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DTPA

From Bioblast


high-resolution terminology - matching measurements at high-resolution


DTPA

Description

DTPA (Diethylentriamin-N,N,N',N,N-pentaacetic acid, pentetic acid) is a chelator of transition metals, not cell membrane permeable. general chelates multivalent ions stronger than EDTA; pKa1 = 2.14, pKa2 = 2.38, pKa3 = 4.26 pKa4 = 8.60, pKa5 = 10.53

Abbreviation: DTPA


Description

  • CAS: 67-43-6
  • Source: EHRENSTORFER GMBH (EHERE13095000) or Sigma Aldrich (D-1133).
  • FW: 393.35
  • Solubility in H2O: ~ 4,8 g/l at 25 Β°C = 12 mM
  • Stability constant: see: [1]:
Metal DTPA EDTA
Ca(II) 10.74 10.96
Mg(II) 9.3 8.69
Fe(II) 16.5 14.3
Fe(III) 28.6 25.1
Mn(II) 15.6 14.04
Zn (II) 18.75 16.5


DTPA in O2k-FluoRespirometry

  • Final concentration in O2k-chamber: 15 Β΅M
  • Stock solution: