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Difference between revisions of "Mitochondrial membrane potential"

From Bioblast
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{{MitoPedia
{{MitoPedia
|abbr=mtMP, Δ''ψ''<sub>mt</sub>
|abbr=mtMP, Δ''ψ''<sub>mt</sub>
|description=The '''mitochondrial membrane potential''', mtMP, is the electric part of the protonmotive force, Δ''p''<sub>mt</sub>.
|description=
The '''mitochondrial membrane potential''', mtMP, is the electric part of the protonmotive force, Δ''p''<sub>mt</sub>.


:: Δ''ψ''<sub>mt</sub> = Δ''p''<sub>mt</sub> - Δ''µ''<sub>H+</sub> / ''F''
Δ''ψ''<sub>mt</sub> = Δ''p''<sub>mt</sub> - Δ''µ''<sub>H+</sub> / ''F''


mtMP or Δ''ψ''<sub>mt</sub> is the potential difference across the inner mitochondrial (mt) membrane, expressed in the electric unit of volt [V]. Electric force of the mitochondrial membrane potential is the electric energy change per ‘motive’ electron or per electron moved across the transmembrane potential difference, with the number of ‘motive’ electrons expressed in the unit coulomb [C].
mtMP or Δ''ψ''<sub>mt</sub> is the potential difference across the inner mitochondrial (mt) membrane, expressed in the electric unit of volt [V]. Electric force of the mitochondrial membrane potential is the electric energy change per ‘motive’ electron or per electron moved across the transmembrane potential difference, with the number of ‘motive’ electrons expressed in the unit coulomb [C].
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The chemical part of the protonmotive force, ''µ''<sub>H+</sub> / ''F'' stems from the difference of pH across the mt-membrane. It contains a factor that bridges the gap between the electric force [J/C] and the chemical force [J/mol]. This factor is the Faraday constant, ''F'', for conversion between electric force expressed in joules per coulomb or Volt [V=J/C] and chemical force with the unit joules per mole or Jol [Jol=J/mol],
The chemical part of the protonmotive force, ''µ''<sub>H+</sub> / ''F'' stems from the difference of pH across the mt-membrane. It contains a factor that bridges the gap between the electric force [J/C] and the chemical force [J/mol]. This factor is the Faraday constant, ''F'', for conversion between electric force expressed in joules per coulomb or Volt [V=J/C] and chemical force with the unit joules per mole or Jol [Jol=J/mol],


:: ''F'' = 96.4853 kJol/V = 96,485.3 C/mol
''F'' = 96.4853 kJol/V = 96,485.3 C/mol
 
|info=[[Mitchell 1961 Nature]], [[Gnaiger 2014 Preface MiP2014]]
|info=[[Mitchell 1961 Nature]], [[Gnaiger 2014 Preface MiP2014]]
}}
}}
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|mitopedia topic=Respiratory state
|mitopedia topic=Respiratory state
}}
}}
:» [[MiPNet15.08 TPP-Electrode]]
:» [[MiPNet15.03 O2k-MultiSensor-ISE]]

Revision as of 19:48, 6 February 2016


high-resolution terminology - matching measurements at high-resolution


Mitochondrial membrane potential

Description

The mitochondrial membrane potential, mtMP, is the electric part of the protonmotive force, Δpmt.

Δψmt = Δpmt - ΔµH+ / F

mtMP or Δψmt is the potential difference across the inner mitochondrial (mt) membrane, expressed in the electric unit of volt [V]. Electric force of the mitochondrial membrane potential is the electric energy change per ‘motive’ electron or per electron moved across the transmembrane potential difference, with the number of ‘motive’ electrons expressed in the unit coulomb [C].

The chemical part of the protonmotive force, µH+ / F stems from the difference of pH across the mt-membrane. It contains a factor that bridges the gap between the electric force [J/C] and the chemical force [J/mol]. This factor is the Faraday constant, F, for conversion between electric force expressed in joules per coulomb or Volt [V=J/C] and chemical force with the unit joules per mole or Jol [Jol=J/mol],

F = 96.4853 kJol/V = 96,485.3 C/mol

Abbreviation: mtMP, Δψmt

Reference: Mitchell 1961 Nature, Gnaiger 2014 Preface MiP2014


MitoPedia methods: Respirometry, Fluorometry 


MitoPedia topics: "Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory state"Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. 

» MiPNet15.03 O2k-MultiSensor-ISE