ZA Cape Town Ojuka EO

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ZA Cape Town Ojuka EO

Oroboros O2k-Network

O2k-Network
O2k-Network Lab
Ojuka EO - Power O2k

Institute of South Africa Newlands

ESSM UCT Dept of Human Biology Sports Science

University of Cape Town

Address Boundary Road, Newlands, 7700
City Cape Town
State/Prov
Country South Africa
Weblink Ojuka E
Contact Ojuka Edward O, O2k-Network Manager South Africa
Team
Team previous Goyaram Veeraj, Imbriolo Jamie, Andrew Brittany, Bezuidenhout Nicole, Feldmann Daneil, George Siddiqah, Kohn Tertius, Leith David, Maarman Gerald, Madlala Hlengiwe, Mendham Amy, Osiki Prisca, Smith James, Webster Christopher
Status 2 Power-O2k 2013-2017; present: ZA Cape Town Smith J
Oroboros Events IOC122, MiPschool 2017, MitoFit Science Camp 2016, IOC106, MiPschool 2015, IOC99, IOC96, MiP2014, IOC90, IOC68
Topics


O2k-Publications

 PublishedReference
Driescher 2019 Heliyon2019Driescher N, Joseph DE, Human VR, Ojuka E, Cour M, Hadebe N, Bester D, Marnewick JL, Lecour S, Lochner A, Essop MF (2019) The impact of sugar-sweetened beverage intake on rat cardiac function. Heliyon 5:e01357.
Kriel 2018 Sci Rep2018Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348.
Enhancing physiological understanding of exercise and obesity: designing personalised intervention strategies 2017 Stellenbosch ZA2017-01-30Stellenbosch ZA, 2017 Jan 30-Feb 02. Enhancing physiological understanding of exercise and obesity: designing personalised intervention strategies.
Ojuka 2016 Am J Physiol Endocrinol Metab2016Ojuka E, Andrew B, Bezuidenhout N, George S, Maarman G, Madlala HP, Mendham A, Osiki PO (2016) Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. Am J Physiol Endocrinol Metab 310:E715-23.
Maarman 2016 J Appl Physiol (1985)2016Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes. J Appl Physiol (1985) 122:1003-10.
Osiki 2016 FASEB J2016Osiki PO, Ojuka E, Marmaan G (2016) An investigation of the suitability of using octanoylcarnitine together with malate as a substrate combination for assessing Beta-oxidation using High Resolution Respirometry. FASEB J 30: 1015.12 .
MiPNet20.02 IOC99 Cape Town2015-03-23
O2k-Network
Cape Town ZA, 2015 Mar 23-24. Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC99. - Satellite to 7th MiPschool Cape Town 2015.

O2k-Abstracts

 PublishedReference
Madlala 2016 Abstract MitoFit Science Camp 20162016Fructose-induced defects in selected mitochondrial enzymes is detected by respirometry using glutamate&malate but not pyruvate&malate substrates.
Maarman 2016 Abstract MitoFit Science Camp 20162016Melatonin rescues uric acid-induced impairment of respiration in myotubes.
Bezuidenhout 2016a Abstract MitoFit Science Camp 20162016Comparison of oxygen dependence of respiration in permeabilized mouse skeletal muscle fibers in two respiration media, MiR06Cr and Buffer Z containing Ctl, Cr and Blebbistatin.
Osiki 2016 Abstract MitoFit Science Camp 20162016Suitability of octanoylcarnitine & malate for assessment of beta oxidation capacity by respirometry in aconitase-inhibited samples.
George 2015 Abstract MiPschool Cape Town 20152015Regulation of LCAD and SIRT3 activities by NAD+ in skeletal muscle of fructose-fed rats.
Madlala 2015 Abstract MiPschool Cape Town 20152015Fructose-induced ROS production: The role of uric acid and transforming growth factor (TGF)-β1.
Ojuka 2015 Abstract MiPschool Cape Town 20152015Use of malate or carnitine as co-substrates for assessment of fatty acid oxidation.
Bezuidenhout 2015 Abstract MiPschool Cape Town 20152015A study of the effects of fructose feeding & exercise on SIRT 3 regulation in skeletal muscle.
K-Regio MitoFit

MitoFit

Strategic partner of the K-Regio MitoFit project.


O2k-Network Manager

Siddiqah George, MSc. is the OroborosO2k-Network Manager South Africa.



Visiting scientist in the Oroboros MitoFit Laboratory

O2k-Network

Nicole Bezuidenhout: Visiting scientist at the Oroboros MitoFit Laboratory from October 05 to November 30 2015.


"Open day" at the Institute of South Africa Newlands - September 2015


IOC99 O2k-Workshop 2015-03-23 to 24


Public lecture 2015-03-20, 01:00 pm

Erich Gnaiger (Austria) SCIENCE AND ADVENTURE. The World as a Laboratory: Exploring Mitochondrial Fitness
Erich Gnaiger, Professor at the Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery at the Medical University of Innsbruck, Austria, and CEO of Oroboros Instruments, will share some of his experiences in the many expeditions he and his team have undertaken to investigate mitochondrial function at extreme conditions: These studies have included (a) analysis of Alaskan huskies before and after the 1,100 miles long Iditarod race, b) OXPHOS analysis and acclimation of muscle mitochondria at the Everest base camp located 5,364 m above sea level, c) evaluation of mitochondrial fitness in permeabilized muscle fibers obtained from traditional lifestyle Inuit hunters in Northern Greenland compared to Western lifestyle Inuits and Danish participants of the 42-days expedition.
Erich Gnaiger, who is the president of the Mitochondrial Physiology Society, will be a guest of the University of Cape Town from March 20th – 27th to conduct an O2k-Workshop on high-resolution respirometry using the Oroboros Oxygraph-2k and speak at the Mitochondrial Physiology School organized by Associate Professor Edward Ojuka of the Exercise Science and Sports medicine research group.