Videira RA (2022) Mitochondria research and neurodegenerative diseases: On the track to understanding the biological world of high complexity. https://doi.org/10.1016/j.mito.2022.05.001 | 2022 | Mitochondrion 65:67-79. PMID: 35623557 Open Access |
Bandara 2021 Mitochondrion | Bandara AB, Drake JC, James CC, Smyth JW, Brown DA (2021) Complex I protein NDUFS2 is vital for growth, ROS generation, membrane integrity, apoptosis, and mitochondrial energetics. Mitochondrion 58:160-68. | 2021 | PMID: 33744462 Open Access |
Holody 2021 Mitochondrion | Holody C, Anfray A, Mast H, Lessard M, Han WH, Carpenter R, Bourque S, Sauvé Y, Lemieux H (2021) Differences in relative capacities of oxidative phosphorylation pathways may explain sex- and tissue-specific susceptibility to vision defects due to mitochondrial dysfunction. Mitochondrion 56:102-10. | 2021 | PMID: 33271347 Open Access |
Silaidos 2020 Mitochondrion | Silaidos C, Grube J, Muley C, Eckert GP (2020) Time-dependent melatonin secretion is associated with mitochondrial function in peripheral blood mononuclear cells (PBMC) of male volunteers. Mitochondrion 53:21-29. | 2020 | PMID: 32304866 |
Duong 2020 Mitochondrion | Duong QV, Hoffman A, Zhong K, Dessinger MJ, Zhang Y, Bazil JN (2020) Calcium overload decreases net free radical emission in cardiac mitochondria. Mitochondrion 51:126-39. | 2020 | PMID: 31982614 |
Venediktova 2020 Mitochondrion | Venediktova NI, Mashchenko OV, Talanov EY, Belosludtseva NV, Mironova GD (2020) Energy metabolism and oxidative status of rat liver mitochondria in conditions of experimentally induced hyperthyroidism. Mitochondrion 52:190-96. | 2020 | PMID: 32278087 |
Ranganathan 2020 Mitochondrion | Ranganathan A, Owiredu S, Jang DH, Eckmann DM (2020) Prophylaxis of mitochondrial dysfunction caused by cellular decompression from hyperbaric exposure . Mitochondrion 52:8-19. | 2020 | PMID: 32045716 |
Knight 2020 Mitochondrion | Knight KM, Shelkowitz E, Larson AA, Mirsky DM, Wang Y, Chen T, Wong LJ, Friederich MW, Van Hove JLK (2020) The mitochondrial DNA variant m.9032T > C in MT-ATP6 encoding p.(Leu169Pro) causes a complex mitochondrial neurological syndrome. Mitochondrion 55:8-13. | 2020 | PMID: 32931937 |
Gumpp 2020 Mitochondrion | Gumpp AM, Behnke A, Bach AM, Piller S, Boeck C, Rojas R, Kolassa IT (2020) Mitochondrial bioenergetics in leukocytes and oxidative stress in blood serum of mild to moderately depressed women. Mitochondrion 58:14-23. | 2020 | PMID: 33383159 |
Cecatto 2020 Mitochondrion | Cecatto C, Amaral AU, Wajner A, Wajner SM, Castilho RF, Wajner M (2020) Disturbance of mitochondrial functions associated with permeability transition pore opening induced by cis-5-tetradecenoic and myristic acids in liver of adolescent rats. Mitochondrion 50:1-13. | 2020 | PMID: 31655165 Open Access |
Krylova 2019 Mitochondrion | Krylova TD, Sheremet NL, Tabakov VY, Lyamzaev KG, Itkis YS, Tsygankova PG, Andreeva NA, Shmelkova MS, Nevinitsyna TA, Kadyshev VV, Zakharova EY (2019) Three rare pathogenic mtDNA substitutions in LHON patients with low heteroplasmy. Mitochondrion 50:139-144. | 2019 | PMID: 31669237 Open Access |
Bettink 2019 Mitochondrion | Bettink MAW, Harms FA, Dollee N, Specht PAC, Raat NJH, Schoonderwoerd GC, Mik EG (2019) Non-invasive versus ex vivo measurement of mitochondrial function in an endotoxemia model in rat: toward monitoring of mitochondrial therapy. Mitochondrion 50:149-57. | 2019 | PMID: 31770610 Open Access |
Ramkumar 2019 Mitochondrion | Ramkumar B, Dharaskar SP, Mounika G, Paithankar K, Sreedhar AS (2019) Mitochondrial chaperone, TRAP1 as a potential pharmacological target to combat cancer metabolism. Mitochondrion 50:42-50. | 2019 | PMID: 31669620 Open Access |
Havird 2019 Mitochondrion | Havird JC, Noe GR, Link L, Torres A, Logan DC, Sloan DB, Chicco AJ (2019) Do angiosperms with highly divergent mitochondrial genomes have altered mitochondrial function? Mitochondrion 49:1-11. | 2019 | PMID: 31229574 |
Lauridsen 2019 Mitochondrion | Lauridsen PE, Rasmussen LJ, Desler C (2019) Mitochondrial oxidative phosphorylation capacity of cryopreserved cells. Mitochondrion 47:47-53. | 2019 | PMID: 31051261 |
Itkis 2019 Mitochondrion | Itkis Y, Krylova T, Pechatnikova NL, De Grassi A, Tabakov VY, Pierri CL, Aleshin V, Boyko A, Bunik VI, Zakharova EY (2019) A novel variant m.641A>T in the mitochondrial MT-TF gene is associated with epileptic encephalopathy in adolescent. Mitochondrion 47:10-17. | 2019 | PMID: 31009750 |
Govindaraj 2019 Mitochondrion | Govindaraj P, Rani B, Sundaravadivel P, Vanniarajan A, Indumathi KP, Khan NA, Dhandapany PS, Rani DS, Tamang R, Bahl A, Narasimhan C, Rakshak D, Rathinavel A, Premkumar K, Khullar M, Thangaraj K (2019) Mitochondrial genome variations in idiopathic dilated cardiomyopathy. Mitochondrion 48:51-59. | 2019 | PMID: 30910572 |
De Moura Alvorcem 2018 Mitochondrion | De Moura Alvorcem L, Britto R, Parmeggiani B, Glanzel NM, Da Rosa-Junior NT, Cecatto C, Bobermin LD, Amaral AU, Wajner M, Leipnitz G (2018) Evidence that thiol group modification and reactive oxygen species are involved in hydrogen sulfide-induced mitochondrial permeability transition pore opening in rat cerebellum. Mitochondrion 47:141-50. | 2018 | PMID: 30399433 |
Chakrabarty 2018 Mitochondrion | Chakrabarty S, Kabekkodu SP, Singh RP, Thangaraj K, Singh KK, Satyamoorthy K (2018) Mitochondria in health and disease. Mitochondrion 43:25-29. | 2018 | PMID: 29944924 |
Sokolov 2018 Mitochondrion | Sokolov EP, Sokolova IM (2018) Compatible osmolytes modulate mitochondrial function in a marine osmoconformer Crassostrea gigas (Thunberg, 1793). Mitochondrion 45:29-37. | 2018 | PMID: 29458112 |
Palmfeldt 2017 Mitochondrion | Palmfeldt J, Bross P (2017) Proteomics of human mitochondria. Mitochondrion 33:2-14. | 2017 | |
Zand 2017 Mitochondrion | Zand K, Pham TDA, Li J, Zhou W, Wallace DC, Burke PJ (2017) Resistive flow sensing of vital mitochondria with nanoelectrodes. Mitochondrion 37:8-16. | 2017 | PMID: 28655663 |
Jang 2017 Mitochondrion | Jang DH, Greenwood JC, Owiredu S, Ranganathan A, Eckmann DM (2017) Mitochondrial networking in human blood cells with application in acute care illnesses. Mitochondrion 44:27-34. | 2017 | PMID: 29275149 |
Karlsson 2016 Mitochondrion | Karlsson M, Ehinger JK, Piel S, Sjövall F, Henriksnäs J, Höglund U, Hansson MJ, Elmér E (2016) Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – an in vivo large animal model. Mitochondrion 31:56-62. | 2016 | PMID: 27769952 |
Doerrier 2016 Mitochondrion | Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63. | 2016 | PMID: 26748191 |
Lemieux 2016 Mitochondrion | Lemieux H, Boemer F, van Galen G, Serteyn D, Amory H, Baise E, Cassart D, van Loon G, Marcillaud-Pitel C, Votion DM (2016) Mitochondrial function is altered in horse atypical myopathy. Mitochondrion 30:35-41. | 2016 | PMID: 27374763 |
Boeck 2016 Mitochondrion | Boeck C, Koenig AM, Schury K, Geiger ML, Karabatsiakis A, Wilker S, Waller C, Gündel H, Fegert JM, Calzia E, Kolassa IT (2016) Inflammation in adult women with a history of child maltreatment: The involvement of mitochondrial alterations and oxidative stress. Mitochondrion 30:197-207. | 2016 | PMID: 27530300 |
Kilbaugh 2016 Mitochondrion | Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS (2016) Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury. Mitochondrion 26:19-25. | 2016 | PMID: 26549476 Open Access |
Houben 2015 Mitochondrion | Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Determination of muscle mitochondrial respiratory capacity in Standardbred racehorses as an aid to predicting exertional rhabdomyolysis. Mitochondrion 24:99-104. | 2015 | PMID: 26219220 |
Ziak 2015 Mitochondrion | Ziak J, Krajcova A, Jiroutkova K, Nemcova V, Dzupa V, Duska F (2015) Assessing the function of mitochondria in cytosolic context in human skeletal muscle: Adopting high-resolution respirometry to homogenate of needle biopsy tissue samples. Mitochondrion 21:106-12. | 2015 | PMID: 25701243 |
Burtscher 2015 Mitochondrion | Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12. | 2015 | PMID: 26516105 Open Access |
D'Erchia 2014 Mitochondrion | D'Erchia AM, Atlante S, Gadaleta G, Pavesi G, Chiara M, De Virgilio C, Manzari C, Mastropasqua F, Prazzoli GM, Picardi E, Gissi C, Horner D, Reyes A, Sbisa E, Tullo A, Pesole G (2014) Tissue-specific mtDNA abundance from exome data and its correlation 2 with mitochondrial transcription, mass and respiratory activity. Mitochondrion 970:1-9. | 2014 | PMID: 25446395 |
Van Bergen 2014 Mitochondrion | Van Bergen NJ, Blake RE, Crowston JG, Trounce IA (2014) Oxidative phosphorylation measurement in cell lines and tissues. Mitochondrion 15:24-33. | 2014 | PMID: 24657935 |
Trumbeckaite 2013 Mitochondrion | Trumbeckaite S, Gizatullina Z, Arandarcikaite O, Röhnert P, Vielhaber S, Malesevic M, Fischer G, Seppet E, Striggow F, Gellerich FN (2013) Oxygen glucose deprivation causes mitochondrial dysfunction in cultivated rat hippocampal slices: Protective effects of CsA, its immunosuppressive congener [D-Ser](8)CsA, the novel non-immunosuppressive cyclosporin derivative Cs9, and the NMDA receptor antagonist MK 801. Mitochondrion 13:539–47. | 2013 | PMID: 22824458 |
Hroudova 2013 Mitochondrion | Hroudová J, Fišar Z, Kitzlerová E, Zvěřová M, Raboch J (2013) Mitochondrial respiration in blood platelets of depressive patients. Mitochondrion 13:795-800. | 2013 | PMID: 23688905 |
Sjoevall 2013 Mitochondrion | Sjövall F, Ehinger JK, Marelsson SE, Morota S, Asander Frostner E, Uchino H, Lundgren J, Arnbjörnsson E, Hansson Magnus J, Fellman V, Elmér E (2013) Mitochondrial respiration in human viable platelets - methodology and influence of gender, age and storage. Mitochondrion 13:7-14. | 2013 | PMID: 23164798 Open Access |
Ceusters 2013 Mitochondrion | Ceusters Justine D, Mouithys-Mickalad AA, Franck TJ, Derochette S, Vanderplasschen A, Deby-Dupont GP, Serteyn DA (2013) Effect of myeloperoxidase and anoxia/reoxygenation on mitochondrial respiratory function of cultured primary equine skeletal myoblasts. Mitochondrion 13:410-16. | 2013 | PMID:23268199 |
Brown 2012 Mitochondrion | Brown GC, Borutaite V (2012) There is no evidence that mitochondria are the main source of reactive oxygen species in mammalian cells. Mitochondrion 12:1-4. | 2012 | PMID:21303703 Open Access |
Aguirre 2012 Mitochondrion | Aguirre E, Lopez-Bernardo E, Cadenas S (2012) Functional evidence for nitric oxide production by skeletal-muscle mitochondria from lipopolysaccharide-treated mice. Mitochondrion 12:126-31. | 2012 | PMID: 21664300 |
Ziegler 2012 Mitochondrion | Ziegler CG, Peng M, Falk MJ, Polyak E, Tsika E, Ischiropoulos H, Bakalar D, Blendy JA, Gasser DL (2012) Parkinson's disease-like neuromuscular defects occur in prenyl diphosphate synthase subunit 2 (Pdss2) mutant mice. Mitochondrion 12:248-57. | 2012 | PMID: 21983691 Open Access |
Pierron 2012 Mitochondrion | Pierron D, Letellier T, Grossman LI (2012) Mitogroup: continent-specific clusters of mitochondrial OXPHOS complexes based on nuclear non-synonymous polymorphisms. Mitochondrion 12: 237-241. | 2012 | PMID: 21968253 |
Correa 2012 Mitochondrion | Correa CC, Aw WC, Melvin RG, Pichaud N, Ballard JWO (2012) Mitochondrial DNA variants influence mitochondrial bioenergetics in Drosophila melanogaster. Mitochondrion 12:459-64. | 2012 | PMID: 22735574 |
Govindaraj 2011 Mitochondrion | Govindaraj P, Khan NA, Gopalakrishna P, Chandra RV, Vanniarajan A, Reddy AA, Singh S, Kumaresan R, Srinivas G, Singh L, Thangaraj K (2011) Mitochondrial dysfunction and genetic heterogeneity in chronic periodontitis. Mitochondrion 11:504-12. | 2011 | PMID: 21296687 |
Comelli 2011 Mitochondrion | Comelli M, Domenis R, Bisetto E, Contin M, Marchini M, Ortolani F, Tomasetig L, Mavelli I (2011) Cardiac differentiation promotes mitochondria development and ameliorates oxidative capacity in H9c2 cardiomyoblasts. Mitochondrion 11:315-26. | 2011 | PMID: 202010 |
Gizatullina 2011 Mitochondrion | Gizatullina ZZ, Gaynutdinov TM, Svoboda H, Jerzembek D, Knabe A, Vielhaber S, Malesevic M, Heinze HJ, Fischer G, Striggow F, Gellerich FN (2011) Effects of cyclosporine A and its immunosuppressive or non-immunosuppressive derivatives [D-Ser]8-CsA and Cs9 on mitochondria from different brain regions. Mitochondrion 11(3):421-9. | 2011 | PMID: 21167961 |
Thomas 2011 Mitochondrion | Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr (2011) Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18. | 2011 | PMID: 20727424 Open Access |
Kelly 2011 Mitochondrion | Kelly OM, McNamara YM, Manzke LH, Meegan MJ, Porter RK (2011) The preservation of in vivo phosphorylated and activated uncoupling protein 3 (UCP3) in isolated skeletal muscle mitochondria following administration of 3,4-methylenedioxymethamphetamine (MDMA aka ecstasy) to rats/mice. Mitochondrion. 12:110-19. | 2011 | PMID:21453795 |
Djafarzadeh 2011 Mitochondrion | Djafarzadeh S, Vuda M, Takala J, Ochs M, Jakob SM (2011) Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. Mitochondrion 11:83-8. | 2011 | PMID: 20691286 |
Boushel 2011 Mitochondrion | Boushel RC, Gnaiger E, Calbet JA, Gonzalez-Alonso J, Wright-Paradis C, Sondergaard H, Ara I, Helge JW, Saltin B (2011) Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans. Mitochondrion 11:303-7. | 2011 | PMID: 21147270 |
Pecinova 2011 Mitochondrion | Pecinova A, Drahota Z, Nuskova H, Pecina P, Houstek J (2011) Evaluation of basic mitochondrial functions using rat tissue homogenates. Mitochondrion 11:722-8. | 2011 | PMID:21664301 Open Access |
Mendelev 2011 Mitochondrion | Mendelev N, Mehta SL, Witherspoon S, He Q, Sexton JZ, Li PA (2011) Upregulation of human selenoprotein H in murine hippocampal neuronal cells promotes mitochondrial biogenesis and functional performance. Mitochondrion 11:76-82. | 2011 | PMID: 20656065 Open Access |
Montaigne 2011 Mitochondrion | Montaigne D, Marechal X, Preau S, Baccouch R, Modine T, Fayad G, Lancel S, Neviere R (2011) Doxorubicin induces mitochondrial permeability transition and contractile dysfunction in the human myocardium. Mitochondrion 11:22-6. | 2011 | PMID:20599629 |
Tranah 2011 Mitochondrion | Tranah GJ, Manini TM, Lohman KK, Nalls MA, Kritchevsky S, Newman AB, Harris TB, Miljkovic I, Biffi A, Cummings SR, Liu Y (2011) Mitochondrial DNA variation in human metabolic rate and energy expenditure. Mitochondrion 11:855-61. | 2011 | PMID: 21586348 Open Access |
Roy Chowdhury 2011 Mitochondrion | Roy Chowdhury SK, Dobrowsky RT, Fernyhough P (2011) Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes. Mitochondrion 11:845-54. | 2011 | PMID: 21742060 Open Access |
Guillet 2010 Mitochondrion | Guillet V, Chevrollier A, Cassereau J, Letournel F, Gueguen N, Richard L, Desquiret V, Verny C, Procaccio V, Amati-Bonneau P, Reynier P, Bonneau D (2010) Ethambutol-induced optic neuropathy linked to OPA1 mutation and mitochondrial toxicity. Mitochondrion 10:115-24. | 2010 | PMID: 19900585 |
Caro 2010 Mitochondrion | Caro P, Gómez J, Arduini A, González-Sánchez M, González-García M, Borrás C, Viña J, Puertas MJ, Sastre J, Barja G (2010) Mitochondrial DNA sequences are present inside nuclear DNA in rat tissues and increase with age. Mitochondrion 10:479-86. | 2010 | PMID: 20546951 |
Kotarsky 2010 Mitochondrion | Kotarsky H, Karikoski R, Mörgelin M, Marjavaara S, Bergman P, Zhang DL, Smet J, van Coster R, Fellman V (2010) Characterization of complex III deficiency and liver dysfunction in GRACILE syndrome caused by a BCS1L mutation. Mitochondrion 10:497-509. | 2010 | PMID: 20580947 |
Iyer 2009 Mitochondrion | Iyer S, Thomas R, Portell F, Dunham L, Quigley C, Bennett JP (2009) Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression. Mitochondrion 9:196-203. | 2009 | PMID: 19460293 Open Access |
Miles 2007 Mitochondrion | Miles MV (2007) The uptake and distribution of coenzyme Q(10). Mitochondrion 7 Suppl:S72-7. | 2007 | PMID:17446143 |
Tran 2007 Mitochondrion | Tran UC, Clarke CF (2007) Endogenous synthesis of coenzyme Q in eukaryotes. Mitochondrion 7 Suppl:S62-71. | 2007 | PMID:17482885 Open Access |
Mayevsky 2007 Mitochondrion | Mayevsky A, Chance B (2007) Oxidation–reduction states of NADH in vivo: From animals to clinical use. Mitochondrion 7:330-9. | 2007 | PMID: 17576101 |
Bentinger 2007 Mitochondrion | Bentinger M, Brismar K, Dallner G (2007) The antioxidant role of coenzyme Q. Mitochondrion Suppl:S41-50. | 2007 | PMID:17482888 |
Hassoun 2006 Mitochondrion | Hassoun SM, Lancel S, Petillot P, Decoster B, Favory R, Marchetti P, Neviere R (2006) Sphingosine impairs mitochondrial function by opening permeability transition pore. Mitochondrion 6:149-54. | 2006 | PMID: 16725383 |
Gellerich 2004 Mitochondrion | Gellerich FN, Mayr JA, Reuter S, Sperl W, Zierz S (2004) The problem of interlab variation in methods for mitochondrial disease diagnosis: enzymatic measurement of respiratory chain complexes. Mitochondrion 4:427-39. | 2004 | PMID: 16120404 |
Puchowicz 2004 Mitochondrion | Puchowicz MA, Varnes ME, Cohen BH, Friedman NR, Kerr DS, Hoppel CL (2004) Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria-case studies. Mitochondrion 4:377-85. | 2004 | PMID: 16120399 |
Brewer 2004 Mitochondrion | Brewer GJ, Jones TT, Wallimann T, Schlattner U (2004) Higher respiratory rates and improved creatine stimulation in brain mitochondria isolated with anti-oxidants. Mitochondrion 4:49-57. | 2004 | PMID: 16120374 |
Vishnevsky 2003 Mitochondrion | Vishnevsky EL, Kondrashova MN, Pushkar DY, Vishnevsky E, Demidov AA, Sirota TV, Temnov AV, Khunderyakova NV, Zakharchenko MV, Kosyakova NI (2003) Role of the impairment of oxidative metabolism in pathogenesis of lower urinary tract symptoms with benign prostatic hyperplasia and their treatment by alpha1-adrenoblocker alfuzosin. Mitochondrion 3: 67-73. | 2003 | PMID: 16120345 |