Thyfault John P

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Thyfault John P


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1


Name Thyfault John, PhD
Institution The Department of Molecular & Integrative Physiology,

University of Kansas, US

Address 2067 Hemenway

3901 Rainbow Blvd., 66160

City Kansas City
State/Province Kansas (KS)
Country USA
Email jthyfault@kumc.edu
Weblink
O2k-Network Lab US KS Kansas City Thyfault JP


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Publications

 PublishedReference
Martino 2024 Am J Physiol Endocrinol Metab2024Martino MR, Habibi M, Ferguson D, Brookheart RT, Thyfault JP, Meyer GA, Lantier L, Hughey CC, Finck BN (2024) Disruption of hepatic mitochondrial pyruvate and amino acid metabolism impairs gluconeogenesis and endurance exercise capacity in mice. Am J Physiol Endocrinol Metab 326:E515-27. https://doi.org/10.1152/ajpendo.00258.2023
Kugler 2023 J Appl Physiol (1985)2023Kugler BA, Thyfault JP, McCoin CS (2023) Sexually dimorphic hepatic mitochondrial adaptations to exercise: a mini-review. J Appl Physiol (1985) 134:685-91. https://doi.org/10.1152/japplphysiol.00711.2022
Fuller 2020 J Appl Physiol (1985)2020Fuller KNZ, McCoin CS, Allen J, Bell-Glenn S, Koestler DC, Dorn Ii GW, Thyfault JP (2020) Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice. J Appl Physiol (1985) 128:1251-61.
BEC 2020.1 doi10.26124bec2020-0001.v12020Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
McCoin 2019 Am J Physiol Endocrinol Metab2019McCoin CS, Von Schulze A, Allen J, Fuller KN, Xia Q, Koestler DC, Houchen CJ, Maurer A, Dorn Ii GW, Shankar K, Morris EM, Thyfault JP (2019) Sex modulates hepatic mitochondrial adaptations to high fat diet and physical activity. Am J Physiol Endocrinol Metab 317:E298-E311.
Cooper 2019 Exp Physiol2019Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE (2019) Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12.
Von Schulze 2018 J Physiol2018Von Schulze A, McCoin CS, Onyekere C, Allen J, Geiger P, Dorn GW, Morris EM, Thyfault JP (2018) Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1Ξ±, and BNIP3 mediated mitophagy. J Physiol 596:6157-71.
Cooper 2018 Exp Physiol2018Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE (2018) Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12.
Linden 2016 Am J Physiol Gastrointest Liver Physiol2017Linden MA, Fletcher JA, Meers GM, Thyfault JP, Laughlin MH, Rector RS (2017) A return to ad libitum feeding following caloric restriction promotes hepatic steatosis in hyperphagic OLETF rats. Am J Physiol Gastrointest Liver Physiol 311:G387-95.
Aroor 2015 Diabetes2015Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001.
Fletcher 2014 Med Sci Sports Exerc2014Fletcher JA, Meers GM, Linden MA, Kearney ML, Morris EM, Thyfault JP, Rector RS (2014) Impact of various exercise modalities on hepatic mitochondrial function. Med Sci Sports Exerc 46:1089-97.
Rector 2010 J Hepatol2010Rector RS, Thyfault JP, Uptergrove GM, Morris EM, Naples SP, Borengasser SJ, Mikus CR, Laye MJ, Laughlin MH, Booth FW, Ibdah JA (2010) Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model. J Hepatol 52:727-36.

Abstracts

 PublishedReference
Morris 2015 Abstract MiPschool Greenville 20152015Intrinsic high aerobic capacity is associated with protection of mitochondrial respiratory capacity and decreased inflammation following chronic high-fat/high-cholesterol diet challenge.
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