Difference between revisions of "Oxaloacetate"
From Bioblast
| (5 intermediate revisions by 3 users not shown) | |||
| Line 1: | Line 1: | ||
{{MitoPedia | {{MitoPedia | ||
|description=''' | |abbr=Oa | ||
|info=[ | |description=[[File:Oxaloacetic_acid.jpg|left|100px|Oxaloacetic acid]] | ||
'''Oxaloacetic acid''', C<sub>4</sub>H<sub>4</sub>O<sub>5</sub>, occurs under physiological conditions as the anion '''oxaloacetate<sup>2-</sup>, Oa'''. Oxaloacetate is formed from malate by [[Malate dehydrogenase|MDH]]. Oa reacts with acetyl-CoA through [[citrate synthase]] to form citrate, or with [[glutamate]] through transaminase to form [[oxoglutarate]] and aspartate. Oa transport is restricted across the inner [[mitochondrial|mt]]-membrane of various tissues. Oa is a potent inhibitor of [[succinate dehydrogenase]]. | |||
|info=[[Gnaiger 2020 BEC MitoPathways]] | |||
}} | }} | ||
{{MitoPedia topics | {{MitoPedia topics | ||
|mitopedia topic=Substrate and metabolite | |mitopedia topic=Substrate and metabolite | ||
}} | }} | ||
Latest revision as of 19:31, 1 January 2021
- high-resolution terminology - matching measurements at high-resolution
Oxaloacetate
Description
Oxaloacetic acid, C4H4O5, occurs under physiological conditions as the anion oxaloacetate2-, Oa. Oxaloacetate is formed from malate by MDH. Oa reacts with acetyl-CoA through citrate synthase to form citrate, or with glutamate through transaminase to form oxoglutarate and aspartate. Oa transport is restricted across the inner mt-membrane of various tissues. Oa is a potent inhibitor of succinate dehydrogenase.
Abbreviation: Oa
Reference: Gnaiger 2020 BEC MitoPathways
MitoPedia topics:
Substrate and metabolite
