Rich 2004 Biochim Biophys Acta

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Rich PR (2004) The quinone chemistry of bc complexes. Biochim Biophys Acta 1658:165-71.

» PMID:15282188 Open Access

Rich PR (2004) Biochim Biophys Acta

Abstract: The quinone chemistry that gives rise to the rather unusual strict bifurcation of electron transfer at the Qo site of the cytochrome bc complexes remains controversial. In this article, I review recent ideas and propose a “logic-gated” binding mechanism that combines classical quinone electrochemistry with specific hydrogen bonding requirements and results in a reversible reaction that minimizes unwanted side-reactions that could otherwise undermine the efficiency of the Q-cycle proton/electron coupling mechanism.

Cited by

  • Komlodi et al (2021) Simultaneous measurement of respiration and redox state of the Coenzyme Q pool in mitochondrial preparations. Bioenerg Commun 2021.3 doi:10.26124/bec:2021-0003

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