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From Bioblast

DatLab 7.3 2018-07-12

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DatLab

DatLab 7.3 release


We are proud to release DatLab 7.3, optimized for the Oroboros O2k-Series H, and enhancing applications of all O2k configurations. The software includes numerous new features:


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  • Calibration and flux analysis – simplified for O2k-FluoRespirometer channels and add-on O2k-Modules.
  • DatLab Protocols: Both (1) instrumental protocols for quality control and (2) experimental substrate-uncoupler-inhibitor (SUIT) protocols guide the user step-by-step through the experiment, with programmed Events (titrations) and Marks (sections of the experiment for statistical analysis).
  • Browse DL-Protocols and templates: In a library of standardized protocols, each SUIT protocol is explained by an application example and supported by a template for data analysis.
  • Lower O2 limit: Respiration becomes oxygen dependent below a critical oxygen concentration. An automatic warning alerts the user to avoid hypoxia.
  • Graphs: Standard graph layouts can be selected, adjusted, and saved as User-defined layouts, to view O2k-MultiSensor experiments and export graphs for publication. Titration-induced peaks and spikes can be deleted.
  • Mark statistics: New statistical features are available for numerical display of results from DL-Protocol Marks and user-defined marks: median, average, SD, outlier index. These data can be exported for further analysis.



TRACT

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TRACT Open PhD position - unique opportunities

  • Marie-Sklodlowska Curie project
  • PhD position in cancer research with focus on mitochondrial function
  • Two labs - one team: 25 O2k instruments (50 chambers) in action for High-Resolution FluoRespirometry (respiration, hydrogenperoxide production, mt-membrane potential, ADP-ATP phosphorylation, pH, Ca2+)
  • Unique prototypes for research: Q2k with Coenzyme Q redox sensor / NextGen-O2k with NADH autofluorescence, spectrophotometry for cytochrome redox state, ratiometric spectrofluorometry / O2kinetics software for analysis of oxygen kinetics of mitochondrial respiration
  • More details: TRACT