Nedergaard J

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Working Groups

Short-Term Scientific Missions

Management Committee

Members

COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Nedergaard J

MitoPedia topics: EAGLE

COST: Member COST WG1: WG1

COST WG3: WG3

COST Mentor: Mentor

WG3 Leader - Management Committee MitoEAGLE

Name	Nedergaard Jan, Dr.
Institution	Department of Metabolic Research The Arrhenius Laboratories F3 Stockholm University
Address	, S-106 91
City	Stockholm
State/Province
Country	Sweden
Email	jan.nedergaard@su.se
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O2k-Network Lab	SE Stockholm Nedergaard J

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Publications

	Published	Reference
Shabalina 2024 Biochim Biophys Acta Bioenerg	2024	Shabalina IG, Jiménez B, Sousa-Filho CPB, Cannon B, Nedergaard J (2024) In isolated brown adipose tissue mitochondria UCP1 is not essential for nor involved in the uncoupling effects of the classical uncouplers FCCP and DNP. Biochim Biophys Acta Bioenerg [Epub ahead of print]. https://doi.org/10.1016/j.bbabio.2024.149516
Gao 2022 Biochim Biophys Acta Bioenerg	2022	Gao Y, Shabalina IG, Braz GRF, Cannon B, Yang G, Nedergaard J (2022) Establishing the potency of N-acyl amino acids versus conventional fatty acids as thermogenic uncouplers in cells and mitochondria from different tissues.
Nabben 2011 Biochim Biophys Acta	2011	Nabben M, Shabalina IG, Moonen-Kornips E, van Beurden D, Cannon B, Schrauwen P, Nedergaard J, Hoeks J (2011) Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice. Biochim Biophys Acta 1807:1095-105.
Cannon 2008 Methods Mol Biol	2008	Cannon B, Nedergaard J (2008) Studies of thermogenesis and mitochondrial function in adipose tissues. Methods Mol Biol 456:109-21.

Abstracts

	Published	Reference
Gao 2019 MiPschool Coimbra	2019	Effects on mitochondrial respiration of N-acyl amino acids versus common fatty acids.
Shabalina 2018 MiP2018	2018	Elovl2-ablation leads to mitochondrial phospholipid remodeling and reduced oxidative phosphorylation capacity in mouse liver mitochondria.
Shabalina 2017 Abstract MITOEAGLE Barcelona	2017	Control of UCP1 activity in brown fat mitochondria.
Shabalina 2017 MiP2017	2017	In UCP1-ablated mice, prolonged cold exposure promotes mitochondrial dysfunction, apoptosis and inflammation in brown adipose tissue, and accumulation of visceral obesogenic fat.
Nedergaard 2017 MiP2017	2017	Creatine effect in mitochondria from different tissues.
Kalinovich 2015 Abstract MiP2015	2015	UCP3-related changes in brown and brite/beige adipose tissue in cold-acclimated mice.
Shabalina 2015 Abstract MiP2015	2015	The metabolically inert environmental pollutants perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria.
Mahdaviani 2014 Abstract MiP2014	2014	Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure.
Shabalina 2013 Abstract IOC79	2013	Shabalina IG (2013) Enhanced Complex I but low Complex II substrate-derived ROS production rates in mice, prematurely aging due to enhanced mitochondrial DNA mutation rate. Mitochondr Physiol Network 18.07
Shabalina 2013 Abstract MiP2013	2013	Shabalina IG, Petrovic N, Kalinovich AV, Cannon B, Nedergaard J (2013) Comparative study of brown and white adipose tissue mitochondria in mice upon cold acclimation. Mitochondr Physiol Network 18.08.

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