ZA Cape Town Smith J

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ZA Cape Town Smith J

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Dept Human Biology

University of Cape Town

Sports science Institute

Address Boundary Rd, Newlands, 7945
City Cape Town
State/Prov
Country South Africa
Weblink
Contact Smith James
Team Andrew Brittany, Feldmann Daneil, George Siddiqah, Leith David, Maarman Gerald, Madlala Hlengiwe, Mendham Amy, Osiki Prisca, Webster Christopher
Team previous Bezuidenhout Nicole
Status 2 Power-O2k 2013-; previous: ZA Cape Town Ojuka EO
Oroboros Events MitoEAGLE 2018 LV, MiPschool 2017, IOC122, MitoFit Science Camp 2016, IOC106, MiPschool 2015, IOC99, IOC96, MiP2014, IOC95
Topics


O2k-Publications

 PublishedReference
Kriel 2018 Sci Rep2018Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348.
Victor 2017 Thesis2017Victor L (2017) Investigating the possible cytoprotective effects of melatonin isomer against simulated ischemic injury. Master's Thesis 76.
Osiki 2016 FASEB J2016Osiki PO, Ojuka E, Marmaan G (2016) An investigation of the suitability of using octanoylcarnitine together with malate as a substrate combination for assessing Beta-oxidation using High Resolution Respirometry. FASEB J 30: 1015.12 .
Ojuka 2016 Am J Physiol Endocrinol Metab2016Ojuka E, Andrew B, Bezuidenhout N, George S, Maarman G, Madlala HP, Mendham A, Osiki PO (2016) Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. Am J Physiol Endocrinol Metab 310:E715-23.

O2k-Abstracts

 PublishedReference
Bezuidenhout 2016a Abstract MitoFit Science Camp 20162016Comparison of oxygen dependence of respiration in permeabilized mouse skeletal muscle fibers in two respiration media, MiR06Cr and Buffer Z containing Ctl, Cr and Blebbistatin.
Bezuidenhout 2016b Abstract MitoFit Science Camp 20162016Analysis and comparison of mitochondrial function using cooling plate or ice during mechanical separation of mouse skeletal muscle fibers.
Osiki 2016 Abstract MitoFit Science Camp 20162016Suitability of octanoylcarnitine & malate for assessment of beta oxidation capacity by respirometry in aconitase-inhibited samples.
Madlala 2016 Abstract MitoFit Science Camp 20162016Fructose-induced defects in selected mitochondrial enzymes is detected by respirometry using glutamate&malate but not pyruvate&malate substrates.
Maarman 2016 Abstract MitoFit Science Camp 20162016Melatonin rescues uric acid-induced impairment of respiration in myotubes.
Madlala 2015 Abstract MiPschool Cape Town 20152015Fructose-induced ROS production: The role of uric acid and transforming growth factor (TGF)-β1.
Ojuka 2015 Abstract MiPschool Cape Town 20152015Use of malate or carnitine as co-substrates for assessment of fatty acid oxidation.
Bezuidenhout 2015 Abstract MiPschool Cape Town 20152015A study of the effects of fructose feeding & exercise on SIRT 3 regulation in skeletal muscle.
George 2015 Abstract MiPschool Cape Town 20152015Regulation of LCAD and SIRT3 activities by NAD+ in skeletal muscle of fructose-fed rats.
Maarman 2015 Abstract MiPschool Cape Town 20152015Characterisation of mitochondrial function in a model of pulmonary hypertension-induced right ventricular failure.