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Oroboros Ecosystem Agenda 2022 Archive

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Oroboros Ecosystem Agenda 2022 Archive

Mitochondria and Cell Research - the Oroboros Ecosystem
» Current Oroboros Ecosystem Agenda

Last week

2022 Week 46
  • Nov- 14 Mo - World Diabetes Day
O2k-brief repository Mistimed eating, e.g., during shift-work, disrupts mitochondrial function and could contribute to type-2 diabetes mellitus
  • de Goede P, Wüst RCI, Schomakers BV, Denis S, Vaz FM, Pras-Raves ML, van Weeghel M, Yi CX, Kalsbeek A, Houtkooper RH (2022) Time-restricted feeding during the inactive phase abolishes the daily rhythm in mitochondrial respiration in rat skeletal muscle. »Bioblast link«
from the O2k-Network »NL Amsterdam Wuest RC«

  • Nov- 15 Tu
O2k-Publications in the MiPMap Again not a Warburg effect - OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation

Reproducibility is a decisive element in the progress of knowledge. The recent study by Zhang et al (2022) fully confirmed the pattern of OXPHOS remodeling described by Schöpf et al (2020) in prostate cancer.

  • Schöpf Bernd, Weissensteiner Hansi, Schäfer Georg, Fazzini Federica, Charoentong Pornpimol, Naschberger Andreas, Rupp Bernhard, Fendt Liane, Bukur Valesca, Giese Irina, Sorn Patrick, Sant’Anna-Silva Ana Carolina, Iglesias-Gonzalez Javier, Sahin Ugur, Kronenberg Florian, Gnaiger Erich, Klocker Helmut (2020) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. »Bioblast link«
  • Zhang A, Gupte AA, Chatterjee S, Li S, Ayala AG, Miles BJ, Hamilton DJ (2022) Enhanced succinate oxidation with mitochondrial Complex II reactive oxygen species generation in human prostate cancer. »Bioblast link«

  • Nov- 16 We
»AussieMit 2022 Sydney AU« Nov 16-18

  • Nov- 17 Th - World Pancreatic Cancer Day



  • Nov- 18 Fr

Nov 2022

2022 Week 44
  • Nov- 01 Tu

  • Nov- 02 We

  • Nov- 03 Th
O2k-Publications in the MiPMap "This tissue [white adipose tissue] shows a persistent mitochondrial dysfunction that compromises tissue metabolic plasticity after obesity"
  • Gonzalez-Franquesa A et al (2022) Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. »Bioblast link«
from the O2k-Network »ES Barcelona Garcia-Roves PM«, »ES Barcelona Claret M« and »DE Cologne Trifunovic A«

  • Nov- 04 Fr

  • Nov-05 Sa
Abstract submission open for EUROMIT2023 Bologna IT

2022 Week 45
  • Nov- 07 Mo

  • Nov- 08 Tu
O2k-brief repository MCT1 plays a role in diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction.
  • Hadjihambi A, Konstantinou C, Klohs J, Monsorno K, Le Guennec A, Donnelly C, Cox J, Kusumbe A, Hosford PS, Soffientini U, Lecca S, Mameli M, Jalan R, Paolicelli RC, Pellerin L (2022) Partial MCT1 invalidation protects against diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction. »Bioblast link«
from the O2k-Network »CH Lausanne Place N«

  • Nov- 09 We
O2k-Publications in the MiPMap "Monitoring the dissipative component of mitochondrial respiration, efficiency of ATP production, and mitochondrial outer membrane damage during the first 6 h of NMP [normothermic machine perfusion] predicts the clinical outcome of the transplantation."
  • Meszaros AT, Hofmann J, Buch ML , Cardini B, Dunzendorfer-Matt T, Nardin F, Blumer MJ, Fodor M, Hermann M, Zelger B, Otarashvili G, Schartner M, Weissenbacher A, Oberhuber R, Resch T, Troppmair J, Öfner D, Zoller H, Tilg H, Gnaiger E, Hautz T, Schneeberger S (2022) Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome. »Bioblast link«
from the O2k-Network »AT Innsbruck Schneeberger S« and »AT Innsbruck Oroboros«

  • Nov- 10 Th
O2k-Publications in the MiPMap "High-altitude of the mountain spa environment improved mitochondrial fitness as could be seen from improved CI-linked OXPHOS and ET capacity of platelet mitochondria of patients with post-COVID-19 syndrome"
  • Gvozdjáková A, Sumbalová Z, Kucharská J, Rausová Z, Kovalčíková E, Takácsová T, Navas P, López-Lluch G, Mojto V, Palacka P (2022) Mountain spa rehabilitation improved health of patients with post-COVID-19 syndrome: pilot study. »Bioblast link«
from the O2k-Network »SK Bratislava Sumbalova Z«

  • Nov- 11 Fr

Oct 2022

 2022 Week 40
  • Oct-03 Mo - Breast Cancer Awareness Month
O2k-Workshops.png 155th Oroboros O2k-Workshop on high-resolution respirometry (HRR) Oct 3-8
  • The Nobel Prize in Physiology or Medicine 2022 was awarded to Svante Pääbo "for his discoveries concerning the genomes of extinct hominins and human evolution" - https://www.nobelprize.org/ - See Neanderthal man.
O2k-brief repository Doxorubicin-transferrin conjugate alters mitochondrial bioenergetics in breast cancer cells
  • Wigner P, Zielinski K, Labieniec-Watala M, Marczak A, Szwed M (2021) Doxorubicin-transferrin conjugate alters mitochondrial homeostasis and energy metabolism in human breast cancer cells. »Bioblast link«
from the O2k-Network »PL Lodz Watala C«

  • Oct-04 Tu
O2k-Workshops.png 155th Oroboros O2k-Workshop on high-resolution respirometry (HRR) Oct 3-8
O2k-Publications in the MiPMap “Exposure to fat feeding during pregnancy can provide metabolic advantages in the offspring, which may explain the results of [mice weaned to regular chow] demonstrating improved mitochondrial respiratory function and efficiency in the presence of fatty acid substrates since the heart relies heavily upon efficient fatty acid oxidation to meet its energy demands.”
  • Chiñas Merlin A, Gonzalez K, Mockler S, Perez Y, Jia UA, Chicco AJ, Ullevig SL, Chung E (2022) Switching to a standard chow diet at weaning improves the effects of maternal and postnatal high-fat and high-sucrose diet on cardiometabolic health in adult male mouse offspring. »Bioblast link«
from the O2k-Network »US CO Fort Collins Chicco AJ«

  • Oct-05 We
O2k-Workshops.png 155th Oroboros O2k-Workshop on high-resolution respirometry (HRR) Oct 3-8
MitoFit pdf “Mitochondrial Ca2+ handling shapes astrocytic function and is key toward brain homeostasis.”
from the O2k-Network »BR Sao Paulo Kowaltowski AJ«

  • Oct-06 Th
O2k-Workshops.png 155th Oroboros O2k-Workshop on high-resolution respirometry (HRR) Oct 3-8

  • Oct-07 Fr
O2k-Workshops.png 155th Oroboros O2k-Workshop on high-resolution respirometry (HRR) Oct 3-8

  • Oct-08 Sa
O2k-Workshops.png 155th Oroboros O2k-Workshop on high-resolution respirometry (HRR) Oct 3-8

  • Oct-01 Sa
Abstract submission deadline for »BPS2023 San Diego US«
2022 Week 41
  • Oct-10 Mo - World Mental Health Day
O2k-Publications in the MiPMap Positive effect of regular physical activity on mitochondrial respiration in burnout syndrome
  • Brand S, Ebner K, Mikoteit T, Lejri I, Gerber M, Beck J, Holsboer-Trachsler E, Eckert A (2020) Influence of regular physical activity on mitochondrial activity and symptoms of burnout-an interventional pilot study. J Clin Med 9:E667.»Bioblast link«
from the O2k-Network »CH Basel Eckert A«

  • Oct-11 Tu

  • Oct-12 We - Breast Cancer Awareness Month
O2k-Publications in the MiPMap "NS-linked OXPHOS and ET capacity [were] decreased after prolonged exposure to BAM15."
  • Zunica ERM, Axelrod CL, Cho E, Spielmann G, Davuluri G, Alexopoulos SJ, Beretta M, Hoehn KL, Dantas WS, Stadler K, King WT, Pergola K, Irving BA, Langohr IM, Yang S, Hoppel CL, Gilmore LA, Kirwan JP (2021) Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15. »Bioblast link«
from the O2k-Network »US LA Baton Rouge Noland RC«, »US LA Baton Rouge Irving BA« and »US OH Cleveland Hoppel CL«

  • Oct-13 Th

  • Oct-14 Fr

  • Oct-15 Sa
Registration open for EUROMIT2023 Bologna IT
2022 Week 42
  • Oct-17 Mo
O2k-Publications in the MiPMap “Chronic nitrate supplementation alone may not be a sufficient stimulus to elicit increases in muscle tissue oxygenation or respiration in [heart failure reduced ejection fraction]”
  • Woessner MN, Neil C, Saner NJ, Goodman CA, McIlvenna LC, Ortiz de Zevallos J, Garnham AP, Levinger I, Allen JD (2020) Effect of inorganic nitrate on exercise capacity, mitochondria respiration and vascular function in heart failure reduced ejection fraction. »Bioblast link«
from the O2k-Network »AU Melbourne Bishop DJ«

  • Oct-18 Tu
MitoPedia
Gnaiger 2020 BEC MitoPathways
BEC tutorial: Find out the straight (yet enigmatic) connection between Gibbs energy G [J] and the 'molar Gibbs energy' of a transformation [J·mol-1], which is better called the Gibbs force:

  • Oct-19 We - Breast Cancer Awareness Month
O2k-Publications in the MiPMap "Moderate aerobic physical exercise reduces TNBC [Triple-negative breast cancer] tumoral growth with effect on tumor metabolism, characterized by a reduction in mitochondrial respiratory capacity"
  • Vulczak A, Souza AO, Ferrari GD, Azzolini AECS, Pereira-da-Silva G, Alberici LC (2020) Moderate exercise modulates tumor metabolism of triple-negative breast cancer. »Bioblast link«
from the O2k-Network »BR Ribeirao Preto Alberici LC«

  • Oct-20 Th
FAT4BRAIN »FAT4BRAIN Symposium Jena DE«  Oct 20-21

  • Oct-21 Fr
MitoPedia
Gnaiger 2020 BEC MitoPathways
BEC tutorial: How intensive is an intensive — in contrast to extensive — quantity?

2022 Week 43
  • Oct-24 Mo
»CRUK Beatson Institute Workshop 2022 Glasgow UK« Oct 24-25

  • Oct-25 Tu- Breast Cancer Awareness Month
O2k-Publications in the MiPMap "mtSrc-dependent reduction of mtDNA levels lead to OXPHOS deficiency and a more aggressive phenotype [of breast cancer]. Inhibitors specific for mtSrc could therefore restore mitochondrial activity in TNBC cells, and ultimately stop malignancy"
  • Djeungoue-Petga MA, Lurette O, Jean S, Hamel-Côté G, Martín-Jiménez R, Bou M, Cannich A, Roy P, Hebert-Chatelain E (2019) Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells. »Bioblast link«
from the O2k-Network »CA Moncton Hebert-Chatelain E«

  • Oct-26 We
»13th Targeting Mitochondria Congress 2022 Berlin DE« Oct 26-28

  • Oct-27 Th

  • Oct-28 Fr
MitoPedia
Gnaiger 2020 BEC MitoPathways
BEC tutorial: Is the thermodynamics of irreversible processes based on an outdated paradigm?

  • Oct-31 Mo- Breast Cancer Awareness Month
O2k-Publications in the MiPMap "Haplogroup D5 [risk factor of breast cancer] exhibited reduced mitochondrial OXPHOS function compared to that of the non-D5 haplogroups […] because of not only lower Complex I activity but also decreased Complex III activity"
  • Ma L, Fu Q, Xu B, Zhou H, Gao J, Shao X, Xiong J, Gu Q, Wen S, Li F, Shen L, Chen G, Fang H, Lyu J (2017) Breast cancer-associated mitochondrial DNA haplogroup promotes neoplastic growth via ROS-mediated AKT activation. »Bioblast link«

Sep 2022

  • Sep- 01 Th - Leukemia and Lymphoma Awareness Month
O2k-Publications in the MiPMap Metformin-mediated reduction of mitochondrial activity contributes to decreased cell viability in myeloproliferative neoplasms cells
  • Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F (2018) Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. Cell Death Dis 9:311. »Bioblast link«
from the O2k-Network »BR Ribeirao Preto Alberici LC«

  • Sep-02 Fr
 2022 Week 36
  • Sep-05 Mo - Prostate Cancer Awareness Month
O2k-Publications in the MiPMap “Mitochondria of the malignant prostate cells have a higher affinity for succinate and this metabolite supports mitochondrial physiology through the induction of expression and activities of mitochondrial complexes”
  • Bastos Sant'Anna Silva AC, Perez-Valencia JA, Sciacovelli M, Lalou C, Sarlak S, Tronci L, Nikitopoulou E, Meszaros AT, Frezza C, Rossignol R, Gnaiger E, Klocker H (2021) Succinate anaplerosis has an onco-driving potential in prostate cancer cells. Cancers 13:1727.»Bioblast link«
from the O2k-Network »AT Innsbruck Oroboros« and »FR Bordeaux Rossignol R«

  • Sep-06 Tu
Oroboros quality management
How does proficiency testing help achieve quality and reproducibility?

Providing a pre-established set of testing criteria improves and standardizes technical performance.

- »Proficiency test«

- communicated by »Baglivo Eleonora« and »Tindle-Solomon Lisa«


  • Sep-07 We

  • Sep-08 Th

  • Sep-09 Fr
 2022 Week 37
  • Sep-12 Mo
MitoFit pdf From the MitoKIN project - preprint to publication:
  • Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Physiological cell culture media tune mitochondrial bioenergetics and drug sensitivity in cancer cell models. https://doi.org/10.3390/cancers14163917
from the O2k-Network »AT Innsbruck Oroboros«

  • Sep-13 Tu

  • Sep-14 We
Posch 2022 BEC
Bioenerg Commun 2022.9:A publication with video presentation from Bioblast 2022: BEC Inaugural Conference

  • Sep-15 Th - World Lymphoma Awareness Day
O2k-Publications in the MiPMap OXPHOS as a potential therapeutic target in classical Hodgkin lymphoma
  • Birkenmeier K, Droese S, Wittig I, Winkelmann R, Käfer V, Doering C, Hartmann S, Wenz T, Reichert AS, Brandt U, Hansmann ML (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. »Bioblast link«
from the O2k-Network »DE Frankfurt Droese S«, »DE Frankfurt Wittig I« and »NL Nijmegen Brandt U«

  • Sep-16 Fr
»Europhysiology 2022 Copenhagen DK« Sep 16-18
 2022 Week 38
  • Sep-19 Mo
MitoGlobal Events World Mitochondrial Disease Week – Sep 18-24

World Mitochondrial Disease Week raises awareness of mitochondrial disease through educational, fundraising and advocacy activities.
See what is happening near you - »https://mitochondrialdiseaseweek.org/events/


  • Sep-20 Tu
Åsander Frostner 2022 BEC Bioenerg Commun 2022.4: A review on the current landscape of mitochondrial disease drug development
  • Åsander Frostner E, Simón Serrano S, Chamkha I, Donnelly E, Elmér E, Hansson MJ (2022) Towards a treatment for mitochondrial disease: current compounds in clinical development. https://doi.org/10.26124/bec:2022-0004
from the O2k-Network »SE Lund Elmer E«

  • Sep-21 We
»The 77th Japanese Society of Physical Fitness and Sports Medicine 2022 Tochigi JP« Sep 21-23
O2k-Publications in the MiPMap "By tracing the carbon flow of the nutrients glucose and glutamine in cells derived from patients with different genetically defined causes of primary mitochondrial diseases (PMD), we identified several key metabolic changes supporting the major importance of an NAD+/NADH imbalance in PMD."
  • Adant I, Bird M, Decru B, Windmolders P, Wallays M, de Witte P, Rymen D, Witters P, Vermeersch P, Cassiman D, Ghesquière B (2022) Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction. »Bioblast link«
from the O2k-Network »BE Leuven Vermeersch P«

  • Sep-22 Th
»BEC tutorial-Living_Communications pmF« Prague, Sep 22
»EMC2022 Prague CZ« Sep 22-26
O2k-brief repository A ketogenic diet is a promising approach towards alleviating mitochondrial dysfunction in MELAS disease.
  • Belal S, Goudenège D, Bocca C, Dumont F, Chao De La Barca JM, Desquiret-Dumas V, Gueguen N, Geffroy G, Benyahia R, Kane S, Khiati S, Bris C, Aranyi T, Stockholm D, Inisan A, Renaud A, Barth M, Simard G, Reynier P, Letournel F, Lenaers G, Bonneau D, Chevrollier A, Procaccio V (2022) Glutamate-induced deregulation of krebs cycle in mitochondrial encephalopathy lactic acidosis syndrome stroke-like episodes (MELAS) syndrome is alleviated by ketone body exposure. »Bioblast link«
from the O2k-Network »FR Angers Gueguen N«

  • Sep-23 Fr
O2k-Publications in the MiPMap Investigating the cause of late-onset SLC25A26-related mitochondrial disease
  • Schober FA, Tang JX, Sergeant K, Moedas MF, Zierz CM, Moore D, Smith C, Lewis D, Guha N, Hopton S, Falkous G, Lam A, Pyle A, Poulton J, Gorman GS, Taylor RW, Freyer C, Wredenberg A (2022) Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease. »Bioblast link«
from the O2k-Network »BE Leuven Vermeersch P«

  • Sep-24 Sa

  • Sep-25 Su
12:10 (GMT+2): Erich Gnaiger presenting at EMC2022 Prague CZ - Body mass excess, muscle mass, obesity and mitochondrial fitness

 2022 Week 39 
  • Sep-26 Mo
»EMC2022 Prague CZ« Sep 22-26

  • Sep-27 Tu
»EMBO-FEBS Lecture Course 2022 Budva ME« Sep 27-Oct 1

  • Sep-28 We
»BMT 2022 Innsbruck AT« Sep 28-30
MitoFit pdf “Calcium-induced [mtPTP] is suppressed by exogenous additions of ADP compared to ADP combined with a hexokinase 2-deoxyglucose system of recycling ATP to ADP.”
  • Bellissimo CA, Sondergaard S, Hughes MC, Ramos SV, Larsen S, Perry CGR (2022) The influence of adenylate cycling on mitochondrial calcium-induced permeability transition pore in permeabilized skeletal muscle fibres. https://doi.org/10.26124/mitofit:2022-0026
from the O2k-Network »CA Toronto Perry CG«, »DK Copenhagen Larsen S«

  • Sep-29 Th - World Heart Day
O2k-brief repository Respiration compromised in brain and heart tissue homogenate after cardiac arrest and ischemia/reperfusion injury
  • Liang L, Zhang G, Cheng C, Li H, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W (2021) High-resolution respirometry for evaluation of mitochondrial function on brain and heart homogenates in a rat model of cardiac arrest and cardiopulmonary resuscitation. -»Bioblast link«
from the O2k-Network »US VA Richmond Mangino MJ« 

  • Sep-30 Fr
»BEC tutorial-Living_Communications pmF« Schröcken, Sep 30 - Oct 2
Abstract submission deadline for »AlgaEurope 2022 Rome IT«
Abstract submission deadline for »AussieMit 2022 Sydney AU«
Abstract submission deadline for »CRUK Beatson Institute Workshop 2022 Glasgow UK«

Aug 2022

 2022 Week 31
  • Aug-01 Mo

O2k-Workshops.png 154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5

O2k-Open SupportInfo: improve O2k-checklist: Get started with an O2k-experiment

The O2k-checklist provides an overview of all essential steps for starting an O2k-experiment.
- » MiPNet20.04_O2k-checklist« 
- » communicated by »Cecatto Cristiane« and »Schmitt Sabine«


  • Aug-02 Tu

O2k-Workshops.png 154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5

MitoPedia: SUIT What are the substrate-uncoupler-inhibitor titration reference protocols?

These protocols provide a common baseline for comparison of mitochondrial respiratory control in a large variety of species, tissues and cell types, mt-preparations and laboratories.
- » SUIT reference protocol«

- communicated by »Cardoso Luiza HD« and »Tindle-Solomon Lisa«


  • Aug-03 We

O2k-Workshops.png 154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5

O2k-Videosupport
O2 flux analysis with DatLab 7.4

Use the O2 analysis template:

-  »O2k-Videosupport: O2 flux analysis with DatLab 7.4«


  • Aug-04 Th

O2k-Workshops.png 154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5

MitoPedia
Why do we perform multiple H2O2 calibrations in the Amplex® UltraRed assay?

The sensitivity to H2O2 of the fluorometric signal changes during the experiment as a function of: (1) experimental time and accumulating UltroxRed (similar to resorufin), (2) changes of the optical properties due to titrations, and (3) the radical scavenging capacity of the sample. Therefore, H2O2 calibrations are performed before and after sample addition, and after selected titration steps.

- »Amplex UltraRed« and  »Komlodi et al BEC 2021.4«


  • Aug-05 Fr

O2k-Workshops.png 154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5

O2k-Videosupport
Watch these videos to get started with the Q-Module

- »O2k-Videosupport:Q-Module«

 2022 Week 32
  • Aug-08 Mo
DatLab icon.jpg
DatLab 7.4 is available to download free of charge for all customers.
Please note support for earlier versions will no longer be possible.
Download here«

  • Aug-09 Tu
Baglivio 2022 BEC
Bioenerg Commun 2022.8: Quality Control
  • Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. https://doi.org/10.26124/bec:2022-0008
from the O2k-Network »AT Innsbruck Oroboros«

  • Aug-10 We

  • Aug-11 Th
O2k-Catalogue.jpg
Oroboros innovation: the Sample Holder protecting susceptible samples from damage by stirring in the O2k-chamber.
Sample Holder Set«

  • Aug-12 Fr
2022 Week 33
  • Aug-15 Mo
MitoPedia
BEC tutorial: Did you know that a cell respiring O2 at 100 amol·s-1·x-1 consumes 60 million O2 molecules per second per cell?
Gnaiger 2020 BEC MitoPathways

InO2 = 100 (amol O2)·s-1·(x cell)-1
INO2 = 60.2·106 (x O2)·s-1·(x cell)-1


  • Aug-16 Tu
MitoFit pdf Exploring photosynthesis and dark respiration in the microalgae Chlamydomonas reinhardtii
  • Went N, Di Marcello M, Gnaiger E (2021) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by High-Resolution PhotoRespirometry. MitoFit Prep 2021.5. doi:10.26124/mitofit:2021-0005

  • Aug-17 We

  • Aug-18 Th

  • Aug-19 Fr

  • Aug-20 Sa
Euregio-Innovationspreis Oroboros Instruments has been selected as a Euregio Innovation Prize 2022 finalist for the PB-Module of the NextGen-O2k.

The regions of Tyrol – South Tyrol – Trentino will award the prize to innovations in the health and life sciences.
We are looking forward to presenting our innovation in front of the jury on August 20 at 14:00 in Alpbach, AT.
- » Euregio-Innovationspreis«

EBEClogo2022.jpg EBEC2022 Aix-en-Provence FR Aug 20-25
 2022 Week 34
  • Aug-22 Mo
EBEClogo2022.jpg EBEC2022 Aix-en-Provence FR Aug 20-25

  • Aug-23 Tu
EBEC2022
Erich Gnaiger presenting at EBEC2022 Aix-en-Provence FR - Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by high-resolution PhotoRespirometry

  • Aug-24 We
EBEC2022 A comparison between H2 and N2 gases on mitochondrial respiration and H2O2 production

Sabine Schmitt poster presentation at EBEC2022

  • Schmitt S, Gnaiger E (2022) Short-term effect of molecular hydrogen on mitochondrial respiration and hydrogen peroxide production in permeabilized HEK 293T cells. EBEC 2022. »Bioblast link«

  • Aug-25 Th
EBEC2022
Push and pull effect on the Q-junction

Luiza HD Cardoso poster presentation at EBEC2022.

  • Cardoso LHD, Donnelly C, Komlodi T, Gnaiger E (2022) Characterizing electron transfer through the mitochondrial Q-junction from fatty acid oxidation and TCA cycle on HEK 293T cells: correlation with respiration. EBEC 2022. »Bioblast link«

  • Aug-26 Fr
 2022 Week 35
  • Aug-29 Mo
NextGen-O2k PhotoBiology
An article and video about the NextGen-O2k PhotoBiology Module, which was nominated for the Tyrolean Innovation Prize, were recently published (in German).

- » Read and watch here «


  • Aug-30 Tu
O2k-Open SupportInfo: improve Keep it running or switch it off – what is best for your O2k?

Switching off the O2k after use increases the lifespan of the OroboPOS and saves energy
- »MiPNet22.11_O2k-FluoRespirometer_manual« and »MiPNet19.03_O2k-cleaning_and_ISS« 
- communicated by »Schmitt Sabine« and »Tindle-Solomon Lisa«


  • Aug-31 We

Jul 2022

2022 Week 27


  • Jul- 04 Mo
Bioenergetics Communications A publication from Bioblast 2022: BEC Inaugural Conference

- Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina AJA (2021) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older adult women. https://doi.org/10.26124/bec:2022-0002


  • Jul- 05 Tu
Bioenergetics Communications A publication from Bioblast 2022: BEC Inaugural Conference

- Abed Rabbo M, Stiban J (2022) NUBPL: a mitochondrial Complex I deficiency disorder. https://doi.org/10.26124/bec:2022-0003


  • Jul- 06 We
Bioenergetics Communications A publication from Bioblast 2022: BEC Inaugural Conference

- Åsander Frostner E, Simón Serrano S, Chamkha I, Donnelly E, Elmér E, Hansson MJ (2022) Towards a treatment for mitochondrial disease: current compounds in clinical development. https://doi.org/10.26124/bec:2022-0004


  • Jul- 07 Th
MitoPedia
Mitochondria and bioblasts: Made history
Take some time for history - it adds to your stories:

- »Mitochondria and bioblasts: Made history« 


  • Jul- 08 Fr
2022 Week 28
  • Jul- 11 Mo
Bioenergetics Communications A publication from Bioblast 2022: BEC Inaugural Conference

- Heichler C, Nagy M, Wolf P (2022) Evaluation of hepatotoxic effects of acetaminophen on HepG2 cells by parallel real-time monitoring in a multi-sensor analysis platform for automated cell-based assays. https://doi.org/10.26124/bec:2022-0006


  • Jul- 12 Tu
O2k-Workshops and Events
Gnaiger 2020 BEC MitoPathways
BEC tutorial: Mitochondrial membrane potential and Peter Mitchell’s protonmotive force: elements of the science of bioenergetics.

» BEC tutorial-Living Communications pmF, Schroecken, Austria; 2022 - Sep 30 to Oct 2 - preceding the Oroboros O2k-Workshop on high-resolution respirometry.
- Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. https://doi.org/10.26124/bec:2020-0002


  • Jul- 13 We
MitoPedia
Graphical abstract
"Assuming a publication charge of € 1200 per article, scientists mentioning mitochondria or photosynthesis pay € 100 000 every day in 2021 for ‘selling’ their output to publishers ― over € 36 Mill per year."
- Gnaiger E (2021) Beyond counting papers – a mission and vision for scientific publication. https://doi.org/10.26124/bec:2021-0005
- »Paywall journalism« 


  • Jul- 14 Th

  • Jul- 15 Fr
MitoFit pdf
Oxia terms.png
New version 2 of a preprint from Bioblast 2022: BEC Inaugural Conference

- Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. https://doi.org/10.26124/mitofit:2022-0025.v2

 2022 Week 29
  • Jul- 18 Mo
MitoPedia
Oroboros quality management
What is research?

- »Research« 


  • Jul- 19 Tu
MitoPedia: SUIT Do you want to find the best SUIT protocol for your research questions?

- Use the SUITbrowser: »SUITbrowser«


  • Jul- 20 We

  • Jul- 21 Th
O2k-Open SupportInfo: improve Planning to measure proton flux or mitochondrial membrane potential with ion-selective electrodes in the O2k?

Learn how to assemble the reference electrodes:
- »O2k-Videosupport: Assembly of the reference electrode«
- communicated by »Cardoso Luiza« and »Schmitt Sabine«


  • Jul- 22 Fr
 2022 Week 30
  • Jul-25 Mo
Oroboros quality management
Do scientists take responsibility for energy saving? - Or does biomedical research merely find excuses?

- »Energy saving in research« — more details: MitoPedia: Oroboros QM


  • Jul-26 Tu
»5th Academic Symposium of Metabolic Biology Branch of Chinese Biophysical Society 2022 Zunyi CN« Jul 26-29

  • Jul-27 We
MitoPedia
MiPconference
Body mass M and mass m - what is the difference? Consult MitoPedia for a comment on body mass versus body weight.

- »Body mass with a link to mitObesity« 


  • Jul-28 Th - World Hepatitis Day
O2k-Publications in the MiPMap Cells expressing hepatitis B protein X showed increased ROUTINE, LEAK and ET capacity compared to control cells.
  • Wang B, Li W, Fang H, Zhou H (2018) Hepatitis B virus infection is not associated with fatty liver disease: Evidence from a cohort study and functional analysis. Mol Med Rep 19:320-26. »Bioblast link«

  • Jul-29 Fr

Jun 2022

 2022 Week 23
  • Jun- 06 Mo
Bioenergetics Communications Scientific journals apply yesterday's concepts in the various formats of references with bewildering abbreviations of journals, volumes, issues, page numbers. We can do today's job much better using the BEC https-format — in line with DORA.

- »References in BEC https-format — in MitoPedia: BEC


  • Jun- 07 Tu

  • Jun- 08 We - World Brain Tumor Day 2021
»ESCI 2022 Bari IT« Jun 8-10
Erich Gnaiger presenting at ESCI 2022 Bari IT - Bioenergetic cluster analysis – diagnostic evaluation of mitochondrial respiratory control in human fibroblasts

  • Jun- 09 Th
O2k-Open SupportInfo: improve Are you a beginner or need a refresher on using SUIT protocols with DatLab7.4?

- »O2k-Videosupport: How to perform an experiment with a SUIT DL-Protocol« and »Run DL-Protocol/Set O2 limit in DatLab« 
- communicated by »Schmitt Sabine«


  • Jun- 10 Fr
»ESCI 2022 Bari IT«
Eleonora Baglivo presenting at ESCI 2022 Bari IT - Quality control of mitochondrial respiration medium in high-resolution respirometry with living and permeabilized cells - poster selected for oral presentation

 2022 Week 24
  • Jun- 13 Mo

  • Jun- 14 Tu - World Blood Donor Day

  • Jun- 15 We
MitoPedia
The central role of the Q-junction in mitochondria

The Q-junction is a point of convergence in the electron transfer system. Electrons flow from different dehydrogenases and respiratory Complexes into the Q-junction and then downstream to Complex III.
- »Q-junction« 
- communicated by »Schmitt Sabine« 


  • Jun- 16 Th

  • Jun- 17 Fr
Bioblast_2022
The final program of Bioblast 2022 at a glance

2022, Jun 29 - 30 *** 8 sessions *** Poster session *** Exhibition *** MiPArt *** Social activities
- »Bioblast_2022 Program overview« 


  • Jun- 18 Sa
Bioenergetics Communications
BEC 2022.1. - The book of abstracts is online

Gnaiger E, Cardoso LHD, Tindle-Solomon L, Cocco P, eds (2022) Bioblast 2022: BEC inaugural conference. https://doi.org/10.26124/bec:2022-0001
- »Bioenerg Commun 2022.1.« 

2022 Week 25
  • Jun- 20 Mo
Bioenergetics Communications
BEC 2022.1. - The book of abstracts is online (2022-06-18)

Gnaiger E, Cardoso LHD, Tindle-Solomon L, Cocco P, eds (2022) Bioblast 2022: BEC inaugural conference. https://doi.org/10.26124/bec:2022-0001
- »Bioenerg Commun 2022.1.« 


  • Jun- 21 Tu
Bioblast_2022
The final program of Bioblast 2022 at a glance

2022, Jun 29 - 30 *** 8 sessions *** Poster session *** Exhibition *** MiPArt *** Social activities
- »Bioblast_2022 Program overview« 


  • Jun- 22 We
Bioenergetics Communications
Co-write a BEC editorial

Join the discussion on Jun 30
- » BEC is the future« 


  • Jun- 23 Th
Timing
10+5 min = 600+300 s or 5 min = 300 s

A maximum of 12 or 5 slides - look at abstracts to come prepared
- »Bioblast_2022 Abstracts of oral presentations« 


  • Jun- 24 Fr
Timing
Posters and exhibition

Speakers: stick to the timeline and join the poster sessions and visit the exhibition
- »Bioblast_2022 Abstracts of poster presentations« 

 2022 Week 26
  • Jun- 27 Mo
Timing
Posters and exhibition

Speakers: stick to the timeline and join the poster sessions and visit the exhibition
- »Bioblast_2022 Abstracts of poster presentations« 


  • Jun- 28 Tu
Timing
10+5 min = 600+300 s or 5 min = 300 s

A maximum of 12 or 5 slides - look at abstracts to come prepared
- »Bioblast_2022 Abstracts of oral presentations« 


  • Jun- 29 We
Bioblast2022 logo.png Bioblast 2022 Jun 29-30

  • Jun- 30 Th
Bioblast2022 logo.png Bioblast 2022 Jun 29-30

  • Jul- 01 Fr
O2k-Workshops.png NextGen-O2k all-in-one demo workshop IOC153 Innsbruck AT Jul 1-2

  • Jul- 02 Sa
O2k-Workshops.png NextGen-O2k all-in-one demo workshop IOC153 Innsbruck AT Jul 1-2

May 2022

 2022 Week 18


  • May- 02 Mo - Lyme Disease Awareness Month
FAT4BRAIN »FAT4BRAIN Workshop IOC151 Innsbruck AT«  May 2-3

  • May- 03 Tu

  • May- 04 We
MitoFit pdf "More systematic profiling of mitochondrial bioenergetic states in the presence and absence of lead molecules or kinase drugs could become an asset for anticipating non-desired off-target drug features."

Torres-Quesada Omar, Strich Sophie, Stefan Eduard (2022) Kinase perturbations redirect mitochondrial function. MitoFit Prep 2022.11. https://doi.org/10.26124/mitofit:2022-0011

from the O2k-Network »AT Innsbruck Oroboros«

  • May- 05 Th

  • May- 06 Fr
 2022 Week 19
  • May- 09 Mo

  • May- 10 Tu

  • May- 11 We

  • May- 12 Th - International Awareness Day for Chronic Immunological and Neurological Diseases
»10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE« May 12-15

  • May- 13 Fr

  • May- 14 Sa
13:15-14:15 (GMT+2): 152nd Oroboros O2k-Workshop: Continuous monitoring of mitochondrial Coenzyme Q redox state integrated in high-resolution respirometry at 10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE
16:30 (GMT+2): Gnaiger Erich presenting at 10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE - The mitochondrial Q-junction and coenzyme Q pools: Continuous monitoring of pull and push control of respiration and redox state of the Q-mimetic CoQ2
Cardoso Luiza HD poster session at at 10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE - Coenzyme Q redox state and respiration in permeabilized HEK 293T cells: coupling and pathway control
 2022 Week 20
  • May- 16 Mo

  • May- 17 Tu
O2k-Open SupportInfo: improve How do you know which digitonin concentration to use for permeabilization of the cell plasma membrane when performing experiments with the O2k?

SUIT-010 was designed to determine the optimum digitonin concentration for permeabilization of the cell plasma membrane without damaging the mitochondrial outer membrane.
- »Optimum Digitonin concentration and SUIT-010«
- communicated by »Schmitt Sabine« and »Cecatto Cristiane«


  • May- 18 We

  • May- 19 Th
MitoFit pdf "Instrumental QC is a cornerstone for experimental reproducibility."
  • Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. MitoFit Preprints 2022.18. https://doi.org/10.26124/mitofit:2022-0018.v2
from the O2k-Network »AT Innsbruck Oroboros«

  • May- 20 Fr
»Long Night of Research 2022 Innsbruck AT«
2022 Week 21
  • May- 23 Mo

  • May- 24 Tu
MitoPedia
Do you know the different ways to adjust oxygen concentration in the Oroboros O2k?

- »Setting the oxygen concentration«


  • May- 25 We
O2k-Open SupportTake care Do you load the correct instrumental background correction according to the actual range of experimental O2 concentrations?

Perform and apply the instrumental background test:
- »O2 background correction in DatLab« and »Instrumental oxygen background«


  • May- 26 Th

  • May- 27 Fr

Apr 2022

 2022 Week 14
  • Apr- 04 Mo - April is Parkinson's Awareness Month
O2k-Publications in the MiPMap "Early stage α-synuclein pathology does not influence mitochondrial respiration in the striatum and amygdala [of mice]"
  • Burtscher J, Copin JC, Sandi C, Lashuel HA (2020) Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the striatum and amygdala. eNeuro 7:ENEURO.0110-20.2020. »Bioblast link«
from the O2k-Network »CH Lausanne Place N« and »CH Lausanne Sandi C«

  • Apr- 05 Tu
»VASCage 2022 Innsbruck AT«

  • Apr- 06 We

  • Apr- 07 Th - World Health Day



  • Apr- 08 Fr
 2022 Week 15
  • Apr- 11 Mo - World Parkinson´s Disease Day
Bioenergetics Communications Reviewing cellular models to decipher the mechanisms of mitochondrial dysfunction in Parkinson's disease
  • Krako Jakovljevic N, Ebanks B, Katyal G, Chakrabarti L, Markovic I, Moisoi N (2021) Mitochondrial homeostasis in cellular models of Parkinson’s disease. Bioenerg Commun 2021.2. https://doi.org/10.26124/bec:2021-0002
from the O2k-Networks »RS Belgrade Lalic NM«, »UK Nottingham Chakrabarti L« and »UK Leicester Moisoi N«

  • Apr- 12 Tu

  • Apr- 13 We

  • Apr- 14 Th
O2k-Open SupportInfo: improve Did you know that you can apply instrumental O2 background test parameters (i.e., intercept and slope) from an existing file in DatLab?

In the DatLab file, you can copy the Instrumental O2 background test parameters directly via the ‘Copy from file’ option in the ‘Slope configuration’ window. For more information, see: - »Copy from file«
- communicated by »Cecatto Cristiane«


  • Apr- 15 Fr
 2022 Week 16
  • Apr- 18 Mo

  • Apr- 19 Tu
MitoFit pdf "The physiological Human Plasma-Like Media alters proliferative behavior, mitochondrial bioenergetic states and kinase drug sensitivity of cancer cells when compared to classic cell culture media."
  • Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Human Plasma-Like Media fine-tune mitochondrial function and alter drug sensitivity in cancer cell lines. MitoFit Preprints 2022.8. https://doi.org/10.26124/mitofit:2022-0008
from the O2k-Network »AT Innsbruck Oroboros«

  • Apr- 20 We

  • Apr- 21 Th

  • Apr- 22 Fr - Earth Day 2022
 2022 Week 17


  • Apr- 25 Mo
MitoFit pdf "Proline catabolism through ProDH generates sufficient CIII and CIV proton pumping, supporting ATP production by F1FO-ATPase even when CI is inhibited"

Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation leading to high electron flow through reduction of ubiquinone supports ATP production by F1FO-ATPase in mitochondria with inhibited Complex I. MitoFit Preprints 2022.1.v3. https://doi.org/10.26124/mitofit:2022-0001.v3

from the O2k-Network »AT Innsbruck Oroboros« and »HU Budapest Chinopoulos C«

  • Apr- 26 Tu

  • Apr- 27 We

  • Apr- 28 Th

  • Apr- 29 Fr

Mar 2022

 2022 Week 9
  • Feb- 28 Mo - Rare disease day
EJP-RD logo.png Oroboros Instruments is pleased to collaborate in the CureMILS project

Led by O2k-Network member, Alessandro Prigione, the project aims to employ a novel approach to enable drug discovery for treatment of Mitochondrial DNA (mtDNA)-associated Leigh syndrome (MILS).

- »CureMILS«

  • Mar- 01 Tu - Multiple Sclerosis Awareness Month
Bioblast2022 logo.png
Presenting data from a pilot study on mitochondria bioenergetics and PTSD, Alexander Karabatsiakis will join us at Bioblast 2022.
Bioblast 2022« , »Karabatsiakis Alexander«

  • Mar- 02 We
Bioblast2022 logo.png
NextGen-O2k key opinion leader Tomas Morosinotto has confirmed his talk on Photosynthetic capacity under oscillating light regimes at Bioblast 2022.
Bioblast 2022« , »Morosinotto Tomas«

  • Mar- 03 Th - World Wildlife Day

  • Mar- 04 Fr
Bioblast2022 logo.png
Luboš Sobotka from Charles University, CZ will present The Crabtree effect and clinical nutrition at Bioblast 2022.
Bioblast 2022« , »Sobotka Lubos«
2022 Week 10
  • Mar- 07 Mo
Bioblast2022 logo.png
Johnny Stiban from Birzeit University, PS will be presenting Barth Syndrome: A Genetic Ailment with a Lipid Component and Bioenergetic Ramifications at Bioblast 2022.
Bioblast 2022« , »Stiban Johnny«

  • Mar- 08 Tu - International Women´s Day



  • Mar- 09 We
Bioblast2022 logo.png
From the Medical University Innsbruck, AT we will have Günter Weiss presenting on the linkage of iron availability to mitochondrial function.
Bioblast 2022« , »Weiss Guenter«

  • Mar- 10 Th - World Kidney Day
O2k-Publications in the MiPMap "AT1 receptors and AT2 receptors are expressed in kidney mitochondria and can directly regulate mitochondrial respiration."
  • Friederich-Persson M, Persson P (2020) Mitochondrial angiotensin II receptors regulate oxygen consumption in kidney mitochondria from healthy and type 1 diabetic rats. Am J Physiol Renal Physiol 318:F683-88. »Bioblast link«
from the O2k-Network »SE Uppsala Liss P«
Bioblast2022 logo.png
Sasanka Chakrabarti has confirmed his Bioblast 2022 presentation on rotenone cytotoxicity on SH-SY5Y cells.
Bioblast 2022« , »Chakrabarti Sasanka«

  • Mar- 11 Fr
Bioblast2022 logo.png
The O2k-Network lab of Stefan Schneeberger at the Medical University Innsbruck, AT will be presenting Pre-transplant mitochondrial respiration as a clinical prognostic marker in liver machine perfusion at Bioblast 2022.
Bioblast 2022« , »AT Innsbruck Schneeberger S«
2022 Week 11
  • Mar- 14 Mo
Bioblast2022 logo.png
TissueModels project partner Markus Keller will present Lipidomics of mitochondrial membranes - methods first at Bioblast 2022.
Bioblast 2022« , »TissueModels«

  • Mar- 15 Tu
O2k-Publications in the MiPMap "MDH2 is a metabolic switch rewiring [electron transfer system] and TCA fuelling"
  • Molinié T, Cougouilles E, David C, Cahoreau E, Portais JC, Mourier A (2022) MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle. Biochim Biophys Acta Bioenerg 1863:148532. »Bioblast link«
from the O2k-Network »FR Bordeaux Mourier A«

  • Mar- 16 We
Dorabadge5.png Bioenergetics Communications has signed the Declaration on Research Assessment DORA. «

  • Mar- 17 Th
Bioblast2022 logo.png
NextGen-O2k key opinion leader Anthony Moore will give a talk on the bioenergetics of alternative oxidases at Bioblast 2022.
Bioblast 2022« , »Moore Anthony L«

  • Mar- 18 Fr
MitoPedia
Paywall journalism is the opposite of Open Access.

Though often defined from the individual reader's perspective, a paywall can also apply to an institution (such as a library) or the author.
- »Paywall journalism« , »Gnaiger (2021) Editorial Bioenerg Commun«

 2022 Week 12
  • Mar- 21 Mo - World Down Syndrome Day
O2k-Publications in the MiPMap "A correlation between the reduced respiratory activity and the morphological alterations in DS-HFF [Down Syndrome human primary lines of foetal fibroblasts] mitochondria indicates that the occurrence of de-structured cristae might partly account for the dysfunctioning oxidative phosphorylation in trisomic samples"
  • Piccoli C, Izzo A, Scrima R, Bonfiglio F, Manco R, Negri R, Quarato G, Cela O, Ripoli M, Prisco M, Gentile F, Calì G, Pinton P, Conti A, Nitsch L, Capitanio N (2013) Chronic pro-oxidative state and mitochondrial dysfunctions are more pronounced in fibroblasts from Down syndrome foeti with congenital heart defects. Hum Mol Genet 22:1218-32. »Bioblast link«
from the O2k-Network »IT Foggia Capitanio N«

  • Mar- 22 Tu
Bioblast2022 logo.png
At Bioblast 2022 Leonid A Sazanov will present Why Complex I - Complex II is complex too.
Bioblast 2022« , »Sazanov Leonid A«

  • Mar- 23 We
Bioblast2022 logo.png
Charles Hoppel will contribute to Bioblast 2022 with his talk on diagnostic monitoring of skeletal mitochondrial metabolism.
Bioblast 2022« , »Hoppel Charles L«

  • Mar- 24 Th - World Tuberculosis Day

  • Mar- 25 Fr
NextGen O2k-FluoRespirometry and Redox
An article about the NextGen-O2k was recently published in six languages on the CORDIS EU website.

- » Read here «

 2022 Week 13
  • Mar- 28 Mo
Bioblast2022 logo.png
At Bioblast 2022, NextGen-O2k key opinion leader Pablo Garcia-Roves will give a talk on methodological issues related CoQ redox state, membrane potential, and high-resolution respirometry in permeabilized muscle fibers.
Bioblast 2022« , »Garcia-Roves Pablo Miguel«

  • Mar- 29 Tu

  • Mar- 30 We
»Mitochondrial Communications Serial Webinar 4 2022 Virtual«  20:00-21:30 (GMT+8)

  • Mar- 31 Th
Bioblast2022 logo.png
Shilpa Iyer has confirmed her contribution Understanding Bioenergetics health index and disease severity in mitochondrial disease fibroblasts to Bioblast 2022.
Bioblast 2022« , »Iyer Shilpa«

  • Apr- 01 Fr - Parkinson´s Awareness Month

Feb 2022

2022 Week 5
  • Jan- 31 Mo

  • Feb- 01 Tu
MitoFit pdf From preprint to journal publication:
  • Vernerova A, Garcia-Souza LF, Soucek O, Kostal M, Rehacek V, Krcmova LK, Gnaiger E, Sobotka O (2021) Mitochondrial respiration of platelets: comparison of isolation methods. Biomedicines 9:1859. doi.org/10.3390/biomedicines9121859
from the O2k-Network »CZ Hradec Kralove Cervinkova Z« and »AT Innsbruck Oroboros«

  • Feb- 02 We

  • Feb- 03 Th

  • Feb- 04 Fr
O2k-brief repository Acute sarcoplasmic reticulum calcium leak increases mitochondrial respiration after simulated sprint interval training
  • Zanou N, Dridi H, Reiken S, Imamura de Lima T, Donnelly C, De Marchi U, Ferrini M, Vidal J, Sittenfeld L, Feige JN, Garcia-Roves PM, Lopez-Mejia IC, Marks AR, Auwerx J, Kayser B, Place N (2021) Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. Nat Commun 12:7219. »Bioblast link«
from the O2k-Network »CH Lausanne Place N« and »ES Barcelona Garcia-Roves PM«
2022 Week 6
  • Feb- 07 Mo
Bioblast2022 logo.png
Save-the-date: Bioblast 2022: BEC Inaugural Conference - Jun 28 - Jul 1
Bioblast 2022: Announcements«



  • Feb- 08 Tu
Bioenerg Commun Now accepting living communications for Bioblast 2022 - BEC Inaugural Issue

More details« 


  • Feb- 09 We
Bioenerg Commun 'The scientific literature is exploding in quantity even as it stands still in literary quality.' - Wells WA (2004) Me write pretty one day: how to write a good scientific paper. J Cell Biol 165:757-8. »Bioblast link«

Sequential editions provide an opportunity to improve quality while preventing explosions on quantity. - Gnaiger (2021) Editorial Bioenerg Commun



  • Feb- 10 Th
O2k-Network
Alterations in molecular and cellular pathways contribute to skeletal muscle-related symptoms in Covid-19
  • Soares MN, Eggelbusch M, Naddaf E, Gerrits KHL, van der Schaaf M, van den Borst B, Wiersinga WJ, van Vugt M, Weijs PJM, Murray AJ, Wüst RCI (2022) Skeletal muscle alterations in patients with acute Covid-19 and post-acute sequelae of Covid-19. J Cachexia Sarcopenia Muscle. »Bioblast link«
from the O2k-Network »NL Amsterdam Wuest RC« and »UK Cambridge Murray AJ« 

Innovationpreis2021 group photo.jpg
© WK Tirol/ Die Fotografen
Oroboros is proud to be one of the top 3 nominees for the Tyrolean Innovation Award for the PhotoBiology-Module.

Following the award ceremony organized by the Tyrolean Chamber of Commerce, state council member Anton Mattle, responsible for economy and industry in Tyrol, accepted our invitation to the opening ceremony of Bioblast 2022.

PB-Module« , »Bioblast 2022«
 2022 Week 7
  • Feb- 14 Mo - Donor Day
Bioblast2022 logo.png
MitoKIN project partners Eduard Stefan and Omar Torres-Quesada will present Profiling of allosteric kinase inhibitors: a new way to unveil metabolic changes by boosting or preventing mitochondrial function at Bioblast 2022.
Bioblast 2022« , »MitoKIN«

  • Feb- 15 Tu - International Childhood Cancer Day
Bioenergetics Communications Another step towards PubMed indexing, the ISSN number for Bioenergetics Communications: 2791-4690
»Submit a manuscript«

  • Feb- 16 We
Bioblast2022 logo.png
Werner Koopman has confirmed his presentation at Bioblast 2022 on mitochondrial targeting using the TPP moiety.
Bioblast 2022« , »Koopman Werner JH«

  • Feb- 17 Th
Tiroler Innovationspreis 2021.jpg Read more about the Tyrolean Innovation Award for which we were a top nominee.
Tiroler Wirtshaft article (German)«

  • Feb- 18 Fr
2022 Week 8
  • Feb- 21 Mo
Bioblast2022 logo.png
The O2k-Network lab of Laszlo Tretter at Semmelweis University in Budapest, HU will be presenting The protonmotive force - not merely membrane potential at Bioblast 2022.
Bioblast 2022« , »HU Budapest Tretter L«

  • Feb- 22 Tu

  • Feb- 23 We
Bioblast2022 logo.png
ALAS project partner Thomas Roach will present Oxidative stress in photosynthesis at Bioblast 2022.
Bioblast 2022« , »ALAS«

  • Feb- 24 Th
Bioblast2022 logo.png
Industry partner Incyton will be at Bioblast 2022 with a talk on Long-term monitoring of respiration and morphology of cultured cells.
Bioblast 2022« , »Incyton«

  • Feb- 25 Fr
FAT4BRAIN »FAT4BRAIN 3rd Online ESR Workshop« 

Jan 2022

2022 Week 1
  • Jan- 03 Mo

  • Jan- 04 Tu
O2k-Open SupportInfo: improve Do you know which graph layout to choose in DatLab?

Different layouts are required depending on which instrumental quality control or measurement with biological sample is performed. Learn more about Standard layouts provided in DatLab:
- »Layout for DatLab graphs« 
- communicated by »Schmitt Sabine« and »Komlodi Timea«


  • Jan- 05 We

  • Jan- 06 Th

  • Jan- 07 Fr
Oxia
Oxia: O2 regime controller for HyperOxia to HypOxia in the O2k

- » Learn more here «

2022 Week 2
  • Jan- 10 Mo
Dorabadge5.png Oroboros Instruments supports Bioenergetics Communications.

- » We have signed the Declaration on Research Assessment DORA. «


  • Jan- 11 Tu

  • Jan- 12 We

  • Jan- 13 Th

  • Jan- 14 Fr
2022 Week 3
  • Jan- 17 Mo
Bioenerg Commun 'Assuming a publication charge of € 1200 per article, scientists mentioning mitochondria or photosynthesis pay € 100 000 every day in 2021 for ‘selling’ their output to publishers ― over € 36 Mill per year. ' - Gnaiger (2021) Editorial Bioenerg Commun

  • Jan- 18 Tu
O2k-Publications in the MiPMap The process of Lewy body formation in Parkinson's Disease induces mitochondrial deficits
  • Mahul-Mellier AL, Burtscher J, Maharjan N, Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW, Lashuel HA (2020) The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proc Natl Acad Sci U S A 117:4971-82. Mahul-Mellier 2020 Proc Natl Acad Sci U S A
from the O2k-Network »CH Lausanne Place N«

  • Jan- 19 We
Bioenerg Commun Elsevier bought Pergamon Press in 1991 for £440m (£919m today) from Robert Maxwell. R Maxwell may be known in relation to financial scandals and to his daughter Ghislaine Maxwell who was convicted on 2021-12-29 linked to several federal crimes including her involvement in a sex-trafficking ring with Jeffrey Epstein, to who's former friends belonged British Prince Andrew, former Prime Minister Tony Blair, or ex-US-presidents Bill Clinton and Donald Trump. Due to paywall journals, Open Access in science remains an unfulfilled dream. - Gnaiger (2021) Editorial BEC Living Communication (2022-01-04)

  • Jan- 20 Th
NextGen O2k-FluoRespirometry and Redox
The Q-Module of the NextGen O2k enables electrochemical monitoring of the redox state of the ETS-reactive coenzyme Q pool.

- » Learn more here «


  • Jan- 21 Fr
Bioenerg Commun 'The burden of responsibilities for an urgent change of the academic publishing ecosystem and scientific communication culture must be shared between the shoulders of individual scientists, the backbone of scientific institutions, and the neurology of governmental regulations and funding agencies.' - Gnaiger (2021) Editorial Bioenerg Commun
2022 Week 4
  • Jan- 24 Mo
BEC 2021.3 Oroboros Instruments presents the NextGen-O2k Q-Module at the Q10 Conference:
»10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE« May 12-15
- Poster deadline has been extended to the 6th of February



  • Jan- 25 Tu
MitoFit pdf From preprint to journal publication:
  • Fischer C, Volani C, Komlódi T, Seifert M, Demetz E, Valente de Souza L, Auer K, Petzer V, von Raffay L, Moser P, Gnaiger E, Weiss G (2021) Dietary iron overload and Hfe-/- related hemochromatosis alter hepatic mitochondrial function. Antioxidants 10:1818. doi.org/10.3390/antiox10111818
from the O2k-Network »AT Innsbruck Oroboros«

  • Jan- 26 We
NextGen O2k-FluoRespirometry and Redox
Measure photosynthesis and light enhanced dark respiration with the PB-Module of the NextGen O2k.

- » Learn more here «


  • Jan- 27 Th

  • Jan- 28 Fr
Bioblast Oroboros Ecosystem Agenda and Bioblast alert consider to refrain from propagating scientific publications in paywall and predatory journals. A definition is required of paywall and predatory journals. Paywall and predatory journals are not the future of scientific communication.

Stay alert

Collections from Bioblast agenda

Bioblast alert 2022 Bioblast alert 2022

MitoPedia alert MitoPedia alert
O2k-Publications alert O2k-Publications alert
O2k-Open Support alert O2k-Open Support alert
Oroboros news Oroboros alert