Sánchez-Iglesias 2007 J Trace Elem Med Biol

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Sánchez-Iglesias S, Soto-Otero R, Iglesias-Gonzalez J, Barciela-Alonso MC, Bermejo-Barrera P, Méndez-Alvarez E (2007) Analysis of brain regional distribution of aluminium in rats via oral and intraperitoneal administration. J Trace Elem Med Biol 21:31-4.

» PMID:18039493

Sánchez-Iglesias S, Soto-Otero R, Iglesias-Gonzalez J, Barciela-Alonso MC, Bermejo-Barrera P, Méndez-Alvarez E (2007) J Trace Elem Med Biol

Abstract: In the present work, accumulation and distribution of aluminium in the rat brain following both intraperitoneal and oral administration were studied. Electrothermal atomic absorption spectrometry was used to determine aluminium concentration in different brain areas (cerebellum, ventral midbrain, cortex, hippocampus, and striatum). Most of the brain areas showed accumulation of aluminium, but a greater and more significant increase was noted in the group receiving aluminium via intraperitoneal administration. Aluminium distribution was also dependent on the administration route.


Bioblast editor: Iglesias-Gonzalez J O2k-Network Lab: AT Innsbruck Oroboros, ES Santiago De Compostela Mendez-Alvarez E, UK Manchester Galli GL


Labels: MiParea: Pharmacology;toxicology  Pathology: Parkinson's 

Organism: Rat  Tissue;cell: Nervous system