Nolfi-Donegan 2020 Redox Biol

From Bioblast
Publications in the MiPMap
Nolfi-Donegan D, Braganza A, Shiva S (2020) Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement. Redox Biol 37:101674.

Β» PMID: 32811789 Open Access

Nolfi-Donegan D, Braganza A, Shiva S (2020) Redox Biol

Abstract: The mitochondrial electron transport chain utilizes a series of electron transfer reactions to generate cellular ATP through oxidative phosphorylation. A consequence of electron transfer is the generation of reactive oxygen species (ROS), which contributes to both homeostatic signaling as well as oxidative stress during pathology. In this graphical review we provide an overview of oxidative phosphorylation and its inter-relationship with ROS production by the electron transport chain. We also outline traditional and novel translational methodology for assessing mitochondrial energetics in health and disease.

β€’ Bioblast editor: Gnaiger E

Nolfi-Donegan 2020 Redox Biol CORRECTION.png

Correction: FADH2 and Complex II

Ambiguity alert.png
FADH2 is shown as the substrate feeding electrons into Complex II (CII). This is wrong and requires correction - for details see Gnaiger (2024).
Gnaiger E (2024) Complex II ambiguities ― FADH2 in the electron transfer system. J Biol Chem 300:105470. - Β»Bioblast linkΒ«

Labels: MiParea: Respiration 

Coupling state: LEAK, ROUTINE, ET 

HRR: Oxygraph-2k 

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