O2k-Publications: DQ

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O2k-Publications: DQ

O2k-Publications: Topics
Electron transfer-pathway states
» MitoPedia: DQ-pathway control state


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Default sorting: chronological. Empty fields appear first in ascending order. 
 YearReferenceCouplingPathwayPreparationOrganismTissue;cell
Teh 2019 Mol Cancer Ther2019Teh JT, Zhu WL, Newgard CB, Casey PJ, Wang M (2019) Respiratory capacity and reserve predict cell sensitivity to mitochondria inhibitors: mechanism-based markers to identify metformin-responsive cancers. Mol Cancer Ther 18:693-705.LEAK
ROUTINE
OXPHOS
ET
N
S
DQ
ROX
Intact cells
Permeabilized cells
Permeabilized tissue
Human
Mouse
Other cell lines
Paech 2018b Toxicology2018Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23.LEAK
OXPHOS
ET
N
S
DQ
CIV
ROX
NS
Isolated mitochondriaMouseLiver
Hsiao 2018 Anal Biochem2018Hsiao CP, Hoppel C (2018) Analyzing mitochondrial function in human peripheral blood mononuclear cells. Anal Biochem 549:12-20.OXPHOS
ET
F
N
S
DQ
CIV
NS
ROX
Intact cellsHumanBlood cells
Chen 2018 Hum Mol Genet2018Chen A, Tiosano D, Guran T, Baris HN, Bayram Y, Mory A, Shapiro-Kulnane L, Hodges CA, Coban Akdemir Z, Turan S, Jhangiani SN, van den Akker F, Hoppel CL, Salz HK, Lupski JR, Buchner DA (2018) Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency. Hum Mol Genet 27:1913-26.OXPHOS
ET
F
N
S
DQ
CIV
NS
Isolated mitochondriaHumanEndothelial;epithelial;mesothelial cell
Fibroblast
Ravasz 2018 Biochim Biophys Acta2018Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2018) Reduction of 2-methoxy-1,4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD+ supports substrate-level phosphorylation during respiratory inhibition. Biochim Biophys Acta 1859:909-24.LEAK
OXPHOS
DQ
F
N
Isolated mitochondriaMouseLiver
Barca 2018 Hum Mol Genet2018Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12.LEAK
ROUTINE
OXPHOS
ET
F
N
S
DQ
NS
ROX
Intact cells
Permeabilized cells
HumanFibroblast
Paech 2018a Toxicology2018Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44.ET
LEAK
OXPHOS
CIV
DQ
N
ROX
S
Isolated mitochondria
Permeabilized cells
Human
Mouse
Liver
Other cell lines
Paech 2017 Arch Toxicol2017Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M (2017) Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072. Arch Toxicol 91:3647-62.LEAK
OXPHOS
ET
N
S
DQ
CIV
ROX
Permeabilized cellsHumanLiver
Other cell lines
Luethi 2017 Toxicology2017Luethi D, Liechti ME, Krähenbühl S (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology 387:57-66.OXPHOS
ET
NS
N
S
DQ
CIV
ROX
Permeabilized cellsHumanLiver
Mathers 2017 J Comp Physiol B2017Mathers KE, McFarlane SV, Zhao L, Staples JF (2017) Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes. J Comp Physiol B 187:227-34.LEAK
OXPHOS
N
S
CIV
ROX
DQ
Intact cells
Isolated mitochondria
Other mammalsLiver
Haegler 2017 PLOS ONE2017Haegler P, Grünig D, Berger B, Terracciano L, Krähenbühl S, Bouitbir J (2017) Hepatic effects of pharmacological doses of hydroxy-cobalamin[c-lactam] in mice. PLOS ONE 12:e0171026.LEAK
OXPHOS
ET
N
S
CIV
ROX
DQ
HomogenateMouseLiver
Brecht 2016 Toxicol In Vitro2016Brecht K, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, Krähenbühl S, Uteng M (2016) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicol In Vitro 40:55-65.LEAK
OXPHOS
ET
N
S
CIV
Other combinations
ROX
DQ
Permeabilized cellsHumanIslet cell;pancreas;thymus
Teh 2015 Oncogene2015Teh JT, Zhu WL, Ilkayeva OR, Li Y, Gooding J, Casey PJ, Summers SA, Newgard CB, Wang M (2015) Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. Oncogene 34:3296-304.OXPHOSN
S
DQ
CIV
ROX
Permeabilized cellsHumanOther cell lines
Ye 2013 Anal Biochem2013Ye F, Hoppel CL (2013) Measuring oxidative phosphorylation in human skin fibroblasts. Anal Biochem 437:52-8.OXPHOSN
S
DQ
CIV
Permeabilized cellsHumanSkeletal muscle
Fibroblast
O2k-Publications: Topics

O2k-Publications: Pathway control state DQ - Abstracts

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