US MO St Louis Abumrad NA

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US MO St Louis Abumrad NA

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Department of Medicine and Cell Biology

Center for Human Nutrition

Power-O2k Network Cluster: US MO St Louis School of Medicine

Address Campus Box 8031

660 S. Euclid Ave.

212 West Building, 63110

City St. Louis
State/Prov Missouri (MO)
Country USA
Weblink
Contact Abumrad Nada A
Team Flynn Robb, Pietka Terri A, Schappe Timothy
Team previous
Status O2k 2010-
Oroboros Events IOC55
Topics


O2k-Publications

 PublishedReference
Zhang 2024 Cell Metab2024Zhang Y, Higgins CB, Tica S, Adams JA, Sun J, Kelly SC, Zong X, Dietzen DJ, Pietka T, Ballentine SJ, Shriver L, Patti G, Cao Y, DeBosch BJ (2024) Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism. Cell Metab [Epub ahead of print]. https://doi.org/10.1016/j.cmet.2024.07.007
Kim 2023 bioRxiv2023Kim Y, Li C, Gu C, Tycksen E, Puri A, Pietka TA, Sivapackiam J, Fang Y, Kidd K, Park SJ, Johnson BG, Kmoch S, Duffield JS, Bleyer AJ, Jackrel ME, Urano F, Sharma V, Lindahl M, Chen YM (2023) MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathy. https://doi.org/10.1101/2023.01.10.523171
Mousa 2023 Cell Rep2023Mousa MG, Vuppaladhadiam L, Kelly MO, Pietka T, Ek S, Shen KC, Meyer GA, Finck BN, Brookheart RT (2023) Site-1 protease inhibits mitochondrial respiration by controlling the TGF-Ξ² target gene Mss51. Cell Rep 42:112336. https://doi.org/10.1016/j.celrep.2023.112336
Kim 2023 Nat Commun2023Kim Y, Li C, Gu C, Fang Y, Tycksen E, Puri A, Pietka TA, Sivapackiam J, Kidd K, Park SJ, Johnson BG, Kmoch S, Duffield JS, Bleyer AJ, Jackrel ME, Urano F, Sharma V, Lindahl M, Chen YM (2023) MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice. Nat Commun 14:6493. https://doi.org/10.1038/s41467-023-42154-0
Yoshino 2021 Science2021Yoshino M, Yoshino J, Kayser BD, Patti GJ, Franczyk MP, Mills KF, Sindelar M, Pietka T, Patterson BW, Imai SI, Klein S (2021) Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science 372:1224-29. https://doi.org/10.1126/science.abe9985
Jacome-Sosa 2021 Commun Biol2021Jacome-Sosa M, Miao ZF, Peche VS, Morris EF, Narendran R, Pietka KM, Samovski D, Lo HG, Pietka T, Varro A, Love-Gregory L, Goldenring JR, Kuda O, Gamazon ER, Mills JC, Abumrad NA (2021) CD36 maintains the gastric mucosa and associates with gastric disease. Commun Biol 4:1247. https://doi.org/10.1038/s42003-021-02765-z
Bittel 2021 Diabetes2021Bittel DC, Bittel AJ, Varadhachary AS, Pietka T, Sinacore DR (2021) Deficits in the skeletal muscle transcriptome and mitochondrial coupling in progressive diabetes-induced CKD relate to functional decline. Diabetes 70:1130-44. https://doi.org/10.2337/db20-0688
Bittel 2019 Diabetologia2019Bittel AJ, Bittel DC, Mittendorfer B, Patterson BW, Okunade AL, Yoshino J, Porter LC, Abumrad NA, Reeds DN, Cade WT (2019) A single bout of resistance exercise improves postprandial lipid metabolism in overweight/obese men with prediabetes. Diabetologia 63:611-23.
Mayer 2018 Endocrinology2018Mayer AL, Zhang Y, Feng EH, Higgins CB, Adenekan O, Pietka TA, Beatty WL, DeBosch BJ (2018) Enhanced hepatic PPARΞ± activity links GLUT8 deficiency to augmented peripheral fasting responses in male mice. Endocrinology 159:2110-26.
Park 2018 J Clin Invest2018Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ (2018) Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest 129:694-711.
Harris 2015 Diabetes2015Harris LA, Skinner JR, Shew TM, Pietka TA, Abumrad NA, Wolins NE (2015) Perilipin 5-driven lipid droplet accumulation in skeletal muscle stimulates the expression of fibroblast growth factor 21. Diabetes 64:2757-68.
Mancuso 2010 J Biol Chem2010Mancuso DJ, Sims HF, Yang K, Kiebish MA, Su X, Jenkins CM, Guan S, Moon SH, Pietka T, Nassir F, Schappe T, Moore K, Han X, Abumrad NA, Gross RW (2010) Genetic ablation of calcium-independent phospholipase A2{gamma} prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation. J Biol Chem 285:36495-510.

O2k-Abstracts

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  • Our O2ks Rosie and Rupert returned to service today. The best kind of equipment is the reliable, robust, low maintenance kind. Terri Pietka (2020-09-16).
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