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Difference between revisions of "Q-junction"

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{{MitoPedia
{{MitoPedia
|description=[[File:SUIT-catg FNSGp.jpg|right|300px|Q-junction]]
|description=[[File:SUIT-catg FNSGp.jpg|right|300px|Q-junction]]
The '''Q-junction''' is a junction for [[convergent electron flow]] in the [[Electron transfer-pathway]] (ET-pathway) from type N substrates and mt-matix dehydrogenases through [[Complex I]] (CI), from type F substrates and FA oxidation through [[electron-transferring flavoprotein complex]] (CETF),  from succinate (S) through [[Complex II]] (CII), from glycoreophosphate (Gp) through [[glycerophosphate dehydrogenase complex]] (CGpDH), from choline through [[choline dehydrogenase]], from dihydro-orotate through [[dihydro-orotate dehydrogenase]], and other enzyme complexes into the Q-cycle (ubiquinol/ubiquinone), and further downstream to [[Complex III]] (CIII) and CIV. The concept of the Q-junction, with the [[N-junction]] and [[F-junction]] upstream, provides the rationale for defining [[pathway control state]]s and [[categories of SUIT protocols]].
The '''Q-junction''' is a junction for [[convergent electron flow]] in the [[Electron transfer-pathway]] (ET-pathway) from type N substrates and mt-matix dehydrogenases through [[Complex I]] (CI), from type F substrates and FA oxidation through [[electron-transferring flavoprotein complex]] (CETF),  from succinate (S) through [[Complex II]] (CII), from glycoreophosphate (Gp) through [[glycerophosphate dehydrogenase complex]] (CGpDH), from choline through [[choline dehydrogenase]], from dihydro-orotate through [[dihydro-orotate dehydrogenase]], and other enzyme complexes into the Q-cycle (ubiquinol/ubiquinone), and further downstream to [[Complex III]] (CIII) and CIV. The concept of the Q-junction, with the [[N-junction]] and [[F-junction]] upstream, provides the rationale for defining [[Electron transfer-pathway state]]s and [[categories of SUIT protocols]].
|info=[[Gnaiger 2009 Int J Biochem Cell Biol]], [[Gnaiger 2014 MitoPathways]]
|info=[[Gnaiger 2009 Int J Biochem Cell Biol]], [[Gnaiger 2014 MitoPathways]]
}}
}}

Revision as of 12:17, 24 October 2017


high-resolution terminology - matching measurements at high-resolution


Q-junction

Description

Q-junction

The Q-junction is a junction for convergent electron flow in the Electron transfer-pathway (ET-pathway) from type N substrates and mt-matix dehydrogenases through Complex I (CI), from type F substrates and FA oxidation through electron-transferring flavoprotein complex (CETF), from succinate (S) through Complex II (CII), from glycoreophosphate (Gp) through glycerophosphate dehydrogenase complex (CGpDH), from choline through choline dehydrogenase, from dihydro-orotate through dihydro-orotate dehydrogenase, and other enzyme complexes into the Q-cycle (ubiquinol/ubiquinone), and further downstream to Complex III (CIII) and CIV. The concept of the Q-junction, with the N-junction and F-junction upstream, provides the rationale for defining Electron transfer-pathway states and categories of SUIT protocols.


Reference: Gnaiger 2009 Int J Biochem Cell Biol, Gnaiger 2014 MitoPathways


MitoPedia concepts: MiP concept, SUIT concept 


MitoPedia methods: Respirometry 


MitoPedia topics: Enzyme 

Contributed by Gnaiger E 2010-08-15; edited 2016-02-12, 2016-03-28.

Q-junction
Convergent NS-linked electron flow at the Q-junction, exerting an additive effect on flux, versus electron gaiting for separation of single N- and S-input pathways (upper panel: Gnaiger 2009; lower panel: Hatefi 1962 J Biol Chem-XLII). Modified Fig. 1.5 in Gnaiger 2014 MitoPathways.


More details: »Respiratory complexes - more than five
» O2k-Publications: Q-junction effect







Questions.jpg




Related MitoPedia pages

  • Electron transfer-pathway, ET-pathway
» Electron transfer-pathway
» Q-junction
  • Pathway control states
» Pathway control state
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E.jpg ET capacity
» Noncoupled respiration
» Is respiration uncoupled - noncoupled - dyscoupled?