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Difference between revisions of "PBMC"

From Bioblast
(Created page with "{{MitoPedia |abbr=PBMC |description='''Peripheral blood mononuclear cell''' (PBMC) is a fraction of the leucocyte population in the blood composed by cells with round nucleus....")
 
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|abbr=PBMC
|abbr=PBMC
|description='''Peripheral blood mononuclear cell''' (PBMC) is a fraction of the leucocyte population in the blood composed by cells with round nucleus. PBMC consist of lymphocytes (T, B and NK cells) and monocytes. During extraction, neutrophils and platelets can be found in the PBMC fraction.
|description='''Peripheral blood mononuclear cell''' (PBMC) is a fraction of the leucocyte population in the blood composed by cells with round nucleus. PBMC consist of lymphocytes (T, B and NK cells) and monocytes. During extraction, neutrophils and platelets can be found in the PBMC fraction.
|info=[[MiPNet21.17 BloodCellsIsolation]]
|info=[[MiPNet21.17 BloodCellsIsolation]]
» [[#MiPNet21.17_BloodCellsIsolation|'''MiPNet article''']]
}}
}}


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==Cell Size==
== Cell size ==
* Lymphocytes: 210 fl of volume; 7 to 10 µm in diameter [1]
::::* Lymphocytes: 210 fl of volume; 7 to 10 µm in diameter [1]
::::* Monocytes: 180 fl of volume; 15 to 25 µm in diameter [2]


* Monocytes: 180 fl of volume; 15 to 25 µm in diameter [2]


== References ==
:::# [https://www.ncbi.nlm.nih.gov/pubmed/7214019| Segel GB, Cokelet GR, Lichtman MA (1981) The measurement of lymphocyte volume: importance of reference particle deformability and counting solution tonicity. Blood 57:894-9]
:::# [https://www.ncbi.nlm.nih.gov/pubmed/19919621| Mardi D, Fwity B, Lobmann R, Ambrosch A (2010) Mean cell volume of neutrophils and monocytes compared with C-reactive protein, interleukin-6 and white blood cell count for prediction of sepsis and nonsystemic bacterial infections. Int J Lab Hematol 32:410-8]


==References==
:::» [[O2k-Publications: PBMC]]
# [https://www.ncbi.nlm.nih.gov/pubmed/7214019| Segel GB, Cokelet GR, Lichtman MA (1981) The measurement of lymphocyte volume: importance of reference particle deformability and counting solution tonicity. Blood 57:894-9]
# [https://www.ncbi.nlm.nih.gov/pubmed/19919621| Mardi D, Fwity B, Lobmann R, Ambrosch A (2010) Mean cell volume of neutrophils and monocytes compared with C-reactive protein, interleukin-6 and white blood cell count for prediction of sepsis and nonsystemic bacterial infections. Int J Lab Hematol 32:410-8]

Revision as of 08:28, 3 March 2020


high-resolution terminology - matching measurements at high-resolution


PBMC

Description

Peripheral blood mononuclear cell (PBMC) is a fraction of the leucocyte population in the blood composed by cells with round nucleus. PBMC consist of lymphocytes (T, B and NK cells) and monocytes. During extraction, neutrophils and platelets can be found in the PBMC fraction.

Abbreviation: PBMC

Reference: MiPNet21.17 BloodCellsIsolation



Cell size

  • Lymphocytes: 210 fl of volume; 7 to 10 µm in diameter [1]
  • Monocytes: 180 fl of volume; 15 to 25 µm in diameter [2]


References

  1. Segel GB, Cokelet GR, Lichtman MA (1981) The measurement of lymphocyte volume: importance of reference particle deformability and counting solution tonicity. Blood 57:894-9
  2. Mardi D, Fwity B, Lobmann R, Ambrosch A (2010) Mean cell volume of neutrophils and monocytes compared with C-reactive protein, interleukin-6 and white blood cell count for prediction of sepsis and nonsystemic bacterial infections. Int J Lab Hematol 32:410-8
» O2k-Publications: PBMC