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Difference between revisions of "Pyruvate dehydrogenase"

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{{MitoPedia
|abbr=PDH
|description='''Pyruvate dehydrogenase''' is the first component enzyme of the [[pyruvate dehydrogenase complex]], which catalyzes oxidative decarboxylation of pyruvate in the mt-matrix, and yields acetyl-CoA. PDH is known as the mitochondrial gatekeeper in the core energy pathway of electron flow into the tricarboxylic acid cycle.
|info=[[Gnaiger 2020 BEC MitoPathways]], [[Hildyard 2003 Biochem J]]
}}
{{MitoPedia topics
|mitopedia topic=Enzyme
}}

Revision as of 18:28, 1 January 2021


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Pyruvate dehydrogenase

Description

Pyruvate dehydrogenase is the first component enzyme of the pyruvate dehydrogenase complex, which catalyzes oxidative decarboxylation of pyruvate in the mt-matrix, and yields acetyl-CoA. PDH is known as the mitochondrial gatekeeper in the core energy pathway of electron flow into the tricarboxylic acid cycle.

Abbreviation: PDH

Reference: Gnaiger 2020 BEC MitoPathways, Hildyard 2003 Biochem J


MitoPedia topics: Enzyme