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Difference between revisions of "Oxaloacetate"

From Bioblast
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|abbr=Oa
|abbr=Oa
|description=[[File:Oxaloacetic_acid.jpg|left|100px|Oxaloacetic acid]]
|description=[[File:Oxaloacetic_acid.jpg|left|100px|Oxaloacetic acid]]
'''Oxaloacetic acid''', C<sub>4</sub>H<sub>4</sub>O<sub>5</sub>, occurs under physiological conditions as the anion '''oxaloacetate<sup>2-</sup>, Oa'''. Oxaloacetate is formed from malate by [[Malate dehydrogenase|MDH]]. Oa reacts with [[acetyl-CoA]] through [[citrate synthase]] to form [[citrate]], or with [[glutamate]] through [[transaminase]] to form [[oxoglutarate]] and [[aspartate]]. Oa transport is restricted across the inner [[mitochondrial|mt]]-membrane of various tissues. Oa is a potent inhibitor of [[succinate dehydrogenase]]. Β 
'''Oxaloacetic acid''', C<sub>4</sub>H<sub>4</sub>O<sub>5</sub>, occurs under physiological conditions as the anion '''oxaloacetate<sup>2-</sup>, Oa'''. Oxaloacetate is formed from malate by [[Malate dehydrogenase|MDH]]. Oa reacts with [[acetyl-CoA]] through [[citrate synthase]] to form [[citrate]], or with [[glutamate]] through [[transaminase]] to form [[oxoglutarate]] and [[aspartate]]. Oa transport is restricted across the inner [[mitochondrial|mt]]-membrane of various tissues. Oa is a potent inhibitor of [[succinate dehydrogenase]].
|info=[[Gnaiger 2014 MitoPathways]]
|info=[[Gnaiger 2014 MitoPathways]]
|type=Enzyme
|type=Enzyme
}}
{{MitoPedia concepts|type=Enzyme
}}
}}
{{MitoPedia methods|type=Enzyme
{{MitoPedia methods|type=Enzyme
}}
{{MitoPedia O2k and high-resolution respirometry|type=Enzyme
}}
}}
{{MitoPedia topics
{{MitoPedia topics
|mitopedia topic=Substrate and metabolite
|mitopedia topic=Substrate and metabolite
|type=Enzyme
}}
{{Labeling
|discipline=Mitochondrial Physiology
|enzymes=TCA Cycle and Matrix Dehydrogenases
|topics=Substrate; Glucose; TCA Cycle
|type=Enzyme
|type=Enzyme
}}
}}

Revision as of 09:13, 17 May 2016


high-resolution terminology - matching measurements at high-resolution


Oxaloacetate

Description

Oxaloacetic acid

Oxaloacetic acid, C4H4O5, occurs under physiological conditions as the anion oxaloacetate2-, Oa. Oxaloacetate is formed from malate by MDH. Oa reacts with acetyl-CoA through citrate synthase to form citrate, or with glutamate through transaminase to form oxoglutarate and aspartate. Oa transport is restricted across the inner mt-membrane of various tissues. Oa is a potent inhibitor of succinate dehydrogenase.

Abbreviation: Oa

Reference: Gnaiger 2014 MitoPathways






MitoPedia topics: Substrate and metabolite