FI Helsinki Mervaala E
| O2k-Network Lab | Institute of Biomedicine, Pharmacology
Biomedicum Helsinki University of Helsinki |
|---|---|
| Address | P.O. BOX 63
Haartmaninkatu 8, FI-00014 |
| City | Helsinki |
| State/Prov | |
| Country | Finland |
| Weblink | |
| Contact | Mervaala Eero |
| Team | Bechara-Hirvonen Nada, Kallijaervi Jukka, Kankuri Esko, Lapatto Risto, Purhonen Janne |
| Team previous | |
| Status | O2k 2011- |
| Oroboros Events | IOC100, MiP2014, IOC93, IOC75 |
| Topics |
O2k-Publications
| Published | Reference | |
|---|---|---|
| Kankuri 2023 Exp Mol Med | 2023 | Kankuri E, Finckenberg P, Leinonen J, Tarkia M, Björk S, Purhonen J, KallijÀrvi J, Kankainen M, Soliymani R, Lalowski M, Mervaala E (2023) Altered acylcarnitine metabolism and inflexible mitochondrial fuel utilization characterize the loss of neonatal myocardial regeneration capacity. https://doi.org/10.1038/s12276-023-00967-5 |
| Purhonen 2020 Nat Commun | 2020 | Purhonen J, Grigorjev V, Ekiert R, Aho N, Rajendran J, Pietras R, Truvé K, Wikström M, Sharma V, Osyczka A, Fellman V, KallijÀrvi J (2020) A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice. Nat Commun 11:322. |
| Rajendran 2019 EMBO Mol Med | 2019 | Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Auvinen P, Mervaala E, Jacobs HT, Szibor M, Fellman V, KallijÀrvi J (2019) Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy. EMBO Mol Med 11:e9456. |
| Tomasic 2019 Biochim Biophys Acta Mol Basis Dis | 2019 | TomaĆĄiÄ N, Kotarsky H, de Oliveira Figueiredo R, Hansson E, Mörgelin M, TomaĆĄiÄ I, KallijĂ€rvi J, ElmĂ©r E, Jauhiainen M, Eklund EA, Fellman V (2019) Fasting reveals largely intact systemic lipid mobilization mechanisms in respiratory chain complex III deficient mice. Biochim Biophys Acta Mol Basis Dis 1866:165573. |
| Tegelberg 2017 Orphanet J Rare Dis | 2017 | Tegelberg S, TomaĆĄiÄ N, KallijĂ€rvi J, Purhonen J, ElmĂ©r E, Lindberg E, Nord DG, Soller M, Lesko N, Wedell A, Bruhn H, Freyer C, Stranneheim H, Wibom R, Nennesmo I, Wredenberg A, Eklund EA, Fellman V (2017) Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model. Orphanet J Rare Dis 12:73. |
| Nelskylae 2017 Resuscitation | 2017 | NelskylÀ A, Nurmi J, Jousi M, Schramko A, Mervaala E, Ristagno G, Skrifvars MB (2017) The effect of 50% compared to 100% inspired oxygen fraction on brain oxygenation and post cardiac arrest mitochondrial function in experimental cardiac arrest. Resuscitation 116:1-7. |
| Raesaenen 2016 Proc Natl Acad Sci U S A | 2016 | RÀsÀnen M, Degerman J, Nissinen TA, Miinalainen I, KerkelÀ R, Siltanen A, Backman JT, Mervaala E, Hulmi JJ, KivelÀ R, Alitalo K (2016) VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection. Proc Natl Acad Sci U S A 113:13144-49. |
| Heinonen 2016 Hum Exp Toxicol | 2016 | Heinonen JA, Schramko AA, Skrifvars MB, Litonius E, Backman JT, Mervaala E, Rosenberg PH (2016) The effects of intravenous lipid emulsion on hemodynamic recovery and myocardial cell mitochondrial function after bupivacaine toxicity in anesthetized pigs. Hum Exp Toxicol 36:365-75. |
| Nissinen 2016 Sci Rep | 2016 | Nissinen TA, Degerman J, RÀsÀnen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, KivelÀ R, Hulmi JJ (2016) Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Sci Rep 6:32695. |
| Den Hollander 2014 Toxicol Sci | 2014 | den Hollander B, Sundström M, Pelander A, OjanperÀ I, Mervaala E, Korpi ER, Kankuri E (2014) Keto amphetamine toxicity - focus on the redox reactivity of the cathinone designer drug mephedrone. Toxicol Sci 141:120-31. |
| Kivelae 2014 EMBO Mol Med | 2014 | KivelÀ R, Bry M, Robciuc MR, RÀsÀnen M, Taavitsainen M, Silvola JM, Saraste A, Hulmi JJ, Anisimov A, MÀyrÀnpÀÀ MI, Lindeman JH, Eklund L, Hellberg S, Hlushchuk R, Zhuang ZW, Simons M, Djonov V, Knuuti J, Mervaala E, Alitalo K (2016) VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO Mol Med 6:307-21. |
O2k-Abstracts
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- I was participating last summer in WorldPharma 2010 congress in Copenhagen and heard a fantastic presentation given by Professor Sir Salvador Moncada about mitochondrial function measured by OROBOROS Oxygraph. - Eero Mervaala (2010)
