Molina 2022 Abstract Bioblast

From Bioblast
Jump to navigation Jump to search

Bioblast2022 banner.jpg

3.2. «10+5»
Molina Anthony JA
Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina Anthony JA (2022) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older women. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint«

Link: Bioblast 2022: BEC Inaugural Conference

Heimler Stephanie R, Phang Howard J, Bergstrom Jaclyn, Mahapatra Gargi, Dozier Stephen, Gnaiger Erich, Molina Anthony JA (2022)

Event: Bioblast 2022

This study investigates relationships between platelet mitochondrial bioenergetics and resting metabolic rate (RMR), body composition, and exercise fitness in women over 60 years of age. We report positive correlations between peak respiratory exchange ratio (RER) and RMR with five measures of platelet respiration, supporting the premise that blood cells can be utilized to report on mitochondrial function associated with physical health and fitness. Identifying mechanisms associated with physical performance among older adults supports the development of reliable biomarkers of healthy aging and can advance the development of efficacious interventions.

Keywords: platelets, resting metabolic rate RMR, cardiopulmonary exercise testing, OXPHOS capacity P, electron transfer capacity E, inverted regression analysis

O2k-Network Lab: AT Innsbruck Oroboros, US CA San Diego Molina AJA, US NC Winston-Salem Molina AJA


Affiliations

Heimler SR1, Phang HJ1, Bergstrom J1, Mahapatra G2, Dozier S1, Gnaiger E3, Molina AJA1
  1. Division of Geriatrics, Gerontology, and Palliative Care; Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA - ajmolina@health.ucsd.edu
  2. Section on Gerontology and Geriatrics, Sticht Center for Healthy Aging and Alzheimer's Prevention, Department of Internal Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA
  3. Oroboros Instruments, Innsbruck, Austria

Figures

Graphical abstract

List of abbreviations, terms and definitions - MitoPedia

» MitoPedia: Terms and abbreviations


Labels: MiParea: Respiration, Exercise physiology;nutrition;life style 


Organism: Human  Tissue;cell: Blood cells  Preparation: Permeabilized cells 


Coupling state: OXPHOS, ET  Pathway: F, N, S, Gp, ROX  HRR: Oxygraph-2k  Event: A3