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Difference between revisions of "HU Budapest Tretter L"

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{{MiPNetLab
{{O2k-Network Lab
|institution=Department of Medical Biochemistry
|institution=Department of Medical Biochemistry


Semmelweis University
Semmelweis University
'''Oroboros O2k-Training Centre'''
'''Power-O2k Network Cluster''': [[HU Budapest Semmelweis Univ]]
|address=37-47. Tuzolto Str.
|address=37-47. Tuzolto Str.
|area code=HU-1088
|area code=HU-1088
Line 9: Line 13:
|weblink=[http://www.biokemia.sote.hu Medical Biochemistry]
|weblink=[http://www.biokemia.sote.hu Medical Biochemistry]
|Contact=Tretter Laszlo
|Contact=Tretter Laszlo
|MiPNetLab=Horvath Gergoe, Komlodi Timea, Nagy Adam
 
|Team previous=Kiss Gergely, Konrad Csaba, Szarvas Nikolett
|MiPNetLab=
|Status=[http://www.oroboros.at/?Power-O2k '''2 Power-O2k'''] 2008-
|Team previous=Horvath Gergoe, Kiss Gergely, Komlodi Timea, Konrad Csaba, Nagy Adam, Szarvas Nikolett
|info=[[MiP2013]], [http://oroboros.at/?IOC66 IOC66], [[IOC62]]
|Status=[[Power-O2k|''' 2 Power-O2k''']] '''O2k-Training Centre''', 2008-
|info=[[IOC132]], [[IOC127]], [[MitoFit Workshop ATP 2017 Innsbruck AT| MitoFit Workshop ATP 2017]], [[MiP2017/MitoEAGLE Hradec Kralove CZ|MitoEAGLE 2017 CZ]], [[IOC124]], [[IOC116]], [[MiPschool Obergurgl 2017| MiPschool 2017]], [[MitoEAGLE Barcelona 2017| MitoEAGLE 2017 ES]],  [[MiP2014]], [[MiPNet18.08_MiP2013|MiP2013 ]], [[IOC75]], [[IOC72]], [[IOC66]], [[IOC62]]
|keyword=Hydrogen peroxide, Synaptosomes, Guinea pigs, Mitochondrion, Reactive oxygen species, Oxidative stress
|keyword=Hydrogen peroxide, Synaptosomes, Guinea pigs, Mitochondrion, Reactive oxygen species, Oxidative stress
}}
}}
== Power-O2k ==
* [[HU Budapest Semmelweis Univ]]
== Cooperation ==
== Cooperation ==


* [[Horvath G|Horvàth Gergö]]: Erasmus scholarship with cooperation at [[MitoCom]] (Oct 2012 to Jan 2013).
* [[Horvath G|Horvàth Gergö]]: Erasmus scholarship with cooperation at [[MitoCom_O2k-Fluorometer|MitoCom]] (Oct 2012 to Jan 2013).


Cooperation Semmelweis University Budapest and Medical University of Innsbruck (Nov 2010 and May 2011).
Cooperation Semmelweis University Budapest and Medical University of Innsbruck (Nov 2010 and May 2011).


*  [[Tretter L]]: Guest lecturer at [http://www.oroboros.at/?IOC66 IOC66 O2k-Fluorometry Workshop].
*  [[Tretter L]]: Guest lecturer at [http://www.oroboros.at/?IOC66 IOC66 O2k-Fluorometry Workshop].
== Feedback ==
* ''First of all I would like to write that O2K works very well in our lab as well.'' - '''[[Tretter Laszlo|Laszlo Tretter]]''' (2009)
== Visiting scientist in the Oroboros O2k-Laboratory ==
:::: [[Image:O2k-Network.png|left|40px|link=O2k-Network|O2k-Network]]
:[[Komlodi Timea|  Timea KomlĂČdi ]]: Visiting scientist at the [[Oroboros Laboratories: visiting scientists |Oroboros O2k-Laboratory]] from November 21 to 28 2016
:[[Horvath Gergo|  Gergö Horvàth]]: Visiting scientist at the [[Oroboros Laboratories: visiting scientists |Oroboros O2k-Laboratory]] from October 2012 to January 2013
[[Category:Power-O2k]]

Revision as of 03:14, 19 November 2019

                



HU Budapest Tretter L

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Department of Medical Biochemistry

Semmelweis University

Oroboros O2k-Training Centre

Power-O2k Network Cluster: HU Budapest Semmelweis Univ

Address 37-47. Tuzolto Str., HU-1088
City Budapest
State/Prov
Country Hungary
Weblink Medical Biochemistry
Contact Tretter Laszlo
Team
Team previous Horvath Gergoe, Kiss Gergely, Komlodi Timea, Konrad Csaba, Nagy Adam, Szarvas Nikolett
Status 2 Power-O2k O2k-Training Centre, 2008-
Oroboros Events IOC132, IOC127, MitoFit Workshop ATP 2017, MitoEAGLE 2017 CZ, IOC124, IOC116, MiPschool 2017, MitoEAGLE 2017 ES, MiP2014, MiP2013 , IOC75, IOC72, IOC66, IOC62
Topics Hydrogen peroxide, Synaptosomes, Guinea pigs, Mitochondrion, Reactive oxygen species, Oxidative stress


O2k-Publications

 PublishedReference
Ravasz 2024 Sci Rep2024Ravasz D, Bui D, Nazarian S, Pallag G, Karnok N, Roberts J, Marzullo BP, Tennant DA, Greenwood B, Kitayev A, Hill C, KomlĂłdi T, Doerrier C, Cunatova K, Fernandez-Vizarra E, Gnaiger E, Kiebish Michael A, Raska A, Kolev K, Czumbel B, Narain NR, Seyfried TN, Chinopoulos C (2024) Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia. Sci Rep 14:1729. https://doi.org/10.1038/s41598-024-51365-4
Donnelly 2023 MitoFit2023Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Compagnion AC, Matera A, Tavernari D, Zanou N, Kayser B, Gnaiger E, Place N (2023) Functional hypoxia reduces mitochondrial calcium uptake. MitoFit Preprints 2023.2. https://doi.org/10.26124/mitofit:2023-0002 — 2024-11-17 published in Redox Biol.
Donnelly 2022 MitoFit Hypoxia2022Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. https://doi.org/10.26124/mitofit:2022-0025.v2 — 2022-11-14 published in Bioenerg Commun 2022.12.
Daradics 2022 PLoS One2022Daradics N, Horvath G, Tretter L, Paal A, Fulop A, Budai A, Szijarto A (2022) The effect of Cyclophilin D depletion on liver regeneration following associating liver partition and portal vein ligation for staged hepatectomy. https://doi.org/10.1371/journal.pone.0271606
Komlodi 2022 BEC2022Komlódi T, Tretter L (2022) The protonmotive force – not merely membrane potential. Bioenerg Commun 2022.16. https://doi.org/10.26124/bec:2022-0016
Horvath 2022 Antioxidants (Basel)2022Horvåth G, Svåb G, Komlódi T, Ravasz D, Kacsó G, Doczi J, Chinopoulos C, Ambrus A, Tretter L (2022) Reverse and forward electron flow-induced H2O2 formation is decreased in α-ketoglutarate dehydrogenase (α-KGDH) subunit (E2 or E3) heterozygote knock out animals. https://doi.org/10.3390/antiox11081487
Mikulas 2020 Materials2020Mikulås K, Komlódi T, Földes A, Svåb G, Horvåth G, Nagy AM, Ambrus A, Gyulai-Gaål Sz, Gera I, Hermann P, Varga G, Tretter L (2020) Bioenergetic Impairment of triethylene glycol dimethacrylate- (TEGDMA-) treated dental pulp stem cells (DPSCs) and isolated brain mitochondria are amended by redox compound methylene blue. Materials (Basel) 13(16):3472.
Svab 2019 Neurochem Res2019Svab G, Doczi J, Gerencser AA, Ambrus A, Gallyas F, SĂŒmegi B, Tretter L (2019) The mitochondrial targets of neuroprotective drug vinpocetine on primary neuron cultures, brain capillary endothelial cells, synaptosomes, and brain mitochondria. Neurochem Res 44:2435-47.
MiPNet23.07 IOC132 Budapest HU2018-08-24
O2k-Network
Budapest HU, 2018 Aug 24-25 Oroboros satellite O2k-Workshop on high-resolution respirometry (HRR), IOC.
Mikulas 2018 Dent Mater2018MikulĂĄs K, Hermann P, Gera I, KomlĂłdi T, HorvĂĄth G, Ambrus A, Tretter L (2018) Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I. Dent Mater 34:e166-e181.
Komlodi 2018 J Bioenerg Biomembr2018KomlĂłdi T, Geibl FF, Sassani M, Ambrus A, Tretter L (2018) Membrane potential and delta pH dependency of reverse electron transport-associated hydrogen peroxide production in brain and heart mitochondria. J Bioenerg Biomembr 50:355-365
Budai 2018 Br J Surg2018Budai A, HorvĂĄth G, Tretter L, RadĂĄk Z, Koltai E, Bori Z, Torma F, LukĂĄts Á, Röhlich P, SzijĂĄrtĂł A, FĂŒlöp A (2018) Mitochondrial function after associating liver partition and portal vein ligation for staged hepatectomy in an experimental model. Br J Surg 106:120-31.
Fischer 2018 BMC Musculoskelet Disord2018Fischer MJ, Horvath G, Krismer M, Gnaiger E, Goebel G, Pesta DH (2018) Evaluation of mitochondrial function in chronic myofascial trigger points - a prospective cohort pilot study using high-resolution respirometry. BMC Musculoskelet Disord 19:388.
Komlodi 2017 Neuropharmacology2017KomlĂłdi T, Tretter L (2017) Methylene blue stimulates substrate-level phosphorylation catalysed by succinyl-CoA ligase in the citric acid cycle. Neuropharmacology 123:287-98.
Stepanova 2017 J Cereb Blood Flow Metab2017Stepanova A, Kahl A, Konrad C, Ten V, Starkov AS, Galkin A (2017) Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia-reperfusion injury. J Cereb Blood Flow Metab 37:3649-58.
Nemeth 2016 FASEB J2016Németh B, Doczi J, Csete D, Kacso G, Ravasz D, Adams D, Kiss G, Nagy AM, Horvath G, Tretter L, Mócsai A, Csépånyi-Kömi R, Iordanov I, Adam-Vizi V, Chinopoulos C (2016) Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. FASEB J 30:286-300.
Yavari 2016 Cell Metab2016Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martinez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Toth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H (2016) Chronic activation of Îł2 AMPK induces obesity and reduces ÎČ cell function. Cell Metab 23:821-36.
Koncsos 2016 Am J Physiol Heart Circ Physiol2016Koncsos G, Varga ZV, Baranyai T, Boengler K, Rohrbach S, Li L, SchlĂŒter KD, Schreckenberg R, Radovits T, OlĂĄh A, MĂĄtyĂĄs C, Lux Á, Al-Khrasani M, KomlĂłdi T, Bukosza N, MĂĄthĂ© D, Deres L, BartekovĂĄ M, RajtĂ­k T, AdameovĂĄ A, Szigeti K, Hamar P, Helyes Z, Tretter L, Pacher P, Merkely B, Giricz Z, Schulz R, Ferdinandy P (2016) Diastolic dysfunction in prediabetic male rats: role of mitochondrial oxidative stress. Am J Physiol Heart Circ Physiol 311:H927-43.
Kiss 2014 FASEB J2014Kiss G, Konrad C, Pour-Ghaz I, Mansour JJ, NĂ©meth B, Starkov AA, Adam-Vizi V, Chinopoulos C (2014) Diaphorases provide NAD+ in anoxia. FASEB J 28:1682-97.
Tretter 2014 Free Radic Biol Med2014Tretter L, Horvath G, Hölgyesi A, Essek F, Adam-Vizi V (2014) Enhanced hydrogen peroxide generation accompanies the beneficial bioenergetic effects of methylene blue in isolated brain mitochondria. Free Radic Biol Med 77:317-30.
Tretter 2012 Free Radic Biol Med2012Tretter Laszlo, Adam-Vizi Vera (2012) High Ca2+ load promotes hydrogen peroxide generation via activation of α-glycerophosphate dehydrogenase in brain mitochondria. Free Radic Biol Med 53:2119-30.
Komary 2010 Biochim Biophys Acta2010Komary Z, Tretter L, Adam-Vizi V (2010) Membrane potential-related effect of calcium on reactive oxygen species generation in isolated brain mitochondria. Biochim Biophys Acta 1797:922-8.

O2k-Abstracts

 PublishedReference
Komlodi 2023 EUROMIT2023 Bologna2023KomlĂłdi T, Silva FSG, Duarte AI, Mena D, Garcia-Souza LF, Makrecka-Kuka M, Bento G, Grilo LF, Oliveira PJ, Gnaiger E (2023) Off-target effects of etomoxir: inhibition of mitochondrial Complex I and fatty acid oxidation. EUROMIT2023 International Conference on Mitochondrial Pathology.
Donnelly 2022 Abstract Bioblast20222.1. «10+5»
Donnelly Chris
Donnelly Chris, Schmitt S, Cecatto C, Cardoso L, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint« »Watch the presentation«
Komlodi 2022 Abstract Bioblast20223.1. «10+5»
Komlodi Timea
Komlódi Timea, Tretter L (2022) The protonmotive force – not merely membrane potential. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint« »Watch the presentation«
Komlodi 2017 Abstract MITOEAGLE Barcelona2017
COST Action MitoEAGLE
Succinate dehydrogenase regulation via oxaloacetate in brain mitochondria.
Komlodi 2016 Abstract IOC1162016Komlodi T, Geibl F, Sassani M, Adam-Vizi V, Tretter L (2016) The effect of Διmt and ΔpH on mitochondrial reactive oxygen species production - A comparative study using mitochondria isolated from different mammalian tissues. Mitochondr Physiol Network 21.11
Doerrier 2015 Abstract MiPschool Greenville 20152015"Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.
Doerrier 2015 Abstract MiP20152015Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.
Tretter 2014 Abstract MiP20142014Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia.
Meszaros 2014 Abstract MiP20142014Methodological aspects of assessing mitochondrial function in small intestinal mucosal samples of rats and guinea pigs.
Komlodi 2014 Abstract MiP20142014Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation.
Nagy 2014 Abstract MiP20142014Investigation of the energy metabolism of microglial cells.
Tretter 2013 Abstract MiP20132013Tretter L, Komlódi T, Ádåm-Vizi V (2013) The effects of methylmalonic acid on alpha-ketoglutarate supported oxidation in isolated brain, heart and liver mitochondria. Mitochondr Physiol Network 18.08.
Horvath 2012 Abstract Bioblast2012Horvath G, Eigentler A, Gnaiger E, Tretter L (2012) Respiratory substrate effects on mitochondrial membrane potential - experiments with mouse cardiac muscle homogenate. Mitochondr Physiol Network 17.12.
Fasching 2011 Abstract Berlin2011Fasching M, Harrison DK, Tretter L, Gnaiger E (2011) Combination of high-resolution respirometry and fluorometry for continuous monitoring of hydrogen peroxide production by mitochondria with resolution in the nanomolar range. Abstract Berlin.

Cooperation

Cooperation Semmelweis University Budapest and Medical University of Innsbruck (Nov 2010 and May 2011).

Feedback

  • First of all I would like to write that O2K works very well in our lab as well. - Laszlo Tretter (2009)


Visiting scientist in the Oroboros O2k-Laboratory

O2k-Network
Timea KomlĂČdi : Visiting scientist at the Oroboros O2k-Laboratory from November 21 to 28 2016
Gergö Horvàth: Visiting scientist at the Oroboros O2k-Laboratory from October 2012 to January 2013