Difference between revisions of "Glutamate-aspartate carrier"
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|description=The '''glutamate-aspartate carrier''' catalyzes the electrogenic antiport of glutamate<sup>-</sup> +H<sup>+</sup> for aspartate<sup>-</sup>. It is an important component of the malate-aspartate shuttle in many mitochondria. Due to the symport of glutamate<sup>-</sup> + +H<sup>+</sup>, the glutamate-aspartate antiport is not electroneutal and may be impaired by [[uncoupling]]. [[Aminooxyacetate]] is an [[inhibitor]] of the glutamate-aspartate carrier. | |description=The '''glutamate-aspartate carrier''' catalyzes the electrogenic antiport of glutamate<sup>-</sup> +H<sup>+</sup> for aspartate<sup>-</sup>. It is an important component of the malate-aspartate shuttle in many mitochondria. Due to the symport of glutamate<sup>-</sup> + +H<sup>+</sup>, the glutamate-aspartate antiport is not electroneutal and may be impaired by [[uncoupling]]. [[Aminooxyacetate]] is an [[inhibitor]] of the glutamate-aspartate carrier. | ||
|info=[[ | |info=[[Gnaiger 2012 MitoPathways]] | ||
|type=Substrate ETS | |type=Substrate ETS | ||
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| | |mitopedia topic=Substrate and metabolite | ||
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Latest revision as of 14:54, 25 July 2016
- high-resolution terminology - matching measurements at high-resolution
Glutamate-aspartate carrier
Description
The glutamate-aspartate carrier catalyzes the electrogenic antiport of glutamate- +H+ for aspartate-. It is an important component of the malate-aspartate shuttle in many mitochondria. Due to the symport of glutamate- + +H+, the glutamate-aspartate antiport is not electroneutal and may be impaired by uncoupling. Aminooxyacetate is an inhibitor of the glutamate-aspartate carrier.
Reference: Gnaiger 2012 MitoPathways
MitoPedia topics: Substrate and metabolite
