Garcia JA

Name	,
Institution
Address	,
City
State/Province
Country
Email
Weblink
O2k-Network Lab

Labels:

Publications

	Published	Reference
Volt 2016 J Pineal Res	2016	Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.
Doerrier 2016 Mitochondrion	2016	Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63.
Garcia 2015 FASEB J	2015	García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75.
Ortiz 2015 J Pineal Res	2015	Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.
Doerrier 2014 Life Sci	2014	Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.
Ortiz 2014 J Pineal Res	2014	Ortiz F, García JA, Acuña-Castroviejo D, Doerrier C, López A, Venegas C, Volt H, Luna-Sánchez M, López LC, Escames G (2014) The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81.
Garcia-Corzo 2013 Hum Mol Genet	2013	García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48.
Acuña-Castroviejo 2011 Curr Top Med Chem	2011	Acuña-Castroviejo D; López LC; Escames G; López A; García JA; Reiter RJ (2011) Melatonin-mitochondria interplay in health and disease. Curr Top Med Chem 11:221-240.
Lopez 2009 J Pineal Res	2009	López A, García JA, Escames G, Venegas C, Ortiz F, López LC, Acuña-Castroviejo D (2009) Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production. J Pineal Res 46:188-98.

Abstracts

	Published	Reference
Luna-Sánchez 2014 Abstract SECF	2014	Mitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment.
Volt 2014 Abstract SECF	2014	Experimental basis for the “inflammaging” theory.
Garcia 2014 Abstract SECF	2014	Melatonin disrupts the NF-κB/NLRP3 connection in sepsis through RORα receptor.
Diaz-Casado 2014 Abstract SECF	2014	Melatonin restores mitochondrial regulatory gene expression and function in the zebrafish model of parkinsonism.
Volt 2014 Abstract The 2014 Ageing Summit	2014	Effects of melatonin on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis.
Doerrier 2014 Abstract SECF	2014	Evaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice.
Doerrier 2012 Abstract Bioblast	2012	Doerrier C, Garcia JA, Escames G, Acuna-Castroviejo D (2012) Treatment with melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12.