Difference between revisions of "Carnitine"
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Long-chain fatty acids are activated by an energy-requiring step in which the fatty acid ester of CoA is formed enzymatically at the expense of ATP. The fatty acids then pass through teh inner membrane and enter the mitochondria as esters of the compound carnitine. The fatty acyl group is then transferred from carnitine to intramitochondrial CoA and the resulting fatty acyl CoA is then used as a substrate by the fatty acid oxidation cycle, which occurs in the inner matrix compartment. | |||
Revision as of 16:10, 21 May 2012
- high-resolution terminology - matching measurements at high-resolution
Carnitine
Description
Carnitine has a stimulating effect on the oxidation of fatty acids by mitochondria.
MitoPedia topics: Substrate and metabolite
Long-chain fatty acids are activated by an energy-requiring step in which the fatty acid ester of CoA is formed enzymatically at the expense of ATP. The fatty acids then pass through teh inner membrane and enter the mitochondria as esters of the compound carnitine. The fatty acyl group is then transferred from carnitine to intramitochondrial CoA and the resulting fatty acyl CoA is then used as a substrate by the fatty acid oxidation cycle, which occurs in the inner matrix compartment.
