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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
Moore Anthony L
MitoPedia topics: EAGLE
COST: Member COST WG1: WG1 COST WG2: WG2 COST WG3: WG3 COST WG4: WG4
Name | Moore Anthony L, Prof. PhD |
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Institution | Biochemistry and Medicine,
School of Life Sciences, University of Sussex, UK |
Address | Falmer, BN1 9QG |
City | Brighton |
State/Province | |
Country | United Kingdom |
a.l.moore@sussex.ac.uk | |
Weblink | http://www.sussex.ac.uk/lifesci/moorelab/ |
O2k-Network Lab | UK Brighton Moore AL |
Labels:
Field of research: Basic, Clinical, Pharmacological
Publications
Published | Reference | |
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Balmaceda 2024 Biochim Biophys Acta Mol Basis Dis | 2024 | Balmaceda V, Komlodi T, Szibor M, Gnaiger E, Moore AL, Fernandez-Vizarra E, Viscomi C (2024) The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease. Biochim Biophys Acta Mol Basis Dis 1870:167033. https://doi.org/10.1016/j.bbadis.2024.167033 |
Komlodi 2021 BEC Q | 2021 | KomlΓ³di T, Cardoso LHD, Doerrier C, Moore AL, Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. Bioenerg Commun 2021.3. https://doi.org/10.26124/bec:2021-0003 |
Copsey 2021 Sci Rep | 2021 | Copsey AC, Barsottini MRO, May B, Xu F, Albury MS, Young L, Moore AL (2021) Kinetic characterisation and inhibitor sensitivity of Candida albicans and Candida auris recombinant AOX expressed in a self-assembled proteoliposome system. Sci Rep 11:14748. |
BEC 2020.1 doi10.26124bec2020-0001.v1 | 2020 | Gnaiger E et al β MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 |
Barsottini 2020 Commun Biol | 2020 | Barsottini MRO, Copsey A, Young L, Baroni RM, Cordeiro AT, Pereira GAG, Moore AL (2020) Biochemical characterization and inhibition of the alternative oxidase enzyme from the fungal phytopathogen Moniliophthora perniciosa. Commun Biol 3:263. |
Szibor 2019 Biochim Biophys Acta Bioenerg | 2019 | Szibor Marten, Gainutdinov Timur, Fernandez-Vizarra Erika, Dufour Eric, Gizatullina Zemfira, Debska-Vielhaber Grazyna, Heidler Juliana, Wittig Ilka, Viscomi Carlo, Gellerich Frank Norbert, Moore Anthony L (2019) Bioenergetic consequences from xenotopic expression of a tunicate AOX in mouse mitochondria: switch from RET and ROS to FET. Biochim Biophys Acta Bioenerg 1861:148137. |
Young 2013 Biochem Soc Trans | 2013 | Young L, Shiba T, Harada S, Kita K, Albury MS, Moore AL (2013) The alternative oxidases: simple oxidoreductase proteins with complex functions. Biochem Soc Trans 41:1305-11. |
Young 2013 Biochim Soc Trans | 2013 | Young L, Shiba T, Harada S, Kita K, Albury MS, Moore AL (2013) The alternative oxidases: simple oxidoreductase proteins with complex functions. Biochem Soc Trans 41:1305-11. |
Albury 2009 Physiol Plant | 2009 | Albury MS, Elliott C, Moore AL (2009) Towards a structural elucidation of the alternative oxidase in plants. Physiol Plant 137:316-27. |
Affourtit 2001 J Biol Chem | 2001 | Affourtit C, Krab K, Leach GR, Whitehouse DG, Moore AL (2001) New insights into the regulation of plant succinate dehydrogenase. On the role of the protonmotive force. J Biol Chem 276:32567-74. |
Affourtit 1999 J Biol Chem | 1999 | Affourtit C, Albury MS, Krab K, Moore AL (1999) Functional expression of the plant alternative oxidase affects growth of the yeast Schizosaccharomyces pombe. J Biol Chem 274:6212-8. |
Wagner 1998 Plant Physiol | 1998 | Wagner AM, Wagner MJ, Moore AL (1998) In vivo ubiquinone reduction levels during thermogenesis in araceae. Plant Physiol 117:1501-6. |
Affourtit 1998 J Biol Chem | 1998 | Affourtit C, Albury MS, Krab K, Moore AL (1998) Functional expression of the plant alternative oxidase affects growth of the yeast Schizosaccharomyces pombe. J Biol Chem 274:6212-8. |
Van den Bergen 1994 Eur J Biochem | 1994 | Van den Bergen CW, Wagner AM, Krab K, Moore AL (1994) The relationship between electron flux and the redox poise of the quinone pool in plant mitochondria. Interplay between quinol-oxidizing and quinone-reducing pathways. Eur J Biochem 226:1071-8. |
Day 1991 Plant Physiol | 1991 | Day DA, Dry IB, Soole KL, Wiskich JT, Moore AL (1991) Regulation of alternative pathway activity in plant mitochondria: deviations from Q-pool behavior during oxidation of NADH and quinols. Plant Physiol 95:948-53. |
Moore 1991 Plant Physiol | 1991 | Moore AL, Dry IB, Wiskich JT (1991) Regulation of electron transport in plant mitochondria under state 4 conditions. Plant Physiol 95:34-40. |
Zannoni 1990 FEBS Lett | 1990 | Zannoni D, Moore AL (1990) Measurement of the redox state of the ubiquinone pool in Rhodobacter capsulatus membrane fragments. FEBS Lett 271:123-7. |
Dry 1989 Arch Biochem Biophys | 1989 | Dry IB, Moore AL, Day DA, Wiskich JT (1989) Regulation of alternative pathway activity in plant mitochondria: nonlinear relationship between electron flux and the redox poise of the quinone pool. Arch Biochem Biophys 273:148-57. |
Moore 1988 FEBS Letters | 1988 | Moore AL, Dry IB, Wiskich TJ (1988) Measurement of the redox state of the ubiquinone pool in plant mitochondria. FEBS Lett 235:76-80. |
Cottingham 1983 Biochim Biophys Acta | 1983 | Cottingham IR, Moore AL (1983) Ubiquinone pool behaviour in plant mitochondria. Biochim Biophys Acta 724:191-200. |
Abstracts
Published | Reference | |
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Komlodi 2022 Q10 Hamburg | 2022 | Komlodi T, Cardoso LHD, Doerrier C, Moore AL, Rich PR, Gnaiger E (2022) The mitochondrial Q-junction and coenzyme Q pools: Continuous monitoring of pull and push control of respiration and redox state of the Q-mimetic CoQ2. Q10 Hamburg. |
Ravasz 2019 Abstract IOC141 | 2019 | Ravasz D, Bui D, Kitayev A, Greenwood B, Hill C, Komlodi T, Doerrier C, Ozohanics O, Moore AL, Gnaiger E, Kiebish M, Kolev K, Seyfried TN, Willis WT, Narain N, Adam-Vizi V, Chinopoulos C (2019) Endogenous quinones sustain a moderate NADH oxidation by Complex I during anoxia. Mitochondr Physiol Network 24.02. |
Komlodi 2018 EBEC2018 | 2018 | Electron supply to the Q-junction: assessment of mitochondrial respiration, H2O2 flux and the redox state of the Q-pool. |
Komlodi 2018b EBEC2018 | 2018 | Endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria. |
Ravasz 2018 Abstract The evolving concept of mitochondria | 2018 | Vast pools of endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria. |
Komlodi 2018 AussieMit | 2018 | Komlodi T, Hunger M, Moore AL, Gnaiger E (2018) Electron transfer at the Q-junction: new perspectives from combined measurement of mitochondrial O2 flux, H2O2 flux, and coenzyme Q redox state. AussieMit 2018 Melbourne AU. |
Moore 2017 MiPschool Obergurgl | 2017 | The electron transfer-pathway β Q redox regulation and mitochondrial pathways to oxygen. |
Moore 2017 MiPschool Obergurgl E1 | 2017 | Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives. |
Moore 2016 Abstract IOC116 | 2016 | Moore AL (2016) Investigations into the multi-faceted roles of the alternative oxidases: are they a reflection of the nature of the hydrophobic cavity? Mitochondr Physiol Network 21.11 |
NextGen-O2k
- Prof. Anthony L Moore is Key Opinion Leader (KOL) in the NextGen-O2k project.