O2k-Publications: Inhibitor

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O2k-Publications: Inhibitor

O2k-Publications in the MiPMap

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 YearReferenceOrganismTissue;cell
Malagrino 2019 Oxid Med Cell Longev2019Malagrinò F, Zuhra K, Mascolo L, Mastronicola D, Vicente JB, Forte E, Giuffrè A (2019) Hydrogen sulfide oxidation: adaptive changes in mitochondria of SW480 colorectal cancer cells upon exposure to hypoxia. Oxid Med Cell Longev 2019:8102936.HumanEndothelial;epithelial;mesothelial cell
Lemieux 2019 bioRxiv2019Lemieux H, Subarsky P, Doblander C, Wurm M, Troppmair J, Gnaiger E (2019) Mitochondrial respiratory function as an early biomarker of apoptosis induced by growth factor removal. bioRxiv doi: https://doi.org/10.1101/151480 .MouseBlood cells
Niu 2018 Cancer Metab2018Niu X, Chen YJ, Crawford PA, Patti GJ (2018) Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells. Cancer Metab 6:19.HumanHeLa
Lu 2018 ACS Infect Dis2018Lu X, Williams Z, Hards K, Tang J, Cheung CY, Aung HL, Wang B, Liu Z, Hu X, Lenaerts AJ, Woolhiser L, Hastings C, Zhang X, Wang Z, Rhee KY, Ding K, Zhang T, Cook GM (2018) A pyrazolo[1,5-a]pyridine inhibitor of the respiratory cytochrome bcc complex for the treatment of drug-resistant tuberculosis. ACS Infect Dis 5:239-49.Eubacteria
Boutoual 2018 Scientific Reports2018Boutoual, R., Meseguer, S., Villarroya, M., Martin-Hernandez, E., Errami, M., Martin, M. A., Casado, M., and Armengod, M. E. (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARgamma-UCP2-AMPK axis. Scientific reports 8, 1163HumanOther cell lines
Fibroblast
Treberg 2018 Comp Biochem Physiol B Biochem Mol Biol2018Treberg JR, Braun K, Zacharias P, Kroeker K (2018) Multidimensional mitochondrial energetics: Application to the study of electron leak and hydrogen peroxide metabolism. Comp Biochem Physiol B Biochem Mol Biol 224:121-28.Mouse
Rat
Skeletal muscle
Belosludtsev 2018 Biochemistry (Mosc)2018Belosludtsev KN, Belosludtseva NV, Tenkov KS, Sharapov VA, Kosareva EA, Dubinin MV (2018) Effect of dequalinium on respiration and the inner membrane permeability of rat liver mitochondria. Biochemistry (Mosc) 12:121–27.RatLiver
Sant'Anna-Silva 2018 Front Oncol2018Sant'Anna-Silva ACB, Santos GC, Campos SPC, Oliveira Gomes AM, Pérez-Valencia JA, Rumjanek FD (2018) Metabolic profile of oral squamous carcinoma cell lines relies on a higher demand of lipid metabolism in metastatic cells. Front Oncol 8:13.HumanOther cell lines
Fibroblast
Rekuviene 2018 Thesis2018Rekuvienė E (2018) Effect of respiratory complex I inhibitors on mitochondrial permeability transition and cell viability during brain ischemia. Doctoral Dissertation 138.RatNervous system
Treberg 2018 Redox Biol2018Treberg JR, Braun K, Selseleh P (2018) Mitochondria can act as energy-sensing regulators of hydrogen peroxide availability. Redox Biol 20:483-88.RatSkeletal muscle
Havird 2018 bioRxiv2018Havird JC, Noe GR, Link L, Torres A, Logan DC, Sloan DB, Chicco AJ (2018) Assessing mitochondrial function in angiosperms with highly divergent mitochondrial genomes. bioRxiv doi: https://doi.org/10.1101/448902.Plants
Zholobenko 2017 PLOS ONE2017Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691.RatHeart
Jezek 2017 Biochim Biophys Acta2017Ježek J, Engstová H, Ježek P (2017) Antioxidant mechanism of mitochondria-targeted plastoquinone SkQ1 is suppressed in aglycemic HepG2 cells dependent on oxidative phosphorylation. Biochim Biophys Acta 1858:750-62.HumanLiver
Rodrigues-Silva 2017 J Neurooncol2017Rodrigues-Silva E, Siqueira-Santos ES, Ruas JS, Ignarro RS, Figueira TR, Rogério F, Castilho RF (2017) Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity. J Neurooncol 133:519-29.RatNervous system
Davis 2017 Tissue Eng Part C Methods2017Davis BN, Santoso JW, Walker MJ, Cheng CS, Koves TR, Kraus WE, Truskey GA (2017) Human, tissue-engineered, skeletal muscle myobundles to measure oxygen uptake and assess mitochondrial toxicity. Tissue Eng Part C Methods 23:189-99.HumanSkeletal muscle
Cockova 2017 Thesis2017Čočková Z (2017) Modulation of RNA demethylase FTO function in SH-SY5Y cells: the effect on insulin signaling and mitochondrial respiration. Diploma Thesis p70.HumanNervous system
Luethi 2017 Toxicology2017Luethi D, Liechti ME, Krähenbühl S (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology 387:57-66.HumanLiver
Krishnathas 2017 Med Chem Comm2017Krishnathas R, Bonke E, Dröse S, Zickermann V, Nasiri HR (2017) Identification of 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine as a novel, highly potent and specific inhibitor of mitochondrial complex I. Med Chem Comm 8:657-61.RatHeart
Rekuviene 2017 Data Brief2017Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Data on effects of rotenone on calcium retention capacity, respiration and activities of respiratory chain complexes I and II in isolated rat brain mitochondria. Data Brief 13:707-12.RatNervous system
Lemieux 2017 Sci Rep2017Lemieux H, Blier PU, Gnaiger E (2017) Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in permeabilized fibers. Sci Rep 7:2840, DOI:10.1038/s41598-017-02789-8.MouseHeart
Stepanova 2017 J Cereb Blood Flow Metab2017Stepanova A, Kahl A, Konrad C, Ten V, Starkov AS, Galkin A (2017) Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia reperfusion injury. J Cereb Blood Flow Metab 37:3649-58.MouseNervous system
Fisar 2017 Indian J Biochem Biophys2017Fišar Z, Hroudová J, Namrata S, Macečková D, Kopřivová A (2017) Protocols for high-resolution respirometry experiments to test the activity of electron transfer system of pig brain mitochondria. Indian J Biochem Biophys 54:258-72.PigNervous system
Sidlauskas 2017 Neurosci Lett2017Sidlauskas K, Sidlauskiene R, Li N, Liobikas J (2017) 5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. Neurosci Lett 639:207-14.RatNervous system
Other cell lines
Hu 2017 Proc Natl Acad Sci U S A2017Hu H, Nan J, Sun Y, Zhu D, Xiao C, Wang Y, Zhu L, Wu Y, Zhao J, Wu R, Chen J, Yu H, Hu X, Zhu W, Wang J (2017) Electron leak from NDUFA13 within mitochondrial complex I attenuates ischemia-reperfusion injury via dimerized STAT3. Proc Natl Acad Sci U S A 114:11908-13.Mouse
Rekuviene 2017 Neurosci Lett2017Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Rotenone decreases ischemia-induced injury by inhibiting mitochondrial permeability transition in mature brains. Neurosci Lett 653:45-50.RatNervous system
Bueno 2016 Thesis2016Bueno e Silva MM (2016) Alterações mitocondriais e reprogramação metabólica em células de glioblastoma após tratamento com temozolomida. Dissertation p71.HumanNervous system
Other cell lines
Valenzuela 2016 Cell Death Dis2016Valenzuela R, Costa-Besada MA, Iglesias-Gonzalez J, Perez-Costas E, Villar-Cheda B, Garrido-Gil P, Melendez-Ferro M, Soto-Otero R, Lanciego JL, Henrion D, Franco R, Labandeira-Garcia JL (2016) Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration. Cell Death Dis 7:e2427.Mouse
Rat
Nervous system
Amaral 2016 Biochim Biophys Acta2016Amaral AU, Cecatto C, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Wajner M (2016) cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca2+ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency. Biochim Biophys Acta 1857:1363-72.RatNervous system
Liver
Nemeth 2016 FASEB J2016Németh B, Doczi J, Csete D, Kacso G, Ravasz D, Adams D, Kiss G, Nagy AM, Horvath G, Tretter L, Mócsai A, Csépányi-Kömi R, Iordanov I, Adam-Vizi V, Chinopoulos C (2016) Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. FASEB J 30:286-300.MouseLiver
Bastian 2016 Cancer Lett2016Bastian A, Matsuzaki S, Humphries KM, Pharaoh GA, Doshi A, Zaware N, Gangjee A, Ihnat MA (2016) AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization. Cancer Lett pii: S0304-3835(16)30745-5.Mouse
Stepanova 2016 Biochim Biophys Acta2016Stepanova A, Shurubor Y, Valsecchi F, Manfredi G, Galkin A (2016) Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart. Biochim Biophys Acta 1857:1561-8.MouseHeart
Nervous system
Hawley 2016 Diabetes2016Hawley SA, Ford RJ, Smith BK, Gowans GJ, Mancini SJ, Pitt RD, Day EA, Salt IP, Steinberg GR, Hardie DG (2016) The Na+/glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels. Diabetes 65:2784-94.Human
Mouse
Liver
HEK
Amaral 2016 J Neurochem2016Amaral AU, Cecatto C, Castilho RF, Wajner M (2016) 2-methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria. J Neurochem 137:62-75.RatNervous system
Miotto 2016 Biochem J2016Miotto PM, Holloway GP (2016) In the absence of phosphate shuttling, exercise reveals the in vivo importance of creatine-independent mitochondrial ADP transport. Biochem J 473:2831-43.MouseSkeletal muscle
Ruas 2016 PLOS ONE2016Ruas JS, Siqueira-Santos ES, Amigo I, Rodrigues-Silva E, Kowaltowski AJ, Castilho RF (2016) Underestimation of the maximal capacity of the mitochondrial electron transport system in oligomycin-treated cells. PLOS ONE 11:e0150967.Human
Rat
Nervous system
Genital
Other cell lines
Villani 2016 Mol Metab2016Villani LA, Smith BK, Marcinko K, Ford RJ, Broadfield LA, Green AE, Houde VP, Muti P, Tsakiridis T, Steinberg GR (2016) The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration. Mol Metab 5:1048-56.HumanGenital
Munro 2016 Free Radic Biol Med2016Munro D, Banh S, Sotiri E, Tamanna N, Treberg JR (2016) The thioredoxin and glutathione-dependent H2O2 consumption pathways in muscle mitochondria: Involvement in H2O2 metabolism and consequence to H2O2 efflux assays. Free Radic Biol Med 96:334-46.RatSkeletal muscle
Warne 2015 J Biol Chem2015Warne J, Pryce G, Hill J, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AW, Towers GJ, Coker A, Duchen MR, Szabadkai G, Baker D, Selwood D (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73.MouseLiver
Grefte 2015 Biochim Biophys Acta2015Grefte S, Wagenaars JA, Jansen R, Willems PH, Koopman WJ (2015) Rotenone inhibits primary murine myotube formation via Raf-1 and ROCK2. Biochim Biophys Acta 1853:1606-14.MouseSkeletal muscle
Other cell lines
Makrecka-Kuka 2015 Biomolecules2015
O2k-Protocols contents
Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. Biomolecules 5:1319-38.
Human
Mouse
Heart
Nervous system
HEK
Varikmaa 2014 Biochim Biophys Acta2014Varikmaa M, Bagur R, Kaambre T, Grichine A, Timohhina N, Tepp K, Shevchuk I, Chekulayev V, Metsis M, Boucher F, Saks V, Kuznetsov AV, Guzun R (2014) Role of mitochondria-cytoskeleton interactions in respiration regulation and mitochondrial organization in striated muscles. Biochim Biophys Acta 1837:232-45.RatHeart
Skeletal muscle
Kaldma 2014 Int J Biochem Cell Biol2014Kaldma A, Klepinin A, Chekulayev V, Mado K, Shevchuk I, Timohhina N, Tepp K, Kandashvili M, Varikmaa M, Koit A, Planken M, Heck K, Truu L, Planken A, Valvere V, Rebane E, Kaambre T (2014) An in situ study of bioenergetic properties of human colorectal cancer: The regulation of mitochondrial respiration and distribution of flux control among the components of ATP synthasome. Int J Biochem Cell Biol 55C:171-86.HumanGenital
Pecina 2014 Biochim Biophys Acta Clinical2014Pecina P, Houstkova H, Mracek T, Pecinova A, Nuskova H.Tesarova M, Hansikova H, Janota J, Zemanc J, Houstek J (2014) Noninvasive diagnostics of mitochondrial disorders in isolated lymphocytes with high resolution respirometry. Biochim Biophys Acta Clinical 2:62–71.HumanBlood cells
Lymphocyte
Klepinin 2014 J Bioenerg Biomembr2014Klepinin A, Chekulayev V, Timohhina N, Shevchuk I, Tepp K, Kaldma A, Koit A, Saks V, Kaambre T (2014) Comparative analysis of some aspects of mitochondrial metabolism in differentiated and undifferentiated neuroblastoma cells. J Bioenerg Biomembr 46:17-31.MouseHeart
Other cell lines
Kaambre 2013 Front Physiol2013Kaambre T, Chekulayev V, Shevchuk I, Tepp K, Timohhina N, Varikmaa M, Bagur R, Klepinin A, Anmann T, Koit A, Kaldma A, Guzun R, Valvere V, Saks V (2013) Metabolic control analysis of respiration in human cancer tissue. Front Physiol 4:151.HumanEndothelial;epithelial;mesothelial cell
Vielhaber 2013 Acta Neuropathol2013Vielhaber S, Debska-Vielhaber G, Peeva V, Schoeler S, Kudin AP, Minin I, Schreiber S, Dengler R, Kollewe K, Zuschratter W, Kornblum C, Zsurka G, Kunz WS (2013) Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion. Acta Neuropathol 125:245-56.HumanSkeletal muscle
Hall 2013 Biochim Biophys Acta2013Hall A, Larsen AK, Parhamifar L, Meyle KD, Wu LP, Moghimi SM (2013) High-resolution respirometry analysis of polyethylenimine-mediated mitochondrial energy crisis and cellular stress: Mitochondrial proton leak and inhibition of the electron transport system. Biochim Biophys Acta 1827:1213-25.MouseLiver
Other cell lines
Costa 2013 Cell Death Dis2013Costa AC, Loh SH, Martins LM (2013) Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease. Cell Death Dis 4:e467.Drosophila
Felser 2013 Toxicol Sci2013Felser A, Blum K, Lindinger PW, Bouitbir J, Kraehenbuehl S (2013) Mechanisms of hepatocellular toxicity associated with dronedarone - a comparison to amiodarone. Toxicol Sci 131:480-90.Human
Rat
Liver
Jardim-Messeder 2012 Int J Biochem Cell Biol2012Jardim-Messeder D, Camacho-Pereira J, Galina A (2012) 3-Bromopyruvate inhibits calcium uptake by sarcoplasmic reticulum vesicles but not SERCA ATP hydrolysis activity. Int J Biochem Cell Biol 44:801-7.RabbitSkeletal muscle
Cumero 2012 Br J Pharmacol2012Cumero S, Fogolari F, Domenis R, Zucchi R, Mavelli I, Contessi S (2012) F0F1-ATPsynthase as a molecular target of 3-Iodothyronamine. Br J Pharmacol 166:2331-47Heart
Kaambre 2012 J Bioenerg Biomembr2012Kaambre T, Chekulayev V, Shevchuk I, Karu-Varikmaa M, Timohhina N, Tepp K, Bogovskaja J, Kütner R, Valvere V, Saks V (2012) Metabolic control analysis of cellular respiration in situ in intraoperational samples of human breast cancer. J Bioenerg Biomembr 44:539-58.Human
Rat
Heart
Endothelial;epithelial;mesothelial cell
MiPNet08.12 IOC222011-12-11
O2k-Protocols
NO effect on mitochondrial oxygen kinetics at low oxygen. O2k workshop Report.
RatLiver
Niehusmann 2011 Epilepsy Behav2011Niehusmann P, Surges R, von Wrede RD, Elger CE, Wellmer J, Reimann J, Urbach H, Vielhaber S, Bien CG, Kunz WS (2011) Mitochondrial dysfunction due to Leber's hereditary optic neuropathy as a cause of visual loss during assessment for epilepsy surgery. Epilepsy Behav 20:38-43.HumanSkeletal muscle
Nervous system
Perry 2011 Biochem J2011Perry CG, Kane DA, Lin CT, Kozy R, Cathey BL, Lark DS, Kane CL, Brophy PM, Gavin TP, Anderson EJ, Neufer PD (2011) Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle. Biochem J 437:215-22.Human
Rat
Skeletal muscle
Larsen 2011 FASEB J2011Larsen FJ, Schiffer TA, Sahlin K, Ekblom B, Weitzberg E, Lundberg JO (2011) Mitochondrial oxygen affinity predicts basal metabolic rate in humans. FASEB J 25:2843-52.HumanSkeletal muscle
Larsen 2011 Acta Physiol (Oxf)2011Larsen S, Kristensen JM, Stride N, Wojtaszewski JF, Helge JW, Dela F (2011) Skeletal muscle mitochondrial respiration in AMPKα2 kinase-dead mice. Acta Physiol (Oxf) 205: 314-320.MouseSkeletal muscle
Schneider 2010 Gastroenterology2010Schneider M, van Geyte K, Fraisl P, Kiss J, Aragones J, Mazzone M, Mairbaeurl H, Debock K, Ho Jeoung N, Mollenhauer M, Georgiadou M, Bishop T, Roncal C, Sutherland A, Jordan B, Gallez B, Weitz J, Harris RA, Maxwell P, Baes M, Ratcliffe P, Carmeliet P (2010) Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/referpusion injury. Gastroenterology 138:1143-54.MouseSkeletal muscle
Liver
Ziabreva 2010 Glia2010Ziabreva I, Campbell G, Rist J, Zambonin J, Rorbach J, Wydro MM, Lassmann H, Franklin RJ, Mahad D (2010) Injury and differentiation following inhibition of mitochondrial respiratory chain Complex IV in rat oligodendrocytes. Glia 58:1827-37.RatNervous system
Jones 2010 Biochim Biophys Acta2010Jones TT, Brewer GJ (2010) Age-related deficiencies in Complex I endogenous substrate availability and reserve capacity of Complex IV in cortical neuron electron transport. Biochim Biophys Acta 1797:167-76.RatNervous system
Aguirre 2010 Biochim Biophys Acta2010Aguirre E, Rodríguez-Juárez F, Bellelli A, Gnaiger E, Cadenas S (2010) Kinetic model of the inhibition of respiration by endogenous nitric oxide in intact cells. Biochim Biophys Acta 1797:557-65.HEK
Ballot 2010 Apoptosis2010Ballot C, Kluza J, Lancel S, Martoriati A, Hassoun SM, Mortier L, Vienne JC, Briand G, Formstecher P, Bailly C, Nevière R, Marchetti P (2010) Inhibition of mitochondrial respiration mediates apoptosis induced by the anti-tumoral alkaloid lamellarin D. Apoptosis 15:769-81.Human
Lagoutte 2010 Biochim Biophys Acta2010Lagoutte E, Mimoun S, Andriamihaja M, Chaumontet C, Blachier F, Bouillaud F (2010) Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes. Biochim Biophys Acta 1797:1500-11.MouseHeart
Nervous system
Liver
Kidney
CHO
Yang 2010 Cancer Biol Ther2010Yang D, Wang MT, Tang Y, Chen Y, Jiang H, Jones TT, Rao K, Brewer GJ, Singh KK, Nie D (2010) Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L). Canc Biol Ther 9:122-33.MouseFibroblast
Nuskova 2010 J Bioenerg Biomembr2010Nůsková H, Vrbacký M, Drahota Z, Houštěk J (2010) Cyanide inhibition and pyruvate-induced recovery of cytochrome c oxidase. J Bioenerg Biomembr 42:395-403.
Parvez 2010 Biochim Biophys Acta2010Parvez S, Winkler-Stuck K, Hertel S, Schoenfeld P, Siemen D (2010) The dopamine-D2-receptor agonist ropinirole dose-dependently blocks the Ca(2+)-triggered permeability transition of mitochondria. Biochim Biophys Acta 1797:1245-50.RatLiver
Bosworth 2009 Proc Natl Acad Sci U S A2009Bosworth CA, Toledo JC Jr, Zmijewski JW, Li Q, Lancaster JR (2009) Dinitrosyliron complexes and the mechanism(s) of cellular protein nitrosothiol formation from nitric oxide. Proc Natl Acad Sci U S A 106:4671-6.Fungi
Bredholt T 2009 Mol Cancer2009Bredholt T, Dimba EA, Hagland HR, Wergeland L, Skavland J, Fossan KO, Tronstad KJ, Johannessen AC, Vintermyr OK, Gjertsen BT (2009) Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines. Mol Cancer 8:101.HumanBlood cells
Carmona 2009 Int J Obes2009Carmona OMC, Amigó M, Barceló-Batllori S, Julià M, Esteban Y, Moreno S, Gomis R (2009) Dual effects of sodium tungstate on adipocyte biology: Inhibition of adipogenesis and stimulation of cellular oxygen consumption. Int J Obes 33:534-40.
Mantena 2009 Biochem J2009Mantena SK, Vaughn Jr DP, Andringa KK, Eccleston HB, King AL, Abrams GA, Doeller JE, Kraus DW, Darley-Usmar V, Bailey SM (2009) High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo. Biochem J 417:183–93.MouseLiver
Droese 2009 Biochim Biophys Acta2009Dröse S, Hanley PJ, Brandt U (2009) Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain Complexes I and III. Biochim Biophys Acta 1790:558-65.RatHeart
Ripoli 2009 J Virol2009Ripoli M, D'Aprile A, Quarato G, Sarasin-Filipowicz M, Gouttenoire J, Scrima R, Cela O, Boffoli D, Heim MH, Moradpour D, Capitanio N, Piccoli C (2009) Hepatitis C virus-linked mitochondrial dysfunction promotes hypoxia-inducible factor 1{alpha}-mediated glycolytic adaptation. J Virol 84:647-60.HumanLiver
Gellerich 2009 PLoS One2009Gellerich FN, Gizatullina Z, Arandarcikaite O, Jerzembek D, Vielhaber S, Seppet E, Striggow F (2009) Extramitochondrial Ca2+ in the nanomolar range regulates glutamate-dependent oxidative phosphorylation on demand. PloS One 4:e8181.Nervous system
Benani 2009 J Neurosci Methods2009Benani A, Barquissau V, Carneiro L, Salin B, Colombani A-L, Leloup C, Casteilla L, Rigoulet M, Pénicaud L (2009) Method for functional study of mitochondria in rat hypothalamus. J Neurosci Methods 178:301-7.RatNervous system
Skalska 2009 Int J Mol Sci2009Skalska J, Bednarczyk P, Piwonska M, Kulawiak B, Wilczynski G, Dolowy K, Kudin AP, Kunz WS, Szewczyk A (2009) Calcium ions regulate K uptake into brain mitochondria: The evidence for a novel potassium channel. Int J Mol Sci 10:1104-20.RatNervous system
Guachalla 2009 Aging (Albany NY)2009Guachalla LM, Ju Z, Koziel R, Figura G, Song Z, Fusser M, Epe B, Jansen-Dürr P, Rudolph KL (2009) SOD2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice. Aging (Albany NY) 1:303-15.MouseNervous system
Diaz-Ruiz 2008 J Biol Chem2008Díaz-Ruiz R, Avéret N, Araiza D, Pinson B, Uribe-Carvajal S, Devin A, Rigoulet M (2008) Mitochondrial oxidative phosphorylation is regulated by fructose 1,6-bisphosphate. A possible role in Crabtree effect induction? J Biol Chem 283:26948-55.Fungi
Dungel 2008 Arch Biochem Biophys2008Dungel P, Mittermayr R, Haindl S, Osipov A, Wagner C, Redl H, Kozlov AV (2008) Illumination with blue light reactivates respiratory activity of mitochondria inhibited by nitric oxide, but not by glycerol trinitrate. Arch Biochem Biophys 471:109-15.
Brown 2008 Am J Physiol Endocrinol Metab2008Brown AE, Elstner M, Yeaman SJ, Turnbull DM, Walker M (2008) Does impaired mitochondrial function affect insulin signaling and action in cultured human skeletal muscle cells? Am J Physiol Endocrinol Metab 294:E97-102.HumanSkeletal muscle
Hildebrandt 2008 FEBS J2008Hildebrandt TM, Grieshaber MK (2008) Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. FEBS J 275:3352-6.Rat
Annelids
Liver
Tokarska-Schlattner 2007 Biochim Biophys Acta2007Tokarska-Schlattner M, Dolder M, Gerber I, Speer O, Wallimann T, Schlattner U (2007) Reduced creatine-stimulated respiration in doxorubicin challenged mitochondria: Particular sensitivity of the heart. Biochim Biophys Acta 1767:1276-84.HumanHeart
Nervous system
Soller 2007 Mol Pharmacol2007Soller M, Dröse S, Brandt U, Brüne B, von Knethen A (2007) Mechanism of Thiazolidinedione-dependent cell death in Jurkat T cells. Mol Pharmacol 71:1535-44.Heart
Other cell lines
Rodriguez-Juarez 2007 Biochem J2007Rodriguez-Juarez F, Aguirre E, Cadenas S (2007) Relative sensitivity of soluble guanylate cyclase and mitochondrial respiration to endogenous nitric oxide at physiological oxygen concentration. Biochem J 405:223-31.RatFibroblast
Franciso 2007 Eur J Pharmacol2007Franciso R, Perez-Tomas R, Gimenez-Bonafe P, Soto-Cerrato V, Gimenez-Xavier P, Santiago A (2007) Mechanisms of prodigiosin cytotoxicity in human neuroblastoma cell lines. Eur J Pharmacol 572:111-9.HumanNeuroblastoma
Pasdois 2007 Am J Physiol Heart Circ Physiol2007Pasdois P, Quinlan CL, Rissa A, Tariosse L, Vinassa B, Costa AD, Pierre SV, Dos Santos P, Garlid KD (2007) Ouabain protects rat hearts against ischemia-reperfusion injury via pathway involving src kinase, mitoKATP, and ROS. Am J Physiol Heart Circ Physiol 292:H1470-8.RatHeart
Cadenas 2006 Biochim Biophys Acta2006Aguirre E, Rodriguez-Juarez F, Gnaiger E, Cadenas S (2006) Measurement of the control of cellular respiration by nitric oxide under normoxia and hypoxia: instrumental comparison including high-resolution respirometry. Biochim Biophys Acta, EBEC Short Reports Suppl 14:136-7.HumanHEK
Hervouet 2006 Biochem Biophys Res Commun2006Hervouet E, Pecina P, Demont J, Vojtíšková A, Simonnet H, Houštek J, Godinot C (2006) Inhibition of cytochrome c oxidase subunit 4 precursor processing by the hypoxia mimic cobalt chloride. Biochem Biophys Res Commun 344:1086-93.Human
Saccharomyces cerevisiae
Fungi
Le Bourvellec 2004 J Agric Food Chem2004Le Bourvellec C, Le Quéré JM, Sanoner P, Drilleau JF, Guyot S (2004) Inhibition of apple polyphenol oxidase activity by procyanidins and polyphenol oxidation products. J Agric Food Chem 52:122-30.Plants
Rosenfeld 2002 Yeast2002Rosenfeld E, Beauvoit B, Rigoulet M, Salmon JM (2002) Non-respiratory oxygen consumption pathways in anaerobically-grown Saccharomyces cerevisiae: evidence and partial characterization. Yeast 19:1299-321.Saccharomyces cerevisiae
Fungi
Blood cells
Wieser 2001 Biochem J2001Wieser W, Krumschnabel G (2001) Hierarchies of ATP-consuming processes: direct compared with indirect measurements, and comparative aspects. Biochem J 355:389-395.Human
Fishes
Liver
Boveris 1999 Methods Enzymol1999Boveris A, Costa LE, Cadenas E, Poderoso JJ (1999) Regulation of mitochondrial respiration by ADP, O2 and NO. Methods Enzymol 301:188-98.
Sharpe 1998 J Biol Chem1998Sharpe MA, Cooper CE (1998) Interaction of peroxynitrite with mitochondrial cytochrome oxidase: Catalytic production of nitric oxide and irreversible inhibition of enzyme activity. J Biol Chem 273:30961-72.
Gnaiger 1998 BTK-HRR1998Gnaiger E, Kuznetsov AV, Lassnig B, Fuchs A, Reck M, Renner K, Stadlmann S, Rieger G, Margreiter R (1998) High-resolution respirometry. Optimum permeabilization of the cell membrane by digitonin. In BioThermoKinetics in the Post Genomic Era (Larsson C, Pahlman I-L, Gustafsson L, eds) Chalmers Reproservice, Göteborg:89-95.HumanEndothelial;epithelial;mesothelial cell
HUVEC
Kuznetsov 1997 Biochim Biophys Acta1997Kuznetsov AV, Winkler K, Kirches E, Lins H, Feistner H, Kunz WS (1997) Application of inhibitor titrations for the detection of oxidative phosphorylation defects in saponin-skinned muscle fibers of patients with mitochondrial diseases. Biochim Biophys Acta 1360:142-50.Skeletal muscle
O2k-Publications in the MiPMap

O2k-Publications: Inhibitor - Abstracts

Sort in ascending/descending order by a click on one of the small symbols in squares below.
 YearReferenceOrganismTissue;cell
Silva 2019 ESCI20192019Silva FSG, Komlodi T, Garcia-Souza LF, Bento G, Doerrier C, Oliveira PJ, Gnaiger E (2019) Can fatty acid oxidation be specifically blocked by the CPT1 inhibitor etomoxir?Human
Mouse
Liver
Pereira da Silva Grilo da Silva 2018 MiP20182018
Filomena Pereira da Silva Grilo da Silva
The unspecific effect of etomoxir on mitochondrial respiration.
Human
Mouse
Nervous system
Liver
Other cell lines
Komlodi 2017 MiPschool Obergurgl2017
Timea Komlodi
Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H2O2 production.
MouseNervous system
Aasander Frostner 2017 MiP20172017
Åsander Frostner Eleonor
Cell-permeable succinate and malonate as research tools. Aasander Frostner_Poster
HumanHeart
Liver
Blood cells
Fibroblast
Kane 2016 Abstract MitoFit Science Camp 20162016Effects of inhibiting myosin-ATPase on mitochondrial respiratory capacity in permeabilized skeletal muscle.RatSkeletal muscle
Legkun 2014 Abstract IOC 2014-04 Schroecken2014Legkun G, Motovilov K (2014) Investigation on alternative mechanism of electron transport in the respiratory system. Mitochondr Physiol Network 19.02.RatLiver
Sumbalova 2014 Abstract MiP20142014Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain.RatNervous system
Liver
Kressig 2013 Abstract IOC792013Kressig F (2013) et al. Mechanism of increased pulmonary vascular remodeling in UCP2 k/o mice. Mitochondr Physiol Network 18.07MouseLung;gill
Other cell lines
Calzia 2013 Abstract MiP20132013Calzia E, Wagner K, Wagner F, Groeger M, Matallo J, McCook O, Wachter U, Vogt J, Radermacher P (2013) Studying mitochondrial effects of sulfide. Does the species matter? Mitochondr Physiol Network 18.08.Pig
Mouse
Liver
Christen 2013 Abstract MiP20132013Christen F, Desrosiers V, Blier PU (2013) Thermal sensitivity of mitochondria from arctic charr heart: Mitochondrial respiration and ROS production. Mitochondr Physiol Network 18.08.Fishes
Other mammals
Heart
Camacho-Pereira 2013 Abstract IOC752013Camacho-Pereira J (2013) CD38 as a regulator of mitochondrial function. Mitochondr Physiol Network 18.03.MouseHEK
Liver
Macrophage-derived
Palm 2013 Abstract MiP20132013Palm F, Hansell P, Friederich-Persson M (2013) Role of mitochondrial function for the onset and progression of kidney disease. Mitochondr Physiol Network 18.08.Mouse
Rat
Kidney
Wieckowski 2013 Abstract MiP20132013Wieckowski MR, Karkucinska-Wieckowska A, Wojtala A, Lebiedzinska M, Pronicki M, Duszynski J (2013) Mitochondrial bioenergetic parameters, reactive oxygen species production and the status of antioxidant defense system can be used to differentiate mitochondrial defects studied in the fibroblasts from patients with various mitochondrial disorders. Mitochondr Physiol Network 18.08.Human
Mouse
Fibroblast
Pichaud 2013 Abstract MiP20132013Pichaud N, Blier PU(2013) Importance of mitochondrial haplotypes in the expression of metabolic phenotypes under different conditions. Mitochondr Physiol Network 18.08.Drosophila
Hexapods
Skeletal muscle
Bouillaud 2013 Abstract MiP20132013Bouillaud F, Andriamihaja M, Mimoun S, Ransy C, Chaumontet C, Blachier F (2013) Adaptation of mitochondria in colonocytes to hydrogen sulfide exposure. Mitochondr Physiol Network 18.18.Other cell lines
Staples 2013 Abstract MiP20132013Staples JF(2013) Mechanisms of mitochondrial metabolic suppression in hibernation. Mitochondr Physiol Network 18.08.Other mammalsLiver
Tretter 2013 Abstract MiP20132013Tretter L, Komlódi T, Ádám-Vizi V (2013) The effects of methylmalonic acid on alpha-ketoglutarate supported oxidation in isolated brain, heart and liver mitochondria. Mitochondr Physiol Network 18.08.Guinea pigHeart
Nervous system
Liver
Calzia 2012 Abstract Bioblast2012Matallo J, Groeger M, Wachter U, Vogt J, Radermacher P, Calzia E (2012) Interactions between sulfide metabolism and oxygen concentration. Mitochondr Physiol Network 17.12.MouseMacrophage-derived
Bouillaud 2012 Abstract Bioblast2012Bouillaud F (2012) Sulfide - a remarkable mitochondrial substrate. Mitochondr Physiol Network 17.12.HumanCHO
Magnifico 2011 Abstract IOC612011Magnifico MC, Arese M, Mastronicola D, Forte E, Giuffre A, Testa F, Sarti P (2011) NO-signalling and cell bioenergetics. MiPNet16.01.HumanEndothelial;epithelial;mesothelial cell
Silva MiP 20112011Silva da Costa L, Pereira da Silva AP, Da Poian AT, El-Bacha T (2011) Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis Virus: Implications to viral replication and neuronal death. MiP2011.Neuroblastoma
Pinho 2011 Abstract IOC652011Pinho JPC, Goncalves RL, Oliveira MF (2011) Studies on the dynamic changes of mitochondrial function following a blood meal in the kissing bug Rhodnius prolixus. MiPNet16.03.Hexapods
Matallo MiP20102010Matallo J, Reich V, Calzia E, Radermacher P, Groeger M (2010) Interactions between sulfide and mitochondrial respiration in cultured murine alveolar macrophage. Abstract. MiP2010.Lung;gill
Macrophage-derived
Rosenfeld 2010 Abstract IOC602010Rosenfeld E (2010) Abstract IOC60. MiPNet15.10.Saccharomyces cerevisiae
Fungi
Protists
Garedew 2006 Biochim Biophys Acta2006Garedew A, Lemieux H, Schachner T, Blier PU, Tardif J-C, Gnaiger E (2006) High excess capacity of cytochrome c oxidase in permeabilized fibers of the mouse heart. Biochim Biophys Acta, EBEC Short Reports Suppl 14 (2006):167-8.MouseHeart

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 »MitoPedia: Inhibitors
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