Oroboros Ecosystem Agenda 2021 Archive
- Mitochondria and Cell Research - the Oroboros Ecosystem
Last week
2021 Week 4
- Jan-25 Mo
- Jan-26 Tu- ÖGMBT Life Science Tuesdays
- Jan-27 We
Cell-permeable succinate prodrug NV118 improves statin-induced mitochondrial dysfunction in human platelets
- from the O2k-Network »RO Timisoara Muntean DM« and »SE Lund Elmer E«
- Avram VF, Chamkha I, Åsander-Frostner E, Ehinger JK, Timar RZ, Hansson MJ, Muntean DM, Elmér E (2021) Cell-permeable succinate rescues mitochondrial respiration in cellular models of statin toxicity. Int J Mol Sci 22:424. »Bioblast link«
- Jan-28 Th
A quote from MitoPathways Chapter 6. Convergent electron transfer at the Q-junction: The concept on convergent electron transfer at the Q-junction (ETS) challenges conventional OXPHOS analysis based on the ETC terminology and a way of thinking about the mitochondrial ‘electron transfer chain’ - »Gnaiger 2020 BEC MitoPathways«.
- Jan-29 Fr
SUIT protocols with Magnesium Green™ (MgG) can be used to study respiration and ATP production P»
MgG dye does not affect respiration of cardiac isolated mitochondria.
- Cardoso LHD, Doerrier C, Gnaiger E (2021) Magnesium Green for fluorometric measurement of ATP production does not interfere with mitochondrial respiration. MitoFit Preprints 2021.1. doi:10.26124/mitofit:2021-0001.
Jan 2021
- Jan-01 Fr
- Happy New Year!
2021 Week 1
- Jan-04 Mo
- The Oroboros office is enjoying a break from December 24th to January 6th.
- Jan-05 Tu
- Jan-06 We
- Jan-07 Th
Oroboros Instruments is pleased to be a collaborator on the CureMILS project that has recently been approved for EJP-RD funding.
Led by O2k-Network member, Alessandro Prigione, the project aims to employ a novel approach to enable drug discovery of Mitochondrial DNA (mtDNA)-associated Leigh syndrome (MILS).
- Read more »CureMILS«
- Jan-08 Fr
Liver mitochondrial adaptation in a mouse model of NAFLD induced by a Western-style diet
- from the O2k-Network »CZ Hradec Kralove Cervinkova Z«
- Staňková P, Kučera O, Peterová E, Lotková H, Maseko TE, Nožičková K, Červinková Z (2020) Adaptation of mitochondrial substrate flux in a mouse model of nonalcoholic fatty liver disease. Int J Mol Sci 21:E1101. »Bioblast link«
2021 Week 2
- Jan-11 Mo
Are you a beginner or need a refresher on using SUIT protocols with DatLab7.4?
- » O2k-Videosupport: How to perform an experiment with a SUIT DL-Protocol« and » Run DL-Protocol/Set O2 limit in DatLab «
- communicated by »Komlodi Timea« and Schmitt Sabine«
- Jan-12 Tu - ÖGMBT Life Science Tuesdays
- Jan-13 We
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Positive effect of regular physical activity on mitochondrial respiration in burnout syndrome
- from the O2k-Network »CH Basel Eckert A«
- Brand S, Ebner K, Mikoteit T, Lejri I, Gerber M, Beck J, Holsboer-Trachsler E, Eckert A (2020) Influence of regular physical activity on mitochondrial activity and symptoms of burnout-an interventional pilot study. J Clin Med 9:E667.»Bioblast link«
- Jan-14 Th
- Jan-15 Fr
2021 Week 3
- Jan-18 Mo
- Jan-19 Tu
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Complex III is essential in mitochondrial electron transfer system maturation and supercomplex formation
- from the O2k-Network »US FL Miami Moraes CT«
- Protasoni M, Pérez-Pérez R, Lobo-Jarne T, Harbour ME, Ding S, Peñas A, Diaz F, Moraes CT, Fearnley IM, Zeviani M, Ugalde C, Fernández-Vizarra E (2020) Respiratory supercomplexes act as a platform for complex III-mediated maturation of human mitochondrial complexes I and IV. EMBO J 39:e102817. »Bioblast link«
- Jan-20 We
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A quote from MitoPathways Chapter 3. Normalization: Respiratory OXPHOS capacity P in human skeletal muscle ranges from 60 to 160 pmol∙s-1∙mg-1 based on wet muscle mass of permeabilized fibers. By comparison, mass-specific electron transfer capacity E is approximately 25 pmol∙s-1∙mg-1 in platelets and senescent fibroblasts and 40 to 80 pmol∙s-1∙mg-1 in PBMC, HEK, CEM, HUVEC, and young fibroblasts. ― Are these values comparable? - »Gnaiger 2020 BEC MitoPathways«.
- Jan-21 Th
Measuring ATP production with Magnesium Green – which sample preparations work?
Magnesium Green (MgG) can be used with mitochondrial preparations: isolated mitochondria, tissue homogenates, and permeabilized cells and tissues.
- »MgG« and »Publications MgG«
- communicated by »Cardoso Luiza« and »Komlodi Timea«
- Jan-22 Fr
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