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Difference between revisions of "Flux control ratio"

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|abbr=''FCR''
|abbr=''FCR''
|description='''Flux control ratios''' (''FCR''), are ratios of oxygen flux in different respiratory control states, normalized for maximum flux in a common reference state, to obtain theoretical lower and upper limits of 0.0 and 1.0 (0% and 100%). ''FCR'' obtained from a single respirometric incubation (sequential protocol; [[SUIT protocol]]) provide an internal normalization, expressing respiratory control independent of mitochondrial content and thus independent of a marker for mitochondrial amount. ''FCR'' obtained from separate (parallel) protocols depend on determination of a common [[mitochondrial marker]].
|description='''Flux control ratios''' (''FCR''), are ratios of oxygen flux in different respiratory control states, normalized for maximum flux in a common reference state, to obtain theoretical lower and upper limits of 0.0 and 1.0 (0% and 100%). ''FCR'' obtained from a single respirometric incubation (sequential protocol; [[SUIT protocol]]) provide an internal normalization, expressing respiratory control independent of mitochondrial content and thus independent of a marker for mitochondrial amount. ''FCR'' obtained from separate (parallel) protocols depend on determination of a common [[mitochondrial marker]].
|info=[[MiPNet12.15]], [[Gnaiger_2009_IJBCB]], [[Pesta_2010_Protocols]]
|info=[[MiPNet12.15]], [[Gnaiger_2009_IJBCB]], [[Pesta 2012 Methods Mol. Biol.]]
|type=Respiration
|type=Respiration
}}
}}

Revision as of 15:34, 17 November 2011


high-resolution terminology - matching measurements at high-resolution


Flux control ratio

Description

Flux control ratios (FCR), are ratios of oxygen flux in different respiratory control states, normalized for maximum flux in a common reference state, to obtain theoretical lower and upper limits of 0.0 and 1.0 (0% and 100%). FCR obtained from a single respirometric incubation (sequential protocol; SUIT protocol) provide an internal normalization, expressing respiratory control independent of mitochondrial content and thus independent of a marker for mitochondrial amount. FCR obtained from separate (parallel) protocols depend on determination of a common mitochondrial marker.

Abbreviation: FCR

Reference: MiPNet12.15, Gnaiger_2009_IJBCB, Pesta 2012 Methods Mol. Biol.


MitoPedia methods: Respirometry 


MitoPedia topics: "Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory state"Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.