From Bioblast
US VA Richmond Iyer S
| O2k-Network Lab |  Center for the Study of Biological Complexity Life Sciences Program |
|---|---|
| Address | Office number 3139, Harris Hall,
Virginia Commonwealth University, 23284 |
| City | Richmond |
| State/Prov | Virginia (VA) |
| Country | USA |
| Weblink | |
| Contact | |
| Team | |
| Team previous | Bennett James P, Iyer Shilpa, Rao Raj R, Surampudi Vasudha |
| Status | O2k 2012-2016; present: US AR Fayetteville Iyer S |
| Oroboros Events | MitoEAGLE 2017 CZ, MiPschool 2017, MiP2014, Bioblast 2012, IOC77, IOC72, IOC54 |
| Topics | Mitochondrial diseases, Stem Cells, Respiration |
O2k-Publications
| Published | Reference | |
|---|---|---|
| Thomas 2016 Neurodegeneration Therapeutics | 2016 | Thomas RR, Keeney PM, Berr SB, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Brohawn DG, Bennett JP (2016) Recombinant human TFAM stimulates rat brain, rat cervical spinal cord and human neural stem cell mitochondrial bioenergetics. Neurodegeneration Therapeutics p41. |
| Iyer 2012 Hum Gene Ther | 2012 | Iyer S, Bergquist K, Young K, Gnaiger E, Rao RR, Bennett JP Jr (2012) Mitochondrial gene therapy improves respiration, biogenesis and transcription in G11778A Leber’s hereditary optic neuropathy and T8993G Leigh’s syndrome cells. Hum Gene Ther 23:647-57. |
| Thomas 2011 Mitochondrion | 2011 | Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr (2011) Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18. |
| Borland 2009 Biochim Biophys Acta | 2009 | Borland MK, Mohanakumar KP, Rubinstein JD, Keeney PM, Xie J, Capaldi R, Dunham LD, Trimmer PA, Bennett JP Jr (2009) Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues. Biochim Biophys Acta 792: 68-74. |
| Iyer 2009 Mitochondrion | 2009 | Iyer S, Thomas R, Portell F, Dunham L, Quigley C, Bennett JP (2009) Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression. Mitochondrion 9:196-203. |
| Keeney 2009 Hum Gene Ther | 2009 | Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP (2009) Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther 20:897-907. |
| Keeney 2009 Exp Neurol | 2009 | Keeney PM, Dunham LD, Quigley CK, Morton SL, Bergquist KE, Bennett JP (2009) Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships. Exp Neurol 220:374-82. |
| Iyer 2008 Nature Precedings | 2008 | Iyer S, Thomas R, Portell F, Dunham L, Quigley C, Bennett JP (2008) Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression in G11778A leber’s hereditary optic neuropathy cybrid cells. Nature Precedings: hdl:10101/npre.2008.2084.1 |
O2k-Abstracts
| Published | Reference | |
|---|---|---|
| Iyer 2012 Abstract Bioblast | 2012 | Iyer S (2012) Gentle Science in the real world of mitochondrial physiology and genetics. Mitochondr Physiol Network 17.12. |
Gentle Science
- Iyer S, Faris S, Rao R, Jamison R, Maurakis E (2014) Bioenergetics: arts meets gentle science in sickness and in health. In: Laner V, Gnaiger E, eds. Mitochondrial physiology – methods, concepts and biomedical perspectives. MiP2014. Mitochondr Physiol Network 19.13. >>Open Access
Exhibition
Videos
- Bioenergetics Movie final (August 2014)
- Bioenergetics #3 (July 2014)
- Bioenergetics #2 (July 2014)
Seminar 2015-03-16
MITOCHONDRIAL PHYSIOLOGY AND OPEN INNOVATION: Science, Development and Enterprise
This seminar is a 'guided walk' through the Bioblast website, explaining high-resolution respirometry and the concept of the Oroboros Instruments company.
Feedback
- The Bioblast alert is wonderful!! Thank you so much. I am grateful for your support and for promoting gentle science in all you do. Shilpa Iyer (2015-01-15)
